ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…H9C2 cells were subjected to high glucose, high palmitic acid, or both high glucose and palmitic acid. db/db and streptozotocin (STZ)-induced diabetic mice were analyzed for ERK1/2 phosphorylation levels as well as the effects of U0126 treatment on cardiac remodeling. …”
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Predictors of a Good Outcome after Endovascular Stroke Treatment with Stent Retrievers by Ozcan Ozdemir, Semih Giray, Zulfikar Arlier, Demet Funda Baş, Yusuf Inanc, Ertugrul Colak

“…We need randomized trials to identify the significance of tight blood glucose control in clinical outcome during or after EVT.…”
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Cardiometabolic risk factors of post-bariatric patients two years after COVID-19 pandemic onset: a longitudinal study by Raysa Manuelle Santos Rocha, Márcia Ferreira Cândido de Souza, Danielle Villela Costa, Larissa Monteiro Costa Pereira, Jamille Oliveira Costa, Rosely de Jesus Nascimento, Andreia Ferreira de Aragão Rabelo, Alex Menezes dos Santos-Junior, Mario Francisco Dantas de Santana-Filho, André Luiz de Jesus Morais, Leonardo Baumworcel, José Rodrigo Santos Silva, Marcos Antonio Almeida-Santos, Antônio Carlos Sobral Sousa

“…Prepandemic weight regain rate was risk factor for increased fasting blood glucose. Two years after the pandemic onset, the study participants exhibited increased rates of weight regain, reduced excess weight loss, and an increase in fasting blood glucose and glycosylated hemoglobin parameters.…”
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Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation by Fan X, Liu S, Yu J, Hua J, Feng Y, Wang Z, Shen Y, Lan W, Wang J

“…KK/Upj-Ay/J (KKAy) mice and high glucose (HG)-induced AML12 cells were used to study the protective effect of Puerarin on DLI. …”
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Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling by Lingli Long, Yubin Li, Shuang Yu, Xiang Li, Yue Hu, Tengfei Long, Liqin Wang, Wenwen Li, Xiaoxin Ye, Zunfu Ke, Haipeng Xiao

“…HRECs were cultured in high glucose- (30 mM D-glucose) and hypoxia (cobalt chloride-treated)-stimulated diabetic condition to evaluate the antiangiogenic effects of SCU by CCK-8 test, cell migration experiment (wound healing and transwell), and tube formation experiment. …”
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Effect of ozone oil and non-surgical periodontal treatment in patients with type 2 diabetes. In-vivo and in-vitro studies with fibroblasts and Candida albicans by Raquel Alves do CARMO, Ana Carolina Organista CÖRNER, Eduardo Ferreira MARTINS, Gabriel OUVERNEY, Julio Cesar THURLER JÚNIOR, Bruno Kaufmann ROBBS, Vinicius D’Avila Bitencourt PASCOAL, Elisa ESPOSITO, Luciane Portas CAPELO, Gabriela Alessandra da Cruz Galhardo CAMARGO

“…Cell viability was lower in the high glucose Dulbecco’s modified Eagle’s medium (4500 mg/L) than in low glucose (1000 mg/L) (RM-ANOVA-p<0.0001). …”
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Shorter Digestion Times of Donor Islets Is Associated With Better Islet Graft Function After Islet Transplantation by Chia-Hao Wang, Christopher Orr, Jeannette Hacker-Stratton, Mohamed El-Shahawy, Keiko Omori, Meirigeng Qi, Fouad Kandeel

“…Although islet transplantation is effective in reducing severe hypoglycemia events and controlling blood glucose in patients with type 1 diabetes, maintaining islet graft function long-term is a significant challenge. …”
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The SGLT-2 Inhibitors and their Role in the Treatment of Heart Failure - A Review of Literature by Silvia Ciraolo, Agnieszka Kulczycka-Rowicka, Joanna Wojda, Katarzyna Lesiczka-Fedoryj, Anna Walczak, Zuzanna Kościuszko, Adam Sobiński, Matylda Czerwonka, Katarzyna Kurza, Julianna Podolec

“…The development of sodium-glucose cotransporter 2 (SGLT2) inhibitors has shown promising cardiovascular and renal benefits beyond glucose control. …”
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Longitudinal maternal glycemia during pregnancy and placental epigenetic age acceleration by Tesfa Dejenie Habtewold, Prabhavi Wijesiriwardhana, Richard J. Biedrzycki, Cuilin Zhang, Katherine L. Grantz, Jagteshwar Grewal, Fasil Tekola-Ayele

“…Abstract Background Dysregulation of maternal glucose homeostasis has been related to an increased risk of morbidity and mortality in mothers and fetuses, yet the mechanism remains unclear. …”
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Association of biochemical indicators with multimorbidity in 19,624 older adult individuals with chronic diseases: a study from Jindong District, Jinhua City, China by Qihuan Yao, Guozhong Chen

