Altered functional brain connectivity in Dyt1 knock-in mouse models by R. Z. Adury, B. J. Wilkes, P. Girdhar, Y. Li, D. E. Vaillancourt, D. E. Vaillancourt, D. E. Vaillancourt

“…In this study, we aimed to elucidate the impact of the GAG TorsinA mutation present globally and when restricted to the cortical and hippocampal neurons. …”
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Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

“…Spatial autocorrelation analysis revealed that the Global Moran’s I index for the comprehensive ecological sensitivity in Chongqing consistently exceeded 0, indicating a clear spatial heterogeneity in the sensitivity. …”
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Possible linking and treatment between Parkinson’s disease and inflammatory bowel disease: a study of Mendelian randomization based on gut–brain axis by Beiming Wang, Xiaoyin Bai, Yingmai Yang, Hong Yang

“…Abstract Background Mounting evidence suggests that Parkinson’s disease (PD) and inflammatory bowel disease (IBD) are closely associated and becoming global health burdens. However, the causal relationships and common pathogeneses between them are uncertain. …”
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Evaluation of multidrug resistance in the Gram-negative microbiome of cancer patients and the adverse effects of their metabolites on albino rats and epithelial or fibroblasts cell... by Mervat Morsy Abbas Ahmed El-Gendy, Huda Ahmed Alghamdi, Khaled G. Abdel-Wahhab, Nabila S. Hassan, Aya A. M. El-Bondkly, Mohammed Abdel-Wahab, Ayman A. Farghaly, Ahmed Mohamed Ahmed El-Bondkly

“…Abstract Background Cancer is a significant global health issue due to its high incidence and mortality rates. …”
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Virtual Reality Simulation for Undergraduate Nursing Students for Care of Patients With Infectious Diseases: Mixed Methods Study by Wen Chang, Chun-Chih Lin, Julia Crilly, Hui-Ling Lee, Li-Chin Chen, Chin-Yen Han

“…However, the pandemic highlighted the ongoing global priority of providing care for patients with infectious diseases. …”
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Novel prehospital lactate cut-off estimation for mortality: a multicentre observational study by Ancor Sanz-García, Carlos del Pozo Vegas, Daniel Zalama-Sánchez, Raúl López-Izquierdo, Francisco Martín-Rodríguez, Pedro Ángel de Santos Castro, Eduardo Silva Alvarado, Santos Gracia Villar, Luis Alonso Dzul López, Silvia Aparicio Obregón, Rubén Calderon Iglesias

“…The difference in the median prehospital lactate concentration (mmol/L) between survivors and non-survivors was statistically significant (p<0.001): 2.29 (95% CI 1.43 to 3.38) and 7.14 (95% CI 5.11 to 9.71), respectively. Globally, the cut-off for all the studies combined was estimated by the direct method to be 3.71 mmol/L (95% CI 2.92 to 3.91), which was similar to the indirect value of 3.07 (95% CI 2.95 to 5.49) and the third quartile of 4.00. …”
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Effect of home environment on neuropsychiatric development in preterm infants discharged from NICU at 18 months corrected age by Yuan Tian, Chuncao Zhang, Li Shen, Haifeng Jiang, Feng Liu, Jinjin Chen, Xia Hong

“…Multiple logistic regression analyses showed that compared with infants in supportive home environments, infants with moderate/unsupportive home environments had significantly elevated risks of development delay: 2.162-fold for global (odds ratio (OR) 2.162, 95% confidence interval (CI) 1.274 to 3.665, p=0.004), 2.193-fold for fine motor (OR 2.193, 95% CI 1.161 to 4.140, p=0.016), 2.249-fold for language (OR 2.249, 95% CI 1.336 to 3.786, p=0.002) and 2.042-fold for personal-social (OR 2.042, 95% CI 1.149 to 3.628, p=0.015).Conclusions A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants. …”
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Characteristics associated with career self-reliance behaviors of nurses working in nursing homes in Japan: A cross-sectional study by Ayako Nakayama, Junko Hoshino, Masashi Hotta, Mayuri Hashimoto, Naomi Furukawa

“…Background: With an aging global population, establishing integrated systems for long-term care is challenging in several countries. …”
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Apportioning and Locating PM2.5 Sources Affecting Coastal Cities: Ulsan in South Korea and Dalian in China by Eunhwa Choi, Kwonho Jeon, Young Su Lee, Jongbae Heo, Ilhan Ryoo, Taeyeon Kim, Chuanlong Zhou, Philip K. Hopke, Seung-Muk Yi

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Soft Skills as Predictors of Students’ Life Self-Fulfillment by L. N. Stepanova, E. F. Zeer

“…Introduction. Today, global transformations of the most important institutions of modern society, acceleration of its development and total digitalisation actualise the search for the new and previously unknown determinants of human potential realisation. …”
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Estimation and Analysis of Caspian Region\'s Future Rainfalls by Using General Atmospheric Circulation Models. by alimohammad khorshiddoust, behrooz sarraf, bagher ghermez cheshmeh, fatemeh jafarzadeh

