Carrageenan-Induced Colonic Inflammation Is Reduced in Bcl10 Null Mice and Increased in IL-10-Deficient Mice by Sumit Bhattacharyya, Liquan Xue, Suzanne Devkota, Eugene Chang, Stephan Morris, Joanne K. Tobacman

“…Exposure to low concentrations of carrageenan (10 μg/mL in the water supply) has produced glucose intolerance, insulin resistance, and impaired insulin signaling in C57BL/6 mice. …”
Get full text

Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK–IDH2 pathway by Hao Huang, Shuai Guo, Ya‐Qin Chen, Yu‐Xing Liu, Jie‐Yuan Jin, Yun Liang, Liang‐Liang Fan, Rong Xiang

“…Mechanistically, RTN3 regulated these events through its interactions with glucose‐regulated protein 78 (GRP78), which further inhibited the adenosine 5 monophosphate‐activated protein kinase (AMPK)–isocitrate dehydrogenase 2 (IDH2) pathway. …”
Get full text

Influence of Dapagliflozin on Glycemic Variations in Patients with Newly Diagnosed Type 2 Diabetes Mellitus by Feng-fei Li, Gu Gao, Qian Li, Hong-hong Zhu, Xiao-fei Su, Jin-dan Wu, Lei Ye, Jian-hua Ma

“…Compared with control group, patients in dapagliflozin group exhibited reduction in 24-hour MBG (P=0.026) and lower mean plasma glucose concentrations, especially during periods from 2400 to 0200 and 1300 to 1800 (P<0.05, resp.). …”
Get full text

Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats by Lukáš Alán, Tomáš Olejár, Monika Cahová, Jaroslav Zelenka, Zuzana Berková, Magdalena Smětáková, František Saudek, Radoslav Matěj, Petr Ježek

“…With maturation and aging of GK rats, disturbed cytoarchitecture occurred with irregular beta cells accompanied by delta cell hyperplasia and loss of pancreatic polypeptide (PPY) positivity. Unlike the constant glucose-stimulation index for insulin PI release in Wistar rats, this index declined with GK age, whereas for somatostatin it increased with age. …”
Get full text

Study of Body Composition and Metabolic Parameters in HIV-1 Male Patients by Gurudath Gundurao Sreekantamurthy, N Biplab Singh, Th Bhimo Singh, Th Suraj Singh, Karam Romeo Singh

“…Fasting and postprandial hyperglycaemia was found PIs and impaired glucose tolerance in stavudine regimen. Conclusion. …”
Get full text

Comparative Abilities of Body Mass Index, Waist Circumference, Abdominal Volume Index, Body Adiposity Index, and Conicity Index as Predictive Screening Tools for Metabolic Syndrome... by Lawrence Quaye, William Kwame Boakye Ansah Owiredu, Nafiu Amidu, Peter Paul Mwinsanga Dapare, Yussif Adams

“…Blood samples were collected for fasting blood glucose (FBG) and lipid profile. MetS was classified using the harmonised criteria as indicated by the joint interim statement (JIS). …”
Get full text

Positive real-time PCR in pneumococcal meningitis 12 hours after initiation of antibiotic therapy – case report by Cem Thunstedt, Carla Palleis, Johannes Wischmann, Suzette Heck, Konstantinos Dimitriadis, Matthias Klein

“…Lumbar puncture revealed cloudy cerebrospinal fluid with elevated cell count, protein, and low glucose. While blood and CSF cultures remained negative, multiplex PCR for Streptococcus pneumoniae was positive even 10 h after beginning of effective antibiotic therapy. …”
Get full text

Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases by Karama Bouchaala, Mabrouk Bahloul, Sabrine Bradii, Hela Kallel, Kamilia Chtara, Mounir Bouaziz

“…Laboratory samples showed high serum glucose levels. They had metabolic acidosis with elevated anion gap. …”
Get full text

The Effect of Preoperative Type 2 Diabetes and Physical Fitness on Mental Health and Health-Related Quality of Life after Roux-en-Y Gastric Bypass by Cathrine L. Wimmelmann, Michael T. Lund, Merethe Hansen, Flemming Dela, Erik L. Mortensen

“…Measures included oral and intravenous glucose tolerance tests, VO2max test, Symptoms Checklist (SCL-90), Short Form Health Survey 36 (SF-36), Body Image Questionnaire, and a questionnaire assessing sociodemographic factors and medical status. …”
Get full text

Phenolic Profile, Sugar Composition, and Antioxidant Capacities of Some Common Date Palm (Phoenix dactylifera L.) Cultivars as a Potential Nutraceutical and Functional Food Ingredi... by Imen Bettaieb, Ahlem Kilani, Khadija Ben Othman, Mohamed Ali Benabderrahim, Walid Elfalleh

“…Contrary to the Deglet Nour variety, the six common dates contain a high amount of fructose and glucose (reducing sugars) and a low content of sucrose. …”
Get full text

Chemical test and cellular bioactivities and flavor enhancer properties of mung bean protein via glycation reaction by Srisukpachin Nuttakarn, Tabtimmai Lueacha, Sedtananun Saranya, Laohakunjit Natta, Sonklin Chanikan

