Characteristics of Static Balance Function in Elderly Patients with Type 2 Diabetes Mellitus in Different Blood Pressure States by Shuai GUO, Zhizhen LIU, Jiawei QIN, Lianhua YIN, Jia HUANG, Jing TAO

“…Compared the difference of blood biochemical indicators in three groups, such as fasting blood glucose (FBG), glycosylated hemoglobin (GHbA1c), triglycerides (TG), total cholesterol (TC), high/low density lipoprotein (HDL/LDL), etc.; compared the difference of health-related indicators in three groups, such as blood pressure (BP) and pulse rate per minute; compared the difference of static balance function parameters in three groups, such as track length (LNG), surface of the statokine-sigram (SSKG), LNG/area, track length-X(LNG-X), track length-Y(LNG-Y), romberg quotient (RQ) and deviation amplitude (DA).Results:①Blood biochemical indexes: compared with the control group, FBG, GHbA1c, TG, TC and LDL in the T2DM group and T2DM-HTN group were higher (<italic>P</italic>&lt; 0.05); compared with T2DM group, FBG in the T2DM-HTN group was higher (<italic>P</italic>&lt; 0.05). ②Health-related indicators: compared with the control group, BMI, pulse rate per minute and systolic and diastolic blood pressure in the T2DM group and T2DM-HTN group were higher (<italic>P</italic>&lt; 0.05); compared with the T2DM group, BMI, pulse rate per minute and systolic and diastolic blood pressure in the T2DM-HTN group were higher (<italic>P</italic>&lt; 0.05). ③Static balance function parameters: At open eyes state, compared with the control group, LNG/area in the T2DM group was higher (<italic>P</italic>&lt; 0.05), LNG, SSKG, LNG/area, LNG-X and LNG-Y in the T2DM group were higher (<italic>P</italic>&lt; 0.05); Compared with the T2DM group, LNG, LNG/area, LNG-X and LNG-Y in the T2DM-HTN group were higher (<italic>P</italic>&lt; 0.05). …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Consequently, we studied the mechanism of the Met-induced antitumor effect. Expressions of glucose transporter (Glut)-1, mitochondrial reactive oxygen species (mtROS), interferon (IFN)-γ, Ki67, autophagy markers, activation markers for NF-E2-related factor 2 (Nrf2), and mammalian target of rapamaycin complex 1 (mTORC1) in CD8+ tumor-infiltrating T lymphocytes (CD8TILs) were examined by flow cytometry analysis. …”
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Improved performance of botia fish Chromobotia macracanthus with the utilization of blood clam shell in the recirculation system by Rani Ria Rizki, Iis Diatin, Tatag Budiardi, Irzal Effendi

“…The stress response of botia blood glucose and TKO fluctuates with environmental changes. …”
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Insulin resistance surrogates are associated with all-cause mortality and cardiovascular mortality in population with metabolic syndrome: a retrospective cohort study of NHANES by Jinhao Liao, Linjie Wang, Lian Duan, Fengying Gong, Huijuan Zhu, Hui Pan, Hongbo Yang

“…Abstract The study aimed to assess the association of five insulin resistance surrogates, namely HOMA-β (Homeostasis Model Assessment of Beta-cell Function), QUICKI (Quantitative Insulin Sensitivity Check Index), IGR (Insulin Glucose Ratio), e-IS (Estimated Insulin Sensitivity), and Bennett ISI(Bennett’s insulin sensitivity index) with all-cause and cardiovascular mortality in respondents with metabolic syndrome(MetS). …”
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Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway by Zhu Xuexue, Meng Xinyu, Du Xinyao, Zhao Chenyang, Ma Xinyu, Wen Yuanyuan, Zhang Shijie, Hou Bao, Cai Weiwei, Du Bin, Han Zhijun, Xu Fei, Qiu Liying, Sun Haijian

“…Moreover, VAC treatment effectively suppresses the process of epithelial-mesenchymal transition (EMT), a crucial characteristic of renal fibrosis, in high glucose (HG)-induced HK-2 cells. …”
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Circulating Stress Hormones, Brain Health, and Cognition in Healthy Older Adults: Cross-Sectional Findings and Sex Differences in Age-Well by Maxie Liebscher, Silke White, Simon Hass, Anne Chocat, Florence Mezenge, Brigitte Landeau, Marion Delarue, Oriane Hébert, Anne-Laure Turpin, Natalie L. Marchant, Gaël Chételat, Olga Klimecki, Géraldine Poisnel, Miranka Wirth, Claire André, Pierre Champetier, Léa Chauveau, Fabienne Collette, Sophie Dautricourt, Robin de Flores, Vincent De La Sayette, Harriet Demnitz-King, Séverine Fauvel, Francesca Felisatti, Victor Ferment, Eglantine Ferrand-Devouge, Julie Gonneaud, Antoine Garnier-Crussard, Anaïs Hamel, Sacha Haudry, Pierre Krolak-Salmon, Elizabeth Kuhn, Valérie Lefranc, Antoine Lutz, Valentin Ourry, Cassandre Palix, Anne Quillard, Géraldine Rauchs, Eric Salmon, Edelweiss Touron, Patrik Vuilleumier, Tim Whitfield

