Impacts of Tax Laws on the Performance of Small and Medium Enterprises: A Case Study of Kabale Municipality Kabale District. by Abaasa, Ruth

“…Additionally, it sought to evaluate how current tax regulations affect SMEs in Kabale Municipality, investigate potential policy recommendations, and assess how tax compliance costs impact SME performance, particularly their ability to compete globally. The study also aimed to determine the challenges SMEs face in complying with tax laws and explore potential policy recommendations and strategies to improve the tax environment for SMEs and promote their growth. …”
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Plasmodium Falciparum Genetic Diversity and Multiplicity of Infection Among Asymptomatic and Symptomatic Malaria-Infected Individuals in Uganda. by Mwesigwa, Alex, Ocan, Moses, Cummings, Bryan, Musinguzi, Benson, Kiyaga, Shahid, Kiwuwa, Steven M., Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Karamagi, Charles, Nankabirwa, Joaniter I., Nsobya, Samuel L., Byakika‐Kibwika, Pauline

“…Plasmodium falciparum (P. falciparum) remains a significant public health challenge globally, especially in sub-Saharan Africa (SSA), where it accounts for 99% of all malaria infections. …”
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Systematic Review and Meta-Analysis on Human African Trypanocide Resistance by Keneth Iceland, Kasozi, Ewan Thomas, MacLeod, Susan Christina, Welburn

“…Conclusion: The emergence of drug resistance across the spectrum of trypanocidal agents that are used to treat HAT is a major threat to the global WHO target to eliminate HAT by 2030. T. brucei strains were largely resistant to diamidines and the use of high trypanocide concentrations in clinical studies have proved fatal in humans. …”
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Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa by Keneth Iceland, Kasozi, Zirintunda, Gerald, Ssempijja, Fred, Buyinza, Bridget, Alzahrani, Khalid J., Matama, Kevin, Nakimbugwe, Helen N., Alkazmi, Luay, Onanyang, David, Bogere, Paul, Ochieng, Juma John, Islam, Saher, Matovu, Wycliff, Nalumenya, David Paul, Batiha, Gaber El-Saber, Osuwat, Lawrence Obado, Abdelhamid, Mahmoud, Shen, Tianren, Omadang, Leonard, Welburn, Susan Christina

“…While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse. …”
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25 years of providing evidence on road safety interventions at the city level by Katherine Pérez, Katherine Pérez, Katherine Pérez, Elena Santamariña-Rubio, Maria José López, Maria José López, Maria José López, Maria José López, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Josep Ferrando, Carlos Pastor, Adnan A. Hyder, Carme Borrell, Carme Borrell, Carme Borrell

“…Road traffic injuries are a significant public health concern, ranking among the leading causes of mortality and disability-adjusted life years lost globally, especially among the young population. Traditionally, road safety has been approached predominantly from a healthcare standpoint, with limited interventions from a comprehensive public health perspective. …”
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Characterizing avocado production systems for Ugandan exports: the need for consolidation and support for sustainable development by Peter Sseruwagi, Peter Sseruwagi, Edouard Lehmann, Paul Sigombe, Gabriel Ddamulira, Jan Willem Van Casteren, Pieterjan De Bauw

“…Hass avocado production and trade are rapidly expanding globally, with increasing consumer demands on quality, safety and sustainability. …”
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Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis by Loïs Bolko, Loïs Bolko, Loïs Bolko, Céline Anquetil, Céline Anquetil, Alba Llibre, Solène Maillard, Damien Amelin, Karim Dorgham, Vincent Bondet, Océane Landon-Cardinal, Océane Landon-Cardinal, Océane Landon-Cardinal, Ségolène Toquet, Ségolène Toquet, Kuberaka Mariampillai, Samuel Malatre, Alexandrine Mahoudeau, Baptiste Hervier, Mathieu Rodero, Guy Gorochov, Darragh Duffy, Olivier Benveniste, Olivier Benveniste, Yves Allenbach, Yves Allenbach

