Showing 4,061 - 4,080 results of 5,161 for search '"genomics"', query time: 0.06s Refine Results
  1. 4061

    Validation of <i>Monilinia fructicola</i> Putative Effector Genes in Different Host Peach (<i>Prunus persica</i>) Cultivars and Defense Response Investigation by Lucia Landi, Annamaria Lucrezia D’Ortenzio, Sarah Mojela Makau, Rita Milvia De Miccolis Angelini, Gianfranco Romanazzi

    Published 2025-01-01
    “…<i>M. fructicola</i> putative virulence factors have been predicted by genome investigations. The pathogen interaction with the host was validated. …”
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    Article
  2. 4062

    Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan... by Mohamed A. Lebdah, Amal A. M. Eid, Reham M. ElBakrey, Abd Elgalil. El-Gohary, Mohamed G. Seadawy, Mohamed R. Mousa, Hagar F. Gouda, Nehal I. A. Goda, Mostafa F. El-Hosseny, Ahmed S. El-tahlawy, Rokayya Sami, Rasha A. Al-Eisa, Sarah S. Helal

    Published 2025-01-01
    “…To our knowledge, the current study is pioneering to address the immunopathological impact of NGPV among naturally infected ducks confirmed with full genome sequencing and immunohistochemical identification worldwide.…”
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  3. 4063

    Refractory human cytomegalovirus infection without evidence of genetic resistance in the UL-54 and UL-97 genes in a pediatric hematopoietic stem cell transplant recipient: a case r... by Alejandra Pando-Caciano, Ketty Adid Escudero-Ramirez, Jackeline Carol Rodríguez-Torres, Holger Maita-Malpartida, Holger Maita-Malpartida

    Published 2024-02-01
    “…Furthermore, this case highlights the importance of using highly sensitive genetic tools to detect mutations associated with virus resistance in a broader range of the viral genome.…”
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    Article
  4. 4064

    Characterization of lysine acetyltransferase and deacetylase genes and their roles in anthocyanin biosynthesis in grape by Wen Tang, Feiyue Li, Danni Yang, Mengyu Xu, Jinggui Fang, Suwen Lu

    Published 2025-01-01
    “…In this study, 8 VvKATs and 14 VvKDACs were identified within the grape genome. Detailed analyses of their physicochemical properties, chromosomal distribution, phylogenetic synteny, evolutionary relationships, gene structures, and conserved motifs were conducted. …”
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  5. 4065

    Protein C deficiency with recurrent systemic thrombosis associated with compound heterozygous PROC missense variants by Mikio Shiba, Shuichiro Higo, Yu Morishita, Yasuhiro Ichibori, Yoshihiro Kin, Yasushi Sakata, Yoshiharu Higuchi

    Published 2025-02-01
    “…PCR amplification of genomic DNA spanning these exons followed by Sanger sequencing analysis revealed that the c.76G>A and the synonymous c.423G>T variants were in the same allele, whereas the c.1000G>A variant was on the opposite allele, indicating compound heterozygosity. …”
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    Article
  6. 4066

    Concordance between Immunohistochemistry and Microarray Gene Expression Profiling for Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Statuses in Breast Cancer Patients... by Ghina B. Fakhri, Reem S. Akel, Maya K. Khalil, Deborah A. Mukherji, Fouad I. Boulos, Arafat H. Tfayli

    Published 2018-01-01
    “…Gene expression profiling was performed using the GeneChip Human Genome U133 Plus 2.0 arrays (Affymetrix Inc). Immunohistochemical staining for estrogen receptor, progesterone receptor, and HER2 status was performed using standard methods at a CAP-accredited pathology laboratory. …”
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    Article
  7. 4067

    Role of bovine respiratory syncytial virus in etiology of respiratory diseases on milk farms by S. V. Koteneva, A. V. Nefedchenko, T. I. Glotova, A. G. Glotov

