Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set... by Huan Gao, Xue Zhang, Ziqi Liu, Xiaoge Yang, Yajie Li, Mengxing Cui, Han Wang, Xiaoyu Chen, Weiying Zhang, Zhihan Liu, Yongjiang Yu, Liping Chen, Daochuan Li, Yongmei Xiao, Wen Chen, Qing Wang

“…Next, we developed a global adverse outcome pathway (AOP) network based on the existed AOP-wiki. …”
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HSRoadNet: Hard-Swish Activation Function and Improved Squeeze–Excitation Module Network for Road Extraction Using Satellite Remote Sensing Imagery by Xunqiang Gong, Yingjie Ma, Ailong Ma, Zhaoyang Hou, Meng Zhang, Yanfei Zhong

“…Ablation experiments show that the proposed method performs best in various indices, and the global accuracy, MIoU, class average accuracy, and recall rate are improved by 0.5%, 0.1%, 0.5%, and 0.2%, respectively, compared with the suboptimal method. …”
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Connections Across Open Water: A Bi‐Organelle, Genomics‐Scale Assessment of Atlantic‐Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark (Isurus oxyrinchus) by Andrea M. Bernard, Marissa R. Mehlrose, Kimberly A. Finnegan, Bradley M. Wetherbee, Mahmood S. Shivji

“…One such species, the shortfin mako shark (Isurus oxyrinchus), a globally widespread, highly migratory predator, has undergone dramatic population reductions and is now Endangered (IUCN Red List), with Atlantic Ocean mako sharks in particular assessed by fishery managers as overfished and in need of urgent, improved management attention. …”
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Genome-wide association analysis and KASP markers development for protein quality traits in winter wheat by Yousheng Tian, Pengpeng Liu, Dezhen Kong, Yingbin Nie, Hongjun Xu, Xinnian Han, Wei Sang, Weihua Li

“…Thise research will offer valuable insights for wheat breeding programs in China and globally.…”
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Being a tree crop increases the odds of experiencing yield declines irrespective of pollinator dependence by Aizen, Marcelo A., Gleiser, Gabriela, Kitzberger, Thomas A., Milla, Ruben

“…Alternatively, widespread tree mortality has been directly and indirectly related to global climate change, which could also explain yield decreases in tree crops. …”
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A novel approach to skin disease segmentation using a visual selective state spatial model with integrated spatial constraints by Yu Bai, Hai Zhou, Hongjie Zhu, Shimin Wen, Binbin Hu, Haotian Li, Huazhang Wang, Daji Ergu, Fangyao Liu

“…This efficient model, termed ‘SSR-UNet,’ leverages bidirectional scanning to capture both global and local features in image data, achieving strong performance with low computational complexity. …”
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DEVELOPMENT OF CLIP THINKING OF HIGHER EDUCATION STUDENTS IN INFORMATION ENVIRONMENT by Sergey Bushuyev, Halyna Korchova, Yurii Krasylnyk, Mykola Rudenko, Borys Kozyr

“… Global trends and sources of formation of clip thinking in the field of digitalization of educational systems are studied. …”
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Research status of traditional & complementary medicine systems across the world by Vedvati Bhapkar, Vallari Nisargand, Pawankumar Godatwar, Supriya Bhalerao

“…The stakeholders of these systems need to establish a strong evidence base at par with biomedicine. United efforts at global level through organizations such as WHO-Global Traditional Medicine Centre (GTMC) might be helpful in this regard.…”
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EFFECT OF AUDIT QUALITY ATTRIBUTES AND IFRS ADOPTION ON FINANCIAL REPORTING QUALITY OF LISTED MANUFACTURING FIRMS IN NIGERIA by Aisha Chado Muhammad

“…This is because audit quality is an essential element in achieving global financial stability and high-quality financial reporting. …”
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Tecovirimat in the management of poxviruses: a narrative review of available evidence by Olalekan John Okesanya, Jerico Bautista Ogaya, Ikponmwosa Jude Ogieuhi, Mohamed Mustaf Ahmed, Bonaventure Michael Ukoaka, Ojoisimi Franca Jamgbadi, Deborah Oluwaseun Shomuyiwa, Don Lucero-Prisno Eliseo, Blessing Olawunmi Amisu, Olakulehin Adebusuyi, William K. Chung, Emery Manirambona, Nimat Bola Idris, Janet Alexis A. De los Santos

