Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials by Tao Zeng, Lei Li, Yan Zhou, Liang Gao

“…Gliomas are primary brain tumors presumably derived from glial cells. …”
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Tight junction proteins in glial tumors development and progression by Jakub Moskal, Slawomir Michalak, Slawomir Michalak

“…Claudins are involved in tumorigenesis processes that lead to glioma formation. In gliomas, there is a noticeable dysregulation of claudins, occludin, and zonula occludens-1 abundance, and their dislocation has been observed. …”
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Management of Congenital Midline Nasofrontal Masses: Case Report and Review of Literature by A. C. Volck, G. A. Suárez, A. J. Tasman

“…Epidermoid cysts, dermoids, gliomas, and meningo-/encephaloceles are the most important differential diagnoses in congenital nasofrontal masses. …”
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When the Stomach Pain Is Literally “In Your Head” by D. Jakubauskas, M. Sarafinaitė, R. Mameniškienė

“…Temporal lobe epilepsy often has no clear cause, although it may be associated with diseases such as temporal lobe sclerosis, dysembryoplastic neuroepithelial tumours, and other benign tumours, as well as arterio-venous malformations, gliomas, defects in neuronal migration, or lesions of the cortex caused by encephalitis. …”
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Multiple Extracranial Metastases from Primary Gliosarcoma in a Patient with Two Previous Different Primary Cancers by T. Capion, J. Hauerberg, H. Broholm, A. Muhic

“…Despite the fact that malignant gliomas are highly invasive, extracranial metastases are very rarely seen, and the mechanisms behind extracranial dissemination are still unclarified. …”
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The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas by Elias A. El Habr, Christos Adamopoulos, Georgia Levidou, Aggeliki A. Saetta, Penelope Korkolopoulou, Christina Piperi

“…Astrocytomas, the most common type of gliomas, and especially grade IV glioblastomas are “endowed” with strong proliferation and invasion potentials, high recurrence rate, and poor patients' prognosis. …”
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Current Trends in Targeted Therapies for Glioblastoma Multiforme by Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

“…Glioblastoma multiforme (GBM) is one of the most frequently occurring tumors in the central nervous system and the most malignant tumor among gliomas. Despite aggressive treatment including surgery, adjuvant TMZ-based chemotherapy, and radiotherapy, GBM still has a dismal prognosis: the median survival is 14.6 months from diagnosis. …”
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PPARs in Human Neuroepithelial Tumors: PPAR Ligands as Anticancer Therapies for the Most Common Human Neuroepithelial Tumors by Elisabetta Benedetti, Renato Galzio, Barbara D'Angelo, Maria Paola Cerù, Annamaria Cimini

“…This review will focus on the major studies dealing with PPAR expression in gliomas and neuroblastoma and the therapeutic implications of using PPAR agonists for the treatment of these neoplasms.…”
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A Case of Congenital Brainstem Oligodendroglioma: Pathology Findings and Review of the Literature by Stefan Kostadinov, Suzanne de la Monte

“…Herein, we report an unusual case of congenital anaplastic oligodendroglioma that arose in the pons and was detected as diffuse pontine glioma on in utero imaging studies during prenatal evaluation at 26 weeks’ gestation. …”
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Surgical Management of Pilocytic Astrocytoma of the Optic Nerve: A Case Report and Review of the Literature by Ifeoluwa Apanisile, Tamás Karosi

“…Optic nerve astrocytomas (ONAs) are frequent types of optic nerve gliomas (ONGs), which can affect the visual pathway. …”
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Clinical Significance of NKD Inhibitor of WNT Signaling Pathway 1 (NKD1) in Glioblastoma by Lijun Li, Ruiying Gao, Weizhong Huangfu, Fang Zhang, Ruixia Wang

“…As the most malignant type of gliomas, glioblastoma is characterized with disappointing prognosis. …”
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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells by Katarína Smolková, Petr Ježek

“…Arg172 mutants of human IDH2—frequently found with similar mutants of cytosolic IDH1 in grade 2 and 3 gliomas, secondary glioblastomas, and acute myeloid leukemia—catalyze reductive carboxylation of 2-oxoglutarate and reduction to D-2-hydroxyglutarate, which strengthens the neoplastic phenotype by competitive inhibition of histone demethylation and 5-methylcytosine hydroxylation, leading to genome-wide histone and DNA methylation alternations. …”
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Primary Gliosarcoma of the Cerebellum in a Young Pregnant Woman: Management Challenges and Immunohistochemical Features by Marco Meloni, Salvatore Serra, Giulia Bellisano, Nikolaos Syrmos, Sanjeeva Jeyaretna, Mario Ganau

