Primary Spinal Germ Cell Tumors: A Case Analysis and Review of Treatment Paradigms by Joshua J. Loya, Henry Jung, Caroline Temmins, Nam Cho, Harminder Singh

“…Primary intramedullary spinal germ cell tumors are exceedingly rare. As such, there are no established treatment paradigms. …”
Get full text

Influence of Exposure to Benzo[a]pyrene on Mice Testicular Germ Cells during Spermatogenesis by Hueiwang Anna Jeng, Silvina M. Bocca

“…B[a]P exposure at ≤10 mg/kg/day for 30 days did not significantly alter concentrations of germ cells and mature spermatozoa and apoptotic response in germ cells and mature spermatozoa. …”
Get full text

Comparison of the MicroRNA Expression Profiles of Male and Female Avian Primordial Germ Cell Lines by Bence Lázár, Mahek Anand, Roland Tóth, Eszter Patakiné Várkonyi, Krisztina Liptói, Elen Gócza

“…Primordial germ cells (PGCs) are the precursors of adult germ cells, and among the embryonic stem-like cells in the bird embryo, only they can transmit the genetic information to the next generation. …”
Get full text

Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult by Toshihide Takahashi, Eiichi Ishikawa, Yosuke Masuda, Tetsuya Yamamoto, Taiki Sato, Makoto Shibuya, Akira Matsumura

“…Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. …”
Get full text

Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies by Emma Kearney, David Greenald, Gabriele Matilionyte, Sheila Lane, Melissa D Tharmalingam, Jill Davies, Jan-Bernd Stukenborg, Grace Forsyth, Rod T Mitchell

Subjects: Get full text

Seahorse nanos3 plays essential roles in germ cell development in the absence of nanos2 by Lingzhen Chen, Lu Tang, Qiang Lin, Yanhong Zhang

Subjects: Get full text

Chromatin environment-dependent effects of DOT1L on gene expression in male germ cells by Manon Coulée, Alberto de la Iglesia, Mélina Blanco, Clara Gobé, Clémentine Lapoujade, Côme Ialy-Radio, Lucia Alvarez-Gonzalez, Guillaume Meurice, Aurora Ruiz-Herrera, Pierre Fouchet, Julie Cocquet, Laïla El Khattabi

“…Taken together, our results show that H3K79me2 positively correlates with male germ cell genetic program throughout spermatogenesis, with DOT1L predominantly inhibiting rather than activating gene expression. …”
Get full text

Radical Resection of a Late-Relapsed Testicular Germ Cell Tumour: Hepatectomy, Cavotomy, and Thrombectomy by C. Ní Leidhin, C. E. Redmond, A. M. Cahalane, H. M. Heneghan, R. Motyer, E. R. Ryan, E. Hoti

“…Up to 3.2% of patients with testicular germ cell tumours represent with late-relapsing disease. …”
Get full text

Novel Genomic Aberrations in Testicular Germ Cell Tumors by Array-CGH, and Associated Gene Expression Changes by Rolf I. Skotheim, Reija Autio, Guro E. Lind, Sigrid M. Kraggerud, Peter W. Andrews, Outi Monni, Olli Kallioniemi, Ragnhild A. Lothe

“…Introduction: Testicular germ cell tumors of adolescent and young adult men (TGCTs) generally have near triploid and complex karyotypes. …”
Get full text

Clinicopathological spectrum of central nervous system germ cell tumors: A single-institution retrospective study by Sreelekha Appasani, Neelima Radhakrishnan, Anitha Mathews

Subjects: Get full text

The clinical significance of T cell infiltration and immune checkpoint expression in central nervous system germ cell tumors by Jiajun Zhou, Jiajun Zhou, Wenhao An, Lei Guan, Lei Guan, Jinyu Shi, Qiaozhen Qin, Shuai Zhong, Zheng Huang, Rui Liu, Chenxing Wu, Zhong Ma, Xueling Qi, Xiaoxia Jiang, Yan Wang, Shouwei Li

Subjects: “…germ cell tumor…”
Get full text

Mixed Germ Cell Tumor of Testis with Isolated Scapular Metastasis: A Case Report and Review of the Literature by Dipti Rani Samanta, Chaitali Bose, Roopesh Krishnappa, Saumyaranjan Mishra, Sulagna Mohanty, Ashish Upadhyay, Surendra Nath Senapati

“…Bone metastasis is a rare entity in germ cell tumor of testis and is a poor prognostic site. …”
Get full text

Primary orbital yolk sac tumor in an infant: A rare entity by Varsha Mishra, Sandeep Jain, Payal Malhotra, Garima Durga, Gauri Kapoor

Subjects: “…germ cell tumor…”
Get full text

Subculture of Germ Cell-Derived Colonies with GATA4-Positive Feeder Cells from Neonatal Pig Testes by Kyung Hoon Lee, Won Young Lee, Jin Hoi Kim, Chan Kyu Park, Jeong Tae Do, Jae Hwan Kim, Young Suk Choi, Nam Hyung Kim, Hyuk Song

“…Enrichment of spermatogonial stem cells is important for studying their self-renewal and differentiation. Although germ cell-derived colonies (GDCs) have been successfully cultured from neonatal pig testicular cells under 31°C conditions, the short period of in vitro maintenance (<2 months) limited their application to further investigations. …”
Get full text

Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours by Gazanfer Belge, Markus Klemke, Bendix Hansen, Cansu Dumlupinar, Aylin Igde, Dirk Arnold, Hans Salwender, Christian Wülfing, Armin Soave, Klaus-Peter Dieckmann

Subjects: “…Testicular germ cell tumour…”
Get full text

A face-off between Smaug and Caspar modulates primordial germ cell count and identity in Drosophila embryos by Girish Deshpande, Subhradip Das, Adheena Elsa Roy, Girish S Ratnaparkhi

“…Proper formation and specification of Primordial Germ Cells (PGCs) is of special significance as they gradually transform into Germline Stem Cells (GSCs) that are ultimately responsible for generating the gametes. …”
Get full text

Case Report: A crushing sensation—a rare case of mediastinal germ cell tumor causing cardiac tamponade by Kevin S. Tang, Emin Zargarian, Pranav M. Patel

Subjects: Get full text

Down syndrome with cryptorchidism and retroperitoneal mixed germ cell tumour in an adult patient: a case report and literature review by Qiang Wang, Hai-bin Zhou, Li Ao, Yi Jiang, Xiao-Cong Zhou

Subjects: Get full text

Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“… BackgroundPrimary intracranial germ cell tumors (iGCTs) are highly malignant brain tumors that predominantly occur in children and adolescents, with an incidence rate ranking third among primary brain tumors in East Asia (8%-15%). …”
Get full text

Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding by Srinath Sundararajan, Beth Braunhut, Frederick Ahmann, Amit Agarwal

“…Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. …”
Get full text