Correlation between OSAHS and Early Peripheral Atherosclerosis Indices in Patients with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study by Xin Zhao, Xiaofeng Yu, Sixu Xin, Wei Zhang, Xiaomei Zhang, Linong Ji

“…Results. (1) As the degree of OSAHS increased, ABI decreased gradually and was lower than that in the control group, but PWV increased and was higher than that in the control group (p<0.05, respectively). (2) The apnea-hypopnea index (AHI) positively correlated with PWV (r=0.36, p<0.05) and negatively correlated with ABI (r=−0.37, p<0.05). (3) Multivariate logistic regression showed that after adjusting for age, gender, duration, BMI, blood pressure, blood glucose, blood lipid, and other factors, OSAHS was a risk factor of lower extremity arterial disease (LEAD) in patients with T2DM. …”
Get full text

Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice by Sorim Choung, Kyong Hye Joung, Bo Ram You, Sang Ki Park, Hyun Jin Kim, Bon Jeong Ku

“…Lobeglitazone treatment for 4 weeks in high fat diet- (HFD-) induced obese mice (HL group) improved insulin resistance and glucose intolerance compared to HFD-induced obese mice (HU group). …”
Get full text

Non-pharmacological Methods Used in the Management of Type 2 Diabetes Mellitus by a Selected Group of People with T2DM in Colombo District, Sri Lanka: A Mixed-Method Study by Lakshani Herath, Manisha Kamalsiri, Perananthan Inthuja, Gayani P Gamage, Dinithi Vidanage

“…Diet control, exercise, stress management, and adding glucose-lowering food have been identified as the main non-pharmacological methods practiced. …”
Get full text

The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

“…One hundred Uyghur subjects where divided into two groups, T2DM and nonimpaired glucose tolerance (NGT) groups. DNA methylation of FOSL2 was also analyzed by MassARRAY Spectrometry and methylation data of individual units were generated by the EpiTyper v1.0.5 software. …”
Get full text

Application Value of NT-proBNP Combined with NLR in Evaluation of Major Adverse Cardiac Events in Elderly Patients with Chronic Heart Failure by Zhiyong Li, Hui Rong, Wenxun Wu, Ting Huang, Jun Xu

“…The age, WBC, NEU, LYM, PLT, blood glucose, NLR, and NT-proBNP of MACE group and non-MACE group were significantly different (P<0.05). …”
Get full text

Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy by Hui Wang, Haojun Shi, Jing Zhang, Guoliang Wang, Jinxiang Zhang, Fagang Jiang, Qing Xiao

“…TLR4 mutation did not block the occurrence of high blood glucose after STZ injection compared with WT mice but did alleviate the progression of DR and alter the expression of the small vessel proliferation-related genes, vascular endothelial growth factor (VEGF), and hypoxia inducible factor-1α (HIF-1α). …”
Get full text

The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…CC037 line exhibited a substantial increase in body weight on HFD, whereas line CC005 exhibited differing responses based on sex. Glucose tolerance tests revealed significant variations, with some lines like CC005 showing a marked increase in area under the curve (AUC) values on HFD. …”
Get full text

Evaluation of antidiabetic potential, cardio, pancreatic, nephroprotective effect, and herb-herb-drug interaction of Madhukiran formulations in T2 diabetic rats by Vrushabh S. Kondalkar, Pranali P. Polshettiwar, Ganesh B. Choudhari, Anil T. Pawar, Vishnu P. Choudhari

“…Results and conclusion: MFs alone, concomitantly, and with ME combination significantly decreased elevated plasma glucose level, urine volume, and urinating frequency. …”
Get full text

Impact of sleep chronotype on blood pressure and metabolic markers by Weiwei Huang, Qinglu Wang, Yuan Gao, Jiefeng Wang, Feihao Wang, Jiyou Tang

“…Blood pressure was recorded, and fasting venous blood samples were collected to assess liver function, renal function, blood glucose levels, blood lipid profile, and other biochemical parameters.Results1. …”
Get full text

PTPIP51: A New Interaction Partner of the Insulin Receptor and PKA in Adipose Tissue by M. A. Bobrich, S. A. Schwabe, A. Brobeil, M. Viard, M. Kamm, F. C. Mooren, K. Krüger, C. Tag, M. Wimmer

“…After ten weeks, we measured glucose tolerance of the mice. Adipose tissue samples were analyzed by immunofluorescence and Duolink proximity ligation assay to quantify interactions of PTPIP51 with either insulin receptor (IR) or PKA. …”
Get full text

SIRT1/PGC-1α-mediated mitophagy participates the improvement roles of BMAL1 in podocytes injury in diabetic nephropathy: evidences from in vitro experiments by Yanxia Rui, Yinfeng Guo, Linying He, Min-er Wang, Henglan Wu

“…Materials and methods High D-glucose (HG)-treated MPC5 cells was used as a podocyte injury model for investigating the potential roles of BMAL1 in DN. …”
Get full text