“…Therefore, this research study and development of flavor-enhancers derived from the mung bean meal protein isolated (MPI) reacted with reducing sugars as glucose (Glu) for generating Maillard reaction products (MRPs) under thermal process. …”
Get full text

Minimum Description Length and Multi-Criteria Decision Analysis in Predictive Modeling by Petr Silhavy, Katerina Hlavackova-Schindler, Radek Silhavy

“…Four datasets from diverse domains, including software engineering (effort estimation), healthcare (glucose level prediction), finance (GDP prediction), and stock market prediction, were used to validate the framework. …”
Get full text

Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells by Sang Soo Kim, Hee Joo Cho, Jung Yoon Kang, Hee Kyu Kang, Tag Keun Yoo

“…We compared expressions of AR, heat shock protein 27 (HSP27), clusterin (CLU), glucose-related protein 78 (GRP78), and cellular FLICE-like inhibitory protein (c-FLIP) and their genes between es-LNCaP (less than 33 times subcultured, L-33), ls-LNCaP (over 81 times subcultured, H-81), and si-LNCaP (AR siRNA transfected ls-LNCaP) by Western blotting and RT-PCR. …”
Get full text

Myocardial Perfusion and Function Are Distinctly Altered by Sevoflurane Anesthesia in Diet-Induced Prediabetic Rats by Charissa E. van den Brom, Chantal A. Boly, Carolien S. E. Bulte, Rob F. P. van den Akker, Rick F. J. Kwekkeboom, Stephan A. Loer, Christa Boer, R. Arthur Bouwman

“…WD-feeding resulted in a prediabetic phenotype characterized by obesity, hyperinsulinemia, hyperlipidemia, glucose intolerance, and hyperglycemia. At baseline, WD-feeding impaired myocardial perfusion and systolic function compared to CD-feeding. …”
Get full text

When to Consider a Diagnosis of Maturity-Onset Diabetes of the Young: Precise Diagnosis Leads to Better Management and Quality of Life for the Patients by Yujia Gao, Kalyan Mansukhbhai Shekhda, Sarah N. Ali

“…A 33-year-old South Asian lady was referred to a diabetes clinic for suspected T2DM due to strong family history of T2DM, ethnicity, and persistently elevated fasting blood glucose levels. Her genetic testing confirmed GCK-MODY (Glucokinae-maturity-onset diabetes of the young). …”
Get full text

A Fast and Validated HPLC Method for Simultaneous Determination of Dopamine, Dobutamine, Phentolamine, Furosemide, and Aminophylline in Infusion Samples and Injection Formulations by Fuchao Chen, Baoxia Fang, Sicen Wang

“…The results of the stability study showed that mixtures of DPM, DBM, PTM, FSM, and APL in 5% glucose or 0.9% sodium chloride injection were stable for 48 hours when stored in polypropylene syringes at 25°C.…”
Get full text

Hepatocytic Differentiation Potential of Human Fetal Liver Mesenchymal Stem Cells: In Vitro and In Vivo Evaluation by Hoda El-Kehdy, Guillaume Pourcher, Wenwei Zhang, Zahia Hamidouche, Sylvie Goulinet-Mainot, Etienne Sokal, Pierre Charbord, Mustapha Najimi, Anne Dubart-Kupperschmitt

“…FL-MSCs differentiated in this way displayed significant features of hepatocyte-like cells as demonstrated in vitro by the upregulated expression of specific hepatocytic markers and the induction of metabolic functions including CYP3A4 activity, indocyanine green uptake/release, and glucose 6-phosphatase activity. Following transplantation, naive and differentiated FL-MSC were engrafted into the hepatic parenchyma of newborn immunodeficient mice and differentiated in situ. …”
Get full text

Total Antioxidant Status in Type 2 Diabetic Patients in Palestine by Akram T. Kharroubi, Hisham M. Darwish, Mutaz A. Akkawi, Abdelkareem A. Ashareef, Zaher A. Almasri, Khaldoun A. Bader, Umaiyeh M. Khammash

“…Mean TAS levels were similarly higher in subjects with high fasting plasma glucose (FPG) compared to normal FPG (2.19 versus 1.90 mM Trolox) and high HbA1c (≥6.5%) compared to HbA1c < 6.5% (2.14 versus 1.91 mM Trolox). …”
Get full text

Physician Perceptions of the Safety and Efficacy of GLP-1 Receptor Agonists: Underestimation of Cardiovascular Risk Reduction and Discrepancies with Clinical Evidence by Srikanth Krishnan, Pratyaksh K. Srivastava, Jayram Attaluri, Rebecca Nayeri, Dhananjay Chatterjee, Jay Patel, Ali Nsair, Matthew Budoff, Arash Nayeri

“…Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonists (GIP/GLP-1 RAs) are emerging as effective treatments for obesity and cardiometabolic disease. …”
Get full text

Hyperlactatemia and the Outcome of Type 2 Diabetic Patients Suffering Acute Myocardial Infarction by Jovanovic Aleksandar, Peric Vladan, Snezana Markovic-Jovanovic, Radojica Stolic, Jadranka Mitic, Tanja Smilic

“…Conclusion. Both defective glucose metabolism and low tissue oxygenation may contribute to the lactate production in diabetic patients with acute myocardial infarction; high lactate levels indicate increased risk for poor outcome in this population comparing to nondiabetic patients. …”
Get full text