“…ObjectiveThe objective of this study was to evaluate the presence of different types of interferon in idiopathic inflammatory myopathies (IIM) and their subgroups using ultrasensitive cytokine detection techniques (SIMOA) and to assess their potential as activity biomarkers.MethodsDisease activity was measured at the time of serum collection and assessed by manual muscle testing eight (MMT8 score 0-150), muscle enzymes to calculate the Physician Global Assessment (PGA) (0-10). Patients were classified as active if PGA>5.Serum IFN-α and IFN-γ levels was measured using the single molecule array (SIMOA) technique. …”
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Effect of prenatal multiple micronutrient supplementation on birth weight in Ethiopia: protocol for a pragmatic cluster-randomised trial by Joanna Schellenberg, Charles Opondo, Tanya Marchant, Lars Åke Persson, Masresha Tessema, Atkure Defar, Alemneh Kabeta Daba, Girum Taye, Senait Alemayehu, Elias Asfaw, Anene Tesfa, Bedasa Tessema, Kalkidan Zenebe

“…Dissemination of findings will also inform global decision making, particularly in settings where a transition from iron-folic acid to multiple micronutrient supplementation is being contemplated at scale.Trial registration number NCT05708183.…”
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Exposure to triphenyl phosphate during pregnancy: The role of gut-bile acids-liver axis on lipid metabolism in male offspring by Juntong Lin, Fuhui Yan, Longhui Liu, Ganzhong Liao, Yilei Xu, Qian Liu, Miaoliang Wu, Honghui Guo, Bai Zhi, Lianxian Guo, Xiaoshan Liu

“…The widespread use of Triphenyl phosphate (TPhP) as a substitute flame retardant in various commercial products has raised global concerns for its health risks. Previously, we found that gestational and lactational TPhP exposure disturbed lipid metabolism and gut microbiota in offspring sex-dependently. …”
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CO2 methanation over low-loaded Ni-M, Ru-M (M = Co, Mn) catalysts supported on CeO2 and SiC by Chopendra G. Wasnik, Maki Nakamura, Taiki Shimada, Hiroshi Machida, Koyo Norinaga

“…The concentration of the major greenhouse gas CO2 is rapidly increasing in the atmosphere, leading to global warming and a range of environmental issues. …”
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Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…Efficacy outcomes evaluated in person at baseline, 12 weeks and 24 weeks include the FMA (total, upper extremity and lower extremity motor scores), modified Rankin Scale (mRS), Patient-Reported Outcomes Measurement Information System–Global Health (PROMIS-10) and NIHSS. Additionally, telephone assessment at week 4 includes the simplified mRS and PROMIS-10.Safety will be evaluated by standard assessments and occurrence of adverse events over the duration of the study.Discussion Interventions that enhance recovery beyond the acute period of stroke are needed. …”
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Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment by Kai Zhang, Xiaoxia Liu, Siyu Huang, Xinrui Liu, Meiqi Zhao, Chao Xue, Shijun Xia, Jianzeng Dong, Yu Kong, Changsheng Ma

“…LV diastolic dysfunction (Beta [SE], 0.234 [0.045]; P < 0.001) and IVST (Beta [SE], 0.034 [0.016]; P = 0.036) were negatively correlated with the MoCA score of global cognitive function. LV diastolic dysfunction (OR, 2.03; 95% CI, 1.48–2.79; P < 0.001) and IVST (OR, 1.14; 95% CI, 1.03–1.27; P = 0.014) were positively associated with MCI, independent of diagnosed CVDs and the conventional MCI risk factors. …”
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Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest by Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

“…Acute kidney injury (AKI) was defined based on the “Kidney Disease: Improving Global Outcomes (KDIGO)” guidelines. AKI recovery was defined as a decrease in serum creatinine below the level determined in the definition of AKI. …”
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L-shaped association between dietary iron intake and HPV infection: a cross-sectional analysis based on national health and nutrition examination survey 2005–2016 by Xiaotong Chen, Haiwei Chen, Yuling Chen, Lixin Tang, Jiaqi Liu, Yu-Hua Ou

