Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

“…Abstract Liver cancer represents a major global health concern, with projections indicating that the number of new cases could surpass 1 million annually by 2025. …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

“…Background: Malaria remains a significant global health threat, with sub-Saharan Africa (SSA) bearing the highest burden of the disease. …”
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COVID-19 status and utilisation of essential maternal and child healthcare services during the pandemic in Ahmedabad, India by Sandul Yasobant, K Shruti Lekha, Ravina Tadvi, Bhavin Solanki, Walter Bruchhausen, Deepak Saxena

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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“… In the intricate tapestry of human history, the 21st century stands as a chapter marked by the recurring emergence of epidemics, each weaving its unique thread into the fabric of global health. From the haunting reappearances of familiar adversaries like influenza to the unexpected onslaught of novel viruses such as SARS-CoV-2, this era has borne witness to a diverse array of health crises that have tested the resilience of societies worldwide. …”
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Access to water and sanitation among people with disabilities: results from cross-sectional surveys in Bangladesh, Cameroon, India and Malawi by Islay Mactaggart, Hannah Kuper, Sarah Polack, Mahfuzar Rahman, Wolf-Peter Schmidt, Kristof Bostoen, Joseph Chunga, Lisa Danquah, Amal Krishna Halder, Saira Parveen Jolly, Marielle Snel, Adam Biran

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Digital Health Solutions for Cardiovascular Disease Prevention: Systematic Review by Yihan Qi, Emma Mohamad, Arina Anis Azlan, Chenglin Zhang, Yilian Ma, Anqi Wu

“… BackgroundCardiovascular disease (CVD) is a major global health issue, with approximately 70% of cases linked to modifiable risk factors. …”
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Predicting Treatment Outcomes in Patients with Low Back Pain Using Gene Signature-Based Machine Learning Models by Youzhi Lian, Yinyu Shi, Haibin Shang, Hongsheng Zhan

“…Abstract Introduction Low back pain (LBP) is a significant global health burden, with variable treatment outcomes and an unclear underlying molecular mechanism. …”
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Unveiling inequalities: Racial, ethnic, and socioeconomic disparities in diabetes: Findings from the 2007-2020 NHANES data among U.S. adults by Yangyang Deng, Mohammad Moniruzzaman, Breanna Rogers, Lu Hu, Ram Jagannathan, Kosuke Tamura

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Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 by Liping Liu, Anding Xu, Xin Wang, Yongjun Wang, Yilong Wang, Zhongrong Miao, Yuming Xu, Benyan Luo, Bin Peng, Yong Huo, Qiang Dong, Zixiao Li, Xingquan Zhao, Caiyun Wang, Hongqiu Gu, Chunjuan Wang, Zhengqi Lu, Yunyun Xiong, Shuo Wang, Lihua Wang, Linong Ji, Xiaoping Gao, Wenzhi Wang, Yi Yang, Kai Wang, Junbo Ge, Xunming Ji, Jun Pu, Tong Zhang, Bo Hu, Ning Wang, Yun Xu, Jinsheng Zeng, Gang Zhao, Zhong Chen, Aoming Jin, Xiaoyuan Niu, Jiong Shi, Shuya Li, Jianmin Zhang, Ling Yin, Dou Li, Dehong Lu, Chao Qin, Dapeng Sun, Kaifu Ke, Yanhui Du, Xiaoning Zhang, Fudong Shi, Jianxin Zhou, Lan Chu, Li Guo Li He, Shengnian Zhou, Weixin Cai, Xiaomu Wu, Zhiyi He

“…Background Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes. …”
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Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021 by Chengcheng Zhang, Linzhi Chen, Yuqi Xiu, Hongling Zhang, Yuejuan Zhang, Wenjuan Ying

“…BackgroundEsophageal cancer (EC) is a major global health issue characterized by high morbidity and mortality rates, with a notably low five-year survival rate. …”
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Association between early dietary patterns and cardiometabolic health at age 8: a confirmatory analysis of the European Childhood Obesity Project by Mariona Gispert-Llauradó, Joaquin Escribano, Natalia Ferré, Veit Grote, Berthold Koletzko, Gina Ambrosini, Elvira Verduci, Dariusz Gruszfeld, Annick Xhonneux, Veronica Luque

