-
3201
Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus
Published 2025-02-01“…Abstract Magnesium (Mg) is a vital trace element in cellular processes, including glucose metabolism and insulin action. This study aimed to assess the prevalence of dysmagnesemia among patients with type 2 diabetes mellitus (T2DM) and its relationship with glycaemic control and diabetic complications. …”
Get full text
Article -
3202
Long term cost-effectiveness analysis of IDegLira in the treatment of type 2 diabetes patients compared to GLP-1RA added to basal insulin after IDegLira entered the national reimbu...
Published 2025-01-01“…The baseline and clinical efficacy data in the model are from the EXTRA study. The cost includes glucose-lowering medication, background treatment cost, and complication treatment costs. …”
Get full text
Article -
3203
Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice
Published 2025-01-01“…Inhibition of mTOR during hypoxia/reoxygenation (H/R) injury restored RILP expression and attenuated cellular injury in cardiomyocytes cultured with high glucose.ConclusionFollowing I/RI in diabetic myocardium, an increase in the CM1 subpopulation and a reduction in RILP expression result in impaired autophagic flux. …”
Get full text
Article -
3204
Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes
Published 2025-02-01“…In this study the predictive value of early metabolic response after TIL therapy is explored.Materials and methods: 60 patients treated with TIL therapy in 4 different clinical trials and with available [18F]2-fluoro-2-deoxy-d-glucose positron emission tomography-CT (FDG-PET/CT) scans at baseline and at least one follow-up scan 6–8 weeks and/or 12–16 weeks post-TIL infusion were included.Results: Obtaining complete metabolic response (CMR) was associated with significantly superior median overall survival (mOS) compared with not obtaining CMR (p<0.0001). …”
Get full text
Article -
3205
Higher gut Bacteroidetes and Actinobacteria population in early pregnancy is associated with lower risk of gestational diabetes in the second trimester
Published 2025-02-01“…Higher Firmicutes to Bacteroidetes ratio in the gut of mothers was associated with fasting and 1-h glucose intolerance in the screening time.…”
Get full text
Article -
3206
The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer
Published 2020-01-01“…The functions of the PPAR family (PPARA, PPARD, and PPARG) and their coactivators (PPARGC1A and PPARGC1B) in maintenance of lipid and glucose homeostasis have been unveiled. However, the roles of PPARs in cancer development remain elusive. …”
Get full text
Article -
3207
Isolation and Characterization of Exopolysaccharide-Producing Lactobacillus plantarum SKT109 from Tibet Kefir
Published 2015-12-01“…The EPS was isolated and purified, and it was shown to consist of fructose and glucose in an approximate molar ratio of 3:1, with an average molecular weight of 2.1×106 Da. …”
Get full text
Article -
3208
Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr...
Published 2022-07-01“…The primary outcomes are changes in fasting blood glucose, glycosylated haemoglobin, self-management knowledge and behaviour, and medication adherence from baseline to the 3rd and 6th months. …”
Get full text
Article -
3209
GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation
Published 2025-01-01“…The underlying mechanisms of occludin changes associated with GYY4137 were investigated using oxygen-glucose deprivation / reoxygenation (OGD/R) model. …”
Get full text
Article -
3210
Pharmacogenetics: Influence of CYP2C9*2 and *3 alleles polymorphisms on Iraqi type 2 diabetic patients
Published 2024-01-01“…Allele specific amplification-polymerase chain reaction was used to genotype the CYP2C9 gene. Fasting serum glucose, fasting insulin, and glycated hemoglobin (HbA1c) levels were measured as part of the biochemical analysis. …”
Get full text
Article -
3211
Incidence of diabetic retinopathy and predictors among adult patients with diabetes in central and southern Ethiopia: a multicentre retrospective cohort study
Published 2025-01-01“…The best strategy to protect our eyesight from DR is to control high glucose level and giving due attention to high-risk individuals with diabetes. …”
Get full text
Article -
3212
Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systematic review and meta-analysis
Published 2025-01-01“…The expression and hepatic clearance of insulin and subsequent glucose homeostasis are mediated by TCF7L2 via Wnt signaling. …”
Get full text
Article -
3213
Intravitreal dexamethasone implant (Ozurdex®) findings over time: ultrasound and ultra-widefield fundus photography
Published 2025-01-01“…These alterations evidenced in the Ozurdex® implant over time may be related to the degradation of the glucose polymer structure.…”
Get full text
Article -
3214
Artificial intelligence‐based body composition analysis using computed tomography images predicts both prevalence and incidence of diabetes mellitus
Published 2025-02-01“…In subjects with normal glucose tolerance, higher VF proportion and VF/SF ratio were associated with higher risk of developing prediabetes or diabetes (adjusted HR 1.3 [95% CI 1.1–1.4] in men; 1.4 [1.2–1.7] in women). …”
Get full text
Article -
3215
Neonatal and Maternal Risk Factors for Indirect Hyperbilirubinemia: A Cross-Sectional Study from Bahrain
Published 2022-01-01“…ABO incompatibility was the commonest risk factor for neonatal indirect hyperbilirubinemia (n=152, 37.6%) followed by glucose-6-phosphate dehydrogenase (G6PD) deficiency (n=130/400, 32.5%). …”
Get full text
Article -
3216
Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model
Published 2025-01-01“…LASSO regression identified the following 11 features closely related to aCCI: age, respiratory rate, base excess, glucose, red blood cell distribution width (RDW), alkaline phosphatase (ALP), whole blood potassium, hematocrit (HCT), phosphate, creatinine, and mean corpuscular hemoglobin (MCH). …”
Get full text
Article -
3217
Physiological Properties of Dietary Ellagitannin-Rich Preparations Obtained from Strawberry Pomace Using Different Extraction Methods
Published 2015-09-01“…It could be concluded that more efficient acetone extraction of strawberry pomace increased the content of both ellagitannins and proanthocyanidins in the polyphenolic preparation, which caused a stronger inhibiting effect on caecal fermentation processes and at the same time lowered blood triacylglycerols and glucose level. Considering the equal content of ellagitannins in both supplemented diets, it may be speculated that the above effects were due to the presence of proanthocyanidin fraction.…”
Get full text
Article -
3218
Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes
Published 2020-01-01“…Age, educational level, duration of diabetes, fasting blood glucose (FBG), HbA1c, total cholesterol (TC), triglyceride (TG), and 24-hour urine protein were significantly associated with cognitive impairment in T2DM patients of advanced age. …”
Get full text
Article -
3219
Epidemiologic features of non-alcoholic fatty liver disease in Russia
Published 2014-10-01“…Investigation included general (anthopometrical), laboratory and instrumental investigations, such as assessment of hepatites B and C markers, liver transaminases, gamma-glutamyltranspeptidase, blood lipid spectrum, glucose level, and abdominal ultrasound investigation, if required — esophagogastroduodenoscopy. …”
Get full text
Article -
3220
Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction
Published 2025-01-01“…Additionally, the oxygen-glucose deprivation/reperfusion (OGD/R) model was developed in endothelial cells to simulate myocardial I/R injury in vitro. …”
Get full text
Article