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3081
Association of PPAR Alpha Intron 7 G/C, PPAR Gamma 2 Pro12Ala, and C161T Polymorphisms with Serum Fetuin-A Concentrations
Published 2017-01-01“…Both peroxisome activator proteins (PPARs) and fetuin-A play a role in lipid and glucose metabolism. Aims. We investigated whether PPARα intron 7 G2468/C and PPARγ2 Pro12Ala and PPARγ exon 6 C161T polymorphisms are associated with serum fetuin-A concentrations. …”
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3082
AICAR Protects against High Palmitate/High Insulin-Induced Intramyocellular Lipid Accumulation and Insulin Resistance in HL-1 Cardiac Cells by Inducing PPAR-Target Gene Expression
Published 2015-01-01“…AICAR treatment induced the expression of Acadvl and Glut4, which correlated to prevention of the HP/HI-induced intramyocellular lipid build-up, and attenuation of the HP/HI-induced impairment of glucose uptake. These data support the hypothesis that AICAR contributes to cardiac metabolic adaptation via regulation of transcriptional mechanisms.…”
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3083
Solution combustion synthesis of ZnO doped CuO nanocomposite for photocatalytic and sensor applications
Published 2025-01-01“…The electrochemical properties of the prepared NPs were studied using cyclic voltammetry and electrochemical impedance spectroscopy (EIS). Solutions of glucose and ascorbic acid were effectively sensed using modified carbon paste electrodes. …”
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3084
Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome
Published 2025-01-01“…Fifty rats were randomly assigned into five groups of 10 rats each: Control, PCOS, PCOS + FMN (15 mg/kg), PCOS + FMN (30 mg/kg), and PCOS + FMN (60 mg/kg). Fasting blood glucose, insulin, luteinizing hormone, follicle-stimulating hormone, testosterone, and estradiol were detected in DHEA-induced PCOS rats. …”
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3085
GLP-1 Receptor Agonists’ Impact on Fertility - A Review
Published 2025-02-01“…They have proven their ability to impact a variety of hormonal as well as metabolic pathways. They manage glucose metabolism, appetite, as well as insulin secretion. …”
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3086
New Genomic Approaches to Enhance Biomass Degradation by the Industrial Fungus Trichoderma reesei
Published 2018-01-01“…We also discuss new perspectives about control of secretion and cellulase expression based on RNA-seq and functional characterization data of T. reesei growth in different carbon sources, which comprise glucose, cellulose, sophorose, and sugarcane bagasse.…”
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3087
Effects of Synthetic Procedures and Postsynthesis Incubation pH on Size, Shape, and Antibacterial Activity of Copper (I) Oxide Nanoparticles
Published 2020-01-01“…Copper (I) oxide nanoparticles (Cu2O NP) were synthesized by reducing CuSO4 with glucose in the presence of polyvinyl alcohol as a capping agent. …”
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3088
Histological, physiological and transcriptomic analysis in hepatopancreas of Procambarus clarkii under heat stress
Published 2025-01-01“…Heat stress notably altered the expression of genes related to glucose, lipid, and protein metabolism, as well as oxidative phosphorylation pathways. …”
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3089
A simple and highly efficient protocol for 13C-labeling of plant cell wall for structural and quantitative analyses via solid-state nuclear magnetic resonance
Published 2025-01-01“…The protocol is based on a convenient and easy setup to supply both 13C-labeled glucose and 13CO2 using a vacuum-desiccator. The protocol does not require large amounts of 13CO2. …”
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3090
lncRNA NEAT1 Downregulation Ameliorates the Myocardial Infarction of Mice by Regulating the miR-582-5p/F2RL2 Axis
Published 2022-01-01“…The infarct area, pathological changes, and cell apoptosis in mouse myocardial tissue were evaluated using triphenyltetrazolium chloride and Evans blue, hematoxylin-eosin, and TUNEL staining assays. Oxygen-glucose deprivation- (OGD-) induced human cardiac myocytes (HCMs) were cultured and transfected. …”
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3091
Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis
Published 2022-01-01“…Both in vivo and in vitro studies have shown that activation of PPARγ leads to reduced expression of the ER stress marker proteins 78-kDa glucose-regulated protein (GRP78), C/EBP homologous protein (CHOP), and Caspase12. …”
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3092
Heart rate variability, a potential assessment tool for identifying anxiety, depression, and sleep disorders in elderly individuals
