SGLT2i and GLP-1RA in Cardiometabolic and Renal Diseases: From Glycemic Control to Adipose Tissue Inflammation and Senescence by Luis D'Marco, Valery Morillo, José Luis Gorriz, María K. Suarez, Manuel Nava, Ángel Ortega, Heliana Parra, Nelson Villasmil, Joselyn Rojas-Quintero, Valmore Bermúdez

“…Over the last few years, the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP-1RA) has increased substantially in medical practice due to their documented benefits in cardiorenal and metabolic health. …”
Get full text

Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion by Katsuya Sakimura, Tatsuya Maekawa, Shin-ichi Kume, Takeshi Ohta

“…In the present study, we investigated the circadian rhythms of spontaneous locomotor activity, metabolic parameters (plasma glucose, triglyceride, and total cholesterol), and plasma melatonin concentrations in Spontaneously Diabetic Torii (SDT) fatty rats, a novel animal model of type 2 DM. …”
Get full text

Nutritional Quality, Potential Health Promoting Properties and Sensory Perception of an Improved Gluten Free Bread Formulation Containing Inulin, Rice Protein and Bioactive Compoun... by Alessandro Guglielmetti, Beatriz Fernandez-Gomez, Giuseppe Zeppa, Dolores del Castillo

“…The observed health-promoting properties suggest that coffee by-product extracts could potentially be used as functional food ingredients or supplements to reduce the risk of chronic diseases associated with oxidative stress and to control postprandial glucose levels. Based on consumers’ preferences, we obtained new bread formulations with high nutritional and sensorial quality, suitable for celiacs and with the potential to reduce the risk of gastrointestinal disease related to oxidative stress. …”
Get full text

The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse by Yael Oppenheim, Grace Kim, Yoshiyuki Ban, Pamela Unger, Erlinda Concepcion, Takao Ando, Yaron Tomer

“…Their thyroids were examined for histology and blood was tested for antithyroglobulin antibody levels. T4 and glucose levels were also assessed. In the IFN-injected group, 6/13 (46.2%) developed thyroiditis and/or thyroid antibodies while in the saline-injected group, only 4/13 (30.8%) developed thyroiditis and/or thyroid antibodies (p=0.4). …”
Get full text

The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity by Zhiwei Wang, Shaying Yang, Liangju Liu, Aiqin Mao, Hao Kan, Fan Yu, Xin Ma, Lei Feng, Tingting Zhou

“…IPA or Clostridium sporogenes supplement effectively controls weight gain, improves glucose metabolism, and reduces inflammation in DIO mice. …”
Get full text

Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia by Jodi Woan-Fei Law, Vengadesh Letchumanan, Kar-Wai Hong, Sunny Hei Wong, Nurul Syakima Ab Mutalib, Ya-Wen He, Kok-Gan Chan, Loh Teng-Hern Tan

“…Analysis of whole-cell sugars revealed the presence of glucose, ribose and mannose. The polar lipid profile of the strain comprised lipid, glycolipid, phospholipid, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, phosphoglycolipid, and diphosphatidylglycerol. …”
Get full text

Study on the Correlation of Skin Advanced Glycation End Products With Diabetic Cardiovascular Autonomic Neuropathy by Fang Y, Dai W, Cao Y

“…The clinical features of the two groups were analyzed; the factors affecting DCAN were analyzed by multiple logistic regression analysis, and those related to skin AGE accumulation in patients with DCAN were analyzed by Spearman correlation analysis and Pearson correlation analysis.Results: Compared with the No_DCAN group, the combined DR ratio, fasting plasma glucose (FPG), and skin AGEs were increased in the DCAN group (all P< 0.05). …”
Get full text

Switched CMOS current source compared to enhanced Howland circuit for bio-impedance applications by da Silva Pablo Dutra, Filho Pedro Bertemes

“…Bio-impedance Spectroscopy (BIS) is a technique that allows tissue analysis to diagnose a variety of diseases, such as medical imaging, cancer diagnosis, muscle fatigue detection, glucose measurement, and others under research. The development of CMOS integrated circuit front-ends for bioimpedance analysis is required by the increasing use of wearable devices in the healthcare field, as they offer key features for battery-powered wearable devices. …”
Get full text

Biomimic models for in vitro glycemic index: Scope of sensor integration and artificial intelligence by Mohammed Salman C K, Muskan Beura, Archana Singh, Anil Dahuja, Vinayak B. Kamble, Rajendra P. Shukla, Sijo Joseph Thandapilly, Veda Krishnan

“…Non-enzymatic sensors offer superior stability and repeatability in complex matrices, enabling real-time glucose quantification across multiple timepoints without enzyme degradation constraints. …”
Get full text

MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke by Xiaoqing Ma, Ho Jun Yun, Kenneth Elkin, Yunliang Guo, Yuchuan Ding, Guangwen Li

