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4541
Use of Magnetic Nanoparticles as Targeted Therapy: Theranostic Approach to Treat and Diagnose Cancer
Published 2017-01-01Get full text
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4542
Analysis of polymorphism at the <i>FaRca1</i> locus to identify strawberry genotypes resistant to <i>Colletotrichum acutatum</i>
Published 2025-01-01“…Promising genetic sources for marker-assisted breeding are strawberry cultivars combining several resistance factors in the genome: ‘Borovitskaya’ and ‘Aprica’ (FaRca1 and Rca2 anthracnose resistance loci), ‘Korona’ and ‘Ostara’ (FaRca1 anthracnose resistance locus, and 08 To-f powdery mildew resistance locus), and ‘Bylinnaya’ (FaRca1 anthracnose resistance locus, 08 To-f powdery mildew resistance locus, and Rpf1 red stele root rot resistance locus).…”
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4543
Physiological Alterations due to Hepatotoxicity and the Protective Role of Cleome viscosa Linn Seed Extract in Experimental Animals
Published 2022-01-01“…DNA damage protection potential of the crude seed extract was carried out using extract of the genomic DNA nicking assay. Hepatoprotective activity of the crude seed extract of the plant was carried out based on CCl4-induced liver damage in Wister albino rats. …”
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4544
Effect of Mitochondrial Tu Translation Elongation Factor on Water-holding Capacity of Qinchuan Cattle Meat during Postmortem Aging
Published 2025-01-01“…Through proteomics, 23 differential proteins related to TUFM were identified, and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that the differential proteins could mediate cellular autophagy by participating in energy metabolism through a variety of pathways. …”
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4545
Association of LPCAT1-rs8352 genetic variant with susceptibility and severity of pediatric bronchial asthma: a case-control study
Published 2025-01-01“…Neonatal blood DNA was extracted using the Gene JET™ Whole Blood Genomic DNA Purification Mini Kit. Genotyping was performed by RT-PCR. …”
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4546
Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer
Published 2024-09-01“…Methods The multi-omics features of disulfidptosis genes in gastric cancer were first analyzed based on The Cancer Genome Atlas(TCGA) database. DRLncs were further screened, and disulfidptosis related gene recurrence score (DRG-RS) model was constructed to predict the overall survival(OS) and correlation with the clinical characteristics of gastric cancer patients. …”
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4547
Toll-like receptor 4 pathway evolutionary trajectory and functional emergence
Published 2025-01-01“…Our previous work on pan-genome-wide survey, indicates Callorhincus milli to be the ancestral organism with both TRAM and TRIF proteins.MethodsTo gain a deeper insight into the protein function and to compare them with Homo sapiens adaptor proteins, we modeled the docking of the TRAM–TRIF complex of representative organisms across various taxa. …”
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4548
Liver Microbiome in Healthy Rats: The Hidden Inhabitants of Hepatocytes
Published 2023-01-01“…The main function composition of the genomes of annotated bacteria was correlated with metabolism (79.92±0.24%). …”
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4549
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4550
Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling
Published 2024-01-01“…However, there is no information associating primary damage to the astrocyte genome, the DNA damage response (DDR), and the EV and NT repertoire. …”
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4551
Intraspecific diversity of durum wheat (Triticum durum Desf.): a unif ied classif ication
Published 2021-06-01“…., which is based on the genomic composition of species and the presence or absence of a number of main genes that govern the “classification” traits. …”
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4552
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4553
Molecular genetic characteristics of broccoli (Brassica oleracea L. var. italica Plenck) from the VIR collection
Published 2020-10-01“…For the analysis, 35 markers of microsatellite sequences specific to the Brassica L. genome were selected. PCR products were separated by electrophoresis on a 3% agarose gel.Results and conclusions. …”
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4554
Exploring the influences of education, intelligence and income on mental disorders
Published 2024-02-01“…However, the direct effects of each factor on major mental disorders are unclear.Aims We aimed to evaluate the overall and independent causal effects of the three psychosocial factors on common mental disorders.Methods Using genome-wide association study summary datasets, we performed Mendelian randomisation (MR) and multivariable MR (MVMR) analyses to assess potential associations between the 3 factors (EA, N=766 345; household income, N=392 422; intelligence, N=146 808) and 13 common mental disorders, with sample sizes ranging from 9907 to 807 553. …”
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4555
Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius.
Published 2025-02-01“…To this end, an infectious bacterial artificial chromosome (BAC) harboring the complete genome of the MDV-1 very virulent strain Md5 was generated, and the rescued rMd5 maintained biological properties similar to the parental virus both in vitro and in vivo. …”
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4556
Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases
Published 2022-01-01“…Methods. miRNA and mRNA sequencing data for 80 UM patients were obtained from The Cancer Genome Atlas (TCGA) database. The patients were further randomly assigned to a training set (n = 40, used to identify key miRNAs) and a testing set (n = 40, used to internally verify the signature). …”
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4557
Activation of endogenous tolerance to bleaching stress by high salinity in cloned endosymbiotic dinoflagellates from corals
Published 2025-01-01“…The findings also suggest the genomes of coral symbiotic dinoflagellates have undergone evolutionary processes to develop mechanisms, regulated by gene expression, to mitigate damages caused by high temperature and high light stress. …”
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4558
Diversity of reverse-transcriptase-containing viruses through global metagenomics
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4559
High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
Published 2022-01-01“…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that UPK3A was involved in the p53 signaling pathway. …”
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4560
Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer
Published 2025-02-01“…Transcriptome and clinical data of patients with GC were collected from The Cancer Genome Atlas and Gene Expression Omnibus datasets. …”
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