    Published 2021-03-01
    “…With the help of real-time PCR the virus genome was detected in lungs (13.1%), in exudate from trachea, bronchi and nasal sinuses (6.0%), in nasal discharge (4.0%) and in bronchi (1.7%). …”
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  8. 4068

    DNA barcoding: how many earthworm species are there in the south of West Siberia? by S. V. Shekhovtsov, N. E. Bazarova, D. I. Berman, N. A. Bulakhova, E. V. Golovanova, S. V. Konyaev, T. M. Krugova, I. I. Lyubechanskii, S. E. Peltek

    Published 2016-03-01
    “…This method employs short fragments of the genome to identify species, and allows one to work with specimens that cannot be identified by conventional techniques, as well as to search for new species and predict their phylogenetic affinities. …”
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    Article
  9. 4069

    Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis by Yang Ding, Shengyi Yang, Shasha Fan, Yi Tang, Yan Teng, Xiaohua Tao, Wei Lu

    Published 2022-01-01
    “…Genetic variants associated with vitamin D (n=304,181), 25-hydroxyvitamin D levels (n=401,460), and SLE (n=213,683) at genome-wide significance (P<5∗10−8) derived from large-scale publicly available GWAS data were used as instrumental variables. …”
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    Article
  10. 4070

    Autophagy-related long non-coding RNA MIR210HG plays a therapeutic role in hepatocellular carcinoma by Chaoqun Zhang, Dianxing Sun, Huifang Zhou, Chao Liu, Jie Ruan, Jiwen Kang, Ying Xie

    Published 2025-01-01
    “…Methods LncRNA MIR210HG expression and its correlation with survival outcomes in hepatocellular carcinoma patients were analyzed using data from The Cancer Genome Atlas (TCGA). Kaplan–Meier and Cox regression analyses were conducted to assess survival correlations. …”
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    Article
  11. 4071

    Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation by Xu-Dong Lian, Yong Guan, Yue Jiang, Dong-Heui Kwak, Mi-Kyung Lee, Zhun Li

    Published 2025-01-01
    “…Through comprehensive analyses, including 16S rRNA gene sequencing, whole-genome sequencing, and detailed morphological, physiological, and chemotaxonomic characterizations, these strains have been identified as new species within the genus Flavobacterium. …”
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  12. 4072

    Prenatal Identification and Molecular Characterization of Two Simultaneous De Novo Interstitial Duplications of Chromosomal Regions 7p22.1p21.1 and 15q24.1 by Sabrina C. Burn, Kali Swift, Maria Palmquist

    Published 2018-01-01
    “…Cytogenetic analysis of cultured amniocytes by conventional chromosome analysis, comparative genomic hybridization, and fluorescence in situ hybridization revealed two interstitial duplications of the chromosomal regions 7p22.1p21.1 and 15q24.1, leading to partial trisomy of 7p and 15q and karyotype 46,XY,dup(7)(p22.1-p21.1),dup (15)(q24.1). …”
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  13. 4073

    Proteome differences of dental stem cells between permanent and deciduous teeth by data-independent acquisition proteomics by Zhang Suping, Liu Yuqing, Dong Jin, Jiao Min, Gu Yongchun, Chen Liling, Yuan Na, Wang Jianrong, Yang Dezhao, Meng Fanwen

    Published 2025-01-01
    “…Subsequent Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses, along with protein–protein interaction network construction, revealed significant metabolic differences and key regulatory nodes. …”
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    Article
  14. 4074

    Validation of a one-step reverse transcription PCR detection method for Tobamovirus maculatessellati, in tomato (Solanum lycopersicum L.) and pepper (Capsicum annuum L.) by Chellappan Padmanabhan, Andrea Gilliard, Kai-Shu Ling, Yazmín Rivera

    Published 2025-01-01
    “…In this study, we report the validation of a previously described reverse transcription polymerase chain reaction (RT-PCR) assay that amplifies a 289 bp fragment of the coat protein coding region of ToMMV genome. This assay has 100% specificity for ToMMV. …”
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  15. 4075

