Quantifying uncertainties in satellite NO₂ superobservations for data assimilation and model evaluation by P. Rijsdijk, P. Rijsdijk, P. Rijsdijk, H. Eskes, A. Dingemans, A. Dingemans, K. F. Boersma, K. F. Boersma, T. Sekiya, K. Miyazaki, S. Houweling, S. Houweling

“…Recently launched instruments provide increasingly higher spatial resolutions, with footprint diameters in the range of 2–8 km and with daily global coverage for polar orbiting satellites or hourly observations from geostationary orbits. …”
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The health promoting sports coach: theoretical background and practical guidance by Benjamin Tézier, Kévin Barros, Susanna Geidne, Farid Bardid, Spartaco Grieco, Stacey Johnson, Sami Kokko, Barry Lambe, Arthur Lefebvre, Aoife Lane, Linda Ooms, Jan Seghers, Vassilis Sevdalis, Stephen Whiting, Anne Vuillemin, Aurélie Van-Hoye

“…Five stages of progression for integrating health promotion into coaching have been established, ranging from risk prevention to a global approach involving the entire sports system. …”
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Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy by Coraline Radermecker, Pascale Hubert, Patrick Roncarati, Stephanie Demoulin, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Margot Meunier, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs

“…Indeed, without affecting the global number of (CD45+) immune cells, drastic reductions of monocytic/granulocytic myeloid-derived suppressor cells (MDSC) and regulatory T lymphocytes, a higher M1/M2 ratio of macrophages as well as an increased activation of both DC and pDC were continually observed following HMGB1 inhibition. …”
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A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer by Hossein Khorramdelazad, Kowsar Bagherzadeh, Ali Rahimi, Ali Darehkordi, Alireza Najafi, Milad Karimi, Majid Khoshmirsafa, Gholamhossein Hassanshahi, Elaheh Safari, Reza Falak

“…Abstract Background Colorectal cancer (CRC) is a globally prevalent malignancy, primarily affecting the colon and rectum, characterized by uncontrolled cellular changes in the intestinal wall lining. …”
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Post-therapeutic support and rehabilitation for breast cancer women in complete remission in a thermal resort: study protocol for the PACThe Real-Life conditions observational tria... by Mélanie Godiveau, Judith Passildas, Emilie Thivat, Mélanie Casile, Céleste Pinard, Alexia Giro, Marie-Ange Mouret-Reynier, Ioana Molnar, Catherine Abrial, Claude-Eugène Bouvier, Yves-Jean Bignon, Xavier Durando

“…The main analysis will consist of comparing the SF-36 global score at 6 months with the baseline. Discussion This study aims to investigate the improvements in quality of life of 3 weeks stay at thermal resort for breast cancer women in complete remission. …”
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Predictors of developing severe COVID-19 among hospitalized patients: a retrospective study by Hussain Abduljaleel Alkhalifa, Ehab Darwish, Zaenb Alsalman, Aman Alfaraj, Abdullah Alkhars, Fatimah Alkhalifa, Mohammed Algaraash, Ahmed Mohammed Elshebiny, Emad Alkhoufi, Khaled Mohamed Amin Elzorkany

“…BackgroundCOVID-19 poses a significant threat to global public health. As the severity of SARS-CoV-2 infection varies among individuals, elucidating risk factors for severe COVID-19 is important for predicting and preventing illness progression, as well as lowering case fatality rates. …”
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A dehazing and enhancement algorithm for heterogeneous images of underground mining environments in coal mines by Xuhui ZHANG, Yanbin XIE, Wenjuan YANG, Chao ZHANG, Jicheng WAN, Zheng DONG, Yanqun WANG, Jie JIANG, Long LI

“…Methods Initially, hazy images were segmented into zones with different brightness values, for which the average ambient light intensity of global dark channels was calculated. The calculation results were integrated through weighting with the ambient light of local bright channels, which was obtained using adaptive gamma correction and multiscale Gaussian filtering. …”
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Upper circumpolar deep water influences microbial functional gene composition and diversity along the southern Central Indian Ridge and eastern Southwest Indian Ridge by Sheryl Oliveira Fernandes, Dhiraj Paul, Surya Prakash Lankalapalli, Srinivas Rao Arvapalli, Vidya PJ, John Kurian Palayil

“…ABSTRACT Deep sea microbial communities play a significant role in global biogeochemical processes. However, the depth-wise metabolic potential of microbial communities in hydrothermally influenced Central Indian Ridge (CIR) and Southwest Indian Ridge (SWIR) remains elusive. …”
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Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

“…Abstract Hepatocellular carcinoma (HCC) is a predominant cause of cancer-related mortality globally, noted for its propensity towards late-stage diagnosis and scarcity of effective treatment modalities. …”
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Different exercise interventions on quality of sleep in breast cancer survivors—a network meta-analysis of randomized controlled trials by Qi Song, Qi Song, You-kang Zhu, You-kang Zhu, Hai Liu, Hai Liu, Xiao Liu, Xiao Liu, Zhang-dong Jiang, Yu-jia Wang, Yu-jia Wang, Li-yun Xue, Li-yun Xue, Shao-ying Yang, Shao-ying Yang, Xi-fang Liu

“…IntroductionBreast cancer is currently the most prevalent cancer globally; however, it generally has a favorable prognosis and is linked to a high survival rate. …”
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Translation and Validation of the Italian Version of the Team-Based Learning Student Assessment Instrument (TBL-SAI) in Nursing Students by Valeria Vannini, Rosario Caruso, Sara Alberti, Sergio Rovesti, Paola Ferri