“…On the southern coasts of the Caspian Sea, precipitation as one of the important climatic parameters has undergone changes due to global climate change. In the present study, we tried to evaluate the effect of climate change on rainfall in this region by applying a suitable model. …”
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Structure and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate by Angela Agnew, Ethan Humm, Kang Zhou, Robert P. Gunsalus, Z. Hong Zhou

“…While they are keystone organisms in the global carbon cycle and active members of the human microbiome, there is a general lack of characterization of methanogen enzyme structure and function. …”
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To what extent are digital health interventions targeting HIV care cascade among mobile populations feasible, acceptable, and effective? A mixed methods systematic review protocol by Thulile Mathenjwa, Bessie Malila, Lucia Knight, Frank Tanser, Patricia Makwambeni, Tamsin K. Phillips

“…The results will inform the development of tailored digital health interventions to enhance HIV care delivery and health outcomes for this hard-to-reach population, supporting global HIV prevention and treatment goals. Systematic review registration This protocol is registered on PROSPERO (CRD42024528122).…”
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Multi-Class Guided GAN for Remote-Sensing Image Synthesis Based on Semantic Labels by Zhenye Niu, Yuxia Li, Yushu Gong, Bowei Zhang, Yuan He, Jinglin Zhang, Mengyu Tian, Lei He

“…Our model features a dual-branch architecture with a global generator that captures the overall image structure and a multi-class generator that improves the quality and differentiation of land-cover types. …”
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Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income countries: a case-control study by Dube Jara, Angefa Ayele, Dukele Boneya, Jitu Beka, Miesa Gelchu, Alo Edin

“…Background Low birth weight, as defined by the WHO, refers to the weight of a neonate below 2500 g at birth and is a significant public health concern globally, with both short- and long-term consequences. …”
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CHANNELING: SEARCH OF THE METAANTHROPOLOGIC MEAS-UREMENTS OF MIND BEING IN THE UNIVERSE (based on the World Wide Web) by Anatoly T. Tshedrin

“…Studying the mechanisms of constructing virtual superhuman personalities in the global network is one of the directions of further development of subject- thematic field of anthropology of the Internet as an important area of philosophical and anthropological studies. …”
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تهیه و تحلیل نقشه خطر سیلاب با استفاده از مدل هیدرولیکی HEC RAS و RAS MAPPER (مطالعه موردی: رودخانه سوک چم کاشان)... by دانیال صیاد, رضا قضاوی, ابراهیم امیدوار

“…ابتدا نقشه توپوگرافی با استفاده از Google Earth و Global mapper ساخته شد. سپس با استفاده از نقشه توپوگرافی ساخته شده در محیط نرم‌افزار AutoCAD Civil 3D برای بازه مطالعاتی سطح ایجاد گردید. …”
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Localized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions by Hasan AM, Cavalu S, Kira AY, Hamad RS, Abdel-Reheim MA, Elmorsy EA, El-kott AF, Morsy K, AlSheri AS, Negm S, Saber S

“…The current review begins with an overview of different GI cancers and their impact globally. Then, it discusses the current treatment approaches and their corresponding limitations. …”
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Oleanolic Acid Cubic Liquid Crystal Nanoparticle-Based Thermosensitive Gel Attenuates Depression Symptoms in Chronic Unpredictable Mild Stress Rats by Shi Z, Wang Q, Li Q, Jia F, Xu W

“…Zhiqi Shi,1,2,* Qing Wang,1,* Qing Li,1,3 Fan Jia,1,3 Weifeng Xu1 1Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, Jiangsu, People’s Republic of China; 2Liangxi District Hospital of Traditional Chinese Medicine, Wuxi, Jiangsu, People’s Republic of China; 3Wuxi Institute of Traditional Chinese Medicine, Wuxi, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiqi Shi, Chinese Medicine Research Department, Wuxi, Jiangsu, 214071, People’s Republic of China, Tel +86 510-82725693, Email shi_mars@foxmail.com Weifeng Xu, Drug Clinical Trial Facility Office, Wuxi, Jiangsu, 214071, People’s Republic of China, Tel +86 510-82725693, Email 13585028501@163.comPurpose: Major depressive disorder (MDD) is a global health concern. Studies have demonstrated that oleanolic acid (OA) has a regulatory effect on MDD. …”
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Comparative Evaluation of AI-Based Multi-Spectral Imaging and PCR-Based Assays for Early Detection of <i>Botrytis cinerea</i> Infection on Pepper Plants by Dimitrios Kapetas, Eleni Kalogeropoulou, Panagiotis Christakakis, Christos Klaridopoulos, Eleftheria Maria Pechlivani

“…Pepper production is a critical component of the global agricultural economy, with exports reaching a remarkable $6.9B in 2023. …”
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