“…BackgroundHuman Papillomavirus (HPV) infection is a ubiquitous sexually transmitted infection globally, frequently associated with sexual behaviors characterized by increased frequency and multiple partnerships. …”
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Formation and fate of freshwater on an ice floe in the Central Arctic by M. M. Smith, N. Fuchs, E. Salganik, D. K. Perovich, I. Raphael, M. A. Granskog, K. Schulz, M. D. Shupe, M. D. Shupe, M. Webster

“…Terms such as the annual sea ice freshwater production and meltwater storage in ponds could be used in future work as diagnostics for global climate and process models. For example, the range of values from the CESM2 climate model roughly encapsulate the observed total freshwater production, while storage in melt ponds is underestimated by about 50 %, suggesting pond drainage terms as a key process for investigation.…”
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Knowledge and perception of stroke management practices among middle-aged residents of Otolo community in Nnewi North Local Government Area, Nigeria by Uchenna Prosper Okonkwo, Chidera Chibuikem Fortunate, Sochima Johnmark Obiekwe, Uchechukwu Martha Chukwuemeka, Christiana Nkiru Okafor, Augustine Asiduba Igwe, Jovita Ada Daniel

“…Abstract Background Stroke is a leading cause of morbidity and mortality globally, with Nigeria having one of the highest stroke mortality rates in Africa. …”
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AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease by Lulu Zhang, Yi Zheng, Mingyan Shao, Aiping Chen, Meiyi Liu, Wenlong Sun, Tianxing Li, Yini Fang, Yang Dong, Shipeng Zhao, Hui Luo, Juan Feng, Qi Wang, Lingru Li, Yanfei Zheng

“…Metabolic-associated fatty liver disease (MAFLD) is a chronic, progressive disorder characterized by hepatic steatosis and excessive lipid accumulation. Its high global adult prevalence (approximately 50.7 %) is a significant concern worldwide. …”
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Expression pattern of lncRNA H19 in oral squamous cell carcinoma tissues in comparison to normal tissues. A systematic review by Ramya Sekar, Selvaraj Jayaraman, Saranya Varadarajan, Thodur Madapusi Balaji, Vishnupriya Veeraraghavan, Prabhu Shankar Dayasankar, Dharshini Devi J

“…Background: With a high mortality rate, oral squamous cell carcinoma (OSCC), accounts for more than 90 % of all mouth cancers and is a major global health concern. The necessity for trustworthy biomarkers is highlighted by the fact that early diagnosis and prognosis are still difficult despite advancements. …”
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Influence of diglyme and cumene additives upon emission and combustion behaviour of diverse biodiesel fuelled diesel engine by Swarup Kumar Nayak, Dinesh Babu Munuswamy, Ganesan Subbiah, Mallireddy Naresh, Yuvarajan Devarajan

“…The growing need for sustainable and eco-friendly fuels aligns with global efforts to achieve the United Nations Sustainable Development Goals (SDGs), particularly SDG 7 (Affordable and Clean Energy), SDG 13 (Climate Action), and SDG 12 (Responsible Consumption and Production). …”
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Advancing early detection of organ damage and cardiovascular risk prevention: the Suzhou cardiometabolic health study protocol - exploring the role of oral microbiome and metabolic... by Mengmeng Zhu, Mengmeng Zhu, Yiwen Li, Wenting Wang, Longkun Liu, Wenwu Liu, Jiayu Yu, Qian Xu, Jing Cui, Yanfei Liu, Keji Chen, Yue Liu, Yue Liu

“…BackgroundCardiovascular Disease (CVD) is the leading cause of global mortality, with its incidence rate rising year by year due to the prevalence of metabolic diseases. …”
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