A pilot cross-sectional study of non-communicable diseases in TB household contacts by Y. Hamada, A. Lugendo, T. Ntshiqa, G. Kubeka, J.M. Lalashowi, S. Mwastaula, K. Ntshamane, I. Sabi, S. Wilson, A. Copas, K. Velen, N.E. Ntinginya, L.T. Minja, I. Abubakar, S. Charalambous, M.X. Rangaka

“…We inquired about known NCD and systematically measured blood pressure, and tested for spot blood glucose and haemoglobin A1c. RESULTS: We enrolled 203 adult contacts of 111 persons with TB and 160 controls. …”
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Radioprotective effects of polysaccharides from Poria cocos peels against 60Co-γ induced oxidative damage in vitro and in vivo by Keke Suo, Chaoqiang Zheng, Zhipeng Li, Limin Hao, Jiaqing Zhu, Changcheng Zhao, Yanling Shi, Juanjuan Yi, Jike Lu

“…The results showed that PCPP contained (63.13 ± 3.19)% of total sugar and was composed of mannose, arabinose, glucuronic acid, galacturonic acid, glucose, galactose and fucose in a molar radio of 104.84:1.34:2.83:1.00:290.48:243.30:79.63. …”
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Dietary rosemary oil with/without zymogen forte improves water quality, growth hormones, immune-physiological response, stress resilience, and health status of Chelon ramada grown... by Ashraf I. G. Elhetawy, Mohammed F. El Basuini, Ahmed I. A. Mansour, Shimaa A. Shahin, Amira A. Omar, Mohamed M. Zayed, Mohamed M. Abdel-Rahim

“…Furthermore, significant reductions in the levels of plasma stress indicators (cortisol, creatinine, and glucose) were detected. In addition, there were significant enhancements observed in the levels of innate immune markers, such as white blood cells, total protein, albumin, and immunoglobulin. …”
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Effects of Fermented Soybean Meal Substituting Plant Protein and Fish Meal on Growth, Flesh Quality, and Intestinal Microbiota of Largemouth Bass (Micropterus salmoides) by Beibei Guo, Lingling Huang, Xiaoqin Li, Yunfeng Chen, Tianyu Huang, Lizhou Ma, Xiangjun Leng

“…In serum biochemical indexes, the glucose, total protein, cholesterol and malondialdehyde contents in the three FSM groups, and the triglyceride content in FSM-10-SM and FSM-20 groups were significantly lower than those of FSM-0 group (P<0.05). …”
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Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

“…Our research indicates that all five candidates recommended by AI were able to protect the morphological integrity of RGC cells when exposed to hypoxia and glucose deficiency, and HG9-91-01 showed a higher cell survival rate compared to the other candidates. …”
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Correlation between liver fibrosis in non-alcoholic fatty liver disease and insulin resistance indicators: a cross-sectional study from NHANES 2017–2020 by Bo Yang, Mingsu Gong, Xiaojie Zhu, Yang Luo, Ruiqiu Li, Hai Meng, Yuhan Wang

“…Compared to non-LF patients, LF patients had significantly higher body mass index (BMI), waist circumference (WC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), HbA1c, and fasting blood glucose (FBG) levels (all p &lt; 0.05). Analysis of IR indicators showed that LF patients had significantly higher levels of TyG, TyG-WHtR, TyG-BMI, TyG-WC, TyG-GGT, METS-IR, and HOMA-IR (all p &lt; 0.05). …”
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Epidemiology, clinical spectrum, and outcomes of severe malaria in Eastern Uganda: a prospective study by Cate Namayanja, George Paasi, Jimmy Patrick Alunyo, Denis Amorut, Charles Benard Okalebo, William Okiror, Paul Ongodia, Grace Abongo, Rita Muhindo, Yovani A. M. Lubaale, Peter Olupot-Olupot

