The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP by Jonathan D. Douros, Jonathan N. Flak, Jonathan N. Flak, Patrick J. Knerr

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The Comparison of the Kidney Effects of Dipeptidyl Peptidase 4 Inhibitors and Glucagon-Like Peptide 1 Agonist-Administered Concomitant with Sodium-Glucose Cotransporter 2 Inhibitors in Japanese Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease by Kazuo Kobayashi, Masao Toyoda, Nobuo Hatori, Kazuyoshi Sato, Masaaki Miyakawa, Kouichi Tamura, Akira Kanamori

“…Strong evidence exists supporting the utility of sodium glucose cotransporter inhibitors (SGLT2is) for treating not only cardiovascular events but also renal events. …”
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Metformin in COVID-19: a magical role beyond the hyperglycemia by Gaurav Kumar Chaubey, Rahul Dilawari, Radheshyam Modanwal, Sharmila Talukdar, Asmita Dhiman, Manoj Raje

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Identification and Functional Characterization of P159L Mutation in in a Family with Maturity-Onset Diabetes of the Young 5 (MODY5) by Eun Ky Kim, Ji Seon Lee, Hae Il Cheong, Sung Soo Chung, Soo Heon Kwak, Kyong Soo Park

Subjects: “…glucose transporter type 2…”
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Impact of Dietary Intake and Cardiorespiratory Fitness on Glycemic Variability in Adolescents: An Observational Study by Mingliang Ge, Stephanie R Lebby, Shivani Chowkwale, Caleb Harrison, Grace M Palmer, Keith J Loud, Diane Gilbert-Diamond, Mary Ellen Vajravelu, Jennifer L Meijer

Subjects: “…continuous glucose monitoring…”
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Hypomagnesemia, insulin secretion and action in patients without diabetes, 1 year after kidney transplantation by Rasmus K. Carlsen, Anders Åsberg, Anders Åsberg, My Svensson, My Svensson, Kåre I. Birkeland, Kåre I. Birkeland, Hanne S. Jørgensen, Hanne S. Jørgensen, Iain Bressendorff, Hanne L. Gulseth, Hanne L. Gulseth, Karsten Midtvedt, Espen Nordheim, Espen Nordheim, Trond G. Jenssen

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Development and validation of machine learning models for MASLD: based on multiple potential screening indicators by Hao Chen, Jingjing Zhang, Xueqin Chen, Ling Luo, Wenjiao Dong, Yongjie Wang, Jiyu Zhou, Canjin Chen, Wenhao Wang, Wenbin Zhang, Zhiyi Zhang, Yongguang Cai, Danli Kong, Yuanlin Ding

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Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

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Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites by O. B. Shevelev, M. P. Moshkin

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Decreased Levels of Insulin-Regulated Aminopeptidase (IRAP) in Gestational Diabetes Mellitus: A Prospective Cohort Study by Osman Köse, Koray Gök, Elif Köse, Sezen Irmak Gözükara, Abdullah Tüten, Mehmet Sühha Bostancı

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Comparing the Efficacy and Safety of Glucagon-Like Peptide 1 Receptor Agonists with Sodium-Glucose Cotransporter 2 Inhibitors for Obese Type 2 Diabetes Patients Uncontrolled on Metformin: A Systematic Review and Meta-Analysis of Randomized Clinical Trials by Lu Ding, Bang Sun, Xinhua Xiao

“…Compared with SGLT-2is, treatment with GLP-1RAs achieved significant reduced HbA1c by 0.40% (95% CI: −0.54, −0.25; p<0.00001), fasting blood glucose (FBG) by 0.17 mmol/L (95% CI: −0.31, −0.04; p=0.01), and postprandial blood glucose (PBG) by 0.32 mmol/L (95% CI: −0.49, −0.14; p=0.0003) for obese T2D patients uncontrolled on metformin. …”
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The Impact of Selected Regimens of Chronic HIV‐Antiretroviral Treatment on Glycemic Control Markers and Correlates: A Systematic Review and Meta‐Analysis Protocol by Mlindeli Gamede, Mbulelo Aubrey Sosibo, Nontobeko Gumede, Mluleki Luvuno

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Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation by Iona Davies, Alice E. Adriaenssens, William R. Scott, David Carling, Kevin G. Murphy, James S. Minnion, Stephen R. Bloom, Ben Jones, Tricia M-M. Tan

Subjects: “…Glucose-dependent insulinotropic polypeptide receptor (GIPR)…”
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The road ahead: emerging therapies for primary IgA nephropathy by Edward J. Filippone, Rakesh Gulati, John L. Farber

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Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in ischemic rats by Sara Amiranda, Mariangela Succoio, Serenella Anzilotti, Ornella Cuomo, Tiziana Petrozziello, Valentina Tedeschi, Arianna Finizio, Giorgia Mele, Seppo Parkkila, Lucio Annunziato, Giuseppina De Simone, Giuseppe Pignataro, Agnese Secondo, Nicola Zambrano

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Associations between night-time sleep duration and fasting glucose and ratio of triglyceride to high-density lipoprotein cholesterol among adults free of type 2 diabetes or without diagnosed type 2 diabetes: a multicentre, cross-sectional study in China by Rong Zhang, Li Zhang, Qiang Li, Minying Zhang, Feng Liu, Shuo Chen, Yu-Jie Niu, Xin Qi, Chunjun Li, Jiangshan He, Chenglin Hong, Yuxue Wang, Yaqi Fan, Pei Guo, Binbin Zhang, Shitao Ma, Mianzhi Zhang

“…Objectives We aimed to assess the associations between night-time sleep duration and fasting glucose (FG), triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio and body mass index (BMI) among adults free of type 2 diabetes (T2D) or without diagnosed T2D.Design Cross-sectional study.Setting Medical examination centres at six hospitals in Beijing-Tianjin-Hebei region, China.Participants Participants were recruited via multistage, stratified cluster sampling. …”
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In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker by Akinrinde Akinleye, Koekemoer Trevor, Venter Maryna Van De, Bradley Graeme

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Cardiovascular disease risk prediction by Framingham risk score in women with polycystic ovary syndrome by Mina Amiri, Maryam Mousavi, Mahsa Noroozzadeh, Fereidoun Azizi, Fahimeh Ramezani Tehrani

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Is glucose‐induced hypersecretion of glicentin after the revision surgery using Roux‐en‐Y gastric bypass related to improved glycemic control due to insulin hypersecretion in a type 2 diabetes patient without diabetes remission after laparoscopic sleeve gastrectomy? by Yukako Yamamoto, Osamu Sekine, Jun Ito‐Kobayashi, Ayane Nishida, Takeshi Togawa, Yuki Ozamoto, Yasumitsu Oe, Akeo Hagiwara, Masaki Kobayashi, Tadahiro Kitamura, Masanori Iwanishi, Akira Shimatsu, Atsunori Kashiwagi

“…Interestingly, he showed improvements of insulin and a marked glicentin secretions with minor changes in glucagon related peptide 1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) secretions in the oral glucose tolerance test OGTT after the RYGB surgery compared with post‐LSG. …”
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Techno-Functional and Bioactive Properties and Chemical Composition of Guava, Mamey Sapote, and Passion Fruit Peels by Leticia X. López-Martínez, Mónica A. Villegas-Ochoa, J. Abraham Domínguez-Avila, Elhadi M. Yahia, Gustavo A. Gonzalez-Aguilar

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