All-Trans Retinoic Acid Inhibits Bone Marrow Mesenchymal Stem Cell Commitment to Adipocytes via Upregulating FRA1 Signaling by Linjun Xie, Liying Zou, Jie Chen, Youxue Liu

“…Obesity, caused by an increased number and volume of adipocytes, is a global epidemic that seriously threatens human health. …”
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Effect of Different Types of Mulching on Soil Properties and Tree Growth of Magnolia champaca Planted at the Montane Rainforest in Cameron Highlands, Pahang, Malaysia by Wahidullah Rahmani, Mohd Nazre Salleh, Mohd Zaki Hamzah, Aminu Abdu, Mohamad Fakhri Ishak, Wan Rasidah Wan Abd Khadir, Mohd Ridza Awang, Zahari Ibrahim, Ahmad Fadzil Abd Majid, Mohd Shahrir Azrin Salleh, Azhar Anuar, Mohamad Azani Bin Alias

“…Tropical Montane Cloud Forest (TMCF) is among the most vulnerable habitats to fragmentation, deforestation, and global climate change. A successful restoration program requires a comprehensive understanding of variables influencing seedling efficiency. …”
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The Impact of Farmland Transfer on Urban–Rural Integration: Causal Inference Based on Double Machine Learning by Yuchen Lu, Jiakun Zhuang, Jun Chen, Chenlu Yang, Mei Kong

“…Urban–rural fragmentation represents a significant challenge encountered by nations globally, particularly in both developing and developed contexts, during the modernisation process. …”
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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…Abstract Background The emerging incidence of pathogenic liver conditions is turning into a major concern for global health. Induction of pyroptosis in hepatocytes instigates cellular disintegration, which in turn liberates substantial quantities of pro‐inflammatory intracellular substances, thereby accelerating the advancement of liver fibrosis. …”
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Effectiveness and safety of an emergency department-based rapid response system by Fanny Delfanti, Guido Bertolini, Giovanni Nattino, Giulia Acquistapace, Daniela De Palma, Piergiuseppe Ferrari, Sara Martinenghi, Stefano Maiandi, Marco Rossi, Anna Lilia Ruocco, Maria Teresa Spina, Benedetta Chiodi, Stefano Paglia

“…Rapid Response Systems (RRSs) are designed to assist hospitalized patients who become unstable, aiming to address “failure to rescue” and prevent cardiac arrests. Despite global implementation, evidence of RRS effectiveness is controversial. …”
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Few-shot Remote Sensing Imagery Recognition with Compositionality Inductive Bias in Hierarchical Representation Space by Shichao Zhou, Zhuowei Wang, Zekai Zhang, Wenzheng Wang, Yingrui Zhao, Yunpu Zhang

“…We introduce a hierarchical context prediction mechanism for compositional representation learning, utilizing a predictive NCE loss function to encourage global remote sensing scenes to accurately predict similar local parts, and thus automatically inferring compositional representations of high-level but discriminative latent concepts. …”
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A Review on Performance Calculation and Design Methodologies for Horizontal-Axis Wind Turbine Blades by Rongyu Zha, Siyuan Wu, Chang Cai, Xiaohui Liu, Dian Wang, Chaoyi Peng, Xuebin Feng, Qiuhua Chen, Xiaohui Zhong, Qing’an Li

“…A critical introduction to various methods is provided, along with a key viewpoint centered around design philosophy: there is no global optimal solution; instead, the most suitable solution is chosen from the Pareto set according to the design philosophy. …”
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The rationale, design of the Assisted reproductive technology cohort nested in a pre-pregnancy family cohort (APP-Cohort) by Wei Xiong, Qinghan Liang, Xiaojie Han, Qiaolu Cheng, Qihang Liu, Xifang Zuo, Huiyu Wang, Huijing He, Guangliang Shan

“…Introduction Infertility has become a major global issue due to the trend of delaying marriage and advanced maternal age. …”
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The Impact of Private Standards on Corporate Social Responsibility Compliance and Rural Workers’ Motivation in Developing Countries: A Study of Mango Farms in Pakistan by Honglei Tang, Zeeshan Rasool, Ahmad Imran Khan, Anum Afzal Khan, Mohsin Ali Khan, Ghulam Ahmad Azaz

“…Pakistan is the fifth largest mango producer in the world and the fourth largest exporter in global mango trade; also, mango is the biggest fruit crop within the country. …”
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Examining The Impact of The COVID-19 Pandemic On Pediatric Orthopedic Cases: A Systematic Review and Meta-Analysis by Ahmadin Yusuf Rizal Susatyo, Nizar Al Rhaazi, Farhan Haidar Fazlur Rahman, Ismail Hadisoebroto Dilogo

