Immune checkpoint inhibitor‐related type 1 diabetes incidence, risk, and survival association by Fumika Kamitani, Yuichi Nishioka, Miyuki Koizumi, Hiroki Nakajima, Yukako Kurematsu, Sadanori Okada, Shinichiro Kubo, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura, Yutaka Takahashi

“…ABSTRACT Aim/Introduction Although immune checkpoint inhibitor‐related type 1 diabetes mellitus (ICI‐T1DM) is a rare condition, it is of significant concern globally. We aimed to elucidate the precise incidence, risk factors, and impact of ICI‐T1DM on survival outcomes. …”
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Correlations among lymphocyte count, white matter hyperintensity and brain atrophy in patients with ischemic stroke by Chenchen Liu, Dai Shi, Xiaoqiong Ni, Shoujiang You, Shoujiang You, Xiaofen Wu, Sheng Zhuang, Sheng Zhuang, Wu Cai, Liang Xu, Liang Xu

“…Brain atrophy was defined as global cortical atrophy score ≥ 1. Multivariable logistic regression models were used to assess the association between lymphocyte count and WMH and brain atrophy.ResultsAmong 727 AIS, 517 (71.1%), 442 (60.8%), 459 (63.1%), 583 (80.2%) had WMH, PVH, DWMH and brain atrophy, respectively. …”
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Exploring Innovative Approaches for the Analysis of Micro- and Nanoplastics: Breakthroughs in (Bio)Sensing Techniques by Denise Margarita Rivera-Rivera, Gabriela Elizabeth Quintanilla-Villanueva, Donato Luna-Moreno, Araceli Sánchez-Álvarez, José Manuel Rodríguez-Delgado, Erika Iveth Cedillo-González, Garima Kaushik, Juan Francisco Villarreal-Chiu, Melissa Marlene Rodríguez-Delgado

“…These particles, typically less than 5 mm, are found globally, from deep seabeds to human tissues, and are known to adsorb and release harmful pollutants, exacerbating ecological and health risks. …”
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Using remote sensing and machine learning to generate 100-cm soil moisture at 30-m resolution for the black soil region of China: Implication for agricultural water management by Liwen Chen, Boting Hu, Jingxuan Sun, Y. Jun Xu, Guangxin Zhang, Hongbo Ma, Jingquan Ren

“…To assess the applicability of our research methodology, we selected the typical black soil zone in Northeast of China, which is one of the four major black soil regions globally and characterized by intensive agricultural activities. …”
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Characterizing avocado production systems for Ugandan exports: the need for consolidation and support for sustainable development by Peter Sseruwagi, Peter Sseruwagi, Edouard Lehmann, Paul Sigombe, Gabriel Ddamulira, Jan Willem Van Casteren, Pieterjan De Bauw

“…Hass avocado production and trade are rapidly expanding globally, with increasing consumer demands on quality, safety and sustainability. …”
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What Affects Agricultural Green Total Factor Productivity in China? A Configurational Perspective Based on Dynamic Fuzzy-Set Qualitative Comparative Analysis by Danni Lu, Xinhuan Zhang, Degang Yang, Shubao Zhang

“…Agricultural production faces the dual challenge of increasing output while ensuring efficient resource utilization and environmental sustainability amid escalating global climate change and relentless increases in human demand. …”
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Exploring Disparities in Gill Physiological Responses to NaHCO₃-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I... by Shicheng Han, Lin Han, Fangying Yuan, Wenzhi Liu, Jing Wang, Xiaofeng Jin, Yanchun Sun

“…<b>Background</b>: Owing to the progressive rise in saline waters globally, resulting in detrimental impacts on freshwater aquaculture, the underlying molecular distinctions governing the response to alkaline stress between diploid and triploid crucian carp remain unknown. …”
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Scaling Arctic landscape and permafrost features improves active layer depth modeling by Wouter Hantson, Daryl Yang, Shawn P Serbin, Joshua B Fisher, Daniel J Hayes

“…Tundra ecosystems in the Arctic store up to 40% of global below-ground organic carbon but are exposed to the fastest climate warming on Earth. …”
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Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis by Loïs Bolko, Loïs Bolko, Loïs Bolko, Céline Anquetil, Céline Anquetil, Alba Llibre, Solène Maillard, Damien Amelin, Karim Dorgham, Vincent Bondet, Océane Landon-Cardinal, Océane Landon-Cardinal, Océane Landon-Cardinal, Ségolène Toquet, Ségolène Toquet, Kuberaka Mariampillai, Samuel Malatre, Alexandrine Mahoudeau, Baptiste Hervier, Mathieu Rodero, Guy Gorochov, Darragh Duffy, Olivier Benveniste, Olivier Benveniste, Yves Allenbach, Yves Allenbach

“…ObjectiveThe objective of this study was to evaluate the presence of different types of interferon in idiopathic inflammatory myopathies (IIM) and their subgroups using ultrasensitive cytokine detection techniques (SIMOA) and to assess their potential as activity biomarkers.MethodsDisease activity was measured at the time of serum collection and assessed by manual muscle testing eight (MMT8 score 0-150), muscle enzymes to calculate the Physician Global Assessment (PGA) (0-10). Patients were classified as active if PGA&gt;5.Serum IFN-α and IFN-γ levels was measured using the single molecule array (SIMOA) technique. …”
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Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial by Joanna Schellenberg, Charles Opondo, Tanya Marchant, Lars Åke Persson, Masresha Tessema, Atkure Defar, Alemneh Kabeta Daba, Girum Taye, Senait Alemayehu, Elias Asfaw, Anene Tesfa, Bedasa Tessema, Kalkidan Zenebe

