Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment by Yifu Shu, Jing Li

“…Immune infiltration was assessed via ssGSEA, while transwell assays and immunofluorescence examined the effects of disulfidptosis-Tex genes on glioma cell behavior and immune response.ResultsEleven disulfidptosis-Tex genes were found critical for glioblastoma survival outcomes. …”
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Improved Excitation Light Rejection Enhances Small-Animal Fluorescent Optical Imaging by Kildong Hwang, Jessica P. Houston, John C. Rasmussen, Amit Joshi, Shi Ke, Chun Li, Eva M. Sevick-Muraca

“…The addition of collimating optics resulted in a 51% to 75% reduction in the ratio of ( S (Λ x ))/( S (Λ m )– S (Λ x )) for the phantom studies and an improvement of TBR from 11% to 31% and of signal-to-noise ratio from 11% to 142% for an integrin-targeting conjugate in human glioma xenografts.…”
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Tumour-Associated Transcripts and EGFR Deletion Variants in Colorectal Cancer in Primary Tumour, Metastases and Circulating Tumour Cells by Silke Lankiewicz, Eva Rother, Silke Zimmermann, Christiane Hollmann, Firouzeh Korangy, Tim F. Greten

“…Besides, detailed expression profiling of EGFR variants in various colorectal and glioma cell lines has been performed to generate positive controls, resulting in the discovery of two new transcript deletion variations (cEX12_15del, cEX12_14del) located on the extracellular domain of the EGFR.…”
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IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression by Qianting Tian, Guixue Dan, Xuyan Wang, Jiamei Zhu, Chaochun Chen, Dekun Tang, Ziming Wang, Dan Chen, Shan Lei, Chao Yang, Houmei Wang, Bing Guo, Bangming Jin, Tengxiang Chen, Lei Tang

“…Here, we showed that the expression of IDO1 was markedly increased in patients with glioma and associated with GBM progression. IDO1 overexpression suppressed ferroptotic cell death, reduced ROS and lipid peroxide generation in GBM cells. …”
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A Patient with Double-Negative VGKC, Peripheral Nerve Hyperexcitability, and Central Nervous System Symptoms: A Postinfectious Autoimmune Disease by Birte Eikeland

“…Research in the last few years has indicated that most voltage-gated potassium channel- (VGKC-) complex antibodies without leucine-rich glioma-inactivated protein 1 or contactin-associated protein-like 2 antibody specificity lack pathogenic potential and are not clear markers for autoimmune inflammation. …”
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Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities by Jiarui Zhang, Jinan Zhang, Chen Yang

“…Autophagy can control the advancement of different types of brain tumors like glioblastoma, glioma, and ependymoma, demonstrating its potential for treatment. …”
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Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance by Alessia Fidoamore, Loredana Cristiano, Andrea Antonosante, Michele d’Angelo, Erica Di Giacomo, Carlo Astarita, Antonio Giordano, Rodolfo Ippoliti, Elisabetta Benedetti, Annamaria Cimini

“…Among all solid tumors, the high-grade glioma appears to be the most vascularized one. In fact, “microvascular hyperplasia” is a hallmark of GBM. …”
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Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR by Aixin Yu, Yiqi Wang, Chao Duan, Jun Qin, Miaomiao Liao, Haiyan Zhu, Junrong Lei, Jun Liu, Zehao Yang, Li Yu, Hui Gui, Jinxin Xin, Weiwei Tao, Wendai Bao, Zhiqiang Dong

“…Clinical data demonstrate circPLOD2a and b are highly expressed in GBM negatively correlated with XIRP1, whose lower expression associates with higher glioma grade and worse prognosis. In conclusion, hypoxia-induced circPLOD2a and b are oncogenic regulators of tumour aggressiveness through attenuating the interaction between HuR and XIRP1 in glioblastoma cells and may be potential therapeutic targets for this disease.…”
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Intracranial Gliofibroma: A Case Report and Review of the Literature by Patricia Gargano, Graciela Zuccaro, Fabiana Lubieniecki

“…These findings of a glial component with collagenous stroma were consistent with a desmoplastic glioma. Because of the rarity of this entity, we believe it is important to report every case in order to adequately analyze and categorize the tumor in the next WHO classification.…”
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Rituximab for Autoimmune Encephalitis with Epilepsy by Mohankumar Kurukumbi, Rahul H. Dave, Jose Castillo, Tulsi Shah, Joanne Lau

“…It is characterized by antibodies against cerebral antigens, such as potassium channels such as leucine-rich, glioma inactivated 1 (LGI1) and contactin-associated protein 2 (CASPR2), calcium channels such as the voltage-gated calcium channel (VGCC), or neurotransmitter receptors such as the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), gamma aminobutyric acid receptor (GABAR), and N-methyl-D-aspartate receptor (NMDAR). …”
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Effect of Arginine Vasopressin on Intraoperative Hypotension Caused by Oral Administration of 5-Aminolevulinic Acid by Gen Owada, Hideo Nishizawa, Yuki Matoyama, Eri Watanabe, Keigo Mitsuda, Naoki Kaneko, Yasuhiro Kimura, Taikan Nanao, Junichi Fujimoto