“…Laboratory analyses included complete blood counts, lactate, glucose, blood gases, electrolytes, metabolites, and coagulation markers. …”
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Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2 by Huinan Zhang, Xinzhe Du, Tian Gao, Xing Wang, Huifeng Zhang, Manyang Yu, Jing Huang

“…Our findings suggest a notable increase in microglial TRPC1 SUMOylation within both the middle cerebral artery occlusion reperfusion (MCAO/R) model and the in vitro oxygen-glucose deprivation/regeneration model. Mice with a loss of TRPC1 SUMOylation in microglia exhibited improved stroke outcomes including reduced behavior deficits, infarct volume, blood brain barrier damage as well as neuronal apoptosis. …”
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Oridonin ameliorates renal fibrosis in diabetic nephropathy by inhibiting the Wnt/β-catenin signaling pathway by Jushuang Li, Lan Shu, Qianqian Jiang, Baohong Feng, Zhimin Bi, Geli Zhu, Yanxia Zhang, Xiangyou Li, Jun Wu

“…Here, we investigated the mechanism through which Ori affects the Wnt/β-catenin signaling pathway in diabetic rats and human proximal tubular epithelial cells (HK-2) exposed to high glucose (HG) levels. Our results revealed that Ori treatment markedly decreased urinary protein excretion levels, improved renal function and alleviated renal fibrosis in diabetic rats. …”
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Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency by Boonchai Boonyawat, Tim Phetthong, Nithipun Suksumek, Chanchai Traivaree

“…Background. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked inherited erythroenzymopathy in Thailand. …”
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Cryptococcal Meningitis: A Retrospective Cohort of a Brazilian Reference Hospital in the Post-HAART Era of Universal Access by Aline Z. de Azambuja, Gustavo Wissmann Neto, Guilherme Watte, Luciana Antoniolli, Luciano Z. Goldani

“…Multivariate analysis of Cox regression identified headache at presentation, mechanical ventilation, CSF glucose <20 mg/dL, and CSF cryptococcal antigen ≥1 : 1000 for independent risk factors for death. …”
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Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents by Amilton Dos Santos-Júnior, Taciane Barbosa Henriques, Maricilda Palandi de Mello, Osmar Henrique Della Torre, Lúcia Arisaka Paes, Adriana Perez Ferreira-Neto, Letícia Esposito Sewaybricker, Thiago Salum Fontana, Eloisa Helena Rubello Valler Celeri, Gil Guerra-Júnior, Paulo Dalgalarrondo

“…Samples from 120 risperidone users (8–20 years old) were collected and SNPs were analyzed, alongside assessment of chronological and bone ages, prescribed and weight-adjusted doses, use of other psychotropic drugs, waist circumference, BMI z-scores, blood pressure, HOMA-IR index, fasting levels of serum glucose, insulin, cholesterol, triglycerides, transaminases, and leptin. …”
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The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study by Frank L J Visseren, Yolanda van der Graaf, Wilko Spiering, Remy H H Bemelmans, Paulus P Blommaert, Annemarie M J Wassink, Blai Coll

“…Subjects using lipid-lowering medication were excluded.Intervention Participants walked 281±10 km of the classical route to Santiago de Compostela in 12 days in 2009.Primary and secondary outcome measures Walking speed was recorded and blood pressure, weight, waist circumference, lipids and glucose were measured every other day. Changes in risk factors were compared between gender-pooled groups with faster and slower walking speed. …”
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Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

“…Objective To evaluate the effectiveness and safety of metformin use in clinical practice in a large sample of pharmacologically treated patients with type 2 diabetes and different levels of renal function.Design Observational study between July 2004 and December 2010, mean follow-up 3.9 years.Setting Hospital outpatient clinics and primary care in Sweden.Participants 51 675 men and women with type 2 diabetes, registered in the Swedish National Diabetes Register, and on continuous glucose-lowering treatment with oral hypoglycaemic agents (OHAs) or insulin.Main outcome measures Risks of cardiovascular disease (CVD), all-cause mortality and acidosis/serious infection, associated with each treatment regimens, were analysed in all patients and in subgroups with different estimated glomerular filtration rate (eGFR) intervals. …”
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Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States by Qu Zhang, Yemei Wu, Bo Luo