“…AD-sensitive measures of brain health, including glucose metabolism (n = 89), cerebral perfusion, gray matter volume, amyloid deposition in a priori regions of interest, and cognitive markers were evaluated. …”
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Identifying pre-diabetes ‘hotspots’ in Northern California using geospatial analysis: opportunities to target diabetes prevention strategies and improve health equity by Tannaz Moin, Luis A Rodriguez, Obidiugwu Kenrik Duru, Julie Schmittdiel, Tainayah W Thomas, Maher Yassin, Yelba Castellon-Lopez

“…We used health system and census data to identify pre-diabetes hotspots using a systematic five-step geoprocessing approach that made use of incremental spatial autocorrelation and Getis-Ord Gi*.Setting This study was set in Kaiser Permanente Northern California (KPNC), an integrated health delivery system with over four million members.Participants KPNC adults ages 35–70 who underwent a haemoglobin A1c (HbA1c) or fasting plasma glucose (FPG) screening test in 2019 were mapped to census tracts in Northern California. …”
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Reduction of intestinal RIPK1 ameliorates HFD-induced metabolic disorders in female mice by Ye Yuan, Xiaomin Hu, Chunguang Guo, Yihua Xu, Shihan Li, Wei Wen, Xinli Hu, Fanxin Zeng, Weiyi Cui, Wenli Chen, Xueting Sun, Ning Hou, Jue Wang, Rui-Ping Xiao, Xiuqin Zhang

“…Accordingly, HFD-induced metabolic disorders, including obesity, impaired glucose tolerance, insulin resistance, and dyslipidemia, are significantly ameliorated in the Ripk1IEC+/− female mice. …”
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Twenty-four weeks of combined training in different environments, aquatic and land, in the type 2 diabetes management (Aquatic and Land Exercise for Diabetes -ALED): protocol of a... by Larissa dos Santos Leonel, Ingrid Alessandra Victoria Wolin, Angélica Danielevicz, Mabel Diesel, Marina Isolde Constantini, João Batista de Oliveira Junior, Allana Andrade Souza, Thaís Reichert, João Gabriel Silveira-Rodrigues, Danusa Dias Soares, Marcelo Fernando Ronsoni, Simone Van De Sande Lee, Alex Rafacho, Guilherme Fleury Fina Speretta, Karla Siqueira Lottermann, Josefina Bertoli, Alexandre Pastoris Muller, Aline Mendes Gerage, Cíntia de La Rocha Freitas, Rodrigo Sudatti Delevatti

“…Throughout the 24 weeks, the training load date and acute capillary glucose and blood pressure measurements will also be conducted. …”
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The comparative analysis of the influence of bisoprolol and carvedilol on the course of heart failure of ischemic origin in patients with concomitant atrial fibrillation and diabet... by N.M. Kulaiets, V.M. Kulaiets

“…The levels of thyroid-stimulating hormone, free triiodothyronine and free thyroxine, glucose, glycated hemoglobin, galectin-3, suppression of tumorigenicity 2 peptide, B-type natriu­retic peptide, N-terminal prohormone of brain natriuretic peptide were determined. …”
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The Interactive Effects of Fruit Intake Frequency and Serum miR-484 Levels as Biomarkers for Incident Type 2 Diabetes in a Prospective Cohort of the Spanish Adult Population: The D... by Ana Lago-Sampedro, Wasima Oualla-Bachiri, Cristina Maldonado-Araque, Sergio Valdés, Inmaculada González-Molero, Viyey Doulatram-Gamgaram, Elias Delgado, Felipe J. Chaves, Luis Castaño, Alfonso Calle-Pascual, Josep Franch-Nadal, Gemma Rojo-Martínez, Sara García-Serrano, Eva García-Escobar