“…With the rise in monkeypox (mpox) cases globally, there is an urgent need to explore therapeutic options to manage potential outbreaks. …”
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Adapting to ulcerative colitis to try to live a ‘normal’ life: a qualitative study of patients’ experiences in the Midlands region of England by Rachel Cooney, Christel McMullan, Dmitri Nepogodiev, Laura Magill, Thomas D Pinkney, Jonathan M Mathers, Laura L Jones, Shri Pathmakanthan

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Risk factors for Carbapenem-resistant Enterobacterales infections: A case-control study by Sibongakonke Mbele, Sandeep D. Vasaikar

“…Background: Over years, concerning Carbapenem-resistant Enterobacterales (CRE) have advanced globally, posing a major threat to global health. Prior studies highlight previous antibiotic use and prolonged hospital stays as paramount risk factors for CRE infections. …”
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KNOWLEDGE, ATTITUDES AND PRACTICES TOWARDS OPEN EDUCATIONAL RESOURCES IN HIGHER EDUCATION INSTITUTIONS IN THE PHILIPPINES by Liezel G. Mohillo, Angie R. Jalandoon, Dave E. Marcial

“… Open educational resources (OER) are well-known around the world and globally it gives revenue to Higher Education Institutions (HEIs). …”
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Is rewilding too wild? Assessing the benefits and challenges of forest succession on abandoned land in the mid‐hills of Nepal by Nicola McGunnigle, Douglas Bardsley, Ian Nuberg, Bishnu Hari Pandit

“…In Nepal and elsewhere globally, forest is also regenerating naturally on abandoned agricultural land, effectively rewilding the landscape by default. …”
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Impact of topical cetylated fatty acid cream on hand osteoarthritis: a randomized, double-blind clinical trial by Sitthiphong Suwannaphisit, Nitiphoom Sinnathakorn, Pormes Suwanno, Warangkana Fongsri, Boonsin Tangtrakulwanich

“…The secondary outcome measures included the Visual Analog Score (VAS), Patient Global Assessment (PGA), and skin irritation at 2, 4, and 6 weeks. …”
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Correlation of Platelet Indices with Severity of Gastroesophageal Varices in Patients of Liver Cirrhosis: A Research Protocol by Parav Tantia, Sourya Acharya

“…Cirrhosis is the advanced stage of ongoing liver fibrosis, which poses substantial global health challenges due to its fatal consequences, such as gastroesophageal varices. …”
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Real-world smartphone-based point-of-care diagnostics in primary health care to monitor HbA1c levels in people with diabetes by Sabrina Rhode, Lisa Rogge, Marthoenis Marthoenis, Till Seuring, Hendra Zufry, Till Bärnighausen, Hizir Sofyan, Jennifer Manne-Goehler, Sebastian Vollmer

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Redox-mediated reverse water gas shift integrated with ammonia cracking over Ni/La0.75Sr0.25Cr0.5Mn0.5O3−δ by Martin Keller, Shih-Yuan Chen, Atul Sharma

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Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study by Mai M. El-Daly, Leena H. Bajrai, Thamir A. Alandijany, Isra M. Alsaady, Hattan S. Gattan, Meshari M. Alhamdan, Vivek Dhar Dwivedi, Esam I. Azhar

“…Abstract The Zika virus (ZIKV), a member of the Flaviviridae family, has caused multiple widespread outbreaks, posing significant challenges to global health. This study explores the potential of compounds from Echinacea angustifolia (E. angustifolia) to inhibit the activity of ZIKV’s RNA-dependent RNA polymerase (RDRP), a key enzyme in the viral replication process and an ideal candidate for antiviral therapy. …”
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Trend in burden of rheumatoid arthritis in China from 1990 to 2021 by WEN Jiaxin，JIANG Junpeng，FENG Min，SHEN Xiaochen，LI Xiaoyin

“…Objective:To analyze the trend in burden of rheumatoid arthritis (RA) in China from 1990 to 2021, so as to provide insights into reducing the RA burden in China. Methods:Data of Global Burden of Disease Study 2021 were collected, and the incidence, mortality and disability-adjusted life years (DALY) of RA in China from 1990 to 2021 were analyzed and compared with global and different Socio-demographic Index (SDI) regions. …”
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