Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases by Cheng-Cheng Deng, Xue-Yan Xu, Yan Zhang, Long-Can Liu, Xuan Wang, Jun-Yi Chen, Liu-Yi Yao, Ding-Heng Zhu, Bin Yang

“…BackgroundFibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix components. …”
Get full text

Why we need a representative organization of academic PRM in Europe, and why we need it now by Gerold Stucki, Henk J. Stam, Francesca Gimigliano, Stefano Negrini

Get full text

Comparative evaluation of salivary and serum CA 15-3 levels in tobacco users with and without potentially malignant oral disorders (PMOD) and oral squamous cell carcinoma (OSCC) by Gopikrishna Padmanabhan, Ramesh kumar, Rajkumar krishnan, Madhu Narayan, R. Ashwini, Shruthi Venkatkumar

“…Background: The OSCC's prevalence has increased in recent years, which has made it ranked globally as the sixth malignancy and the third-ranked malignancy in Southeast Asia. …”
Get full text

Limited impacts of climatic conditions on commercial oil palm yields in Malaysian plantations by Susannah Fleiss, Colin J. McClean, Henry King, Jane K. Hill

“…Abstract Background Oil palm is a key driver of deforestation, but increasing yields in existing plantations could help meet rising global demands, while avoiding further conversion of natural habitat. …”
Get full text

Performance of deep learning models in predicting the nugent score to diagnose bacterial vaginosis by Naoki Watanabe, Tomohisa Watari, Kenji Akamatsu, Isao Miyatsuka, Yoshihito Otsuka

“…Overall, our findings suggest that deep learning models have the potential to diagnose bacterial vaginosis with an accuracy comparable to that of laboratory technicians.IMPORTANCEBacterial vaginosis is a global health issue affecting women, causing symptoms such as abnormal vaginal discharge and discomfort. …”
Get full text

Aim high, hit ×10: psychological strategies driving the success of South Korean archers by Joonyoung Lee, Suyoung Hwang

“…IntroductionSouth Korean archers have excelled in global competitions. However, limited research exists on the factors contributing to their long-term success, particularly in the context of achieving ×10 scores. …”
Get full text

Stem Cell–Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies by Gabriella Jeanne Mulia, Novelia Anna, John Chung-Che Wu, Hon-Ping Ma, Yung-Hsiao Chiang, Ju-Chi Ou, Kai-Yun Chen

“…Stroke, a neurological condition from compromised cerebral blood perfusion, remains a major global cause of mortality and disability. Conventional therapies like tissue plasminogen activator are limited by narrow therapeutic windows and potential adverse effects, highlighting the urgency for novel treatments. …”
Get full text

Prediction of transcript isoforms and identification of tissue-specific genes in cucumber by Wenjiao Wang, Chengcheng Shen, Xinqiang Wen, Anqi Li, Qi Gao, Zhaoying Xu, Yuping Wei, Yushun Li, Dailu Guan, Bin Liu

“…Abstract Background Identification of global transcriptional events is crucial for genome annotation, as accurate annotation enhances the efficiency and comparability of genomic information across species. …”
Get full text

High-resolution canopy fuel maps based on GEDI: a foundation for wildfire modeling in Germany by Johannes Heisig, Milutin Milenković, Edzer Pebesma

“…We propose a two-step approach where we first use measurements from NASA’s Global Ecosystem Dynamics Investigation (GEDI) instrument to estimate canopy fuel variables at the footprint level, before predicting high-resolution raster maps. …”
Get full text

Development of metastasis and survival prediction model of luminal and non-luminal breast cancer with weakly supervised learning based on pathomics by Hui Liu, Linlin Ying, Xing Song, Xueping Xiang, Shumei Wei

“…Objective Breast cancer stands as the most prevalent form of cancer among women globally. This heterogeneous disease exhibits varying clinical behaviors. …”
Get full text

Dietary Exposure to Aflatoxins in Some Randomly Selected Foods and Cancer Risk Estimations of Cereals Consumed on a Ghanaian Market by Nii Korley Kortei, Theophilus Annan, Seidu A. Richard, Adjoa A. Boakye, Clement O. Tettey, Edward Ken Essuman, Enoch Aninagyei, Precious Agbemeseli