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The forgotten link: how the oral microbiome shapes childhood growth and development by Raymond Rubianto Tjandrawinata, Nurlinah Amalia, Nurlinah Amalia, Nurlinah Amalia, Yosi Yohanes Putra Tandi, Ariq Fadhil Athallah, Caesaroy Afif Wibowo, Muhammad Reva Aditya, Muhammad Reva Aditya, Athaya Rahmanardi Muhammad, Athaya Rahmanardi Muhammad, Maghfira Rahma Azizah, Maghfira Rahma Azizah, Farizky Martriano Humardani, Ammar Nojaid, Jeremy Alvaro Christabel, Alfi Agnuristyaningrum, Fahrul Nurkolis, Fahrul Nurkolis

“…Childhood stunting, defined as impaired linear growth and development, remains a significant global health challenge with long-term consequences on cognitive and physical well-being. …”
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Language and Culture in Health Literacy for People Living with HIV: Perspectives of Health Care Providers and Professional Care Team Members by Keitshokile Dintle Mogobe, Sheila Shaibu, Ellah Matshediso, Motshedisi Sabone, Esther Ntsayagae, Patrice K. Nicholas, Carmen J. Portillo, Inge B. Corless, Carol Dawson Rose, Mallory O. Johnson, Allison Webel, Yvette Cuca, Marta Rivero-Méndez, Solymar S. Solís Báez, Kathleen Nokes, Darcel Reyes, Jeanne Kemppainen, Paula Reid, Lucille Sanzero Eller, Teri Lindgren, William L. Holzemer, Dean Wantland

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The association between tobacco and alcohol use and health outcomes in individuals living with diabetes and prediabetes in South Africa: A cross-sectional study by S J Mulder, T Chivese, C O Egbe

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Health Care Professionals and Data Scientists’ Perspectives on a Machine Learning System to Anticipate and Manage the Risk of Decompensation From Patients With Heart Failure: Quali... by Joana Seringa, Anna Hirata, Ana Rita Pedro, Rui Santana, Teresa Magalhães

“… BackgroundHeart failure (HF) is a significant global health problem, affecting approximately 64.34 million people worldwide. …”
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COPD with Eosinophilic Inflammation is Susceptible to Particulate Air Pollution Exposure by Amja Manullang, Chi-Li Chung, Yueh-Lun Lee, Tzu-Hsuen Yuan, Huan Minh Tran, Firdian Makrufardi, Kian Fan Chung, Kang-Yun Lee, Jer-Hwa Chang, Hsiao-Chi Chuang

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Burden of type 2 diabetes due to high body mass index in different SDI regions and projections of future trends: insights from the Global Burden of Disease 2021 study by Yun-fa Ding, An-xia Deng, Teng-fei Qi, Hao Yu, Liang-ping Wu, Hong-bing Zhang

“…Results The study revealed the significant global health burden of T2DM induced by high BMI, which EAPC of 1.82 with confidence intervals (CI) ranging from 1.78 to 1.87 for disability-adjusted life years (DALYs) and 0.85 with CIs ranging from 0.77 to 0.93 for mortality. …”
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Challenges and support factors in managing type 2 diabetes among pregnant women in Thailand: A convergent mixed-methods study by Ratchanok Phonyiam, Chiao-Hsin Teng, Catherine Sullivan, Aunchalee Palmquist, Eric Hodges, Yamnia Cortés, Marianne Baernholdt

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Co-producing a safe mobility and falls informatics platform to drive meaningful quality improvement in the hospital setting: a mixed-methods protocol for the insightFall study by Ben Glampson, Clare Leon-Villapalos, Erik Mayer, Rachael Lear, Phoebe Averill, Catalina Carenzo, Rachel Tao, Robert Latchford

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Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd by Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Mohammed Mostafa Al Quadir, Mst Rubaiat Nazneen Akhand, Mohammad Mehedi Hasan Khan

“…Antibiotic-resistant bacteria are becoming increasingly common, leading to a global health crisis. The effects of abusing antibiotics not only increase pathogenic resistance but also cause various diseases and syndromes. …”
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