A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets by Xinghao Fu, Feihong Ji, Qi He, Xinguang Qiu

“…We first explored the potential carcinogenic effect of YY1 in 33 cancers using the cancer genome atlas (TCGA) project and gene expression omnibus (GEO) datasets in this research. …”
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التشخيص الجزيئي لنبات البوثس Epipremnum aureum المستزرع في محافظة نينوى لاول مرة في العراق by شهد ابراهيم, جهان الحاتم, انوار الطائي

“…تم في هذا البحث دراسة المؤشر الوراثي الجزيئي للنبات المدروس البوثس Epipremnum aureum باستعمال تقنية تفاعل التضاعفي المتخصص Specific - PCR اذ تم مكاثرة قطع الDNA باستعمال الكت الموصى به Favor PrepTM (Genomic DNA Extraction Mini Kit) وتضمينها من خلال تفاعل البلمرة المتسلسل Polymerase Chain Reaction واظهرت نتيجة الكشف عند المستوى الجزيئي لجينوم اوراق نبات البوثس أن حجوم الحزم الناتجة كان مطابقاً لما جاء في تصميم زوج البوادئ (ITS1F: 5:TCCGTAGGTGAACCTGCGG-3)) (ITS4R:5:TCCTCCGCTTATTGATAGC-3) المسؤول كمحدد عن وجود المورث قيد الدراسة وظهرت الحزم اثناء الترحيل الكهربائي بحجم 473 زوج قاعدة , أدخلت تسلسلات القواعد النتروجينية في برنامج NCBI-BLAST وبرنامج MEGA 6.0 لبيان مدى تقاربها مع المورثات الموجودة والمسجلة في بنك الجينات Gene Bank . …”
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Evolutionary analysis of DELLA proteins in sweet potato and related species reveals their roles in development and stress responses by Zhidan Zuo, Haoqiang Zhao, Yue Fan, Yixuan Zhu, Wenpeng Song, Hong Zhai, Shaozhen He, Huan Zhang, Ning Zhao, Qingchang Liu, Shaopei Gao

“…Despite the pivotal role of DELLA proteins, a comprehensive genome-wide analysis of the DELLA gene family in sweet potato (Ipomoea batatas) and its related species has yet to be conducted. …”
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Detection of multidrug resistant Vibrio parahaemolyticus and anti-Vibrio Streptomyces sp. MUM 178J by Ke-Yan Loo, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Priyia Pusparajah, Learn-Han Lee, Vengadesh Letchumanan

“…Further identification with genomic analyses confirmed that 64% (64/100) of the isolates were V. parahaemolyticus. …”
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Involvement of transposable elements in neurogenesis by R. N. Mustafin, E. K. Khusnutdinova

“…A possible mechanism for the implementation of this mechanism may be reverse transcription of mRNA and site-specific insertion into the genome with a regulatory effect on the genes involved in the memory.…”
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Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology by Jinke Huang, Yijun Zheng, Jinxin Ma, Jing Ma, Mengxiong Lu, Xiangxue Ma, Fengyun Wang, Xudong Tang

“…Based on the identified overlapping common targets, drug-ingredient-target gene network, Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and protein-protein interaction (PPI) analysis were conducted. …”
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From threats to solutions: A literature review of climate adaptation in anadromous salmon and trout by Lisa G. Crozier, Jared E. Siegel

“…By capitalizing on new tools for sequencing, genomic analysis, and automated field data collection, we can establish baselines for tracking evolutionary responses to climate change. …”
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Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways by Linjie Fang, Tingyu Tang, Mengqi Hu

“…Later, by the Database for Annotation, Visualization, and Integrated Discovery (DAVID), they were enriched in the Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. It was found that the upregulated DEGs were enriched in the type I interferon signaling pathway, AGE-RAGE signaling pathway in diabetic complications, coronavirus disease, etc. …”
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High-throughput sequence-based microsatellite genotyping for the non-model Neotropical tree species Anadenanthera colubrina (Leguminosae) by Alejandra Lorena Goncalves, María Victoria García, Emilie Chancerel, Olivier Lepais, Myriam Heuertz

