Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design by Kizito Kayumba, Corneille Ntihabose, Sabine Musange Furere, Bernard Ngabo, Piero Irakiza, Felix K. Rubuga, Nathalie Umutoni, Ina Rukundo Kalisa, Pascal Birindabagabo, Emile Rwamasirabo, Emmanuel Kayibanda, Patience Mukundirukuri, Gashaija Absolomon, Sumana Dhanani, Jeanine Condo

“…Abstract Background Despite the high demand for public services globally, ensuring the quality of services provided by public health facilities is challenging. …”
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Estimation des rendements fourragers des pâturages dans les espaces climatiques du Burkina Faso à partir de données satellitaires by Wièmè Some, Antoine Denis, Amani Louis Kouadio, Bakary Djaby, Hassan Bismark Nacro, Adrien Marie Gaston Belem, Bernard Tychon

“…Les variables agroclimatiques se sont révélées inutiles, et celles issues du FAPAR sont globalement plus performantes que celles issues du NDVI. …”
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Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet by Lakshmi Arivazhagan, Sofie Delbare, Robin A. Wilson, Michaele B. Manigrasso, Boyan Zhou, Henry H. Ruiz, Kaamashri Mangar, Ryoko Higa, Emily Brown, Huilin Li, Michael J. Garabedian, Ravichandran Ramasamy, Kathryn J. Moore, Edward A. Fisher, Neil D. Theise, Ann Marie Schmidt

“…Background & Aims: Metabolic syndrome-associated steatotic liver disease (MASLD) and metabolic syndrome-associated steatohepatitis (MASH) have global prevalence rates exceeding 25% and 3-6%, respectively. …”
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Integrating network analysis and experimental validation to reveal the mechanism of Cuscuta chinensis lam. Extract in the treatment of IgA nephropathy by Xianlong Zhang, Mingjie Liang, Ziyang Lin, Minyi Li, Tingting Duan, Yun Han, Lanqing Meng, Mengqiu Li, Guixuan Lin, Tao Xia, Ying Lai, Boen Liang, Bingqiong Li, Minhua Li, Fengxin Kang, Quan Zhu, Zhenghai Li, Junzheng Yang

“…Purpose/aim: IgA nephropathy represents a prevalent form of the common kidney disease globally, accounting for the majority of cases of chronic kidney disease and renal failure. …”
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Berberine alleviates enterotoxigenic Escherichia coli-induced intestinal mucosal barrier function damage in a piglet model by modulation of the intestinal microbiome by Min Du, Xinran Liu, Xu Ji, Yue Wang, Xiaodan Liu, Chunfang Zhao, Chunfang Zhao, Erhui Jin, Erhui Jin, Youfang Gu, Youfang Gu, Hongyu Wang, Feng Zhang, Feng Zhang

“…This disease can lead to substantial morbidity and mortality and is a major global health concern. Managing ETEC infections is challenging owing to the increasing prevalence of antibiotic resistance. …”
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Climate change policies reduce air pollution and increase physical activity: Benefits, costs, inequalities, and indoor exposures by Sean Beevers, Nosha Assareh, Andrew Beddows, Gregor Stewart, Mike Holland, Daniela Fecht, Yunzhe Liu, Anna Goodman, Heather Walton, Christian Brand, Dimitris Evangelopoulos, Dylan Wood, Tuan Vu, David Dajnak

“…The burden of diseases attributable to air pollution is comparable to those of global health risks such as unhealthy diets and tobacco smoking, with many air pollution sources also emitting climate heating gases. …”
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RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer by Charlotte K. Kindt, Sidse Ehmsen, Sidse Ehmsen, Sidse Ehmsen, Sofie Traynor, Benedetta Policastro, Nikoline Nissen, Mie K. Jakobsen, Monique F. Hundebøl, Lene E. Johansen, Martin Bak, Elsa Arbajian, Johan Staaf, Henrik J. Ditzel, Henrik J. Ditzel, Henrik J. Ditzel, Carla L. Alves

“…RET silencing was evaluated mechanistically using global gene expression and pathway analysis. The clinical relevance of RET expression in ER+ breast cancer was investigated by gene array analysis of primary tumors treated with endocrine therapy and by immunohistochemical scoring of metastatic lesions from patients who received combined CDK4/6i and endocrine therapy.ResultsWe show that RET is upregulated in ER+ breast cancer cell lines resistant to combined CDK4/6i and fulvestrant compared to isogenic cells resistant to fulvestrant alone. siRNA-mediated silence of RET in high RET-expressing, combined CDK4/6i- and fulvestrant-resistant cells reduced their growth partially by affecting cell cycle regulators of the G2-M phase and E2F targets. …”
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The Impact of Acute Aerobic Exercise on General and Food-Related Inhibitory Function Among Young Adults with Obesity: An Event-Related Potential (ERP) Study by Chun Xie, Tao Huang, Yingying Wang, Peisi Wang, Yanxia Chen, Jiali Qian, Guozhuang Chen, Kun Wang

