Glucagon-Like Peptide-1 Receptor Agonist Liraglutide Ameliorates the Development of Periodontitis by Noritaka Sawada, Kei Adachi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Shuichiro Kobayashi, Shin-ichi Miyajima, Yuki Suzuki, Takeshi Kikuchi, Makoto Mizutani, Taku Toriumi, Masaki Honda, Akio Mitani, Tatsuaki Matsubara, Keiko Naruse

“…These results highlight the beyond glucose-lowering effects of liraglutide on the treatment of periodontitis.…”
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Development and Validation of a Nomogram to Predict Type 2 Diabetes Mellitus in Overweight and Obese Adults: A Prospective Cohort Study from 82938 Adults in China by Qingqing Liu, Jie Yuan, Maerjiaen Bakeyi, Jie Li, Zilong Zhang, Xiaohong Yang, Fangming Gao

“…Six independent risk factors of T2DM were identified and entered into the nomogram including age, body mass index, fasting plasma glucose, total cholesterol, triglycerides, and family history. …”
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Neonatal outcomes in offspring of mothers with pregestational diabetes: a hospital-based multicentre prospective cohort study protocol by Manu Raj, Vishnu Renjith, Renjitha Bhaskaran, Anju Philip Thurkkada, Radhamany Kunjukutty, Sobha S Nair, Annie Soman, Sethulakshmi Ramachandran

“…PGDM will be diagnosed by the following criteria—FBS ≥126 mg% OR HbA1c ≥6.5 mg% OR Random blood glucose ≥200 mg% on the initial visit or documented prior to the index pregnancy. …”
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Disorders of circadian rhythms of heart rate variability in diabetic cardiac autonomic neuropathy: mechanisms and consequences by V.A. Serhiyenko, M.I. Dolynay, V.B. Sehin, Y.V. Lazur, A.A. Serhiyenko

“…Misalignment of circadian rhythms has been evidenced in patients with DM, and there is a close relationship between alterations in neuroendocrine sleep architecture, circadian clock oscillations, glucose metabolism, autonomic function, and diurnal profiles of blood pressure and heart rate. …”
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Construction of an Interpretable Model of the Risk of Post-Traumatic Brain Infarction Based on Machine Learning Algorithms: A Retrospective Study by Li S, Li H, Wu B, Pan R, Liu Y, Wang J, Wei D, Gao H

“…The interpretations of the ML models’ predictions were provided by SHAP values.Results: Key predictors included age, bilateral brain contusions, platelet count, uric acid, glucose, traumatic subarachnoid hemorrhage, and surgical treatment. …”
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The Association between Antihypertensive Medication Use and Blood Pressure Is Influenced by Obesity by Jash S. Parikh, Arshdeep K. Randhawa, Sean Wharton, Heather Edgell, Jennifer L. Kuk

“…Diastolic BP differences between women ARB users and NoBPMed were also greatest in obesity (−5 ± 1 mmHg) (P<0.05) whilst there were no differences in normal weight individuals (−1 ± 1 mmHg) (P>0.05). Furthermore, glucose levels and waist circumference in women were higher in those using ACE inhibitors compared to diuretics (P<0.05). …”
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Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling by Ying Cheng, Man Zhang, Chenguang Li, Long Su, Lingli Fu, Shi Wu, Chaofei Xu, Bei Sun, Liming Chen

“…Additionally, we discover that sodium-glucose cotransporter 2 inhibitors (SGLT2i) could inhibit the AGGF1 signalling pathway early to achieve therapeutic effects. …”
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Insulin Treatment Perception and Factors affecting the Acceptance in Type 2 Diabetes Mellitus Patients attending a Specialist Clinic in Ilorin, Nigeria by Olalekan A. Agede, John Kola Olarinoye, James Ayodele Ogunmodede, Nasiru Sanni, Matthew Olumuyiwa Bojuwoye, Christopher Muyiwa Opeyemi, Mary Olufunmilayo Ologe, Dapo S Oyedepo

“…Some insulin-experienced patients had positive perceptions of insulin, like their belief in insulin’s health benefits (p = 0.001) and ability to control blood glucose (p = 0.048). Insulin-naive individuals exhibited more negative attitudes toward insulin, emphasizing the need for targeted interventions and patients’ health education. …”
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Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A^y) mutation by E. N. Makarova, T. V. Yakovleva, N. Yu. Balyibina, K. O. Baranov, E. I. Denisova, A. D. Dubinina, N. A. Feofanova, N. M. Bazhan

“…In control Ay -mice, expression of genes involved in lipid and glucose metabolism (Ppargc1a, Cpt1, Pck1, G6p, Slc2a2) in the liver and genes involved in lipogenesis (Pparg, Lpl, Slc2a4) in visceral adipose tissue was higher in females than in males, and FGF21 administration inhibited the expression of these genes in females. …”
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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. by Menglu Ouyang, Anila Anjum, Francisca Gonzalez Mc Cawley, Mohammad Wasay, Lu Ma, Xin Hu, Xiaoying Chen, Alejandra Malavera, Xi Li, Paula Muñoz Venturelli, H Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Octavio M Pontes-Neto, Carlos Abanto, Venessa Cano-Nigenda, Antonio Arauz, Chao You, Stephen Jan, Lili Song, Craig S Anderson, Hueiming Liu, INTERACT3 Investigators