Biochemical characteristics, nutrient intakes, and chronic disease risk according to the dietary fat energy ratio in middle-aged Korean: a cross-sectional study using data from the... by Ga-Hyeon Jeong, Sook-Bae Kim

“…Biochemical characteristics in the insufficient group exhibited the lowest levels for fasting blood glucose, hemoglobin A1c, and triglycerides. Significant differences were found in both the quantitative and qualitative intake of nutrients. …”
Get full text

Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD) by Tomasz Sawczyn, Dominika Stygar, Katarzyna Nabrdalik, Michał Kukla, Oliwia Masri, Łukasz Magrowski, Wojciech Karcz, Jerzy Jochem

“…Metabolic surgery procedures are designed not only for sustained weight loss but also for achieving positive metabolic changes, including improved glucose tolerance and insulin sensitivity, along with an increase in energy expenditure. …”
Get full text

CONDITION OF HORMONAL STATUS OF THE BODY IN WHITE RATS UNDER THE EXPOSURE TO SODIUM FLUORIDE by I.Yu. Bagmut, I.L. Kolisnyk, S.I. Kryzhna, A.V. Titkova, L.Yu. Svyrydenko

“…The results showed reduced levels of folliculotropin and progesterone, increased levels of thyroxine, adrenocorticotropin, glucagon, triiodothyronine, thyrotropin and calcitonin, while insulin, somatostatin and serum glucose levels decreased. There was no change in the dynamics of the content of sex hormones - luteotropin, prolactin, testosterone compared with the control (P> 0.05). …”
Get full text

Adverse effects of GLP – 1 Receptor Agonists by Anna Kasprzak, Monika Kułaga, Monika Grzybek, Diana Mazur-Lesińska, Barbara Szostak, Sylwia Wielgosz-Biała, Krzysztof Tyszkiewicz, Borys Łozowski, Małgorzata Kasprzak, Barbara Wilczyńska

“… Introduction and purpose Glucagon-like peptide-1 receptor agonists (GLP – 1 RAs) are indicated in type 2 diabetes (T2D) and obesity because of their high efficacy in controlling blood glucose levels and inducing weight loss. Patients may develop gastrointestinal adverse effects (GI AEs) such as nausea, vomiting, diarrhoea, constipation and, less commonly, pancreatitis and cholelithiasis. …”
Get full text

Investigation of Crinum solapurense leaves extract for antidiabetic activity and histopathological evaluation in an in-vivo experimental model by Sunayana Mali, Gaurav Jain, Jyotiram Sawale, Audumbar Mali

“…The C. solapurense leaf extracts significantly reduced blood glucose levels (BGL) in dexamethasone-induced male albino Wistar rats. …”
Get full text

Experiences of adults with type 2 diabetes mellitus with low socioeconomic status: a qualitative study by Vahide Semerci Çakmak, Ebru Sönmez Sari, Serap Çetinkaya Özdemir

“…According to Theme 3, it was observed that the participants faced difficulties related to diabetes self-management, including blood glucose monitoring, insulin injection administration, and maintaining glycemic control.” …”
Get full text

Digestive Fermentation, Antioxidant Status, and Haemato-Biochemical Indices of Growing Rabbits Fed on Diets Supplemented with Ziziphus spina-christi Leaf by Suha Hashim Abduljawad

“…These observations of total protein and albumin within the range of reference values were reported in healthy rabbits, while glucose significantly decreased with the addition of ZL and AST in the blood increased significantly. …”
Get full text

Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care by Simone Foti Randazzese, Mariarosaria La Rocca, Bruno Bombaci, Alessandra Di Pisa, Elèna Giliberto, Teresa Inturri, Daniel Militi, Fortunato Lombardo, Eloisa Gitto, Giuseppina Salzano, Stefano Passanisi

“…Pathogenesis is linked to insulin deficiency and an excess of counter-regulatory hormones, which disrupt glucose, protein, and lipid metabolism, causing hyperglycemia, ketosis, acidosis, dehydration, and electrolyte imbalances. …”
Get full text

Efficacy of Hot Tea Infusion vs. Ethanolic Extract of Moringa oleifera for the Simultaneous Treatment of Nonalcoholic Fatty Liver, Hyperlipidemia, and Hyperglycemia in a Murine Mod... by Salma I. Cortes-Alvarez, Ivan Delgado-Enciso, Alejandrina Rodriguez-Hernandez, Gustavo A. Hernandez-Fuentes, Nomely S. Aurelien-Cabezas, Norma A. Moy-Lopez, Nadia Y. Cortes-Alvarez, Jorge Guzman-Muñiz, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Karen A. Mokay-Ramirez, Carlos E. Barajas-Saucedo, Carmen A. Sanchez-Ramirez

“…A significant reduction of SGPT, SGOT, lipids, urea, and glucose in blood among NAFLD groups treated with MO (infusion or extract) was found, when compared to the NAFLD-placebo group. …”
Get full text