“…Increased OBS was linked to decreases in waist circumference (WC) (OR 0.41; 95% CI: 0.30–0.51; p &lt; 0.0001), triglycerides (TG) (OR 0.71; 95% CI: 0.53–0.92; p = 0.0139), blood pressure (BP) (OR 0.53; 95% CI: 0.40–0.69; p &lt; 0.0001), and fasting glucose (FG) (OR 0.61; 95% CI: 0.45–0.81; p &lt; 0.0001), while HDL-C increased (OR 0.68; 95% CI: 0.51–0.90; p = 0.0065). …”
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The Usage of Lion’s Mane in Sports and Its Metabolic Impact – a literature review by Karolina Stankevič, Kamila Fuczyło, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Justyna Woźniak, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński

“…Results The literature indicates that lion’s mane has potential benefits in enhancing cognitive function, reducing oxidative stress, and improving glucose metabolism—all of which are relevant to sports performance and recovery. …”
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TG : HDL-C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance by Ahmad Kamil Nur Zati Iwani, Muhammad Yazid Jalaludin, Ruziana Mona Wan Mohd Zin, Md Zain Fuziah, Janet Yeow Hua Hong, Yahya Abqariyah, Abdul Halim Mokhtar, Wan Nazaimoon Wan Mohamud

“…Children with elevated TG : HDL-C ratio had lower fasting glucose compared to children with MetS (boys = 5.15 ± 0.4 vs. 6.34 ± 2.85 mmol/l, p=0.02; girls = 5.17 ± 0.28 vs. 6.8 ± 4.3 mmol/l, p=0.03). …”
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Maternal and Fetal Lipid and Adipokine Profiles and Their Association with Obesity by Mario Solis-Paredes, Salvador Espino y Sosa, Guadalupe Estrada-Gutierrez, Sonia Nava-Salazar, Veronica Ortega-Castillo, Mario Rodriguez-Bosch, Eyerahi Bravo-Flores, Aurora Espejel-Nuñez, Maricruz Tolentino-Dolores, Rubí Gaona-Estudillo, Nancy Martinez-Bautista, Otilia Perichart-Perera

“…Healthy pregnant women at term who delivered by C-section were enrolled. Maternal and fetal glucose, lipid profile, adiponectin, leptin, and resistin levels were analyzed by obesity and maternal weight gain. …”
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Efficacy and safety of glucagon-like peptide-1 receptor agonists in the elderly versus non-elderly patients with type 2 diabetes mellitus: insights from a systematic review by Yao Wang, Jiangling Wang, Qian Gong, Haoming Wu, Shuhao Yang, Jufeng He, Xulin Hu, Tianfang Huang

“…In conclusion, while certain AEs leading to discontinuation may be more prevalent in older patients, GLP-1RAs are effective for weight loss and lead to decreased glucose concentrations with a low rate of complications in elderly patients.…”
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TREM2 affects DAM-like cell transformation in the acute phase of TBI in mice by regulating microglial glycolysis by Lin Wang, Diqing Ouyang, Lin Li, Yunchuan Cao, Yingwen Wang, Nina Gu, Zhaosi Zhang, Zhao Li, Shuang Tang, Hui Tang, Yuan Zhang, Xiaochuan Sun, Jin Yan

“…Various techniques were used to assess the role of DAM-like cells in TBI and the effects of glycolysis on DAM-like cells, including RT‒qPCR, immunofluorescence assays, behavioural tests, extracellular acidification rate (ECAR) tests, Western blot analysis, cell magnetic sorting and culture, glucose and lactate assays, and flow cytometry. Results DAM-like cells were observed in the acute phase of TBI in mice, and their transformation depended on TREM2 expression. …”
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