Suggested Topics within your search.
Suggested Topics within your search.
- Biochemistry 3
- Genetics 3
- Genetic Phenomena 2
- Genetic Techniques 2
- Molecular biology 2
- Biochemical Phenomena 1
- Clinical biochemistry 1
- Diagnostic Techniques and procedure 1
- Droit 1
- Genanalyse 1
- Genetic Structures 1
- Genetik 1
- Genome stability 1
- Genomics 1
- Germ cells-development 1
- Immunohistochemistry 1
- Medical laws and legislation 1
- Methodology 1
- Microbiology 1
- Molecular Biology 1
- Molecular genetics 1
- Médecine 1
- Research 1
- biology 1
- gene control 1
- neoplasm-diagnosis 1
-
4621
Identification of Differentially Expressed Genes and Signaling Pathways in Acute Myocardial Infarction Based on Integrated Bioinformatics Analysis
Published 2019-01-01“…These DEGs were performed through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses by using Clusterprofiler package. …”
Get full text
Article -
4622
Resistance to viruses of potato: current status and prospects
Published 2017-03-01“…Recently developed new genome editing technologies with the potential to be a powerful tool for gene design open up broad opportunities for development of next-generation resistance genes. …”
Get full text
Article -
4623
Transcriptomic Response of Arabidopsis thaliana to Pseudomonas syringae Infection: An In Silico Approach
Published 2024-09-01“…A total number of 22 biological pathways were significantly enriched with up-/down-regulated differentially expressed genes (DEGs) in the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Also, 39 TFs of A. thaliana were altered during the bacterial infection. …”
Get full text
Article -
4624
Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration
Published 2025-02-01“…ObjectiveTo build a new prognostic risk assessment model based on immune cell co-expression networks for predicting overall survival and evaluating the efficacy of immunotherapy for colon cancer patients.MethodsThe Cancer Genome Atlas (TCGA) database was used to obtain mRNA expression profiling data, clinical information, and somatic mutation data from colorectal cancer patients. …”
Get full text
Article -
4625
Genotyping-by-sequencing derived SNP markers reveal genetic diversity and population structure of Dactylis glomerata germplasm
Published 2025-02-01“…The majority of the genetic variation (85.8%) was observed within clusters, with minimal differentiation among clusters (FST = 0.007). Genome-wide association studies (GWAS) identified significant marker-trait associations for dry biomass weight, a critical agronomic trait, with markers DArT-100715788, DArT-101043591, and DArT-101171265 and DArT-101090822 located on Chromosomes 1, 6, and 7 respectively. …”
Get full text
Article -
4626
High-Resolution Melting Analysis to Detect Antimicrobial Resistance Determinants in South African Neisseria gonorrhoeae Clinical Isolates and Specimens
Published 2022-01-01“…Real-time PCR and high-resolution melting analysis were used to detect porA pseudogene (species-specific marker) and resistance-associated targets. Whole-genome sequencing was used as the gold standard for the presence of point mutations. …”
Get full text
Article -
4627
Taxonomic refinement of Bacillus thuringiensis
Published 2025-02-01“…By October 2023, whole genome sequences (WGS) of 885 bacterial strains were labeled as B. thuringiensis in the NCBI GenBank database. …”
Get full text
Article -
4628
Ganciclovir Resistance-Linked Mutations in the HCMV <i>UL97</i> Gene: Sanger Sequencing Analysis in Samples from Transplant Recipients at a Tertiary Hospital in Southern Brazil
Published 2025-01-01“…<b>Background/Objectives:</b> Human cytomegalovirus (HCMV) DNAemia remains a significant concern for transplant recipients, largely due to mutations in the viral genome that may lead to antiviral-resistant strains. …”
Get full text
Article -
4629
Cooperation Between <i>Rhodococcus qinshengii</i> and <i>Rhodococcus erythropolis</i> for Carbendazim Degradation
Published 2024-12-01“…Sequencing analysis of genomes of both strains revealed the presence of <i>cbm</i>A, the gene coding for the enzyme that hydrolyses carbendazim to produce 2-aminobenzimidazole (2-AB). …”
Get full text
Article -
4630
Different DNA Loidy Patterns for the Differentiation of Common Subtypes of Renal Tumors