“…<b>Backgrounds and Objectives</b>: Obesity presents a significant global public health challenge and is associated with declines in both general and food-related inhibitory control, crucial for maintaining a healthy weight and preventing obesity progression. …”
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The contextual adaptation and educational impacts of the mhGAP-IG to address child mental and behavioral disorder treatment gap in China: A mixed-method study by Meng Zheng, Yi Zhang, Feng Chen, Ang Chen, Di Kong, Kun Xie, Jie Li, Brian James Hall, Andre M.N. Renzaho, Jian-hui Gao, Dao-meng Cheng, Qing Zou, Xin-yuan Zhong, Qi-mei Yu, Wen Chen

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Spontaneous high clonal expansion of Wilms’ tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms’ tumor gene 1-expressing solid tumor by Soyoko Morimoto, Yukie Tanaka, Jun Nakata, Fumihiro Fujiki, Kana Hasegawa, Hiroko Nakajima, Sumiyuki Nishida, Akihiro Tsuboi, Naoki Hosen, Naoki Kagawa, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoya Hashimoto, Toshiki Yoshimine, Atsushi Kumanogoh, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama

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A CO₂–Δ¹⁴CO₂ inversion setup for estimating European fossil CO₂ emissions by C. Gómez-Ortiz, G. Monteil, G. Monteil, S. Basu, S. Basu, M. Scholze

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Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings... by Hassan Haghparast-Bidgoli, Michelle Heys, Caroline Crehan, Erin Kesler, Monica Lakhanpaul, Emma Wilson, Fabiana Lorencatto, Felicity Fitzgerald, Mario Cortina Borja, Msandeni Chiume, Hannah Gannon, Simbarashe Chimhuya, Gwendoline Chimhini, Tim Hull-Bailey, Tarisai Chiyaka, Yali Sassoon, Deliwe Nkhoma, Nushrat Khan, Alexander G. Stevenson, Kristina Curtis

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Tracking acute flaccid paralysis in Niger: a half-decade epidemiological portrait (2016–2021) by El Khalef Ishagh, Marc Talatou Ouédraogo, Batouré Oumarou, Mutenda Sheria Kaya, Gbaguidi Aichatou Diawara, Abdoulaye Macire Camara, Seyni Moussa, Kuyangisa Bienvenu, Joseph Toko, Hamidou Harouna, Haladou Moussa, N.’Zue Kofi, Jacques L. Tamuzi, Patrick D. M. C. Katoto, Charles S. Wiysonge, Blanche-Philomene Melanga Anya, Manengu Casimir Tshikolasoni

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Measurement report: Analysis of aerosol optical depth variation at Zhongshan Station in Antarctica by L. Chen, L. Chen, L. Zhang, Y. She, Z. Zeng, Y. Zheng, B. Tian, W. Zhang, Z. Liu, H. Che, M. Ding

“…These findings help us infer AOD variation patterns in the coastal Antarctic based on meteorological changes, providing valuable insights for climate modeling in the context of global climate change.</p>…”
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Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307 by Jie Sheng, Rory Cave, Mary M. Ter-Stepanyan, Siyu Lu, Yingxiong Wang, Taihang Liu, Hermine V. Mkrtchyan

“…Our findings suggest that a transmission event occurred between the two hospitals in Armenia, likely facilitated by patients or community members, during which K. pneumoniae ST307 isolates acquired plasmids carrying AMR and virulence genes.IMPORTANCEMultidrug-resistant (MDR) Klebsiella pneumoniae sequence type (ST) 307 has emerged as a high-risk clone associated with hospital- and community-acquired infections, posing a major threat to global public health. We report in-depth comparative genomics analyses of K. pneumoniae ST307 isolates recovered from patients in Armenia. …”
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An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein... by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

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Perceived healthiness of sugary drinks and related social norms among adults in five countries: evidence from the International Food Policy Study by Virginie Drolet-Labelle, Christine M. White, Jean Adams, Sharon I. Kirkpatrick, Alejandra Jáuregui, Lilia S. Pedraza, Véronique Provencher, Gary Sacks, James F. Thrasher, Gabriela C. Armendariz, Simón Barquera, David Hammond, Lana Vanderlee

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Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort by Giehae Choi, Xiaoshuang Xun, Deborah H. Bennett, John D. Meeker, Rachel Morello-Frosch, Sheela Sathyanarayana, Susan L Schantz, Leonardo Trasande, Deborah Watkins, Edo D. Pellizzari, Wenlong Li, Kurunthachalam Kannan, Tracey J. Woodruff, Jessie P. Buckley

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Determinantes da Gravidez na Adolescência no Município de Malanje, em Angola: Um Estudo Caso-Controlo by Kalonesse Aragão, Euclides Sacomboio, Cristina Teixeira, Joaquim Van-Dúnem, Paulo Campos

“… Introdução: A gravidez na adolescência é um problema global de saúde pública, com taxas mais elevadas na África Subsariana. …”
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Potential impacts of marine fuel regulations on an Arctic stratocumulus case and its radiative response by L. F. Escusa dos Santos, L. F. Escusa dos Santos, H. C. Frostenberg, A. Baró Pérez, A. M. L. Ekman, A. M. L. Ekman, L. Ickes, E. S. Thomson

“…Moreover, over the last decade, the global shipping sector has been subject to regulatory changes that affect the physicochemical properties of exhaust particles. …”
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