Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…Abstract Background Chronic diseases such as diabetes and hypertension pose significant health and economic challenges globally, and South Korea is no exception. Innovative digital health services have the potential to revolutionize chronic disease management by providing patients with real-time, personalized care and empowering them to take an active role in their health. …”
Get full text

Adiponectin and Nitric Oxide Deficiency-Induced Cognitive Impairment in Fatigued Home-Resident in Mature and Older Adults: A Case-Control Study by Ahmad H. Alghadir, Sami A. Gabr, Murad Almomani, Fidaa Almomani, Cynthia Tse

“…VO2 max and the prevalidated global physical activity questionnaire were used to estimate physical status. …”
Get full text

Clinical Evaluation of Faricimab in Real-World Diabetic Macular Edema in India- A Multicenter Observational Study by Chakraborty D, Das S, Maiti A, Sinha TK, Das A, Sheth J, Boral SK, Mondal S, Nandi K

“…Debdulal Chakraborty,1 Sudipta Das,2 Aniruddha Maiti,3 Tushar Kanti Sinha,1 Arnab Das,1 Jay Sheth,4 Subhendu Kumar Boral,1 Soumen Mondal,1 Krishnendu Nandi2 1Disha Eye Hospitals, Kolkata, India; 2Nethralayam Superspeciality Eye Care, Kolkata, India; 3Global Eye Hospitals, Kolkata, India; 4Department of Retina Services, Shantilal Shanghvi Eye Institute (SSEI), Mumbai, IndiaCorrespondence: Debdulal Chakraborty, Department of Vitreo-retinal Services, Disha Eye Hospitals, 88 Ghosh Para Road Barrackpore, Kolkata, West Bengal, 700120, India, Tel +91 33 6636 0000, Email devdc@rediffmail.comPurpose: To evaluate the efficacy of faricimab in real-world clinical settings in India for treating diabetic macular edema (DME) in treatment-naïve and recalcitrant eyes.Patients and Methods: This retrospective study involved 39 eyes (16 treatment-naive and 23 recalcitrant) treated with intravitreal faricimab at four centers in India. …”
Get full text

Air-liquid interface culture alters the characteristics and functions of monolayers generated from human iPS cell‑derived enterocyte‑like cell organoids by Tatsuya Inui, Yusei Uraya, Yukiko Ueyama-Toba, Hiroyuki Mizuguchi

Get full text

SCIENTIFIC PARADIGM SHIFT AS THE BACKGROUND OF LANGUAGE EDUCATION by V. D. Tabanakova

“…The author emphasizes the need to consider the problems of higher education in philosophical aspect, through the interaction of a scientific and educational paradigm.Results and scientific novelty. At a time of global changes in domestic higher education the linguistic education is considered to be a display of the convergence process of natural sciences, technology and humanities. …”
Get full text

Midwives’ knowledge and perspectives on neonatal resuscitation and survival before and after Helping Babies Breathe training: a qualitative study in Uganda by Anna Bergstrom, Josaphat Byamugisha, Susanna Myrnerts Höök, Marielle Abrahamsson, Sarah Namusoko

Get full text

The Effect of a Patient Activation Tailored Intervention on Type 2 Diabetes Self-Management and Clinical Outcomes: A Study from Saudi Arabian Primary Care Settings by Nasser Almutairi, Vinod Gopaldasani, Hassan Hosseinzadeh

“…Type 2 diabetes mellitus (T2DM) is a global public health challenge. T2DM self-management, including diet, physical activity, blood glucose self-monitoring, foot care, and adherence to medication, is considered a primary tool for managing diabetes. …”
Get full text

Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study by Abdurrazzaq Alege, Olayinka Rasheed Ibrahim, Rasheedat Mobolaji Ibraheem, Olajide Aladesua, Abubakar Sani Lugga, Yunusa Yusuf Yahaya, Abdallah Sanda, Bello Muhammed Suleiman

Get full text

O papel da Urina-1 e microscopia urinária no diagnóstico da injúria renal aguda by Camila Lima, Maria de Fatima Correa, Etienne Macedo

“…O critério utilizado para o diagnóstico da IRA foi o Kidney Disease Improving Global Outcomes (KDIGO), baseado apenas na creatinina sérica em 1 semana. …”
Get full text