Published 2005-01-01“…DNA ploidy is viewed as a marker of gross genomic aberrations. The aim of this study is to evaluate the DNA ploidy in the common subtypes of renal tumors to increase our understanding of renal tumor biology and to broaden clinical application of DNA ploidy. …”
Get full text
Article -
4631
Analysis of Bacterial Diversity in Different Heavy Oil Wells of a Reservoir in South Oman with Alkaline pH
Published 2018-01-01“…Molecular approaches like proteomic and genomic characterization of the isolates are replacing the traditional method of identification with systemic classification. …”
Get full text
Article -
4632
Enhanced membrane protein production in HEK293T cells via ATF4 gene knockout: A CRISPR-Cas9 mediated approach
Published 2025-01-01“…Comparative evaluations were conducted using all-in-one and two-vector systems. Genome sequencing and membrane protein productivity of ATF4-KO cells were compared to wild-type cells using next-generation sequencing (NGS) and a membrane protein isolation kit, respectively. …”
Get full text
Article -
4633
Drought Adaptation and Responses of Stipa krylovii Vary Among Different Regions: Evidence From Growth, Physiology, and RNA‐Seq Transcriptome Analysis
Published 2025-01-01“…By Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis on gene expressions of individuals from each treatment, unique enriched pathways were found under heavy drought. (2) The decrease in the number of tillers with the increasing drought was much lower for individuals from the western region than those from the other two regions. …”
Get full text
Article -
4634
Causal association among smoking, bitter beverage consumption, and risk of osteoporosis: a two-sample mendelian randomization-based study
Published 2025-01-01“…Methods Publicly available genome-wide association study summary data were analyzed using MR methods. …”
Get full text
Article -
4635
Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model
Published 2020-05-01“…Throughout evolution, anthropogenic Variola virus (VARV) has developed effective mechanisms to overcome human defense reactions. The viral genome encodes soluble proteins imitating the structure of cellular cytokine receptors. …”
Get full text
Article -
4636
Transcriptomic reprogramming and epigenetic regulation underlying pollination-dependent and auxin-induced fruit set in tomato
Published 2025-02-01“…Notably, this developmental process can also proceed in the absence of flower fertilization, although it remains unclear whether pollination-dependent and pollination-independent fruit sets undergo similar transcriptomic reprogramming. Genome-wide transcriptomic profiling of the flower-to-fruit transition, either pollination-induced or triggered by auxin treatment, shows that both types of triggers modulate the expression of a common large set of genes primarily expressed in maternal tissues. …”
Get full text
Article -
4637
Comparative analysis of the DNA isolated from thyme leaves using different methods
Published 2020-10-01“…Among the tested kits and methods, CTAB + 2% PVP provided thyme DNA suitable for PCR and, presumably, for genome library preparation. The low cost of reagents for this technique makes it applicable for future mass analysis of plant material.…”
Get full text
Article -
4638
Combination of inflammatory proteins in serum can be used to diagnose papillary thyroid carcinoma with lymph node metastasis
Published 2025-01-01“…Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Gene Set Enrichment Analysis were used to analyze the potential regulatory pathways. …”
Get full text
Article -
4639
mRNA technology as one of the promising platforms for the SARS-CoV-2 vaccine development
Published 2020-12-01“…After the genome sequence of SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus 2) was published and the number of infected people began to increase rapidly, many global companies began to develop a vaccine. …”
Get full text
Article -
4640
Newly identified single-nucleotide polymorphism associated with the transition from nonalcoholic fatty liver disease to liver fibrosis: results from a nested case-control study in...
Published 2025-12-01“…To quantify gene expression, we used real-time PCR with fluorescence detection.Results The study analyzed data from 5467 participants (1094 cases and 4373 controls). Genome-wide association analysis identified nine significant loci, including the novel rs2073080 variant, strongly associated with NAFLD-associated hepatic fibrosis. …”
Get full text
Article