Essential Oils from Citrus Peels Promote Calcium Overload-Induced Calcicoptosis in U251 Cells by Yurong Li, Juanjuan Wei, Zimao Ye, Chen Ji, Wenji Li, Li Xu, Zhiqin Zhou

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Quantitative Physiologic MRI Combined with Feature Engineering for Developing Machine Learning-Based Prediction Models to Distinguish Glioblastomas from Single Brain Metastases by Seyyed Ali Hosseini, Stijn Servaes, Brandon Hall, Sourav Bhaduri, Archith Rajan, Pedro Rosa-Neto, Steven Brem, Laurie A. Loevner, Suyash Mohan, Sanjeev Chawla

Subjects: “…glioblastomas…”
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Systemic brain dissemination of glioblastoma requires transdifferentiation into endothelial-like cells via TGF-β-ALK1-Smad1/5 signaling by Thomas M.B. Ware, Adilson Fonseca Teixeira, Josephine Iaria, Rodney B. Luwor, Hong-Jian Zhu

Subjects: “…Glioblastoma…”
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Comparative Cytotoxic Activity of Wild Harvested Stems and In Vitro-Raised Protocorms of Dendrobium chryseum Rolfe in Human Cervical Carcinoma and Glioblastoma Cell Lines by Bijaya Pant, Pusp Raj Joshi, Sabitri Maharjan, Laxmi Sen Thakuri, Shreeti Pradhan, Sujit Shah, Sven H. Wagner, Basant Pant

“…The comparative cytotoxic activities of the wild and in vitro-raised protocorms were evaluated in human cervical carcinoma (HeLa) and human glioblastoma (U251) cell lines by MTT assay. In in vivo and in vitro, the methanol extracts of D. chryseum showed significant cytotoxic activities. …”
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C-Methionine Positron Emission Tomographic Imaging of Biologic Activity of a Recurrent Glioblastoma Treated with Stereotaxy-Guided Laser-Induced Interstitial Thermotherapy by Norbert Galldiks, Wernholt von Tempelhoff, Deniz Kahraman, Lutz W. Kracht, Stefan Vollmar, Gereon R. Fink, Michael Schroeter, Roland Goldbrunner, Matthias Schmidt, Mohammad Maarouf

“…In patients with recurrent glioblastoma multiforme (GBM), local minimally invasive treatment modalities have gained increasing interest recently because they are associated with fewer side effects than open surgery. …”
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Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis by Feng Si, Qian Wang, Fei Chen, Xiangdong Lu

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Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats by Sepide Nateghi, Ameneh Rezayof, Fatemeh Kouhkan, Ladan Delphi, Yavar Bagheri Davisaraei, Fatemeh Rostami, Fatemeh Tirgar, Houri Sepehri

“…The present study investigated the impact of GABAergic signaling and miRNA expression on glioblastoma multiforme (GBM) growth within the medial prefrontal cortex (mPFC) and its associated cognitive and emotional impairments. …”
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Associated adverse outcomes with tumor treating fields when combined to temozolomide versus temozolomide alone for the treatment of glioblastoma: a meta-analysis of randomized trials by Yuanyuan Chen, Yan Chen, Hong Zhen, Danhua Lou

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Editorial: New insights into intracellular pathways and therapeutic targets in CNS diseases by Lisa Gherardini

Subjects: “…glioblastoma (GBM)…”
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99mTc(CO)3-Labeled 1-(3-Nitropyridin-2-yl) Piperazine as Potential Radioligand for 5-HT7 Receptors by Sajjad Molavipordanjani

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Neoadjuvant anti-PD1 immunotherapy for surgically accessible recurrent glioblastoma: clinical and molecular outcomes of a stage 2 single-arm expansion cohort by J. Ricardo McFaline-Figueroa, Lu Sun, Gilbert C. Youssef, Raymond Huang, Gang Li, Jiyoon Kim, Eudocia Q. Lee, Lakshmi Nayak, Ugonma Chukwueke, Rameen Beroukhim, Tracy T. Batchelor, E. Antonio Chiocca, Richard G. Everson, Lisa Doherty, Jennifer Stefanik, Kathryn Partridge, Amanda Spearman, Alexa Myers, Catharina Westergaard, Alyssa Russ, Maria Lavallee, Anna Smokovich, Corey LaForest-Roys, Rachel Garcia Fox, Christine McCluskey, Wenya Linda Bi, Omar Arnaout, PierPaolo Peruzzi, G. Rees Cosgrove, Keith L. Ligon, Isabel Arrillaga-Romany, Jennifer L. Clarke, David A. Reardon, Timothy F. Cloughesy, Robert M. Prins, Patrick Y. Wen