“…Similar to other high-grade gliomas, GS affects mainly adults in the 5th-7th decade of life and presents a higher incidence in males. …”
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Immunotherapy of Brain Cancers: The Past, the Present, and Future Directions by Lisheng Ge, Neil Hoa, Daniela A. Bota, Josephine Natividad, Andrew Howat, Martin R. Jadus

“…Treatment of brain cancers, especially high grade gliomas (WHO stage III and IV) is slowly making progress, but not as fast as medical researchers and the patients would like. …”
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A Co-Evolutionary Genetic Algorithm Approach to Optimizing Deep Learning for Brain Tumor Classification by Abdelmgeid A. Ali, Mohamed T. Hammad, Hassan S. Hassan

“…Specifically, we utilize EfficientNetB3 and DenseNet121 pre-trained models in conjunction with the Co-Evolutionary Genetic Algorithm (CEGA) to classify brain tumors into four categories: gliomas, meningiomas, pituitary adenomas, and no tumors. …”
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Image and Histologic Characterization of Intracranial Neoplasias by Martha Yudey Rodríguez Pino, Dianarelys Villafuerte Delgado, Thaimí Conde Cueto, Odalys Yanes Isray, Adelaida Martínez Godoy, Carlos Rafael Rivera Prieto

“…The tomographic diagnosis coincided with the histological one in 85,7 % of gliomas, in 80 % of meningiomas and in 40 % of metastases. …”
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Context aware machine learning techniques for brain tumor classification and detection – A review by Usman Amjad, Asif Raza, Muhammad Fahad, Doaa Farid, Adnan Akhunzada, Muhammad Abubakar, Hira Beenish

“…Background: Machine learning has tremendous potential in acute medical care, particularly in the field of precise medical diagnosis, prediction, and classification of brain tumors. Malignant gliomas, due to their aggressive growth and dismal prognosis, stand out among various brain tumor types. …”
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Immunohistochemical Profile of p62/SQSTM1/Sequestosome-1 in Human Low- and High-Grade Intracranial Meningiomas by Antonio Ieni, Cristina Pizzimenti, Vincenzo Fiorentino, Mariausilia Franchina, Antonino Germanò, Giovanni Raffa, Maurizio Martini, Guido Fadda, Giovanni Tuccari

“…Although, recently, p62 expression has been analyzed in different neurodegenerative and glial neoplastic diseases, no available information have been reported in meningiomas, which have an high epidemiological relevance being the second most common category of intracranial tumors after gliomas. Generally meningiomas have a benign behavior, but their recurrence is not uncommon mainly when atypical or anaplastic varieties occur. …”
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Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4 by Zhe Huang, Ming Wang, Yitian Chen, Hua Tang, Kuo Tang, Mingkuan Zhao, Wei Yang, Zhengjun Zhou, Junjie Tian, Wei Xiang, Shenjie Li, Qinglian Luo, Luotong Liu, Yanru Zhao, Tao Li, Jie Zhou, Ligang Chen

“…Abstract Almost all high-grade gliomas, particularly glioblastoma (GBM), are highly migratory and aggressive. …”
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Improved Outcomes with Intensity Modulated Radiation Therapy Combined with Temozolomide for Newly Diagnosed Glioblastoma Multiforme by Noel J. Aherne, Linus C. Benjamin, Patrick J. Horsley, Thomaz Silva, Shea Wilcox, Julan Amalaseelan, Patrick Dwyer, Abdul M. R. Tahir, Jacques Hill, Andrew Last, Carmen Hansen, Craig S. McLachlan, Yvonne L. Lee, Michael J. McKay, Thomas P. Shakespeare

“…Intensity modulated radiation therapy (IMRT) is gaining widespread acceptance in other tumour sites, although evidence to support its use over three-dimensional conformal radiation therapy (3DCRT) in the treatment of gliomas is currently lacking. We examined the survival outcomes for patients with GBM treated with IMRT and Temozolomide. …”
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