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21661
FedDrip: Federated Learning With Diffusion-Generated Synthetic Image
Published 2025-01-01“…Non-IID data poses challenges to the convergence of FL models, such as client drifting, where the model weights drift towards local optima instead of the global optimum. As a solution, leveraging synthetic data not only addresses data distribution issues but also helps overcome data scarcity. …”
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21662
Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty
Published 2025-01-01“…Abstract Introduction In 2020, 368 million people globally were affected by knee osteoarthritis, and prevalence is projected to increase with 74% by 2050. …”
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21663
Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry
Published 2024-12-01“…Disease activity, evaluated by physician-reported (physician’s global assessment, disease remission, C-reactive protein, serum amyloid A, erythrocyte sedimentation rate) and patient-reported (autoinflammatory disease activity index diary, disease activity, fatigue, impact on social life) measures, was generally well controlled throughout the study. …”
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21664
Socio-economic inequalities in minimum dietary diversity among Ethiopian children aged 6–23 months: a decomposition analysis
Published 2025-01-01“…BackgroundGlobally, inappropriate feeding practices account for more than two-thirds of all cases of child mortality during the first 2 years of a child’s life. …”
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21665
Examining internet use for health information seeking and influencing factors among undergraduate health science students in Southwest Ethiopia
Published 2025-01-01“…Background: The Internet has become a pivotal resource for accessing health information globally, offering unprecedented convenience and breadth of resources. …”
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21666
Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz
Published 2020-01-01“…Tuberculosis is still a global public health problem, with an estimated 10 million new cases and 1.6 million deaths in 2017. …”
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21667
Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: pro...
Published 2025-01-01“…Introduction Yeast beta-glucan (YBG) are recognised for enhancing the immune system by activating macrophages, a key defence mechanism. Given the global prevalence and impact of upper respiratory tract infections (URTIs) on productivity and healthcare costs, YBG has shown promise as a potential therapeutic and preventive strategy for recurrent respiratory tract infections. …”
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21668
Differential expression of circulating microRNAs in lactating Holstein and Jersey cows exposed to heat stress
Published 2024-12-01“…Holstein cows, the primary dairy breed globally, are particularly sensitive to heat stress. …”
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21669
Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran
Published 2025-02-01“…Abstract Background Health Workers Safety (HWS) is a global health priority and essential at all times, in stable situations, in emergencies, in disease epidemics or pandemics. …”
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21670
Do current maternal health staffing and bed occupancy benchmarks work in practice? Results from a simulation model
Published 2024-05-01“…Introduction The WHO has issued the global target of reducing maternal mortality rates by two-thirds of 2010 baseline levels by 2030. …”
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21671
A Step Forward Towards Exploring Nutritional and Biological Potential of Mushrooms: A Case Study of Calocybe gambosa (Fr.) Donk Wild Growing in Serbia
Published 2022-01-01“…Edible mushrooms have been appreciated globally for their organoleptic, nutritional and chemical properties. …”
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21672
Phytocompounds from Indonesia Medicinal Herbs as Potential Apelin Receptor Agonist for Heart Failure Therapy: An In-silico Approach
Published 2025-01-01“… Heart failure is still a global health problem that demands new pharmacological treatments. …”
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21673
Ultrasound-assisted modification of oat protein isolates: Structural and functional enhancements
Published 2025-01-01“…Escalating global protein demand necessitates the commercialization of protein rich products. …”
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21674
Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS)
Published 2025-01-01“…Addressing this question represents a need for ensuring global health and wellbeing to all individuals in a world facing the progressive increase of aging and aging related diseases. …”
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21675
The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis
Published 2025-01-01“…Very low to moderate quality evidence showed that APOE4 carriers benefitted more than APOE4 non-carriers on cognitive (e.g. executive function, learning) and physical (e.g. relative telomere length) outcomes after exercise; and that APOE4 non-carriers benefited over carriers for physical (serum BDNF, gait speed) and cognitive (global cognition, verbal memory) markers. Very low quality evidence indicated that there was no evidence of difference between APOE4 carriers and non-carriers on physical function outcomes in meta-analysis. …”
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21676
Deep learning–based assessment of missense variants in the COG4 gene presented with bilateral congenital cataract
Published 2025-01-01“…Different pathogenicity metrics were aggregated with principal component analysis (PCA) and further analysed at three levels (amino acid position, substitution and post-translation) based on all possible Cog4 missense variants (n=14 915).Results Localised protein structural impact including change of conformation and amino acid polarity, breakage of hydrogen bond and salt-bridge, and formation of alpha-helix were identified among clinically relevant Cog4 variants. The global structural comparison with multidimensional scaling demonstrated variants with similar protein structures (AF2) tended to exhibit similar clinical and biological phenotypes. …”
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21677
Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation
Published 2025-02-01“…Objectives Providing adequate access to mental health services is a global challenge. Smartphone apps offer a potentially cost-effective, available and accessible solution for monitoring, supporting and treating mental health conditions. …”
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21678
Ambient PM2.5 Temporal Variation and Source Apportionment in Mbarara, Uganda
Published 2024-01-01“…Abstract Air pollution is the leading environmental cause of death globally, and most mortality occurs in resource-limited settings such as sub-Saharan Africa. …”
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21679
Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation
Published 2021-08-01“…ABSTRACT Marine fungi remain poorly covered in global genome sequencing campaigns; the 1000 fungal genomes (1KFG) project attempts to shed light on the diversity, ecology and potential industrial use of overlooked and poorly resolved fungal taxa. …”
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21680
Hepatobiliary scintigraphy and liver function changes in patients with hepatocellular carcinoma treated with 166Ho-radioembolization
Published 2025-01-01“…None of the patients had clinical signs of liver decompensation (Child Pugh ≤ B7, median MELD 9 or ALBI − 2.55). Global and regional hepatic function was based on manual delineation of HBS using 200 MBq 99mTc-mebrofenine, acquired during screening and approximately three months after 166Ho-radioembolization, referred to as liver clearance rate (LCR). …”
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