“…It continues to be a major concern in food safety globally. In this study, total and constitutive aflatoxins levels as well as the carcinogenic risks posed by 110 food and feed samples (55 cereals, 20 nuts and oils, 18 animal feed, and 18 fruits and vegetables) collected from the Ho Central market in the Volta region, Ghana, were assessed. …”
Get full text

Numerical Weather Data-Driven Sensor Data Generation for PV Digital Twins: A Hybrid Model Approach by Jooseung Lee, Jimyung Kang, Sangwoo Son, Hui-Myoung Oh

“…With the growing global emphasis on environmental protection policies, renewable energy generation systems have become widely adopted. …”
Get full text

Mendelian randomization analysis of the causal relationship between trimethylamine N-oxide and its precursors and Parkinson’s disease by Bei Zhang, Ruijie Zhang, Huiming Ren, Qiongfeng Guan, Weinv Fan, Liyuan Han

Get full text

Comparative potential of biogas production from the distillery, fruit and vegetable waste and their mixtures (digestion) by Gebresilasie Gebremedhin Gebresilasie, Mulualem G. Gebreslassie, Mebrahtom Gebresemati

“…Biogas is becoming increasingly important as a renewable energy source in the face of global warming and declining fossil fuel reserves. …”
Get full text

Simultaneous Determination of Mineral Nutrients and Toxic Metals in M. stenopetala from Southern Ethiopia: A Comparative Study of Three Cultivating Areas Using MP-AES by Ashenafi Shemnsa, Wondimeneh Dubale Adane, Merid Tessema, Endale Tesfaye, Gizaw Tesfaye

“…As a result, the seeds of M. stenopetala can serve as an alternative source of minerals and play a role in overcoming the current global food crisis, particularly in the dry season. …”
Get full text

Virtual consultation in kidney care: a mixed-methods study on a model for safe and effective integration into routine clinical care by Aminu K Bello, Stephanie Thompson, Deenaz Zaidi, Scott Klarenbach, Feng Ye, Terry J Smith, Mark Courtney

“…Rationale and Objective Globally, the COVID-19 pandemic necessitated a rapid introduction of virtual care delivery via telephone or videoconference. …”
Get full text

Digital Twins and Enabling Technology Applications in Mining: Research Trends, Opportunities, and Challenges by Mihiran Galagedarage Don, Thumeera R. Wanasinghe, Raymond G. Gosine, Peter J. Warrian

Get full text

Spatiotemporal Relationship Between Carbon Metabolism and Ecosystem Service Value in the Rural Production–Living–Ecological Space of Northeast China’s Black Soil Region: A Case Stu... by Yajie Shang, Yuanyuan Chen, Yalin Zhai, Lei Wang

“…Amid global climate challenges and an urgent need for ecological protection, the northeastern black soil region—one of the world’s remaining “three major black soil regions”—confronts significant tensions between agricultural economic development and land ecological protection, threatening national food security. …”
Get full text

Early Diagnosis of Helicobacter pylori Infection in Vietnamese Patients with Acute Peptic Ulcer Bleeding: A Prospective Study by Duc Trong Quach, Mai Ngoc Luu, Toru Hiyama, Thuy-HuongThi To, Quy Nhuan Bui, Tuan Anh Tran, Binh Duy Tran, Minh-Cong Hong Vo, Shinji Tanaka, Naomi Uemura

Get full text

FEATURES OF THE MODEL OF A SPECIALIZED GEOSPATIAL DATABASE FOR VISUALIZING INDICATORS OF HUMAN SOCIO-ECONOMIC SECURITY IN WARTIME CONDITIONS by Zakharii S. Varnalii, Oleksii P. Fedchenko, Ihor V. Pampukha, Ihor V. Tolok

“…Modern geographic information systems, particularly ArcGIS, offer a full range of tools for collecting, organizing, and analyzing geographic data that characterize socio-economic aspects of development at local and global levels. They allow for the creation of effective systems for socio- economic monitoring and decision-making support. …”
Get full text