“…A 77-year-old man scheduled for a craniotomy for glioma was administered 5-ALA orally before surgery. …”
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Infantile (congenital) anaplastic intracranial solitary fibrous tumor/hemangiopericytoma—A case report with brief literature review by Mohapatra Debahuti, Lenka Anasuya, Deo R. Chandra, Das Prateek

“…The magnetic resonance imaging (MRI) showed a space-occupying lesion measuring 8.2 cm × 7 cm × 6.9 cm in the fronto-temporo-parietal region with a clinical diagnosis of glioma/atypical teratoid rhabdoid tumor (ATRT). The microscopy revealed a spindle cell tumor arranged in a patternless pattern with variable cellularity, increased mitosis, and areas of coagulative necrosis. …”
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PBVit: A Patch-Based Vision Transformer for Enhanced Brain Tumor Detection by Pratikkumar Chauhan, Munindra Lunagaria, Deepak Kumar Verma, Krunal Vaghela, Ghanshyam G. Tejani, Sunil Kumar Sharma, Ahmad Raza Khan

“…Brain Tumor holds a significant holds in human health, classified into three primary types: glioma, meningioma, and pituitary tumors. Early detection and accurate classification are vital for effective diagnosis and lowering healthcare costs. …”
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Extended depth-of-field microscopic imaging for intact histological samples via self-calibrated diplane network by Yuezhi He, Xu Yang, Shiwei Ye, Zonghua Wen, Peng Liu, Hui Li, Feng Xiang, Jiuling Liao, Yizhou Tan, Haoyong Ning, Junjie Zou, Guilu He, Long Zeng, Yanwu Guo, Hui Li, Ying Gu, Bo Wang, Wei Zheng

“…By incorporating the diplane network into a custom-made vacuum compression device, intact and unprocessed mouse brain and human glioma samples are imaged. The results show that DE-DRUM captures pathological features across highly uneven tissue surfaces. …”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma. by Haofei Wang, Zhen Liu, Zesheng Peng, Peng Lv, Peng Fu, Xiaobing Jiang

“…We assessed cell proliferation, migration, and invasion capabilities through in vitro assays (including CCK-8, Edu, wound healing, and transwell assays) and quantitatively analyzed TSPAN13 expression levels in clinical glioma samples using tissue microarray immunohistochemistry. …”
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Enhanced Brain Tumor MRI Classification Using Stationary Wavelet Transform, ResNet50V2, and LSTM Networks by Oussama Abda, Hilal NAIMI

“…After that a Long Short Term Memory network receives the features. that will model the dependencies in the feature space and classifies into four categories: Glioma, Meningioma, Pituitary tumors, and No Tumor. …”
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Ensemble Deep Learning Technique for Detecting MRI Brain Tumor by Rasool Fakhir Jader, Shahab Wahhab Kareem, Hoshang Qasim Awla

“…The classification process of MRI (magnetic resonance imaging) is frequently used for making medical diagnoses for conditions including pituitary, glioma, meningioma, and no tumor. For this reason, determining the type of MRI and its quantity are significant and valuable measurements that reveal the brain’s state of health. …”
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Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach by Amir Taherkhani, Parita Khodadadi, Lida Samie, Zahra Azadian, Zeynab Bayat

“…Mitogen-activated protein kinase 3 (MAPK3) mediates the onset, progression, metastasis, drug resistance, and poor prognosis in various malignancies, including glioma, liver, ovarian, thyroid, lung, breast, gastric, and oral cancers. …”
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An MR Brain Images Classifier System via Particle Swarm Optimization and Kernel Support Vector Machine by Yudong Zhang, Shuihua Wang, Genlin Ji, Zhengchao Dong

“…The abnormal brain MR images consist of the following diseases: glioma, metastatic adenocarcinoma, metastatic bronchogenic carcinoma, meningioma, sarcoma, Alzheimer, Huntington, motor neuron disease, cerebral calcinosis, Pick’s disease, Alzheimer plus visual agnosia, multiple sclerosis, AIDS dementia, Lyme encephalopathy, herpes encephalitis, Creutzfeld-Jakob disease, and cerebral toxoplasmosis. …”
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Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival by Sandra Bien-Möller, Ellen Balz, Susann Herzog, Laura Plantera, Silke Vogelgesang, Kerstin Weitmann, Carolin Seifert, Matthias A. Fink, Sascha Marx, Angela Bialke, Chitra Venugopal, Sheila K. Singh, Wolfgang Hoffmann, Bernhard H. Rauch, Henry W. S. Schroeder

“…Patients with glioblastoma multiforme (GBM) are at high risk to develop a relapse despite multimodal therapy. Assumedly, glioma stem cells (GSCs) are responsible for treatment resistance of GBM. …”
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