Changing dynamics of bloodstream infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium in Germany, 2017–2023: a continued burd... by Simon Brinkwirth, Marcel Feig, Ines Noll, Tim Eckmanns, Achim Dörre, Sebastian Haller, Niklas Willrich

“…Abstract Background Antimicrobial resistance is a global threat to public health, with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREfm) being major contributors. …”
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Toxicity effect of Ricinus communis methanolic extracts against Bactrocera cucurbitae (Diptera: Tephritidae) by Sadia Manzoor, Rasheed Akbar, Afaq Hussain, Amjad Ali, Brekhna Faheem, Maid Zaman, Abid Farid, Ijaz Hussain, Imtiaz Ali Khan, Kahkashan Perveen (ORCID:

“…Bactrocera cucurbitae, commonly known as the melon fruit fly, stands as a formidable threat to global agriculture, particularly in the cultivation of cucurbitaceous crops. …”
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Orthopedic Frailty Score and adverse outcomes in patients with surgically managed isolated traumatic spinal injury by Yang Cao, Shahin Mohseni, Babak Sarani, Frank Hildebrand, Ahmad Mohammad Ismail, Maximilian Peter Forssten, Parker Chang, Marcelo A F Ribeiro

“…Background With an aging global population, the prevalence of frailty in patients with traumatic spinal injury (TSI) is steadily increasing. …”
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Symptom network analysis of insomnia-depression-anxiety-stigma in tuberculosis patients by Xiangmin Liu, Xue Qiu, Huizhen Lan, LiuYue Diao, Wei Huang, Yan Wen, Mei Feng, Mei Feng, Xiangdong Tang

“…TRSS1 (family’s negative perception) of the stigma community exhibited the highest betweenness and second highest bridge betweenness in the network, highlighting the mediating role of family support across insomnia and psychological symptoms. Additionally, the global strength invariance test indicates that gender, age and education level do not significantly impact the network structure.ConclusionDepression (anhedonia and sleep problems) and anxiety (nervousness and restlessness) are the primary concerns requiring intervention in TB patients. …”
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LncRNA TUG1 mitigates chronic kidney disease through miR-542-3p/HIF-1α/VEGF axis by Luoxiang Qian, Wanru Hu, Yanping Wang, Yousuf Abdulkarim Waheed, Shuqun Hu, Dong Sun, Shulin Li

“…Ten percent of the adult population in the world suffers from CKD, and as the ageing population continues to rise, it is increasingly regarded as a global threat—a silent epidemic. CKD has been discovered to be closely associated with both long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), while the precise molecular processes behind this relationship are still unclear. …”
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Efficacy of brief intervention for drug misuse in primary care facilities: systematic review and meta-analysis protocol by Toshi A Furukawa, Yan Luo, Norio Watanabe, Ethan Sahker, Masatsugu Sakata, Rie Toyomoto, Chiyoung Hwang, Kazufumi Yoshida

“…Introduction Drug misuse is associated with significant global morbidity, mortality, economic costs and social costs. …”
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High prevalence of fecal carriage of extended-spectrum beta-lactamase producing Enterobacterales among patients with urinary tract infections in rural Tanzania by Magreth Erick Macha, Magreth Erick Macha, Magreth Erick Macha, Weihong Qi, Salome N. Seiffert, Anja Bösch, Philipp Kohler, Honorathy Msami Urassa, Sabine Haller, Erin West, Maja Weisser Rohacek, Maja Weisser Rohacek, Maja Weisser Rohacek, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury

“…IntroductionThe global rise of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) challenges resource-limited countries with insufficient laboratory infrastructure. …”
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Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN-High,” “NE-High,” and “Mixed” by Mintian Cui, Taotao Li, Xinwei Yan, Chao Wang, Qi Shen, Hongbiao Ren, Liangshuang Li, Ruijie Zhang

“…Based on disease activity scores and gene expression data, we defined a global SLE signature and merged three clustering algorithms to develop a single-sample subtype classifier (SSC). …”
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Probe – Integrated electrochemical sensing platform for detection of trace levels of Dapoxetine hydrochloride drug residue in water and drug formulations by H. Alwael, N.A. Asiri, B.G. Alhogbi, A.S. Alharthi, E.A. Bahaidarah, T.N. Abduljabbar, D.F. Baamer, M. Madkour, F.A. Zainy, M.S. El-Shahawi

“…The extensive use and misuse of selective serotonin reuptake inhibitors (SSRIs) in drug formulations has resulted in their accumulation in food sources and environment, posing noteworthy threats to human health and the global economy. Dapoxetine hydrochloride (DPH) is one of the recent oral drugs frequently misused for the treatment of male sexual dysfunction of premature ejaculation and has lately international attention. …”
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Thermal performance enhancement in evacuated tube solar collector with working fluid MWCNT/Al2O3/MgO tri-hybrid nanofluid by Sathish Thanikodi, Jayant Giri, Rathinasamy Saravanan, Shafiq Ahmad, Ahmad O. Hourani

“…This study is motivated-by the urgent global need to enhance the efficiency of solar thermal energy systems, particularly Evacuated Tube Solar Collector (ETSC), to meet the growing demand for renewable energy solutions in combating climate change and reducing reliance on fossil fuels. …”
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Phenolic Compounds and Pharmacological Potential of <em>Lavandula angustifolia</em> Extracts for the Treatment of Neurodegenerative Diseases by Olha Mykhailenko, Viktoriia Hurina, Nataliia Herbina, Yuliia Maslii, Liudas Ivanauskas, Inna Vladymyrova, Dmytro Lytkin, Zigmantas Gudžinskas, Hanna Severina, Olena Ruban, Victoriya Georgiyants