“…Next-generation sequencing (NGS) strategies allow simple and cost-effective development of new SSR loci from low-coverage whole genome shotgun sequencing. The main aim was to develop microsatellite markers for sequence-based high-throughput genotyping (SSRseq) in the species and to characterize their information content against traditional capillary electrophoresis-based microsatellite data by estimating the amount of molecularly accessible size homoplasy of each locus. …”
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Emergence of a novel porcine pestivirus with potential for cross-species transmission in China, 2023 by Li-shuang Deng, Tong Xu, Zhi-wen Xu, Ling Zhu

“…Viremia has been detected in both piglets and mice, with high viral genome loads found in various organs. In vitro results revealed that PAAPeV replicates in ST cells and, to a lesser extent, in human (A549 and HepG2) and monkey (Vero) cells. …”
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Streptomyces sp. strain MUSC 5 from mangrove forest in Malaysia: Identification, antioxidant potential and chemical profiling of its methanolic extract by Hefa Mangzira Kemung, Loh Teng-Hern Tan, Kok-Gan Chan, Hooi-Leng Ser, Jodi Woan-Fei Law, Bey Hing Goh

“… The present study explored the antioxidant potential of a Streptomyces sp. strain MUSC 5 from the mangrove forest soil in the Pahang State, Peninsular of Malaysia and determined the presence of biologically active chemical constituents contained in the methanolic extract. The 16S rRNA genomic DNA extraction, phylogenetic analysis and phenotyping methods were used to confirm identity of strain. …”
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Computer analysis shows differences between mitochondrial miRNAs and other miRNAs by P. S. Vorozheykin, I. I. Titov

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Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model. by Emily Mantlo, Junki Maruyama, John T Manning, Rachel A Reyna, Cheng Huang, Slobodan Paessler

“…<h4>Methods</h4>We report the development of a reverse genetics system for the MACV lineage II Chicava strain, using a pRF42 plasmid encoding the L and S segment genomic RNA under the transcriptional control of a murine DNA-dependent RNA polymerase I promoter sequence. …”
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Investigating the role of iron status in the development of coeliac disease: a Mendelian randomisation study by Isabel A Hujoel, Margaux Louise Anna Hujoel

“…The SNPs were drawn from a meta-analysis of three genome-wide association studies (GWAS). The association between these SNPs and coeliac disease was assessed using GWAS summary statistics from the UK Biobank. …”
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Estimation of translational importance of mammalian mRNA nucleotide sequence characteristics based on ribosome profiling data by O. A. Volkova, Yu. V. Kondrakhin, R. N. Sharipov

“…Thanks to ribosome profiling technology, genome-wide experimental data of translation efficiency have been obtained for many eukaryotic mRNAs. …”
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Bioinformatics Method Was Used to Analyze the Highly Expressed Gene FAM83A of Breast Cancer in Young Women by Yongzhe Tang, Hao Wang, Qi He, Yuanyuan Chen, Jie Wang

“…Digital gene representation of the Tumor Genome Project Data Library was used to select differentially expressed genes in breast cancer tissue and breast benign tumor tissue. …”
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Multiomic machine learning on lactylation for molecular typing and prognosis of lung adenocarcinoma by Mengmeng Hua, Tao Li

“…LRG mRNA and long non-coding RNA transcriptomes, epigenetic methylation data, and somatic mutation data from The Cancer Genome Atlas LUAD cohort were analyzed to identify lactylation cancer subtypes (CSs) using 10 multiomics ensemble clustering techniques. …”
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Lessons from SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections: What We Know So Far by Radi Taha Alsafi

“…Therefore, this review summarizes the state-of-the-art information and compares the similarities and dissimilarities between SARS-CoV, MERS-CoV, and SARS-CoV-2, in terms of their evolution trait, genome organization, host cell entry mechanisms, tissue infectivity tropisms, transmission routes and contagiousness, and the clinical characteristics, laboratory features, and immunological abnormalities of their related illnesses. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

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The molecular view of mechanical stress of brain cells, local translation, and neurodegenerative diseases by T. M. Khlebodarova

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