“…Background: This study examines the adverse effects of COVID-19 pandemic on pediatric orthopedics globally, including decreased patient admissions. The adverse effects of pandemic on pediatric orthopedic patients and surgeries have not been determined. …”
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Effect of Sodium Azide on Quantitative and Qualitative Stem Traits in the M2 Generation of Ethiopian Sesame (Sesamum indicum L.) Genotypes by Micheale Yifter Weldemichael, Yemane Tsehaye Baryatsion, Desta Berhe Sbhatu, Girmay Gebresamuel Abraha, Hagos Mohammedseid Juhar, Abraha Birhan Kassa, Fiseha Baraki Sibhatu, Hailay Mehari Gebremedhn, Tesfakiros Semere Gebrelibanos, Mohammed Mebrahtu Mossa, Mullubrhan Mekonen Gebru, Birhanu Kahsay Meresa, Medhin Teklay, Birhanu Debesay Berhe, Haftay Abadi Gebru

“…The emerging oilseed crop Sesamum indicum, also known as the queen of oilseeds, is being grown globally for its oil content for medicinal and nutritional values. …”
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Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis by Fang-Chen Gong, Ran Ji, Yu-Ming Wang, Zhi-Tao Yang, Ying Chen, En-Qiang Mao, Er-Zhen Chen

“…Sepsis remains a major global concern and is associated with high mortality and morbidity despite improvements in its management. …”
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Spatiotemporal Variability of Hot Days in Association with the Large-Scale Atmospheric Drivers over Vietnam by Chinh Ta Huu, Tan Phan Van, Khiem Mai Van, Thang Vu Van, Lam Hoang Phuc, Worapong Lohpaisankrit, Quoc Bao Pham, Trinh Trong Nguyen, Phong Nguyen Thanh

“…The severe heatwaves and hot spells in Vietnam were observed more frequently in intensity and duration due to global warming and climate change impacts. The hot days and extreme summer events make the weather harsh and significantly affect human health and the environment. …”
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Effectiveness of acid-tolerant antagonist-based biofungicide in the control of basal stem rot disease caused by ganoderma in oil palm seedlings on peat soil by Supriyanto, Sulistyowati Henny, Arifin Nur, Ruliyansyah Agus, Haris Ramadahan Tris

“…As the world’s largest palm oil producer, Indonesia has always been associated with global warming because most of its plantation areas are on peatlands and their management is considered not environmentally friendly. …”
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Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano by Biodun Bintu Adebakin, Mayor Orezime Atima, Ugbede Idakwo, Jamilu Abubakar Bala, Alhasan Sharif Abdullahi, Auwal Bello Muhammad, Jah Douglas Pam, Emeka John Dingwoke, Florence Olufunke Darda

“…Objective Ocular toxoplasmosis, caused by Toxoplasma gondii, is a significant cause of posterior uveitis and vision impairment globally. Accurate diagnosis is essential to prevent retinal damage and optimise treatment. …”
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Challenges of community participation in health emergency and disaster risk management in an Iranian context: a qualitative study by Mohammad Azim Mahmodi, Mehrdad Farrokhi, Seyyed Mohammad Reza Hosseini, Mehdi Najafi, Mohammad Esmaeel Motlagh, Hamid Reza Khankeh

“…BackgroundDisasters are considered one of the major threats to the health of communities. Given the global spread of disasters, there has been a renewed emphasis in recent years on using community participation approaches in disaster risk management. …”
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Comparative growth kinetics and drug susceptibility of Mycobacterium tuberculosis lineages prevalent in Ethiopia: implications for tuberculosis treatment and management by Tesfaye Gebreyohannis Hailemariam, Tesfaye Gebreyohannis Hailemariam, Melaku Tilahun, Abay Atnafu, Tesfaye Gelanew, Tewodros Tariku Gebresilase, Mekdes Alemu Tola, Abaysew Ayele, Shewki Moga Siraj, Workineh Shibeshi, Kidist Bobosha, Liya Wassie, Yonas Hirutu, Ephrem Engidawork

“…Tuberculosis (TB) remains a global health challenge, with treatment outcomes influenced by the genetic diversity of Mycobacterium tuberculosis (Mtb) strains. …”
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Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors by Shudong Lin, Guanghua Zhu, Juan Xie, Xuanwei Wen, Limin Deng, Sijing Li, Guozhi Liu, Feiyan Wang, Shuangxi Chen, Zijian Xiao

“…Currently, there is a global shortage of safe and effective treatments for this condition. …”
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Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…The combination of two parallel discriminators in P-GAN provides additional feedback to the generator to more faithfully recover both local and global cellular structures. Imaging data from 8 eyes of 7 participants were used in this study. …”
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Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing by Maham Tanveer, Karina Klein, Brigitte von Rechenberg, Salim Darwiche, Hannah L. Dailey

“…High gap strain appears to be a transient local limiter of osteogenesis, not a global inhibitor of secondary fracture repair. Cite this article: Bone Joint Res 2025;14(1):5–15.…”
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