The association of BMI and subclinical myocardial dysfunction in breast cancer patients after single or dual anti-HER2 targeted therapy by Feng Zhang, Siyuan Wang, Chao Yu, Wenying Jin, Dan He, Xiaoxiao Hu, Shu Wang, Tiangang Zhu

“…Methods In our study, 40 breast cancer patients after single anti-HER2 targeted therapy, and 40 breast cancer patients after dual anti-HER2 targeted therapy were enrolled. Global longitudinal strain (GLS) was measured through echocardiography. …”
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Deep-learning-based canopy height model generation from sub-meter resolution panchromatic satellite imagery by Charles J Abolt, Javier E Santos, Adam L Atchley, Lucas Wells, Daithi Martin, Russell A Parsons, Rodman R Linn

“…Because the model operates on satellite data with global coverage and a relatively short return interval, we propose its suitability to extrapolate tree-level canopy height data to remote regions and conduct high-temporal resolution monitoring of forest structure. …”
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Medicinal plants with anti-SARS-CoV activity repurposing for treatment of COVID-19 infection: A systematic review and meta-analysis by EBENEZER OLUWAKEMI, BODEDE OLUSOLA, AWOLADE PAUL, JORDAAN MARYAM A., OGUNSAKIN ROPO E., SHAPI MICHAEL

“…The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus) has emerged as a significant threat to public health with startling drawbacks in all sectors globally. This study investigates the practicality of some medicinal plants for SARS-CoV-2 therapy using a systematic review and meta-analysis of their reported SARS-CoV-1 inhibitory potencies. …”
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A Cross-sectional Survey of Physicians to Understand Biomarker Testing and Treatment Patterns in Patients with Prostate Cancer in the USA, EU5, Japan, and China by Christian Gratzke, Himani Aggarwal, Jeri Kim, Holly Chaignaud, Sabine Oskar

“…Patient summary: We surveyed physicians globally about their experience in treating patients with advanced prostate cancer and genetic testing. …”
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Varroa Volatiles Offer Chemical Cues to Honey Bees for Initial Parasitic Recognition by Qinglong Zhao, Xinning Wang, Ahsan Mustafa, Ying Wang, Hongfang Wang, Xuepeng Chi, Baohua Xu, Zhenguo Liu

“…The ectoparasitic mite <i>Varroa destructor</i> poses a significant threat to the health of the honey bee <i>Apis mellifera</i> worldwide and has garnered global attention. To better understand the chemical ecology of this host–parasite relationship, we collected and characterized the volatile organic compounds (VOCs) from <i>V. destructor</i> and used electroantennography (EAG) to record the responses of honey bee (<i>A. c. cerana</i> and <i>A. m. ligustica</i>) antennae to the different VOCs. …”
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Air temperature and precipitation constraining the modelled wetland methane emissions in a boreal region in northern Europe by T. Aalto, A. Tsuruta, J. Mäkelä, J. Müller, J. Müller, M. Tenkanen, E. Burke, S. Chadburn, Y. Gao, V. Mannisenaho, T. Kleinen, H. Lee, H. Lee, A. Leppänen, T. Markkanen, S. Materia, P. A. Miller, D. Peano, O. Peltola, B. Poulter, M. Raivonen, M. Saunois, D. Wårlind, S. Zaehle

“…Six ecosystem models (JSBACH-HIMMELI, LPX-Bern, LPJ-GUESS, JULES, CLM4.5, and CLM5) are compared to multi-model means of ecosystem models and atmospheric inversions from the Global Carbon Project and upscaled eddy covariance flux results for their temperature and precipitation responses and seasonal cycles of the regional fluxes. …”
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Management of CAR-T cell therapy in patients with multiple myeloma: a systematic review and expert consensus in Australia by P. Joy Ho, Hang Quach, M. Hasib Sidiqi, M. Hasib Sidiqi, Cindy H. Lee, Jason Butler, Andrew Spencer, Kenneth Micklethwaite, Kenneth Micklethwaite, Kenneth Micklethwaite, Kenneth Micklethwaite, Jingya Li, Elissa Cusson, Robert Bagnall, Simon J. Harrison

“…Consensus was defined a priori as at least 70% agreement on survey questions.ResultsThe SLR identified 22 interventional or observational studies and 5 clinical practice guidelines reporting on selection and management of patients with MM treated with CAR-T cell therapy from various global regions. The Delphi panel reached consensus on practices related to patient referral, screening, selection, prioritization, treatments requiring wash-out, bridging therapy, lymphodepletion, infusion, and post-infusion monitoring and management. …”
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Ethiopia hygiene practice during complementary feeding and associated factors; systematic review and meta-analysis by Getnet Alemu Andargie, Kedir Seid, Gebeyehu Lakew, Amlaku Nigusie Yirsaw, Alemshet Yirga Berhie, Asnake Gashaw Belayneh, Solomon Ketema Bogale, Eyob Ketema Bogale, Eyob Getachew

“…A search strategy was implemented using electronic databases (Medline, Global Health, Google Scholar, Web of Science, Embase, CINAHL, and Psyc INFO) as well as grey literature. …”
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Investigating the meteorological factors influencing upper respiratory tract infections: An observational study by Yeşim Yüksel, Cihan Bedel, Fatih Selvi, Okkes Zortuk, Yusuf Karanci