The effect of educational intervention based on the mobile application on women’s knowledge, attitude, and practice on microplastics and health: study protocol for a randomized con... by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…The primary solution to this global problem lies in significantly reducing the amount of plastic entering the environment. …”
Get full text

Two studies in one: A propensity-score-matched comparison of fingolimod versus interferons and glatiramer acetate using real-world data from the independent German studies, PANGAEA... by Jonathan Alsop, Jennie Medin, Christian Cornelissen, Stefan Viktor Vormfelde, Tjalf Ziemssen

“…For change in disease severity from baseline (assessed by clinicians using the Clinical Global Impressions scale; PANGAEA, n = 1207; PEARL, n = 427), a larger proportion of patients had subjective improvement and a smaller proportion had worsening status in PANGAEA than PEARL (improvement: 28.2% vs 15.2%; worsening: 16.4% vs 30.4%; p < 0.0001).…”
Get full text

Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…Empowering women and men to choose the number and timing of children is a global goal and enhances both maternal and child health. …”
Get full text

Influence of Injection Pressure on the Dual-Fuel Mode in CI Engines Fueled with Blends of Ethanol and Tamanu Biodiesel by M. Parthasarathy, P. V. Elumalai, M. Murunachippan, P. B. Senthilkumar, Saboor Shaik, Mohsen Sharifpur, Nima Khalilpoor

“…The acceleration of global warming is primarily attributable to nonrenewable energy sources such as conventional fossil fuels. …”
Get full text

Evaluating catastrophic health expenditures among patients with long bone fractures in Ghana's major teaching hospitals: a hospital-based analysis by Alexis D. B. Buunaaim, Michel Adurayi Amenah, Dominic Konadu-Yeboah, Richard Baidoo, Amgbo Asare, Wilfred Larbi Addo, Claude Martin

Get full text

Depression Detection and Diagnosis Based on Electroencephalogram (EEG) Analysis: A Systematic Review by Kholoud Elnaggar, Mostafa M. El-Gayar, Mohammed Elmogy

“…Consequently, depression has become a significant public health issue globally. Electroencephalogram (EEG) data can be utilized to diagnose mild depression disorder (MDD), offering valuable insights into the pathophysiological mechanisms underlying mental disorders and enhancing the understanding of MDD. …”
Get full text

Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…Following this, our larval behavioral (photomotor and acoustic response assays) at environmentally relevant, sub-μM concentrations showed significant hypoactivity, indicating sensorimotor deficits within exposed embryo. We then assessed global DNA methylation using a combination of whole-mount immunohistochemistry and ELISA for 5-methylcytosine (5-mC) and showed significant IPP-induced hypermethylation within whole embryo in situ. …”
Get full text

Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

“…We assessed interpretability by grouping the global MTBQ scores into zero and tertiles (&gt;0) and comparing participant characteristics across these categories.Results Cognitive interviews found good acceptability and content validity. …”
Get full text

The effects of deprivation, age, and regional differences in COVID-19 mortality from 2020 to 2022: a retrospective analysis of public provincial data by Anqi A. Chen, Elizabeth M. Renouf, Charmaine B. Dean, X. Joan Hu

“…Abstract Background Coronavirus disease (COVID-19) quickly spread around the world after its initial identification in Wuhan, China in 2019 and became a global public health crisis. COVID-19 related hospitalizations and deaths as important disease outcomes have been investigated by many studies while less attention has been given to the relationship between these two outcomes at a public health unit level. …”
Get full text

Patterns of self-harm presentations at a Tertiary Urban Hospital in Kenya: A retrospective 5-year study (2018-2022). by Willie Njoroge, Catherine Gitau, Everline Onchari, Linnet Ongeri, Linda Khakali, Murad Khan, Zul Merali, Lukoye Atwoli, Jasmit Shah

“…<h4>Introduction</h4>Self-harm represents a complex and multifaceted public health issue of global significance, exerting profound effects on individuals and communities alike. …”
Get full text

Factors impacting hospitalisation and related health service costs in cancer survivors in Australia: Results from a population data linkage study in Queensland (COS‐Q) by Katharina M. D. Merollini, Louisa G. Collins, Andrew T. Jones, Joanne F. Aitken, Michael G. Kimlin

“…Abstract Background The global economic cost of cancer and the costs of ongoing care for survivors are increasing. …”
Get full text