Differential expression of circulating microRNAs in lactating Holstein and Jersey cows exposed to heat stress by Jihwan Lee, Doosan Kim, Byeonghwi Lim, Gyeonglim Ryu, Hyeonguk Baek, Joohwan Kim, Seungmin Ha, Sangbum Kim, Seunghwan Lee, Taejeong Choi, Inchul Choi

“…Holstein cows, the primary dairy breed globally, are particularly sensitive to heat stress. …”
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Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran by Jafar Sadegh Tabrizi, Mondher Letaief, Hossein Mashhadi Abdolahi, Ramin Rezapour, Ahmed Alboksmaty, Mostafa Farahbakhsh

“…Abstract Background Health Workers Safety (HWS) is a global health priority and essential at all times, in stable situations, in emergencies, in disease epidemics or pandemics. …”
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Do current maternal health staffing and bed occupancy benchmarks work in practice? Results from a simulation model by Giorgia Gon, Carolin Vegvari, Rebecca F Baggaley, Said Mohammed Ali, Salma Abdi Mahmoud, Farhat Jowhar

“…Introduction The WHO has issued the global target of reducing maternal mortality rates by two-thirds of 2010 baseline levels by 2030. …”
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A Step Forward Towards Exploring Nutritional and Biological Potential of Mushrooms: A Case Study of Calocybe gambosa (Fr.) Donk Wild Growing in Serbia by Jovana Dragan Petrovic, Ângela Fernandes, Dejan Stojković, Marina Soković, Lillian Barros, Isabel C.F.R. Ferreira, Aditya Shekhar, Jasmina Glamočlija

“…Edible mushrooms have been appreciated globally for their organoleptic, nutritional and chemical properties. …”
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Phytocompounds from Indonesia Medicinal Herbs as Potential Apelin Receptor Agonist for Heart Failure Therapy: An In-silico Approach by Muhamad Rizqy Fadhillah, Wawaimuli Arozal, Muhammad Habiburrahman, Somasundaram Arumugam, Heri Wibowo, Suci Widya Primadhani, Aryo Tedjo, Surya Dwira, Nurul Gusti Khatimah

“… Heart failure is still a global health problem that demands new pharmacological treatments. …”
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Ultrasound-assisted modification of oat protein isolates: Structural and functional enhancements by Hamad Rafique, Pai Peng, Xinzhong Hu, Kanza Saeed, Muhammad Zubair Khalid, Waseem Khalid, Sonia Morya, Tawfiq Alsulami, Robert Mugabi, Gulzar Ahmad Nayik

“…Escalating global protein demand necessitates the commercialization of protein rich products. …”
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Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS) by Francesca Tonelli, Cecilia Masiero, Carla Aresi, Camilla Torriani, Simona Villani, Guido Premoli, Antonio Rossi, Antonella Forlino

“…Addressing this question represents a need for ensuring global health and wellbeing to all individuals in a world facing the progressive increase of aging and aging related diseases. …”
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The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis by Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred

“…Very low to moderate quality evidence showed that APOE4 carriers benefitted more than APOE4 non-carriers on cognitive (e.g. executive function, learning) and physical (e.g. relative telomere length) outcomes after exercise; and that APOE4 non-carriers benefited over carriers for physical (serum BDNF, gait speed) and cognitive (global cognition, verbal memory) markers. Very low quality evidence indicated that there was no evidence of difference between APOE4 carriers and non-carriers on physical function outcomes in meta-analysis. …”
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Deep learning–based assessment of missense variants in the COG4 gene presented with bilateral congenital cataract by Shaohua Zhang, Yang Sun, Yinghong Ji, Li Ning, Binghe Xiao, Maierdanjiang Ainiwaer, Houyi Liu, Yingying Hong

“…Different pathogenicity metrics were aggregated with principal component analysis (PCA) and further analysed at three levels (amino acid position, substitution and post-translation) based on all possible Cog4 missense variants (n=14 915).Results Localised protein structural impact including change of conformation and amino acid polarity, breakage of hydrogen bond and salt-bridge, and formation of alpha-helix were identified among clinically relevant Cog4 variants. The global structural comparison with multidimensional scaling demonstrated variants with similar protein structures (AF2) tended to exhibit similar clinical and biological phenotypes. …”
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Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation by Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli

“…Objectives Providing adequate access to mental health services is a global challenge. Smartphone apps offer a potentially cost-effective, available and accessible solution for monitoring, supporting and treating mental health conditions. …”
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Ambient PM2.5 Temporal Variation and Source Apportionment in Mbarara, Uganda by Silver Onyango, Crystal M. North, Hatem A. Ellaithy, Paul Tumwesigye, Choong-Min Kang, Vasileios Matthaios, Martin Mukama, Nuriat Nambogo, J. Mikhail Wolfson, Stephen Ferguson, Stephen Asiimwe, Lynn Atuyambe, Data Santorino, David C. Christiani, Petros Koutrakis

