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4521
Azurin a potent anticancer and antimicrobial agent isolated from a novel Pseudomonas aeruginosa strain
Published 2025-01-01“…The presence of the azurin gene was confirmed in the genomic DNA using specific oligonucleotide primers, and azurin expression was also detected in the synthesized cDNA, which revealed that the azurin expression is active. …”
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4522
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4523
The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis
Published 2025-01-01“…The purpose of this study was to use Mendelian randomization (MR) analysis to investigate the causal relationship between smoking phenotypes and OA risk from a genetically informed standpoint.MethodsAs instrumental variables (IVs) based on single nucleotide polymorphisms (SNPs), this study used the summary-level data of corresponding genome-wide association study (GWAS) for five smoking phenotypes involving 1,694,781 samples. …”
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4524
Estimating the Genetic Diversity of Oranges Citrus spp. in South Sulawesi, Indonesia, Using RAPD Markers
Published 2023-01-01“…Leaf samples of 13 orange varieties were collected from the five production centers: Pangkep, Sidrap, Bantaeng, North Luwu, and Selayar in South Sulawesi, Indonesia. Genomic DNA extraction from the orange leaves followed the protocol of the DNA Mini Kit Geneaid. …”
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4525
Polymorphism of RAPD and ISSR markers in grain amaranth species
Published 2017-04-01“…Due to the lack of research and depending on the environmental conditions, the morphological markers of amaranth are not able to provide sufficient genomic information to the breeder; thus it is necessary to search for reliable genetic markers that allow the genetic diversity of the Amaranthus L. species to be studied and effectively maintained. …”
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4526
Paternal metabolic and cardiovascular programming of their offspring: A systematic scoping review.
Published 2020-01-01“…<h4>Background</h4>There is lots of evidence that maternal peri-gestational metabolic, genomic and environmental conditions are closely linked to metabolic and cardiovascular outcomes in their offspring later in life. …”
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4527
Development of a Novel Prognostic Model for Lung Adenocarcinoma Utilizing Pyroptosis-Associated LncRNAs
Published 2025-01-01“…This study used genotype-tissue expression (GTEx) and the cancer genome atlas (TCGA) databases to obtain 477 lung adenocarcinoma (LUAD) and 347 healthy individuals’ samples as research subjects and divided LUAD patients into low-risk and high-risk groups based on prognostic risk scores. …”
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4528
Functional properties of the Su(Hw) complex are determined by its regulatory environment and multiple interactions on the Su(Hw) protein platform
Published 2019-03-01“…Some insulator complexes contribute to the higher-order organization of chromatin in topologically associated domains that are fundamental elements of the eukaryotic genomic structure. The Su(Hw)-dependent protein complex is a unique model for studying the insulator, since its basic structural components affecting its activity are already known. …”
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4529
The use of wheatgrass (<i>Thinopyrum intermedium</i>) in breeding
Published 2022-09-01“…The first consensus map of wheatgrass containing 10,029 markers was obtained, which is important for searching for genes and their introgressions to the wheat genome. The results of research on the nutritional and technological properties of wheatgrass grain for the development of food products as well as the differences in the quality of wheatgrass grain and wheat grain are presented.…”
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4530
Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study.
Published 2025-01-01“…In addition, the core genes were analyzed using gene set enrichment analysis and single-gene genome variation analysis.<h4>Results</h4>Analysis of DEGs on gene chips from OA and AD patients revealed significant changes in gene expression patterns. …”
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4531
Antioxidant Properties of Popular Turmeric (Curcuma longa) Varieties from Bangladesh
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4532
Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study
Published 2025-02-01“…We aimed to investigate the bidirectional causal relationships between frailty measures and sleep disturbances employing a two-sample Mendelian randomization (MR) analysis.Methods: Two-sample MR analyses were performed based on large-scale genome-wide association studies (GWAS) of the European population for frailty index (FI) (N = 175,226), Fried Frailty Score (FFS) (N = 386,565), insomnia (N = 283,595), sleep duration (N = 445,966) and sleep apnea (N = 523,366). …”
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4533
Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…After Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and circRNA–miRNA network analyses, circDOCK1 was chosen for further investigation. …”
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4534
The problem of norovirus infection in animals (literature review)
Published 2024-06-01“…The noroviruses were detected in fecal samples from humans, cattle, pigs, sheep, dogs, cats, mice, as well as in pork and milk samples. The norovirus genome is prone to mutations, resulting in antigenic shifts and recombination, as well as the emergence and rapid spread of new epidemic and epizootic variants. …”
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4535
Diversification and recurrent adaptation of the synaptonemal complex in Drosophila.
Published 2025-01-01“…Overall, our study recapitulates the poor conservation of SC components, and further uncovers that the lack of conservation extends to other modalities including copy number, genomic locale, and germline regulation. Considering the elevated testes expression in many Drosophila species and the common ancestor, we suggest that the activity of SC genes in the male germline, while still poorly understood, may be a prime target of constant evolutionary pressures driving repeated adaptations and innovations.…”
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4536
MAIP1-Related Tumor Immune Infiltration: As a Potential Prognostic Biomarker for Esophageal Cancer
Published 2022-01-01“…We obtained RNA-seq datasets and corresponding clinical data for EC patients from the Cancer Genome Atlas (TCGA) database via the UCSC Xena browser to extract MAIP1 expression and plot survival curves to determine their prognosis. …”
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4537
Atypical Femoral Fracture in Hypophosphatasia: A Systematic Review
Published 2023-01-01Get full text
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4538
Molecular Detection and Phylogenetic Analysis of the alkB Gene in Klebsiella oxytoca Strains Isolated from the Gut of Tenebrio molitor
Published 2024-01-01“…The alkB gene sequence identical to fourteen alkB gene sequences derived from Actinobacteria whole genome was detected in Klebsiella oxytoca for the first time to the best of our knowledge. …”
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4539
A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells
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4540