“…Abstract Glioblastoma is immunologically “cold” and resistant to single-agent immune-checkpoint inhibitors (ICI). …”
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Exosomal miR-21-5p from glioma associated mesenchymal stem cells promotes the progression and glycolysis of glioblastoma via PDHA1 by Yanbin Zhang, Peng Lv, Qing Zhang, Wei Xiang, Xiaobing Jiang, Zijun Guo, Tao Zhang

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Peer Review of “Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy for Recurrent Glioblastoma: An Augmented Meta-Analysis of Phase 1 Clinical Trials (Preprint)” by Vanessa Fairhurst, Randa Salah Gomaa Mahmoud, Toba Olatoye, Sylvester Sakilay

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Oncolytic reprogramming of tumor microenvironment shapes CD4 T-cell memory via the IL6ra-Bcl6 axis for targeted control of glioblastoma by Jeffrey M. Grimes, Sadashib Ghosh, Shamza Manzoor, Li X. Li, Monica M. Moran, Jennifer C. Clements, Sherrie D. Alexander, James M. Markert, Jianmei W. Leavenworth

“…Here we report that CD4+ T cells are required for durable tumor control in syngeneic murine models of glioblastoma multiforme after treatment with an oncolytic herpes simplex virus (oHSV) engineered to express IL-12. …”
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Case report: A rare case of a long-term survivor of glioblastoma who underwent two courses of hypofractionated radiotherapy as part of her care by Midhad Mrvoljak, Midhad Mrvoljak, Shubhendu Mishra, Liam Chen, Liam Chen, Elizabeth Neil, Elizabeth Neil, Eric Ehler, Stephanie Terezakis, Stephanie Terezakis, Lindsey Sloan, Lindsey Sloan

Subjects: “…glioblastoma…”
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Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma by Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda

“…Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor and a subpopulation of glioma stem-like cells (GSCs) is likely responsible for the invariable recurrence following maximum resection and chemoradiotherapy. …”
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Long-Term Survival and Improved Quality of Life following Multiple Repeat Gamma Knife Radiosurgeries for Recurrent Glioblastoma Multiforme: A Case Report and Review of the Literature by Erik W. Larson, Halloran E. Peterson, Robert K. Fairbanks, Wayne T. Lamoreaux, Alexander R. Mackay, Jason A. Call, John J. Demakas, Barton S. Cooke, Christopher M. Lee

“…The management of glioblastoma multiforme (GBM) is in most cases complex and must be specifically tailored to the needs of the patient with the goals of extended survival and improved quality of life. …”
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Long non-coding RNA LBX2-AS1 activates IL4R to promote glioblastoma metastasis and angiogenesis by binding to the transcription factor NFKB1 by Qiang Li, Yong Cheng

Subjects: “…glioblastoma…”
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Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation by Karina Costa da Silva, Irlã Santos Lima, Cleonice Creusa dos Santos, Carolina Kymie Vasques Nonaka, Bruno Solano de Freitas Souza, Jorge Mauricio David, Henning Ulrich, Ravena Pereira do Nascimento, Maria de Fátima Dias Costa, Balbino Lino dos Santos, Silvia Lima Costa

“…Glioblastomas (GBM) are malignant tumours with poor prognosis. …”
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Discovery of mutated oncodriver genes associated with glioblastoma originated from stem cells of subventricular zone through whole exome sequence profile analysis, and drug repurposing by Arnob Sarker, Burhan Uddin, Reaz Ahmmed, Sabkat Mahmud, Alvira Ajadee, Md. Al Amin Pappu, Md. Abdul Aziz, Md. Nurul Haque Mollah

Subjects: “…Glioblastoma (GBM)…”
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