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Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro
Published 2025-03-01“…It exhibited expression of germ cell markers, including glial cell-derived neurotrophic factor family receptor alpha-1 (gfrα1) a and b, pou5f3, nanog, and vasa, but no expression of somatic cell markers such as amh, wt1a, and wt1b. …”
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62
The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice
Published 2025-01-01“…Interestingly, microglia-specific ABCA7ko restored Aβ42 peptide levels and IBA1+ and GFAP+ and NLRP3-related gene expression to the original APPPS1 mouse levels. In primary glial cell cultures of APPPS1-hA7ko microglia and APPPS1 astrocytes from newborn pups, we observed that conditioned media from LPS-stimulated microglia was able to induce NLRP3 inflammasome expression and proinflammatory cytokine release in astrocytes. …”
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63
Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome
Published 2025-02-01“…Gonadotropin-releasing hormone (GnRH) neurons are pivotal in regulating hypothalamic endocrine function, whereas tanycyte, a specialized glial cell type, potentially contribute to this process. …”
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64
Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes
Published 2025-02-01“…In contrast, type 2 closures exhibited sparse cone distribution and a prevalence of large, high-density cells, possibly indicating glial cell proliferation and exposed retinal pigment epithelium (RPE). …”
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65
Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…Recent studies indicated that TRPM2 regulates synaptic plasticity as well as the activation of glial cells. TRPM2 also modulates oxidative stress and inflammation through interaction with glial cells. …”
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66
Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
Published 2010-01-01“…Understanding the pattern of TLR signaling in the glial cells may lead to the identification of new targets for therapeutic application.…”
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67
Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation
Published 2013-01-01“…In the central nervous system (CNS), mastocytes and glial cells (microglia, astrocytes and oligodendrocytes) function as sensors of neuroinflammatory conditions, responding to stress triggers or becoming sensitized to subsequent proinflammatory challenges. …”
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68
A comparative study oıı the histomorphology of olfactory bulb in greyhound and outdoor dog
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69
Multiomics identify the gene expression signature of the spinal cord during aging process
Published 2025-02-01“…Flow cytometry reveals increased accumulation of free Fe2+ and ROS in senescent mixed glial cells; however, CCK-8 assays reveal that these cells are resistant to ferroptosis. …”
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70
Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice
Published 2010-01-01“…Thus, the transgenic mice show a profound pathology in glial cells of the spinal cord.…”
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71
Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes
Published 2020-01-01“…The plasticity of neurons and glial cells plays a vital role in the transmission and integration of signals in the central nervous system. …”
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72
Impact of the Ketogenic Diet on Neurological Diseases: A Review
Published 2025-01-01“…Thus, the KD represents a broad and promising strategy that involves both neurons and glial cells, with a molecular impact on brain metabolism and neuroinflammatory homeostasis. …”
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73
Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation
Published 2025-01-01“…We demonstrated that pEVs traverse the BBB by transcytosis and subsequently diffuse progressively into the brain. pEVs were then internalized by neuronal and radial glial cells as seen in Tg(huc:EGFP) and Tg(gfap:EGFP) zebrafish, respectively. …”
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74
Control of Chaotic Calcium Oscillations in Biological Cells
Published 2021-01-01“…The contribution of this present paper is to propose a method that combines a chemical Brusselator reaction-diffusion system with a biological cell system via gap junction for controlling and visualizing the frequency and magnitude of chaotic intracellular calcium oscillations in two cell types, including nonexcitable cells and the glial cells. This produces a wide variety of oscillatory behaviors similar to those reported in numerous biological experiments. …”
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75
Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma
Published 2021-01-01“…The present review focuses on how mitochondrial dysfunction may overwhelm the ability of neurons and glial cells to adequately maintain homeostasis and how mitochondria-derived DAMPs trigger the immune system and induce neurodegeneration.…”
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76
Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies
Published 2012-01-01“…Neuroinflammation in Parkinson's disease (PD) is a chronic process that is associated with alteration of glial cells, including astrocytes and microglia. However, the precise mechanisms remain obscure. …”
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77
Biomarkers and Their Possible Functions in the Intestinal Microenvironment of Chagasic Megacolon: An Overview of the (Neuro)inflammatory Process
Published 2021-01-01“…Components such as neuronal subpopulations, enteric glial cells, mast cells and their proteases, and homeostasis-related proteins from several organic systems (serotonin and galectins) are differentially involved in the progression of Chagasic megacolon. …”
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78
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials
Published 2018-01-01“…Gliomas are primary brain tumors presumably derived from glial cells. The WHO grade IV glioblastoma (GBM), characterized by rapid cell proliferation, easily recrudescent, high morbidity, and mortality, is the most common, devastating, and lethal gliomas. …”
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79
The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation
Published 2019-01-01“…Mitochondrial DAMPs have been shown to initiate proinflammatory immune responses from nonneuronal glial cells, including microglia and astrocytes; thereby, they have the potential to contribute to the chronic neuroinflammation present in these disorders accelerating the degeneration of neurons. …”
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80
Intestinal microbiome as effective regulator of enteral and central nervous system activity
Published 2018-08-01“…These data presumes the presence of direct microbiota-induced responses of enteric nervous system as well as its development and intestinal glial cells hemostasis maintenance. No evidence of direct involvement of these neurotransmitters in regulation of proximal enteral neurons synaptic activity is obtained. …”
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