    Antimicrobial Susceptibility of <i>Glaesserella parasuis</i> to Macrolides and Characterization of <i>erm</i>(T)-Carrying Mobile Elements on Chromosome by Peng Zhang, Changmin Li, Shuna Shang, Ting Huang, Junqi Liu, Qianwen Ge, Xiaoping Liao, Liangxing Fang, Yang Yu

    Published 2025-01-01
    “…Erythromycin-resistant isolates were sequenced using whole-genome sequencing. Further analysis of these sequences revealed the genetic basis of macrolide resistance in <i>G. parasuis</i>. …”
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  16. 4076

    A comprehensive overview of selective and novel fibroblast growth factor receptor inhibitors as a potential anticancer modality by Jain Nem Kumar, Tailang Mukul, Thangavel Neelaveni, Makeen Hafiz A., Albratty Mohammed, Najmi Asim, Alhazmi Hassan Ahmad, Zoghebi Khalid, Alagusundaram Muthumanickam, Jain Hemant Kumar, Chandrasekaran Balakumar

    Published 2024-03-01
    “…The arrival of comprehensive genome sequencing has accelerated the understanding of genetically aberrant advanced cancers and target identification for possible cancer treatment. …”
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    Article
  17. 4077

    Prevalence and Subtype Analysis of Blastocystis hominis Isolated from Patients in the Northeast of Iran by Mitra Salehi, Jalal Mardaneh, Hamid Reza Niazkar, Mohammadhaasan Minooeianhaghighi, Elahe Arshad, Fateme Soleimani, Alireza Mohammadzadeh

    Published 2021-01-01
    “…Samples were examined by a wet mount, and genomic DNA was extracted from positive samples. Also, PCR was done on the positive samples, and sequencing and phylogenetic analysis were subsequently performed. …”
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  18. 4078

    Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes by Xiaoling Yao, Xin Cai, Shaoqin Zhang, Yuzheng Yang, Xiangyan Yang, Wukai Ma, Zong Jiang

    Published 2025-02-01
    “…Abstract This study aims to explore the causal relationships between serum uric acid level and pulmonary arterial hypertension (PAH) using the Mendelian randomization (MR) approach, and to assess the therapeutic impacts of urate-lowering drugs on PAH. Utilizing published genome-wide association study (GWAS) data, we applied MR and colocalization analysis to assess the link between serum uric acid levesl and PAH across four GWAS datasets from two distinct European populations. …”
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  19. 4079

    Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly in Arabidopsis by Nguyen Thi Thuy, Hyun‐Jung Kim, Suk‐Whan Hong

    Published 2024-03-01
    “…Abstract Plant genomes contain numerous genes encoding chitinase‐like (CTL) proteins, which have a similar protein structure to chitinase belonging to the glycoside hydrolase (GH) family but lack the chitinolytic activity to cleave the β‐1,4‐glycosidic bond in chitins, polymers of N‐acetylglucosamine. …”
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  20. 4080

    Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping by Hannah L. Cornman, Martin P. Alphonse, Arbor Dykema, Alexander L. Kollhoff, Kevin K. Lee, Jaya Manjunath, Emily Z Ma, Varsha Parthasarathy, Junwen Deng, Thomas Pritchard, Anusha Kambala, Melika Marani, Kayla A. Parr, Javid P. Mohammed, Madan M. Kwatra, Jay H. Bream, Won Jin Ho, Shawn G. Kwatra

    Published 2025-01-01
    “…We found that the index patient had a novel form of erythroderma characterized by increased interleukin (IL)-13- and IL-17-producing γVδ2 T cells, basophils, and activated platelets. Whole-genome sequencing of PBMCs and immunofluorescence staining of skin biopsies revealed increased expression of Th2- (IL-13, IL-4Rα) and Th17-associated markers (IL-17, IL-17Rα) and non-functional mutations associated with Th2 and Th17 signaling, demonstrating that PBMCs can reflect cutaneous disease pathology. …”
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