“…Additionally, hCMEC/D3 cells were subjected to oxygen–glucose deprivation (OGD) and cocultured with HL-60 cells. …”
Get full text

Increased distribution of carbon metabolic flux during de novo cytidine biosynthesis via attenuation of the acetic acid metabolism pathway in Escherichia coli by Tong Ye, Wei Ding, Zhengxu An, Haojie Zhang, Xiaobo Wei, Junnan Xu, Huiyan Liu, Haitian Fang

“…Disruption of the poxB and pta genes resulted in reduced acetic acid production and glucose consumption. Transcriptomic and metabolomic analyses revealed that impairing the acetic acid metabolic pathway in E. coli effectively redirected carbon flux toward cytidine biosynthesis, yielding a 5.26-fold reduction in acetate metabolism and an 11.56-fold increase in cytidine production. …”
Get full text

Appetite Response among Those Susceptible or Resistant to Obesity by Rachel C. Brown, Rebecca T. McLay-Cooke, Sara L. Richardson, Sheila M. Williams, David R. Grattan, Alexandra W.-A. H. Chisholm

“…Fingerprick blood samples to measure ghrelin, total peptide YY (PYY), leptin, glucose, and insulin along with appetite ratings were collected at baseline and 15, 30, 60, 120, and 180 min following consumption of a standardized meal. …”
Get full text

Diabetes self-management education interventions in the WHO African Region: A scoping review. by Emmanuel Kumah, Godfred Otchere, Samuel Egyakwa Ankomah, Adam Fusheini, Collins Kokuro, Kofi Aduo-Adjei, Joseph A Amankwah

“…While the majority yielded significant positive results on HbA1c, diabetes knowledge, blood pressure, blood sugar and foot care practices; few demonstrated positive outcomes on self-efficacy, BMI, physical activity; self-monitoring of blood glucose, medication adherence, smoking and alcohol consumption.…”
Get full text

Рerioperative period of high-risk patients with coronary artery disease by O.K. Gogayeva

“…Among comorbid conditions, type 2 diabetes mellitus was diagnosed in 50 (25.7 %) patients, impaired glucose tolerance – in 82 (42.2 %) patients, obesity – in 74 (38.1 %) patients, 86 (44.3 %) patients were overweight with a body mass index 25–29.9 kg/m2, and 75 (38.6 %) patients were diagnosed with chronic kidney disease. …”
Get full text

Systemic Factors Associated with Treatment Response in Diabetic Macular Edema by Wendy Meihua Wong, Caroline Chee, Mayuri Bhargava, Charmaine Chai, Hazel Lin, Paul Zhao, Erlangga Ariadarma Mangunkusumo, Thet Naing, Yew Sen Yuen, Tien Yin Wong, Xinyi Su, Gopal Lingam

“…Patients with high levels of HbA1c and poor response to anti-VEGF may benefit from strict control of their blood glucose.…”
Get full text

Effects of age and diet on triglyceride metabolism in mice by Kathryn M. Spitler, Shwetha K. Shetty, Brandon S.J. Davies

“…We measured survival, body composition, plasma triglyceride levels, chylomicron clearance, and oral fat, glucose, and insulin tolerance. Triglyceride levels in mice did not increase with age, regardless of diet. …”
Get full text

Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors by Xiaoyan Sheng, Yuebo Zhang, Zhenwei Gong, Cheng Huang, Ying Qin Zang

“…Cinnamon, a widely used spice in food preparation and traditional antidiabetic remedy, is found to activate PPARγ and α, resulting in improved insulin resistance, reduced fasted glucose, FFA, LDL-c, and AST levels in high-caloric diet-induced obesity (DIO) and db/db mice in its water extract form. …”
Get full text

Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas by Arjen H. G. Cleven, Manon van Engeland, Bradly G. Wouters, Adriaan P. de Bruïne

“…We studied the role of protein expression of hypoxia-inducible factor (HIF)-1α, HIF-2α, carbonic anhydrase 9 (CA9) and glucose transporter 1 (GLUT1) in patients with colorectal adenocarcinomas. …”
Get full text

Prevalence of Metabolic Syndrome One Year after Delivery in Finnish Women at Increased Risk for Gestational Diabetes Mellitus during Pregnancy by Jatta Puhkala, Tarja I. Kinnunen, Tommi Vasankari, Katriina Kukkonen-Harjula, Jani Raitanen, Riitta Luoto

“…Twenty-seven percent had elevated fasting plasma glucose (≥5.6 mmol/L), and 29% had reduced HDL cholesterol (≤1.3 mmol/L). …”
Get full text

The influence of gender and waist circumference in the association of body fat with cardiometabolic diseases by Milad Bagheri, Mehran Nouri, Ali Kohanmoo, Reza Homayounfar, Masoumeh Akhlaghi

“…Results Cardiometabolic risk factors (body mass index, waist circumference, blood pressure, blood glucose and lipids) had an inverse association with BF% tertiles in both sexes. …”
Get full text