“…Multiple biochemical indicators were significantly associated with multimorbidity, particularly lipid parameters (low HDL-C and elevated TG), glucose parameters (elevated FBG and positive U-GLU), liver function (elevated ALT), and hemoglobin levels. …”
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Functional Status of Pancreatic α and β Cells in Type 2 Diabetes Mellitus Patients with Different Plasma Triglyceride Levels: A Retrospective Analysis by Hang Guo, Chunlei Ma, Xiaoming Wu, Congqing Pan

“…A reasonable control of the TG level makes it easier for blood glucose to reach the standard.…”
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Prescription pattern, glycemic control status, and predictors of poor glycemic control among diabetic patients with comorbid chronic kidney disease in Ethiopia: a facility-based cr... by Oumer Sada Muhammed, Minimize Hassen, Samuel Mamusha

“…Chronic kidney disease disrupts glucose metabolism and excretion, leading to pronounced and variable blood glucose fluctuations, thereby complicating diabetes management. …”
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Milled flaxseed-added diets ameliorated hepatic inflammation by reducing gene expression of TLR4/NF-κB pathway and altered gut microbiota in STZ-induced type 1 diabetic mice by Hui Xia, Xiangling Shi, Beijia Zhou, Jing Sui, Chao Yang, Hechun Liu, Ligang Yang, Shaokang Wang, Guiju Sun

“…The results showed that MF feeding 1) slightly decreased blood glucose levels and improved the ability of glucose tolerance by oral glucose tolerance test, 2) decreased liver tumor necrosis factor-α levels and increased liver glycogen levels with significance via down-regulating TLR4/NF-κB pathways, 3) and significantly altered some beneficial bacteria in gut microbiota. …”
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Some wood parameters in bulls administered vitamin c at different environmental temperatures by Tufan Keçeci, Ercan Keskin

“…Consequently, it was determined that the environmental temperatures caused to alter the values of the serum glucose, total cholesterol and AST in Swiss Brown cattle and vitamin C was not influenced on the investigated parameters at the ambient temperatures recorded this experiment.…”
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NFAT5 Contributes to Osmolality-Induced MCP-1 Expression in Mesothelial Cells by Christoph Küper, Franz-X. Beck, Wolfgang Neuhofer

“…Increased expression of the C-C chemokine monocyte chemoattractant protein-1 (MCP-1) in mesothelial cells in response to high glucose concentrations and/or high osmolality plays a crucial role in the development of peritoneal fibrosis during continuous ambulatory peritoneal dialysis (CAPD). …”
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Variables to Be Monitored via Biomedical Sensors for Complete Type 1 Diabetes Mellitus Management: An Extension of the “On-Board” Concept by Ignacio Rodríguez-Rodríguez, José-Víctor Rodríguez, Miguel-Ángel Zamora-Izquierdo

“…However, the recent development of continuous glucose monitoring (CGM) and new biomedical sensors/gadgets, based on automatic continuous monitoring, offers a new perspective on DM1 management, since these innovative devices allow the collection of 24-hour biomedical data in addition to blood glucose levels. …”
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Physicochemical Characterisation of Polysaccharides from the Seeds and Leaves of Miracle Fruit (Synsepalum dulcificum) and Their Antioxidant and α-Glucosidase Inhibitory Activities... by Huajun Jian, Fang Qiao, Jie Chen, Nongyue He

“…The results showed that MFP-S was a homogeneous polysaccharide (Mw 2804 Da) with glucose. MFP-L displayed three fractions (92093, 1496, and 237 Da) consisting of rhamnose, arabinose, galactose, glucose, and xylose. …”
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Design of hollow tapered PMMA polymeric microneedles for enhanced structural stability and drug delivery efficiency by Aswani Kumar Gera, Rajesh Kumar Burra

“…Flow rate analysis of water reports that 834.42 μl/min and 5396.94 μl/min and for glucose as 412 μl/min and 3648 μl/min, and that of insulin as 834 μl/min and 5244 μl/min for applied inlet pressure of 10 and 100 kPa, respectively. …”
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Metabolic Dysfunction in the Regulation of the NLRP3 Inflammasome Activation: A Potential Target for Diabetic Nephropathy by Wenli Zhao, Le Zhou, Petr Novák, Xian Shi, Chuang Biao Lin, Xiao Zhu, Kai Yin

“…A growing body of evidence suggests that high glucose, high fat, or other metabolite disorders can abnormally activate the NLRP3 inflammasome. …”
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Physiology-informed regularisation enables training of universal differential equation systems for biological applications. by Max de Rooij, Balázs Erdős, Natal A W van Riel, Shauna D O'Donovan

“…We also applied this technique to learn a representation of the rate of glucose appearance in the glucose minimal model using meal response data measured in healthy people. …”
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