Low-exhaustion peripheral circulating γδ T cells serve as a biomarker for predicting the clinical benefit rate of non-small cell lung cancer (NSCLC) patients to chemotherapy or tar... by Dongdong Zhang, Guichao Liu, Jinhui Ye, Ke Li, Guojun Zhang, Qiang Quan, Xinhai Zhu, Peng Li

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New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Stu... by Liang J, Tang B, Shen J, Rejiepu M, Guo Y, Wang X, Shao S, Guo F, Wang Q, Zhang L

“…Junqing Liang,1,2 Baopeng Tang,1,2 Jun Shen,1,2 Manzeremu Rejiepu,1,2 Yankai Guo,1,2 Xiaoyan Wang,1,2 Shijie Shao,1,2 Fei Guo,3 Qin Wang,4 Ling Zhang1 1Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Cardiac Pacing and Electrophysiology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 3Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People’s Republic of China; 4Department of Geriatrics and Cadre Ward, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Qin Wang; Ling Zhang, Email w2036661q@126.com; ydzhangling@126.comBackground: The common occurrence of atrial fibrillation (AF) as a cardiac arrhythmia, along with its link to sleep deprivation (SD), is gaining more acknowledgment. …”
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A phenotype-based AI pipeline outperforms human experts in differentially diagnosing rare diseases using EHRs by Xiaohao Mao, Yu Huang, Ye Jin, Lun Wang, Xuanzhong Chen, Honghong Liu, Xinglin Yang, Haopeng Xu, Xiaodong Luan, Ying Xiao, Siqin Feng, Jiahao Zhu, Xuegong Zhang, Rui Jiang, Shuyang Zhang, Ting Chen

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Cognitive Decline in Chronic Migraine with Nonsteroid Anti-inflammation Drug Overuse: A Cross-Sectional Study by Xiaoying Cai, Xiaotian Xu, Aiwu Zhang, Jianwen Lin, Xiaojuan Wang, Wen He, Yannan Fang

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Influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and establishment of nomogram model by Ganlin Wu, Ganlin Wu, Yanli Ye, Meirong Xu, Yanxia Zhang, Zuopeng Lu, Lv Huang

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Perceptions of ethical decision-making climate among clinicians working in European and US ICUs: differences between religious and non-religious healthcare professionals by Hanne Irene Jensen, Hans-Henrik Bülow, Lucas Dierickx, Stijn Vansteelandt, Rosanna Vaschetto, Gábor Élö, Ruth Piers, Dominique D. Benoit

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Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

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Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage? by Yunfei Song, Guoqiang Song, Guijing Liu, Limei Mao, Xiuhu An, Chao Peng, Jian Li, Yan Chen, Hongwen Li, Changkai Hou, Bangyue Wang, Yan Zhao, Xiangdong Wang, Gangfeng Yin, Xinyu Yang

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Global disparities in cancer supportive care: An international survey by Alexandre Chan, Lawson Eng, Changchuan Jiang, Mary Dagsi, Yu Ke, Mary Tanay, Cristiane Bergerot, Niharika Dixit, Ana Cardeña Gutiérrez, Ana I. Velazquez, Farhad Islami, Enrique Soto‐Perez‐de‐Celis

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Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIEL... by Ralf E Harskamp, Karen Pieper, A John Camm, Ajay K Kakkar, Jelle C L Himmelreich, Saverio Virdone, Jean-Pierre Bassand, Frank Misselwitz, Freek W A Verheugt, Frank Cools, Harry Gibbs, Antônio C Pereira-Barretto

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Immune checkpoint inhibitor-induced diabetes mellitus: clinical characteristics and risk factors by Mei Zhan, Mei Zhan, Qinran Long, Qinran Long, Jinhan He, Jinhan He, Jinhan He, Litao Huang, Bin Wu, Bin Wu, Haixia Xu, Li Mo, Ting Xu

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Development and validation of a novel artificial intelligence algorithm for precise prediction the postoperative prognosis of esophageal squamous cell carcinoma by Zichen Wang, Zhihan Xiao, Tongyu Zhang, Meiyou Lu, Hai Li, Jing Cao, Jianan Zheng, Yichan Zhou, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu

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Multiomics identify the gene expression signature of the spinal cord during aging process by Lintao Xu, Jingyu Wang, Jinjie Zhong, Weiwei Lin, Gerong Shen, Ning He, Xingjia Mao, Chunyan Fu, Zhaobo Huang, Fengdong Zhao, Xin Ye, Yongjian Zhu, Mingzhi Zheng, Hui Li, Lin-lin Wang, Kai Zhong, Lijun Zhu, Ying-ying Chen

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T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates by Joanna M. Schaenman, MD, PhD, Harry Pickering, PhD, Elaine F. Reed, PhD, Maura Rossetti, PhD, Benjamin Seligman, MD, S. Samuel Weigt, MD, Michael Shino, MD, David Sayah, MD, PhD, John Belperio, MD, Ashley Hu, MD, Ashley Prosper, MD, Kathleen Ruchalski, MD, Abbas Ardehali, MD, Reshma Biniwale, MD

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Global research landscape and hotspots for ferroptosis in glioma: A comprehensive bibliometric and visual analysis by Xinyue Zheng, Mengyao Diao, Shan Tong, Shuo Yang, Jing Lin, Shenghua Zhuo, Ting Wang, Jian Dai, Shenbo Chen, Kai Wang

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Clinicopathological and predictive value of MAIT cells in non-small cell lung cancer for immunotherapy by Dongyan Shi, Lin Lin, Yun Chen, Jian Liu, Lin Shi, Jinying Lu, Da Zhong, Meijuan Song, Wenhua You, Wen-Hui Li

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Association between adult body shape index and serum levels of the anti-aging protein Klotho in adults: a population-based cross-sectional study of the NHANES from 2007 to 2016 by Li Gong, Jinghan Xu, Yiyang Zhuang, Liwei Zeng, Zhenfei Peng, Yuzhou Liu, Yinluan Huang, Yutian Chen, Fengyi Huang, Chunli Piao

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Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

“…Hang Yin,1– 5,* Xiaoxing Li,6,* Dazhou Lu,1– 5,* Xin Zhao,7,* Zeyu Yang,1– 5 Zerui Wang,1– 5 Feng Xu,1– 5 Yuguo Chen,1– 5 Chuanbao Li1– 5 1Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 2Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Chest Pain Center, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 3Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province, Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 4Shandong Key Laboratory: Magnetic Field-Free Medicine & Functional Imaging (MF), Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 5NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 6Department of Geriatrics, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 7Department of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanbao Li; Yuguo Chen, Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China, Email bao2460@126.com; chen919085@sdu.edu.cnBackground: Aortic dissection (AD) is a life-threatening cardiovascular emergency and currently lacks effective drug treatment. …”
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CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

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Pre-immunotherapy alters stereotactic ablative radiotherapy-induced systemic T cell responses in early-stage NSCLC by Chao Liu, Yanjuan Chen, Xiaohui Li, Zhijie Bai, Meilin Jiang, Dongsheng Sheng, Wenxue Zou, Rui Huang, Qingyu Huang, Fuhao Wang, Jingyang Zhu, Huiru Sun, Bing Liu, Zongcheng Li, Bing Sun

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