“…<b>Background/Objectives</b>: Although evidence suggests that miR-484 and several fruit components are involved in glucose metabolism and insulin resistance metabolic pathways, the relationship between serum miR-484 levels and fruit consumption in relation to the risk of Type 2 diabetes (T2DM) remains elusive. …”
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Indirect effects of serum metabolites in the influence of the DASH diet on systolic blood pressure: The Taizhou imaging study by Yawen Wang, Yi Zheng, Xin Zhang, Jincheng Li, Yucan Li, Chengjun Zhang, Ningxin Gao, Jiacheng Wang, Min Fan, Weizhong Tian, Yanfeng Jiang, Yingzhe Wang, Mei Cui, Chen Suo, Tiejun Zhang, Li Jin, Xingdong Chen, Kelin Xu

“…Moreover, acetic acid and glucose demonstrated significant mediation effects in the parallel mediation model (The proportion of mediation effect was 22.87 %). …”
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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…Mice were evaluated for anxiety-like behavior, exploration and locomotor activity in the open field test, as well as glucose tolerance and histological indicators of hepatic steatosis. …”
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Soybean oil, a linoleic acid source, in lamb diets: metabolic, feeding behavior, and ruminal parameters by V. G. O. Lima, L. O. da Silva, J. E. de Freitas Jr., H. D. R. Alba, V. M. Leite, W. P. Silva, D. D. S. Pina, L. C. Leite, C. S. Rodrigues, S. A. Santos, G. G. P. de Carvalho

“…The data were analyzed using linear and quadratic polynomial contrasts, except for the ruminal fermentation parameters and plasma glucose, which were analyzed using repeated measures over time. …”
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Inhibition of platelet activation alleviates diabetes-associated cognitive dysfunction via attenuating blood-brain barrier injury by Fuxing Xu, Juan Hu, Xuying Li, Lan Yang, Shiqiu Jiang, Tao Jiang, Bo Cheng, Hailiang Du, Ruiduo Wang, Yingying Deng, Wei Gao, Yansong Li, Yaomin Zhu

“…In vitro, mouse brain microvascular endothelial cell line (b.End3) were exposed to CD40L for 24 h at 5.5 mM or 30 mM glucose media after silencing CD40 and HIF1α or not to investigate the effects of CD40 on BBB disruption and the underlying molecular pathways. …”
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Clinical Characteristics of Fulminant Type 1 Diabetes Compared with Typical Type 1 Diabetes: One-Year Follow-Up Study from the Guangdong T1DM Translational Medicine Study by Daizhi Yang, Yongwen Zhou, Sihui Luo, Xueying Zheng, Ping Ling, Liling Qiu, Wen Xu, Hua Liang, Bin Yao, Jianping Weng, Jinhua Yan

“…FT1DM patients had higher plasma glucose levels and higher percentage of diabetes ketoacidosis (P<0.001, respectively). …”
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Association between non-insulin-based insulin resistance surrogate makers and Helicobacter pylori infection: a population-based study by Jiayu Qiu, Yueming Yu, Dingwei Liu, Sihai Chen, Youhua Wang, Jianxiang Peng, Jinliang Xie, Chengyun Wu, Feng Zhou, Hui Fang, Qirui Lai, Yong Xie

“…This study aimed to investigate the association between non-insulin-based surrogate markers of IR, including the triglyceride glucose (TyG) index, triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, and the metabolic score for IR (METS-IR), and H. pylori infection in U.S. populations. …”
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The synergetic effect of selenium or zinc oxide nanoparticles with chromium on mitigating thermal stress for sustainable production and improving antioxidant capacity and inflammat... by I. T. El-Ratel, K. H. El-Kholy, S. M. Elgmmal, S. F. Fouda, A.-K. E. Abdel-Khalek, M. A. Hassan, M. M. Azzam, M. Alagawany, A. Lestingi

“…Albumin was significantly increased, while glucose, creatinine, and urea were significantly decreased in response to ZnONPs and SeNP–Cr or ZnONP–Cr combinations compared<span id="page44"/> with the other groups. …”
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Effectiveness of acupuncture on glycolipid metabolism in patients with coronary heart disease: A systematic review and meta-analysis by Yuxin Sun, Yu Liu, Jian Xiong, Xiao Li, Ying Wei, Qianhua Zheng, Xiang Li, Wenchuan Qi, Fanrong Liang

“…Only RCTs that included acupuncture as a sole or secondary effect on glucose-lipid metabolism in coronary heart disease were included.Our primary outcome indicators were Low-density lipoprotein cholesterol(LDL-C), Hemoglobin A1c(HbA1c). …”
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

“…Results of gene ontology analysis identified two biological pathways namely skeletal system development and calcium channel complex with two important KEGG pathways including glucagon signaling pathway and AMPK signaling pathway which play an important role in glucose metabolism and homeostasis and skeletal system development. …”
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