“…Dissemination of findings will also inform global decision making, particularly in settings where a transition from iron-folic acid to multiple micronutrient supplementation is being contemplated at scale.Trial registration number NCT05708183.…”
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Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan by Sabahat Abdullah, Sabahat Abdullah, Muhammad Ahmad Mushtaq, Kalim Ullah, Brekhna Hassan, Mariya Azam, Mariya Azam, Muhammad Asif Zahoor, Juan Wang, Jianzhen Xu, Mark A. Toleman, Mashkoor Mohsin

“…Plasmid-mediated mobile colistin-resistant (mcr) genes in Escherichia coli (E. coli) are disseminated globally and are considered to be a major public health threat. …”
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How do leaf functional traits influence above-ground tree carbon in tropical hill forests of Bangladesh? by Ariful Khan, Md Rezaul Karim, Mohammed A.S. Arfin-Khan, Md. Shamim Reza Saimun, Fahmida Sultana, Sharif A. Mukul

“…This study enhances our understanding of how leaf functional traits influence AGTC stocks, underscoring the importance of localized investigations for global climate change mitigation efforts and supporting sustainable forest management in Bangladesh.…”
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Minimal disease activity and associated factors in patients with psoriatic arthritis: cross-sectional study from a single center by Murat Bektas, Berk Çelik, Burak İnce, Yasemin Yalçınkaya, Bahar Artım Esen, Ahmet Gül, Murat İnanç

“…Patients who met at least 5 of 7 criteria (tender joint count ≤ 1/68, swollen joint count ≤ 1/66, Psoriasis Area Severity Index [PASI] ≤ 1, Visual Analogue Scale [VAS] ≤ 15, patient global VAS ≤ 20, Health Assessment Questionnaire-Disability Index [HAQ-DI] ≤ 0.5, and enthesitis number ≤ 1) were considered to achieve MDA. …”
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Comprehensive metabolite profiling and evaluation of anti-nociceptive and anti-inflammatory potencies of Nypa fruticans (Wurmb.) leaves: Experimental and in-silico approaches by Farhana Islam, Md. Aktaruzzaman, Md. Tarikul Islam, Fariya Islam Rodru, Saquiba Yesmine

“…Globally, inflammation and pain are among the most prevalent health issues. …”
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Late-life physical activity, midlife-to-late-life activity patterns, APOE ε4 genotype, and cognitive impairment among Chinese older adults: a population-based observational study by Xunying Zhao, Xueyao Wu, Tianpei Ma, Jinyu Xiao, Xin Chen, Mingshuang Tang, Li Zhang, Tao Zhang, Mengyu Fan, Jiaqiang Liao, Ben Zhang, Xia Jiang, Jiayuan Li

“…Late-life PA and midlife-to-late-life activity patterns were assessed using the Global Physical Activity Questionnaire and a standardized question, respectively. …”
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Lasting and extensive consequences of left mesial temporal lobe seizures on electrical cortical activity by Mathieu Dhoisne, Nacim Betrouni, Sophie Hennion, Lucie Plomhause, Arnaud Delval, Philippe Derambure

“…Background and objectives: Focal epilepsies disrupt long-range networks with seizure recurrence driving both regional and global alterations in connectivity networks. While prior studies have focused on the interictal consequences, limited data exist on the direct aftermath of focal seizures. …”
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Rapeseed Supports Hairy Vetch in Intercropping, Enhancing Root and Stem Morphology, Nitrogen Metabolism, Photosynthesis, and Forage Yield by Jianli Ji, Zongkai Wang, Pan Gao, Xiaoqiang Tan, Xianling Wang, Jie Kuai, Jing Wang, Zhenghua Xu, Bo Wang, Guangsheng Zhou, Jie Zhao

“…The global shortage of high-quality forage has significantly constrained the development of animal husbandry. …”
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The Minimum Dietary Diversity For Women Indicator Can Be Extended To Children And Adolescents aged 4-15 Years As A Proxy Population Indicator For Good Micronutrient Adequacy Of Die... by Loty Diop, Aulo Gelli, Lieven Huybregts, Joanne E Arsenault, Lilia Bliznashka, Erick Boy, Megan Deitchler, Carl Lachat, Mourad Moursi, Angelica M Ochoa-Avilés, Deanna K Olney, Elodie Becquey

“…Background: The response to the global call for more data on children’s and adolescents’ diets and nutrition is limited by the lack of straightforward practical indicators to track their diet quality. …”
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The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

“…Secondary outcomes include skin specific quality of life, eczema control, itch severity, use of usual eczema treatments, proportion who achieve an improvement in POEM of ≥3 points, global change in eczema and safety outcomes. A sample of participants will also be invited to a semi-structured interview to discuss their experience. …”
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Exploring the pivotal variables of tongue diagnosis between patients with chronic kidney disease and health participants by Po-Chi Hsu, Po-Chi Hsu, Jia-Ming Chen, Jia-Ming Chen, Chia-Chu Chang, Yu-Jun Chang, Ping-Fang Chiu, John Y. Chiang, John Y. Chiang, Lun-Chien Lo, Lun-Chien Lo

“…IntroductionChronic kidney disease (CKD) is a significant global health problem associated with high morbidity and mortality rates. …”
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