“…Abstract Air pollution is the leading environmental cause of death globally, and most mortality occurs in resource-limited settings such as sub-Saharan Africa. …”
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Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation by Ole Christian Hagestad, Lingwei Hou, Jeanette H. Andersen, Espen H. Hansen, Bjørn Altermark, Chun Li, Eric Kuhnert, Russell J. Cox, Pedro W. Crous, Joseph W. Spatafora, Kathleen Lail, Mojgan Amirebrahimi, Anna Lipzen, Jasmyn Pangilinan, William Andreopoulos, Richard D. Hayes, Vivian Ng, Igor V. Grigoriev, Stephen A. Jackson, Thomas D. S. Sutton, Alan D. W. Dobson, Teppo Rämä

“…ABSTRACT Marine fungi remain poorly covered in global genome sequencing campaigns; the 1000 fungal genomes (1KFG) project attempts to shed light on the diversity, ecology and potential industrial use of overlooked and poorly resolved fungal taxa. …”
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Hepatobiliary scintigraphy and liver function changes in patients with hepatocellular carcinoma treated with 166Ho-radioembolization by Margot T.M. Reinders, Maarten J.L. Smits, Karel van Erpecum, Joep de Bruijne, Rutger C.G. Bruijnen, Dave Sprengers, Rob de Man, Erik Vegt, Jan N.M. IJzermans, Marnix G.E.H. Lam, Arthur J.A.T. Braat

“…None of the patients had clinical signs of liver decompensation (Child Pugh ≤ B7, median MELD 9 or ALBI − 2.55). Global and regional hepatic function was based on manual delineation of HBS using 200 MBq 99mTc-mebrofenine, acquired during screening and approximately three months after 166Ho-radioembolization, referred to as liver clearance rate (LCR). …”
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Spatiotemporal variability of groundwater chemistry, source identification and health risks in the southern Chinese Loess Plateau by Zijun Li, Qingchun Yang, Chuan Xie, Hongyun Ma, Bin Wu, Yanli Wang

“…Groundwater pollution of the loess plateau regions has become a global concern due to its vulnerability to natural and anthropogenic influences. …”
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Investigating the production and synergistic antibacterial activity of bacteriocin-like substance from Brevibacillus laterosporus SA-14 (TISTR 2453) for enhanced wound healing by Husna Madoromae, Apichart Atipairin, Malatee Tayeh, Monthon Lertcanawanichakul

“…The rise in antimicrobial-resistant (AMR) bacteria, especially Methicillin-resistant Staphylococcus aureus (MRSA), is a global health concern. Bacteriocins are promising antibiotic alternatives. …”
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Household air pollution exposure and risk of tuberculosis: a case–control study of women in Lilongwe, Malawi by Kenneth Maleta, Robert Krysiak, Irving Hoffman, Sam Phiri, Pamela Jagger, Ryan McCord, Anna Gallerani, Charles Jumbe, Joseph Pedit

“…Introduction Globally, 3–4 billion people rely on solid fuels for cooking, and 1 billion use kerosene to light their homes. …”
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MIGRACIÓN TRABAJADORES RURALES Y CONSTRUCCIÓN SOCIAL DEL TERRITORIO EN EL ALTO VALLE DE RÍO NEGRO by Martha Radonich, Ana Ciarallo, Verónica Trpin, Teresa Vecchia, Silvina Cardelli, Silvina Kopprio, Javier Grosso, Rocio Osorio

“…El espacio del Alto Valle del río Negro históricamente expresó la tensión global–local, dado que desde principios del siglo XX, la actividad frutícola se orientó a la exportación. …”
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Elevated POSTN expression predicts poor prognosis and is associated with radioresistance in cervical cancer patients treated with radical radiotherapy by Cui-qin Huang, Wen-tao Xiao, Xiang-rong Yao, Zhi-min Li, Jun-yan He

“…Abstract Cervical cancer (CC) is a significant global health issue and remains one of the leading causes of cancer-related mortality in women. …”
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Transforming Non-Digital, Clinical Workflows to Detect and Track Vision-Threatening Diabetic Retinopathy via a Digital Platform Integrating Artificial Intelligence: Implementation... by Peranut Chotcomwongse, Paisan Ruamviboonsuk, Chaiwat Karavapitayakul, Koblarp Thongthong, Anyarak Amornpetchsathaporn, Methaphon Chainakul, Malee Triprachanath, Eckachai Lerdpanyawattananukul, Niracha Arjkongharn, Varis Ruamviboonsuk, Nattaporn Vongsa, Pawin Pakaymaskul, Turean Waiwaree, Hathaiphan Ruampunpong, Richa Tiwari, Viroj Tangcharoensathien

“…Abstract Introduction Screening diabetic retinopathy (DR) for timely management can reduce global blindness. Many existing DR screening programs worldwide are non-digital, standalone, and deployed with grading retinal photographs by trained personnel. …”
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Immunogenicity of Two Fractional Inactivated Poliovirus Vaccine Doses vs Single Intramuscular Inactivated Poliovirus Vaccine Dose in Infants of Low- and Middle-income Countries: A... by Kunal Kumar, Sangita Yadav, Raghvendra Singh, Archana Thakur

“…Aims and background: Despite the support of the Global Alliance for Vaccines and Immunization, developing countries still struggle to afford inactivated polio vaccine (IPV). …”
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