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  1. 21521

    Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in <i>Penicillium expansum</i> and <i>Penicillium chrysogenum</i> by Holly P. Bartholomew, Christopher Gottschalk, Bret Cooper, Michael R. Bukowski, Ronghui Yang, Verneta L. Gaskins, Dianiris Luciano-Rosario, Jorge M. Fonseca, Wayne M. Jurick

    Published 2024-12-01
    “…To shed light on this observation, we conducted a comparative genomic, transcriptomic, and metabolomic study of two <i>P. chrysogenum</i> (404 and 413) and two <i>P. expansum</i> (Pe21 and R19) isolates. Global transcriptional and metabolomic outputs were disparate between the species, nearly identical for <i>P. chrysogenum</i> isolates, and different between <i>P. expansum</i> isolates. …”
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  2. 21522

    A Comprehensive Review on Current Knowledge and Future Potential of Topical Therapies in Breast Cancer Treatment by N. Bharathi Sai Thilagam, V.P. Karthik, R. Gnanasambandan, C. Sowmya

    Published 2025-01-01
    “…Breast cancer remains one of the most prevalent malignancies among women globally. Despite advances in therapeutic options, the prognosis often remains challenging. …”
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  3. 21523

    Differential effects of clary sage (Salvia sclarea L.) oil and linalyl acetate on depression levels in diabetic foot ulcer patients with T2DM: a randomized blinded controlled trial by Ji Won Son, Purum Kang, Sun Seek Min, Geun Hee Seol, Geun Hee Seol

    Published 2025-01-01
    “…BackgroundDiabetic foot ulcer (DFU) is a significant global health concern due to its substantial burden on individuals and healthcare systems. …”
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  4. 21524
  5. 21525

    Effectiveness and safety of aripiprazole oral solution in the acute treatment of schizophrenia in Chinese patients by Zhen Mao, Fang Dong, Anning Li, Feng Li, Junhong Zhu, Xiangdong Du, Gang Wu, Huaili Deng, Xueqin Yu, Jintong Liu, Shiping Xie, Xiaowei Tang, Gang Wang

    Published 2024-12-01
    “…The effectiveness endpoints included the Positive and Negative Symptom Scale (PANSS) and the Clinical Global Impression (CGI) scale score. The safety endpoints included adverse events, laboratory inspection indicators (including the serum prolactin level [PRL]), and waist circumferences (WC). …”
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  6. 21526

    Assessment of Nutritional Status in Patients with Head and Neck Cancer Before Radiotherapy: A Single-center, Cross-sectional Study by Susetyowati SUSETYOWATI, Fuadiyah Nila KURNIASARI, Amalia Sarah SHOLIKHATI, Mardiah HARDIANTI, Ericko EKAPUTRA

    Published 2024-03-01
    “…The aim of this research was to assess nutritional status by comparing several parameters, namely anthropometry, biochemistry, physical condition, and inflammatory parameters, with Patient Generated-Subjective Global Assessment (PG-SGA) as the gold standard. Methods: A cross-sectional study with 78 subjects was conducted at the General Hospital Dr. …”
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  7. 21527

    MP-LLAVRec: an agricultural product recommendation algorithm based on LLAVA and user modal preference by Peishan Li, Peishan Li, Peishan Li, Lutao Gao, Lutao Gao, Lutao Gao, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lin Peng, Lin Peng, Lin Peng, Chunhui Bai, Chunhui Bai, Chunhui Bai, Linnan Yang, Linnan Yang, Linnan Yang

    Published 2025-01-01
    “…It consisted of three main components: (1) LLAVA data enhancement, which introduced a multimodal macromodel to improve the understanding of node attributes; (2) agricultural product association relationship fusion, which constructed and improved the complex association network structure among products to ensure that the system can better understand the substitution relationship, complementary relationship, and implied consumption logic among products; (3) user modal preference feature extraction block, which deeply mined the interaction data between consumers and products, and advanced the effective user feature information from the correspondence between global user representations and local modal user representations.Results and DiscussionWe conduct experiments on a real dataset from Amazon's large-scale e-commerce platform to verify the effectiveness of MP-LLAVRec. …”
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  8. 21528

    Drought Adaptation and Responses of Stipa krylovii Vary Among Different Regions: Evidence From Growth, Physiology, and RNA‐Seq Transcriptome Analysis by Ziqing Gong, Zehang Qu, Yulin Liu, Tao Wang, Baijie Fan, Anzhi Ren, Yubao Gao, Nianxi Zhao

    Published 2025-01-01
    “…ABSTRACT In the context of global climate change, exploring how plant adaptation and responses to drought vary among different regions are crucial to understanding and predicting its geographic distribution. …”
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  9. 21529

    Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease by Yuyan Li, Yueming Luo, Yilan Hu, Siting Li, Guandong Li, Wanyangchuan Zhang, Xiufen Gu, Jianting Wang, Shunmin Li, Hong Cheng

    Published 2025-01-01
    “…ObjectiveChronic kidney disease (CKD) is a major global health problem. In clinical practice, the Chinese patent herbal medicine Jianpi-Yishen (JPYS) formula is commonly used to treat CKD. …”
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  10. 21530

    Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

    Published 2025-01-01
    “…BackgroundLeptospirosis is an acute zoonotic disease caused by pathogenic Leptospira, primarily transmitted to humans through contact with water or soil contaminated by the bacteria. It is globally distributed, with heightened prevalence in tropical regions. …”
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  11. 21531