“…Validating the TBL-SAI in different languages ensures its applicability and accuracy in diverse educational contexts, supporting the global adoption of TBL methodologies. Thus far, no Italian validation of this tool has been performed. …”
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Alternative psychopharmacologic treatments for pediatric catatonia: a retrospective analysis by Joshua R. Smith, Joshua R. Smith, Isaac Baldwin, Tasia York, Carina Anderson, Trey McGonigle, Simon Vandekar, Lee Wachtel, James Luccarelli, James Luccarelli

“…A retrospective clinical global impressions-improvement (CGI-I) score was assigned by four authors.Results102 pediatric patients diagnosed with catatonia were identified, and 31 met criteria for the study. 20 (65%) were white, 6 (19%) were Black, 4 (13%) were Hispanic, and 1 (3%) were Indian. …”
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Decoding gene expression dynamics in planktonic and biofilm cells of Streptococcus mutans: regulation and role of mutanofactin genes in biofilm formation by Muhammad Afzal, Miguel Carda-Diéguez, Susanne Bloch, Susanne Bloch, Leon G. S. Thies, Alex Mira, Christina Schäffer

“…IntroductionDental caries is the most prevalent chronic infectious disease globally, with Streptococcus mutans recognized as a primary causative agent due to its acidogenicity and robust biofilm-forming ability. …”
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A unique Helicobacter pylori strain to study gastric cancer development by Jeannette M. Whitmire, Ian H. Windham, Morris O. Makobongo, Mandy D. Westland, Sirena C. Tran, Jaume Piñol, Yvonne Hui, Rasha Raheem Alkarkoushi, Oscar Q. Pich, David J. McGee, M. Blanca Piazuelo, Angela Melton-Celsa, Traci L. Testerman, Timothy L. Cover, D. Scott Merrell

“…Our studies indicate that the USU101 strain is a valuable tool to study H. pylori-induced disease.IMPORTANCEGastric cancer is the fifth leading cause of cancer-related death globally; the majority of gastric cancers are associated with Helicobacter pylori infection. …”
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Flowering Characteristics and Expression Patterns of Key Genes in Response to Photoperiod in Different <i>Chrysanthemum</i> Varieties by Qiuling Zhang, Xueru Li, Shuyu Cai, Junzhuo Li, Jiaying Wang, Yanfei Li, Silan Dai

“…<i>Chrysanthemum</i> × <i>morifolium</i> Ramat. is a globally renowned ornamental flower. It includes numerous varieties, most of which are typical short-day (SD) plants, and the flowering characteristics of different <i>chrysanthemum</i> varieties in response to the photoperiod vary greatly. …”
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Epilepsy care pathway: The Finnish model by Reetta Kälviäinen, Zakarya Hadj‐Allal, Jarkko Kirjavainen, Reina Roivainen, Tarja Linnankivi, Jukka Peltola, Kai Eriksson, Salla Lamusuo, Tuire Lähdesmäki, Johanna Annunen, Päivi Vieira, Virpi Tarkiainen, Leena Jutila, Anni Saarela, Leena Kämppi, Liisa Metsähonkala, Eija Gaily, Niina Lähde, Jaana Antinmaa, Sini Erme, Anna‐Leena Pirttisalo, Jari Virolainen, Milla Ylijoki, Laura Kela, Jonna Komulainen‐Ebrahim, Paula Sorjonen, Finnish Severe Epilepsy Coordination Group

“…They must align with the WHO Global Action Plan on Epilepsy, ensuring best practices and cost‐effective management. …”
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The carbon cost of impaired welfare on sheep farms by L. Lanzoni, M.C. Reeves, K. Waxenberg, R. Ramsey, A.S. Atzori, J. Bell, R.M. Rees, G. Vignola, C.M. Dwyer

“…In the face of global climate threats, farm and land-management decisions must balance climate concerns with profitability, animal welfare, and ecosystem health. …”
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Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study by Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li, Zeyu Wang

“…The MR Pleiotropy Residual Sum and Outlier (MR-PRESSO) global test and the MR-Egger regression were used to detect horizontal pleiotropy. …”
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Sacubitril/valsartan in patients with heart failure with reduced ejection fraction with end‐stage of renal disease by Seonhwa Lee, Jaewon Oh, Hyoeun Kim, Jaehyung Ha, Kyeong‐hyeon Chun, Chan Joo Lee, Sungha Park, Sang‐Hak Lee, Seok‐Min Kang

“…Abstract Aims Sacubitril/valsartan (SV) reduced heart failure hospitalization and cardiovascular mortality compared with enalapril in the Prospective Comparison of ARNI with ACE‐I to Determine Impact on Global Mortality and Morbidity in Heart Failure trial. …”
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Clinical outcomes among HIV positive babies below 18 months of age, diagnosed under the Early Infant Diagnosis (EID) programme, India: a mixed-methods studyResearch in context by Suchit Kamble, Nilesh Gawde, Shilpa Bembalkar, Noopur Goel, Mohan Thorwat, Kalyani Nikhare, Sushmita Kamble, Radhika Brahme, Swapna Pawar, Harsh Kubavat, Bhawanisingh Kushwaha, Vinita Verma, Chinmoyee Das, Raman Gangakhedkar

“…Funding: The study was commissioned by the National AIDS Control Programme (T.11020/98/2014-NACO (R&D)) and funded through The Global Fund Against AIDS, TB and Malaria (GFATM) grant.…”
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