Published 2025-01-01“…Variables assessed included age, sex, body mass index (BMI), fasting blood glucose, glycated hemoglobin (HbA1c), blood lipids, blood pressure, heart rate, and histories of smoking and alcohol consumption. …”
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3093
Effect of High-Fat Diet on Spatial Learning and Memory and Regulatory Role of N-Methyl-D-Aspartate Receptors in the Dentate Gyrus
Published 2024-12-01“…Newly weaned rats were fed with high-fat diet (HFD) (containing 45% fat) for 12 weeks, and body mass, serum lipid and glucose levels were observed. The Morris water maze (MWM) test was used to evaluate the spatial learning and memory capacity of the rats; Western blot was used to detect the expression of phosphorylated Ca2+/calmodulin dependent protein kinase II (p-CaMKII) and cAMP-response element binding protein (p-CREB), pro-inflammatory cytokines, including interleukin-6 (IL-6) and IL-1β in the hippocampal dentate gyrus (DG); the expression of ionized calcium binding adapter molecule 1 (Iba1) in the DG were observed by Western blot and immunohistochemistry. …”
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3094
Relationship between Body Roundness Index and Risk of Type 2 Diabetes in Japanese Men and Women: A Reanalysis of a Cohort Study
Published 2021-01-01“…After adjusting for age, alcohol intake, smoking status, fatty liver, systolic blood pressure, fasting plasma glucose, glycated hemoglobin, high-density lipoprotein cholesterol, triglycerides, and total cholesterol, the relationship between BRI and T2DM was linear in women (HR (95% CI) for BRI Z score = 1.48 (1.26,1.74)) and curvilinear in men (HR (95% CI) on the left and right of the inflection point = 0.70 (0.44, 1.10) and 1.46 (1.27, 1.67), respectively). …”
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3095
Astragaloside IV alleviates GDM via regulating gut microbiota and gut microbiota metabolomic
Published 2025-01-01“…The measurements of relevant indicators pertaining to GDM symptoms and reproductive outcomes, along with the 16S rRNA sequencing data and LC-MS-based metabolomic profiles, were assessed across all groups.ResultsAfter the 25-day intervention, the GDM model + AS IV group showed significantly decreased fasting blood glucose levels (p = 0.0003), mean insulin levels (p = 0.0001), and insulin resistance index (p = 0.0001). …”
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3096
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization
Published 2025-01-01“…Intervascular BAPs were cultured under flow for up to 3 days and BAPs without internal flow for up to 7 days, showing glucose-responsive insulin secretion quantified through at-line non-disruptive sampling. …”
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3097
Serum Creatinine Level and APACHE-II Score within 24 h of Admission Are Effective for Predicting Persistent Organ Failure in Acute Pancreatitis
Published 2019-01-01“…Serum levels of urea nitrogen (BUN), creatinine, glucose, and hematocrit and APACHE-II score were analyzed for patients with AP. …”
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3098
Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants
Published 2018-01-01“…An important change is a decrease of glucose in the hemicellulosic fraction during dehydration that can reflect a modification of the xyloglucan structure. …”
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3099
Aspects of Growth Hormone and Insulin-Like Growth Factor-I Related to Neuroprotection, Regeneration, and Functional Plasticity in the Adult Brain
Published 2006-01-01“…The functional role of GH and IGF-I in the adult brain will be reviewed with reference to neurotransmitters, glucose metabolism, cerebral blood flow, gap junctional communication, dendritic arborization, exercise, enriched environment, depression, learning, memory, and aging.Briefly, these findings suggest that IGF-I functions as a putative regenerative agent in the adult CNS. …”
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3100
The Effect of Prebiotics, Alone or as Part of Synbiotics, on Cardiometabolic Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized...
Published 2025-01-01“…Results showed high-quality evidence supporting prebiotics’ effects, alone or as part of synbiotics, in reducing body-mass index [<i>n</i> = 853; weighted-mean difference (WMD): −0.510, 95%CI: −0.669, −0.351 kg/m<sup>2</sup>] and diastolic blood pressure (WMD: −2.218, 95%CI: −4.425, −0.010 mmHg), moderate-quality evidence for weight, waist-to-hip ratio, and triglycerides improvements, and low or very-low-quality evidence for waist circumference (WC), fat mass, fasting plasma glucose, fasting insulin, low-density lipoprotein (LDL), total cholesterol (TC), high sensitive-C reactive protein, total testosterone, follicle-stimulating hormone and free androgen index improvements. …”
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