“…Lavender use in Ukraine is influenced by both global herbal practices and local medical traditions. …”
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Trends in tuberculosis mortality among older adults in China, 2004–2021: a Joinpoint regression and age–period–cohort analysis by Mengdi Zhang, Xin Wang, Yiran Xiao, Qiqi Wang, Fei Huang, Xiang Ren, Xiaomin Guo, Wenshan Sun, Jinqi Deng, Qi Jiang, Jianjun Liu, Wenjing Zheng, Hongyan Yao

“…BackgroundTuberculosis (TB) remains a major public health problem in China and globally, particularly among older adults. This study aimed to examine secular trends in TB mortality among older adults in China and the net effects of age, period, and cohort.MethodsData from the National Disease Surveillance Points (DSPs) system were analyzed using Joinpoint regression to determine annual changes in TB mortality among individuals aged 60 years and older from 2004 to 2021. …”
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Multiplexed SSR marker analysis of Diplocarpon coronariae reveals clonality within samples from Middle Europe and genetic distance from Asian and North American isolates by Thomas Oberhänsli, Anna Dalbosco, Virginie Leschenne, Anne Bohr, Sascha Buchleither, Lucius Tamm, Lukas Wille, Srđan G. Aćimović, Fatemeh Khodadadi, Young-Hyun Ryu, Bruno Studer, Hans-Jakob Schärer, Andrea Patocchi

“…Application of the SSR markers to large-scale and diverse Dc samples will help to better understand the epidemiology of AB, which has become a global apple disease, and will help guide effective mitigation strategies based on disease management and resistance breeding.…”
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Advanced artificial intelligence with federated learning framework for privacy-preserving cyberthreat detection in IoT-assisted sustainable smart cities by Mahmoud Ragab, Ehab Bahaudien Ashary, Bandar M. Alghamdi, Rania Aboalela, Naif Alsaadi, Louai A. Maghrabi, Khalid H. Allehaibi

“…Abstract With the fast growth of artificial intelligence (AI) and a novel generation of network technology, the Internet of Things (IoT) has become global. Malicious agents regularly utilize novel technical vulnerabilities to use IoT networks in essential industries, the military, defence systems, and medical diagnosis. …”
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Digital tool as speech and language therapy for patients with post-stroke aphasia by Gerardo Ruiz Ares, Marta Martin Alonso, Ricardo Rigual, Carlos Hervás Testal, Gabriel Torres Iglesias, Laura Casado Fernandez, Elena de Celis Ruiz, Jorge Rodríguez Pardo, Jenny Carvajal Muñoz, Laura González Martín, María Alonso de Leciñana, Blanca Fuentes

“…Aphasia description: Broca's 12 (15.0%), Wernicke's 13 (32.5%), mixed/global 15 (37.5%) cases. Patients began using VerbalizAPP ® 4.8 days (range 2–7) after stroke onset. …”
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Antimicrobial Resistance Profile of E. coli Isolated from Raw Cow Milk and Fresh Fruit Juice in Mekelle, Tigray, Ethiopia by Haftay Abraha Tadesse, Netsenet Berhe Gidey, Kidane Workelule, Hagos Hailu, Seyfe Gidey, Abrha Bsrat, Habtamu Taddele

“…They cause great suffering and are transmitted directly or indirectly between animals and humans and circulate in the global environment. E. coli are among them, causing a major public health problem. …”
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Microstructural modifications in bitumens rejuvenated by oil from pyrolysis of waste tires by Michela Alfe, Valentina Gargiulo, Giovanna Ruoppolo, Francesco Cammarota, Pietro Calandra, Cesare Oliviero Rossi, Valeria Loise, Michele Porto, Roberto Di Capua, Paolino Caputo

“…The impacts of our findings are expected to be extensive because bitumens are globally used for paving roads. In addition, since the proposed method couples/fuses urban waste treatment with asphalt maintenance processes, two types of wastes (oil from pyrolysis of WTs and aged bitumens) can be simultaneously recovered and reused to produce new and performing asphalts.…”
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The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial by Eemil Lehtonen, Maiju Vertanen, Heimo Syvälä, Teemu Tolonen, Seppo Auriola, Teuvo Tammela, Aino Siltari, Teemu Murtola

“…Background: Prostate cancer (PCa) remains a global health burden, with limited reliable biomarkers beyond prostate-specific antigen (PSA). …”
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Large-scale flood risk assessment in data-scarce areas: an application to Central Asia by P. Ceresa, G. Bussi, S. Denaro, G. Coccia, P. Bazzurro, P. Bazzurro, M. Martina, M. Martina, E. Fagà, C. Avelar, M. Ordaz, B. Huerta, O. Garay, Z. Raimbekova, K. Abdrakhmatov, S. Mirzokhonova, S. Mirzokhonova, V. Ismailov, V. Belikov

“…The European Union, in collaboration with the World Bank and the Global Facility for Disaster Reduction and Recovery (GFDRR), created the programme Strengthening Financial Resilience and Accelerating Risk Reduction in Central Asia (SFRARR) to advance disaster and climate resilience in the region. …”
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FeO–alumina catalyst for reforming waste polyethylene terephthalate (PET) pyrolyzed products: synthesis, characterization, and performance evaluation by Audu, Ephraim Akuaden, Ade-Ajayi, Adebola Femi, Osigbesan, Aisha Ayoola, Gano, Zaharaddeen Sani, Barminas, Jeffrey Tsware

“…The growing rate of plastic pollution in Nigeria and across the globe, coupled with the need to harness such waste for useful purposes, is a pressing global concern. In this study, a new type of catalyst was synthesized by incorporating mesoporous FeO onto aluminium oxide trihydrate (alumina) and applied in reforming polyethylene terephthalate (PET) pyrolyzed gas into valuable fuels. …”
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