“…The INTERACT3 Care Bundle included time- and target-based protocols for the management of early intensive lowering of systolic blood pressure (SBP, target <140mmHg), glucose control (target 6.1-7.8 mmol/L in those without diabetes and 7.8-10.0 mmol/L in those with diabetes), anti-pyrexia treatment (target body temperature ≤37.5°C), and the rapid reversal of warfarin-related anticoagulation (target international normalized ratio <1.5). …”
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Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae by Tien-Huang Lin, Chen-Yu Wang, Chien-Chen Wu, Ching-Ting Lin

“…Results: Deletion of ackA in K. pneumoniae CG43S3 led to AcP accumulation, while pta deletion abolished AcP synthesis when grown in TB7+1 % glucose. This pathway influenced global protein acetylation, with pta deletion decreasing acetylation and ackA deletion increasing it. …”
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Association between the Plasma-Glycosylated Hemoglobin A1c/High-Density Lipoprotein Cholesterol Ratio and Carotid Atherosclerosis: A Retrospective Study by Xiangming Hu, Wei Li, Chenyang Wang, Haotian Zhang, Haoyu Lu, Guang Li, Yingling Zhou, Haojian Dong

“…As a novel compound indicator for evaluating blood glucose homeostasis and dyslipidemia, the HbA1c/HDL-C ratio was positively correlated with carotid atherosclerosis evaluated using the mean and maximum cIMT as well as the carotid artery plaque burden.…”
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Prevention and Reversal of Diabetes by All-Trans Retinoid Acid and Exendin-4 in NOD Mice by Jyuhn-Huarng Juang, Yang-Hau Van, Chien-Hung Kuo, Mei-Yin Lin, Ying-Hsiu Liu, Han-Ying Chang

“…ATRA and/or exendin-4 treatment did not alter their blood glucose levels and survival. Our results indicate that, before the onset of autoimmune diabetes, ATRA and exendin-4 treatment alone preserves pancreatic beta cells; ATRA and ATRA plus exendin-4 treatment delays the onset of autoimmune diabetes. …”
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Secular trends of epidemiologic patterns of chronic kidney disease over three decades: an updated analysis of the Global Burden of Disease Study 2019 by Jing Liu, Xue Li, Yongping Liu, Xiaodong Sun, Xiaojin Feng, Ningning Hou, Zhenna Chen

“…Among risk factors, metabolic risk factors, especially systolic blood pressure, fasting plasma glucose and body mass index, were the main contributors to CKD-related deaths. …”
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Gestational weight gain patterns as predictors of cesarean deliveries in women diagnosed with gestational diabetes mellitus by Tzu-Ling Chen, Su-Fen Cheng, Chien-Lin Kuo, Chu-Yu Huang, Chia-Hsun Wu

“…GDM was diagnosed by oral glucose tolerance test (OGTT) during 24–28 weeks of gestation. …”
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Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with brucellosis resistance/susceptibility in Shami goat by Ahmed A. Elsayed, Ahmed M. Sallam

“…On the other hand, there were significant reductions in the glucose, total protein albumin, urea, calcium, inorganic phosphorus, sodium, copper, zinc, iron, TAC, GSH, SOD, GPx, IL-10 and fibrinogen in the infected compared to the non-infected does. …”
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Intercropping of Saccharum spp. with Dictyophora indusiata: effects on microbial communities and metabolite profiles during bagasse degradation by Mingzheng Duan, Mingzheng Duan, Xiaojian Wu, Shengfeng Long, Hairong Huang, Xiang Li, Yijie Li, Changning Li, Bin Feng, Jiafu Chen, Defa Zhong, Zhendong Chen, Zeping Wang

“…Key metabolites, such as glucose, cellobiose, and D-mannose, were more abundant in DIBA samples. …”
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Patients’ and family members’ knowledge, attitudes and perceived family support for SMBG in type 2 diabetes: a fuzzy-set qualitative comparative analysis by Jun Lu, Xiaohong Li, Qian Zhao, Ying Guo, Xinying Yu, Yuheng Feng, Yuxi Zhao

“…Aims and objectives To examine the combined effects of the patient’s and family members’ knowledge, attitudes and perceived family support on self-monitoring of blood glucose (SMBG) behaviour of patients with type 2 diabetes.Design A cross-sectional design using the framework of knowledge–attitude–behaviour (KAB) combined with family support.Setting Shanghai, China.Participants Seventy type 2 diabetes patient–family member dyads recruited from 26 residential committees in Shanghai were investigated. …”
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Diabetes Mellitus and HIV Infection among Newly Diagnosed Pulmonary Tuberculosis Patients in the North West Region of Cameroon: A Cross-Sectional Study by Leonard Fonkeng Sama, Sidoine Sadjeu, Thibau Flaurant Tchouangueu, Solange Dabou, Georges Ful Kuh, Omer Bebe Ngouateu, Michel Noubom

“…After the TB diagnosis was done, fasting blood glucose, 2 h-PG test, HbA1c, and biochemical enzymatic tests were performed for the diagnosis of diabetes. …”
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Levels of blood pressure, cardiovascular biomarkers and their correlations in women with previous pre-eclamptic pregnancy within 7 years postpartum: a cross-sectional study in Thai... by Tippawan Liabsuetrakul, Annetine Staff, Jarawee Sukmanee, Penkae Rothmanee, Wilaiwan Sriwimol

“…Eligible women were interviewed, examined for body mass index (BMI) and blood pressure, and donated morning spot urine and blood samples.Primary outcome measures Serum high-sensitivity C reactive protein, creatinine, fasting blood glucose (FBS), glycated haemoglobin (HbA1c), low-density lipoprotein (LDL) cholesterol, urine microalbumin to creatinine ratio (UACR) and sodium were measured. …”
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