“…Background: Upper Respiratory Infections (URIs) rank among the most prevalent illnesses affecting people globally. Understanding the environmental factors that contribute to the transmission of these infections is essential for effective public health planning and intervention strategies.Objective: This study aims to explore how various meteorological conditions impact the incidence of URIs across different seasons.Methods: We conducted a retrospective observational study involving patients who visited a tertiary education and research hospital in 2023. …”
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Multidimensional analysis and enhancement strategies for ecological environment quality at the county level under dual carbon goals: a case study of Shaanxi Province, China by Jianfeng Li, Jianfeng Li, Jianfeng Li, Yongxin Hu, Yongxin Hu, Jian Li, Liangyan Yang, Liangyan Yang, Jie Yan

“…With the intensification of global climate change and environmental degradation, the goals of carbon peaking and carbon neutrality have become crucial strategies for promoting sustainable development in various countries. …”
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Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Introduction Primary hypertension (PH) affects over one billion individuals globally, yet less than 30% achieve controlled blood pressure (BP) with medication. …”
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Multi-decade northward shift of loggerhead sea turtle pelagic habitat as the eastern North Pacific Transition Zone becomes more oligotrophic by Dana K. Briscoe, Dana K. Briscoe, Larry B. Crowder, George H. Balazs, Jeffrey A. Seminoff, Alberto Abreu, Catherine A. Lee Hing, Masanori Kurita, Masanori Mori, Denise M. Parker, Marc R. Rice, Tomomi Saito, Bianca S. Santos, Calandra N. Turner Tomaszewicz, Noah Yamaguchi, Jeffrey J. Polovina

“…The North Pacific Transition Zone (NPTZ) is known as a global marine hotspot for many endangered and commercially significant highly mobile marine species. …”
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Facilitators and barriers affecting the implementation of e-health for chronic respiratory diseases in remote settings: a qualitative evidence synthesis by Emil Matias Salmi, Francesca Wanda Basile, Faiz Ahmad Khan, Larry Watt, Rinn Song, Else Margreet Bijker

“…Abstract Background Chronic respiratory diseases are important causes of disability and mortality globally. Their incidence may be higher in remote locations where healthcare is limited and risk factors, such as smoking and indoor air pollution, are more prevalent. …”
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Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis by Chi-Fen Chang, Lih-Chyang Chen, Yei-Tsung Chen, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

“…<b>Background:</b> Prostate cancer is a major global health burden, with biochemical recurrence (BCR) following radical prostatectomy affecting 20–40% of patients and posing significant challenges to prognosis and treatment. …”
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A comprehensive investigation of Clerodendrum Infortunatum Linn. using LC-QTOF-MS/MS metabolomics as a promising anti-alzheimer candidate by Fatma Atef, Mostafa A. Abdelkawy, Basma M. Eltanany, Laura Pont, Ahmed M. Fayez, Mohamed F. Abdelhameed, Fernando Benavente, Inas Y. Younis, Asmaa M. Otify

“…Abstract Alzheimer’s disease (AD) poses a global health challenge, demanding innovative approaches for effective treatments. …”
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Autophagy activation in response to cigarette smoke: Exploring the disparity in laryngeal cancer incidence and outcomes between sexes in South Korea by Min Ji Kim, Jisu Hong, Hyo Won Chang, Yun-Hee Lee, Jun-Pyo Myong, Ah Ra Jung, Yoon Se Lee, Minsu Kwon

“…Introduction: Laryngeal cancer (LC) presents a significant health challenge globally, with smoking being a major risk factor. Interestingly, LC incidence in females is significantly lower than in males; however, female smokers are more likely to develop Reinke edema (RE) than LC. …”
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Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis by Weijia Dang, Tianqi Hao, Ning Li, Hualin Zhang, Ziqi Li, Hongmei Yu, Yalu Wen, Deqiang Zheng, Long Liu

“…By leveraging summary statistics from genome-wide association studies, we investigated global genetic correlations using linkage disequilibrium score regression, genetic covariance analysis, and high-definition likelihood. …”
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Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis by Ganesh Sharma, Neeraj Kumar, Chandra Shekhar Sharma, Taha Alqahtani, Yewulsew Kebede Tiruneh, Sharifa Sultana, Gabriel Vinícius Rolim Silva, Gabriela de Lima Menezes, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira

“…Abstract The COVID-19 pandemic caused by SARS-CoV-2 continues to pose a major challenge to global health. Targeting the main protease of the virus (Mpro), which is essential for viral replication and transcription, offers a promising approach for therapeutic intervention. …”
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Heterogeneity of avian infectious bronchitis virus population by Ye. V. Ovchinnikova, L. O. Scherbakova, S. N. Kolosov, A. N. Andriyasova, N. G. Zinyakov, Z. B. Nikonova, A. A. Kozlov, P. B. Akshalova, D. A. Altunin, D. B. Andreychuk

“…Avian infectious bronchitis is one of the most common viral infections causing enormous economic losses in the global poultry industry. Due to the lack of mechanisms to correct errors during genome replication, the virus can quickly mutate and generate new strains. …”
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Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

“…IntroductionType 2 diabetes (T2D) is a complex metabolic disorder with significant global health implications. Understanding the molecular mechanisms underlying T2D is crucial for developing effective therapeutic strategies. …”
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