    Integrating wide-swath altimetry data into Level-4 multi-mission maps by M. Ballarotta, C. Ubelmann, V. Bellemin-Laponnaz, F. Le Guillou, G. Meda, C. Anadon, A. Laloue, A. Delepoulle, Y. Faugère, M.-I. Pujol, R. Fablet, G. Dibarboure

    Published 2025-01-01
    “…However, the recent launch of the wide-swath Surface Water Ocean Topography (SWOT) mission in December 2022 marks a significant advancement, enabling the two-dimensional global observation of finer-scale oceanic scales (<span class="inline-formula">∼</span> 15 km). …”
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  12. 21532

    Infections, autoimmunity and immunodeficiencies are the leading etiologies of non-cystic fibrosis bronchiectasis in adults from the southwest of Colombia. by Andrés F. Zea-Vera, Carlos Andrés Rodríguez, Sebastián Giraldo, Mario Alejandro Chacón, Luis Fernando Guerrero, Ricardo Mosquera, Raúl Andrés Vallejo, Fabio Samir Vargas, María Andrea García, María A. Rengifo, Anilza Bonelo, Maximiliano Parra

    Published 2024-12-01
    “…The etiologies of non-cystic fibrosis bronchiectasis in Colombia are diverse, exhibiting notable differences from other global regions. Serum immunoglobulin levels and clinical immunologist consultation should be prioritized in diagnosing patients with unclear bronchiectasis etiology, particularly those with recurrent sinopulmonary infections.…”
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  13. 21533

    Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project by Jonas Pellegrino, Hassen Aziza, Mathieu Guerin, Pascal Taranto, Wenceslas Rahajandraibe, Blaise Ravelo

    Published 2025-01-01
    “…Air pollution is a critical contributor to the global climate change crisis and poses severe threats to human health worldwide. …”
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  14. 21534

    Tracking Immunity: An Increased Number of COVID-19 Boosters Increases the Longevity of Anti-RBD and Anti-RBD-Neutralizing Antibodies by Ching-Wen Hou, Stacy Williams, Veronica Boyle, Alexa Roeder, Bradley Bobbett, Izamar Garcia, Giavanna Caruth, Mitch Magee, Yunro Chung, Douglas F. Lake, Joshua LaBaer, Vel Murugan

    Published 2025-01-01
    “…Background/Objectives: Since the World Health Organization declared COVID-19 a pandemic in March 2020, the virus has caused multiple waves of infection globally. Arizona State University (ASU), the largest four-year university in the United States, offers a uniquely diverse setting for assessing immunity within a large community. …”
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  15. 21535

    RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6 by Lizhe Wang, Yu Wang, Yueyang Li, Li Zhou, Sihan Liu, Yongyi Cao, Yuzhi Li, Shenting Liu, Jiahui Du, Jin Wang, Ting Zhu

    Published 2024-10-01
    “…The molecular processes that propel breast cancer progression are not fully elucidated, highlighting the intricate nature of the underlying biology and its crucial impact on global health. The objective of this research was to perform bioinformatics analyses on breast cancer-related datasets to gain a comprehensive understanding of the molecular mechanisms at play and to identify key genes associated with the disease. …”
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  16. 21536

    Prioritizing Forestation in China Through Incorporating Biogeochemical and Local Biogeophysical Effects by Yu Li, Pengyi Zhang, Huanhuan Wang, Hui Ma, Jie Zhao, Mengyang Xu, Mengyu Wang, Chenhui Guo, Chao Yue

    Published 2024-07-01
    “…Here, we determined priority forestation areas in China by incorporating both effects to maximize its global climate mitigation effect. Our results suggest an additional 167.2 Mha potentially suitable for forestation in China, exceeding the largest forestation target (86.8 Mha) possibly assumed by the government in 2060. …”
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  17. 21537
  18. 21538

    Effects of plant functional group removal on caterpillars (Gynaephora alpherakii) performance and plant production in an alpine meadow by Rui Cao, Han Chen, Jingran Cai, Chen Hang, Ziyu Zhang, Yingchun Miao, Peng Xie

    Published 2025-03-01
    “…Loss of plant functional group diversity has significant repercussions for ecosystem productivity globally. However, our understanding of how this loss of specific functional groups, particularly those providing non-food resources, influences herbivores and, consequently, ecosystem productivity remains limited. …”
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  19. 21539

    Four decades of phenology in an alpine amphibian: trends, stasis, and climatic drivers by Lenzi, Omar, Grossenbacher, Kurt, Zumbach, Silvia, Lüscher, Beatrice, Althaus, Sarah, Schmocker, Daniela, Recher, Helmut, Thoma, Marco, Ozgul, Arpat, Schmidt, Benedikt R.

    Published 2023-01-01
    “…Moreover, we show that changes in phenology, especially in the mountains, can be hard to predict as local microclimatic conditions do not necessarily reflect the observed global climatic trends. …”
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  20. 21540

    Organic Amendments Enhance the Remediation Potential of Economically Important Crops in Weakly Alkaline Heavy Metal-Contaminated Bauxite Residues by Xingfeng Zhang, Qiankui Yu, Bo Gao, Maosheng Hu, Hongxu Chen, Yexi Liang, Haifeng Yi

    Published 2024-12-01
    “…Heavy metal (HM) pollution in soil has emerged as a global concern. This study introduces a novel approach to ameliorate HM-contaminated bauxite residues (BRs) characterized by weak alkalinity and low nutrient levels. …”
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