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  1. 21661

    FedDrip: Federated Learning With Diffusion-Generated Synthetic Image by Karin Huangsuwan, Timothy Liu, Simon See, Aik Beng Ng, Peerapon Vateekul

    Published 2025-01-01
    “…Non-IID data poses challenges to the convergence of FL models, such as client drifting, where the model weights drift towards local optima instead of the global optimum. As a solution, leveraging synthetic data not only addresses data distribution issues but also helps overcome data scarcity. …”
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  2. 21662

    Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty by Henriëtte M. Eijking, Isobel M. Dorling, Emil H. van Haaren, Roel Hendrickx, Thijs Nijenhuis, Martijn G.M. Schotanus, Lee Bouwman, Jasper Most, Bert Boonen

    Published 2025-01-01
    “…Abstract Introduction In 2020, 368 million people globally were affected by knee osteoarthritis, and prevalence is projected to increase with 74% by 2050. …”
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  3. 21663

    Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry by Prasad T. Oommen, Tilmann Kallinich, Juergen Rech, Norbert Blank, Julia Weber-Arden, Jasmin B. Kuemmerle-Deschner

    Published 2024-12-01
    “…Disease activity, evaluated by physician-reported (physician’s global assessment, disease remission, C-reactive protein, serum amyloid A, erythrocyte sedimentation rate) and patient-reported (autoinflammatory disease activity index diary, disease activity, fatigue, impact on social life) measures, was generally well controlled throughout the study. …”
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  4. 21664
  5. 21665
  6. 21666

    Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz by Enrique Ortega, Sujhey Hernández-Bazán, Beatriz Sánchez-Hernández, Ileana Licona-Limón, Javier Fuentes-Dominguez

    Published 2020-01-01
    “…Tuberculosis is still a global public health problem, with an estimated 10 million new cases and 1.6 million deaths in 2017. …”
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  7. 21667

    Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: pro... by Suzana Shahar, Kalavathy Ramasamy, Norhayati Ibrahim, Nur Nadia Mohamad Habibullah, Munirah Ismail, Mohd Zul Amin Kamaruddin, Shirley Gee Hoon Tang, Mohd Faisal Abdul Hamid

    Published 2025-01-01
    “…Introduction Yeast beta-glucan (YBG) are recognised for enhancing the immune system by activating macrophages, a key defence mechanism. Given the global prevalence and impact of upper respiratory tract infections (URTIs) on productivity and healthcare costs, YBG has shown promise as a potential therapeutic and preventive strategy for recurrent respiratory tract infections. …”
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  8. 21668
  9. 21669

    Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran by Jafar Sadegh Tabrizi, Mondher Letaief, Hossein Mashhadi Abdolahi, Ramin Rezapour, Ahmed Alboksmaty, Mostafa Farahbakhsh

    Published 2025-02-01
    “…Abstract Background Health Workers Safety (HWS) is a global health priority and essential at all times, in stable situations, in emergencies, in disease epidemics or pandemics. …”
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  10. 21670

    Do current maternal health staffing and bed occupancy benchmarks work in practice? Results from a simulation model by Giorgia Gon, Carolin Vegvari, Rebecca F Baggaley, Said Mohammed Ali, Salma Abdi Mahmoud, Farhat Jowhar

    Published 2024-05-01
    “…Introduction The WHO has issued the global target of reducing maternal mortality rates by two-thirds of 2010 baseline levels by 2030. …”
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  11. 21671
  12. 21672
  13. 21673
  14. 21674

    Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS) by Francesca Tonelli, Cecilia Masiero, Carla Aresi, Camilla Torriani, Simona Villani, Guido Premoli, Antonio Rossi, Antonella Forlino

    Published 2025-01-01
    “…Addressing this question represents a need for ensuring global health and wellbeing to all individuals in a world facing the progressive increase of aging and aging related diseases. …”
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  15. 21675

    The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis by Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred

    Published 2025-01-01
    “…Very low to moderate quality evidence showed that APOE4 carriers benefitted more than APOE4 non-carriers on cognitive (e.g. executive function, learning) and physical (e.g. relative telomere length) outcomes after exercise; and that APOE4 non-carriers benefited over carriers for physical (serum BDNF, gait speed) and cognitive (global cognition, verbal memory) markers. Very low quality evidence indicated that there was no evidence of difference between APOE4 carriers and non-carriers on physical function outcomes in meta-analysis. …”
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  16. 21676

    Deep learning–based assessment of missense variants in the COG4 gene presented with bilateral congenital cataract by Shaohua Zhang, Yang Sun, Yinghong Ji, Li Ning, Binghe Xiao, Maierdanjiang Ainiwaer, Houyi Liu, Yingying Hong

    Published 2025-01-01
    “…Different pathogenicity metrics were aggregated with principal component analysis (PCA) and further analysed at three levels (amino acid position, substitution and post-translation) based on all possible Cog4 missense variants (n=14 915).Results Localised protein structural impact including change of conformation and amino acid polarity, breakage of hydrogen bond and salt-bridge, and formation of alpha-helix were identified among clinically relevant Cog4 variants. The global structural comparison with multidimensional scaling demonstrated variants with similar protein structures (AF2) tended to exhibit similar clinical and biological phenotypes. …”
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  17. 21677

    Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation by Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli

    Published 2025-02-01
    “…Objectives Providing adequate access to mental health services is a global challenge. Smartphone apps offer a potentially cost-effective, available and accessible solution for monitoring, supporting and treating mental health conditions. …”
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  18. 21678

    Ambient PM2.5 Temporal Variation and Source Apportionment in Mbarara, Uganda by Silver Onyango, Crystal M. North, Hatem A. Ellaithy, Paul Tumwesigye, Choong-Min Kang, Vasileios Matthaios, Martin Mukama, Nuriat Nambogo, J. Mikhail Wolfson, Stephen Ferguson, Stephen Asiimwe, Lynn Atuyambe, Data Santorino, David C. Christiani, Petros Koutrakis

    Published 2024-01-01
    “…Abstract Air pollution is the leading environmental cause of death globally, and most mortality occurs in resource-limited settings such as sub-Saharan Africa. …”
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  19. 21679
  20. 21680

    Hepatobiliary scintigraphy and liver function changes in patients with hepatocellular carcinoma treated with 166Ho-radioembolization by Margot T.M. Reinders, Maarten J.L. Smits, Karel van Erpecum, Joep de Bruijne, Rutger C.G. Bruijnen, Dave Sprengers, Rob de Man, Erik Vegt, Jan N.M. IJzermans, Marnix G.E.H. Lam, Arthur J.A.T. Braat

    Published 2025-01-01
    “…None of the patients had clinical signs of liver decompensation (Child Pugh ≤ B7, median MELD 9 or ALBI − 2.55). Global and regional hepatic function was based on manual delineation of HBS using 200 MBq 99mTc-mebrofenine, acquired during screening and approximately three months after 166Ho-radioembolization, referred to as liver clearance rate (LCR). …”
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