Valproic acid targets IDH1 mutants through alteration of lipid metabolism by Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum

“…Both VPA and a selective FASN inhibitor TVB-2640 rewired the lipidome and promoted apoptosis in an IDH1 MT but not in an IDH1 WT glioma cell line. We further find that HDACs are involved in the regulation of lipogenic genes and HDAC6 is particularly important for the regulation of FASN in IDH1 MT glioma. …”
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Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients by Emre LEVENTOGLU, Gurses SAHIN, Sule YESIL, Ceyhun BOZKURT, Nazmiye YUKSEK, Ali FETTAH, Sule TOPRAK, Burcak KURUCU BILGIN, Emre CAPKINOGLU, Nilgun EROGLU, Sibel AKPINAR TEKGUNDUZ, Ayse Ulya ERTEM

“…IDH1 and IDH2 mutations have been found in many types of cancer, such as malignant gliomas, acute myeloid leukemias, chondrosarcoma, and thyroid carcinoma. …”
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Circular RNA circFGFR1 Functions as an Oncogene in Glioblastoma Cells through Sponging to hsa-miR-224-5p by Qian Zhang, Shan Chen, Yingwei Zhen, Peng Gao, Zhenyu Zhang, Hao Guo, Yong Wang

“…Here, we state that circFGFR1 is elevated in glioma cells, resulting in aggravated glioma aggravated malignancy. …”
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Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment. by Yajia Chen, Jingxian Zhang, Weiqian Zheng, Hongwu Xu

“…Despite the availability of various treatment options, glioblastoma (GBM) remains an extremely aggressive form of glioma with a poor prognosis. In recent studies, regulatory cell death (RCD) has been identified as an effective mechanism to suppress glioma. …”
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Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child by Y. T. Udaka, K. Shayan, N. A. Chuang, J. R. Crawford

“…This case illustrates the diverse presentation of ATRT in childhood that can clinically and radiographically mimic that of low grade glioma.…”
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Comparative proteomic analysis of astrocytoma tissues from patients with and without seizures by Thanakorn Khaosuwan, Kittinun Leetanaporn, Pongsakorn Choochuen, Raphatphorn Navakanitworakul, Anukoon Kaewborisutsakul, Thara Tunthanatip, Surasak Sangkhathat, Wararat Chiangjong, Kanitpong Phabphal

“…Abstract Astrocytoma is a common type of glioma and a frequent cause of brain tumour-related epilepsy. …”
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Analysis of Wave Solutions of an Adhenovirus-Tumor Cell System by Baba Issa Camara, Houda Mokrani

“…We discuss biological background and mathematical analysis of glioma gene therapy for contributing to cancer treatment. …”
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The Temporal Pattern of a Lesion Modulates the Functional Network Topology of Remote Brain Regions by W. De Baene, G. J. M. Rutten, M. M. Sitskoorn

“…In this study, we compared resting-state functional connectivity data of patients with a slowly growing low-grade glioma (LGG) with that of patients with a faster-growing high-grade glioma (HGG). …”
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FDA-approved kinase inhibitors: a promising therapeutic avenue for traumatic brain injury by Dezhu Gao, Yu Shi, Zhiliang Wang, Weiming Liu

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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

“…Significant downregulation of SOX2 expression was observed in colorectal adenocarcinoma, esophageal carcinoma, rectum adenocarcinoma, stomach adenocarcinoma, and testicular germ cell tumors, whereas its expression was upregulated in cervical squamous cell carcinoma, glioblastoma multiforme, lower grade glioma, lung adenocarcinoma, and lung squamous cell carcinoma.Survival analysis showed that low SOX2 expression correlated with better prognosis in bladder cancer, liver hepatocellular carcinoma, kidney renal clear cell carcinoma, and sarcoma, whereas high SOX2 expression was associated with poor prognosis in lung adenocarcinoma, and lung squamous cell carcinoma, glioblastoma multiforme, lower grade glioma. …”
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Self-Assembly Iron Oxide Nanoclusters for Photothermal-Mediated Synergistic Chemo/Chemodynamic Therapy by Xiang Li, Zhen Wang, Mian Ma, Zhouqing Chen, Xiang-long Tang, Zhong Wang

“…Our SPIOCs@HSA-RGD nanoplatform showed well biocompatibility and could target glioma specifically. Photothermal conversion and ROS burst were detected after continuous 808 nm light irradiation, and a significant antitumor effect was achieved. …”
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Association between a Primitive Brain Tumor and Cerebral Aspergillosis by Siegfried Hélage, Charles Duyckaerts, Danielle Seilhean, Jean-Jacques Hauw, Jacques Chiras

“…A case of lethal cerebral aspergillosis in a patient with an infiltrative glioma treated with corticotherapy and radiotherapy is reported. …”
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Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway by Laura Giannotti, Benedetta Di Chiara Stanca, Francesco Spedicato, Daniele Vergara, Eleonora Stanca, Fabrizio Damiano, Luisa Siculella

“…In this study, we treated U87MG glioma cells with low dose (1 μM) CBD and evaluated its molecular effects. …”
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Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature by Gene M. Weinstein, Knarik Arkun, James Kryzanski, Michael Lanfranchi, Gaurav K. Gupta, Harprit Bedi

“…Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. …”
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Changes in the organ of vision in neurofibromatosis type 1 in the developmental age by Mirosława Grałek, Katarzyna Piasecka, Katarzyna Wasyliszyn-Sieroszewska, Anna Niwald

“…Ocular manifestations mainly present as eyelid abnormalities due to hamartomas, Lisch nodules on the iris, optic glioma, and glaucoma. Diagnostics relies on clinical and imaging evaluations, as well as genetic testing. …”
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The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer by Xiaosi Gu, Xin Hu, Sijia Zhang, Xiaoyu Zhang, Yong Wang, Lianlian Li, Lianlian Li

“…This review summarizes the clinical significance of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis and outlines the function and molecular regulation mechanism of HOXC13-AS in various types of cancer, including nasopharyngeal carcinoma, breast cancer, oral squamous cell carcinoma, glioma, and cervical cancer. Overall, this review emphasizes the potential of HOXC13-AS as a human tumor predictive biomarker and therapeutic target, paving the way for its clinical application.…”
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Temozolomide-Induced Myelodysplasia by Ethan A. Natelson, David Pyatt

“…A patient who had received temozolomide (TMZ) as a single agent in treatment of malignant glioma developed therapy-induced myelodysplasia (T-MDS). …”
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Pilocytic astrocytoma: A rare case report by Harry Galuh Nugraha, PhD, Elsa Yoasta, MD, Mirna Sobana, MD, Hermin Aminah Usman, MD

“…Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. …”
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Anti-LGI1 antibody autoimmune encephalitis. Clinical case presentation and literature review by A. Stašaitytė, T. Vanagas, V. Danielius, G. Jurkevičienė, R. Balnytė

“… Anti-leucine-rich glioma inactivated 1 (anti-LGI1) encephalitis is a rare autoimmune limbic encephalitis. …”
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Reoperation as a Result of Raised Intracranial Pressure Associated with Cyst Formation in Tumor Cavity after Intracranial Tumor Resection: A Report of Two Cases by Jinlu Yu, Wenji Xiong, Limei Qu, Haiyan Huang

“…We report two cases of reoperation as a result of raised ICP associated with cyst formation in the tumor resection cavity, one arising after glioma resection and the other after meningioma resection. …”
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