Cell-marking techniques for cell lineage tracing by A. M. Yunusova, N. R. Battulin

“…This review focuses on modern methods for cell tracing with dyes and genetic constructs encoding protein reporters that mark cell lineages. Special focus is on genome-integrated tags (genetic labeling), such as viral and cellular barcoding. …”
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MeStanG—Resource for High-Throughput Sequencing Standard Data Sets Generation for Bioinformatic Methods Evaluation and Validation by Daniel Ramos Lopez, Francisco J. Flores, Andres S. Espindola

“…The simulator pipeline was evaluated by analyzing its output mock metagenomic samples containing known read abundances using read mapping, genome assembly, and taxonomic classification on three scenarios: a bacterial community composed of nine different organisms, samples resembling pathogen-infected wheat plants, and a viral pathogen serial dilution sampling. …”
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New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease by Ting Fang, Qiaoyan Liu, Xinxin Huangfu, Hongkai Zhu, Hongwen Sun, Liming Chen

“…Additionally, the study explored the targets of action for TPHP and DPHP using network toxicity analysis, conducted protein interaction analysis, and explored the functional aspects of action through Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Furthermore, the study identified key proteins involved in the action and conducted experimental verification by treating cells with TPHP and DPHP. …”
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Integrating AI into Cancer Immunotherapy—A Narrative Review of Current Applications and Future Directions by David B. Olawade, Aanuoluwapo Clement David-Olawade, Temitope Adereni, Eghosasere Egbon, Jennifer Teke, Stergios Boussios

“…Results: AI has significantly contributed to identifying biomarkers that predict immunotherapy efficacy by analyzing genomic, transcriptomic, and proteomic data. It also optimizes combination therapies by predicting the most effective treatment protocols. …”
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Testing and identification of bovine viral diarrhea virus isolates recovered in Russia between 2019 and 2022 by R. I. Bubyakin, S. V. Kononova, I. N. Shumilova, O. P. Byadovskaya, A. O. Krotova, A. V. Kononov

“…Based on the analysis of the nucleotide sequence of genome 5’-untranslated region (5’-UTR) fragment, these isolates were classified as belonging to three genotypes of the virus. …”
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Epigenetics and Inflammatory Markers: A Systematic Review of the Current Evidence by Valentina Gonzalez-Jaramillo, Eliana Portilla-Fernandez, Marija Glisic, Trudy Voortman, Mohsen Ghanbari, Wichor Bramer, Rajiv Chowdhury, Tamar Nijsten, Abbas Dehghan, Oscar H. Franco, Jana Nano

“…This review supports an association between epigenetic marks and inflammation, suggesting hypomethylation of the genome. Important gaps in the quality of studies were reported such as inadequate sample size, lack of adjustment for relevant confounders, and failure to replicate the findings. …”
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Characterization of Broad Spectrum Bacteriophage vB ESM-pEJ01 and Its Antimicrobial Efficacy Against Shiga Toxin-Producing <i>Escherichia coli</i> in Green Juice by Eun Jeong Park, Seungki Lee, Jong Beom Na, Ye Bin Kim, Kee Man Lee, Seon Young Park, Ji Hyung Kim

“…Moreover, the phage demonstrated strong anti-biofilm efficacy even at low concentrations. Genomic analysis revealed that the phage was similar to the well-characterized RB49 phage (T4-like phage) but possesses distinct host-specificity-related genes that potentially contribute to its extensive host range. …”
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Genotypic Characterization of Azotobacteria Isolated from Argentinean Soils and Plant-Growth-Promoting Traits of Selected Strains with Prospects for Biofertilizer Production by Esteban Julián Rubio, Marcela Susana Montecchia, Micaela Tosi, Fabricio Darío Cassán, Alejandro Perticari, Olga Susana Correa

“…The genetic diversity among 31 putative Azotobacter isolates obtained from agricultural and non-agricultural soils was assessed using rep-PCR genomic fingerprinting and identified to species level by ARDRA and partial 16S rRNA gene sequence analysis. …”
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Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells by Beibei Chen, Bo Zhang, Huaxia Luo, Jiao Yuan, Geir Skogerbø, Runsheng Chen

“…Here, we show distinct genome-wide sub-cellular localization distribution profiles of small noncoding RNAs in human breast cancer cells. …”
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Chloroplast DNA Diversity of Tunisian Barley Landraces as Revealed by cpSSRs Molecular Markers and Implication for Conservation Strategies by Marwa Snoussi, Leila Riahi, Mériam Ben Romdhane, Ahmed Mliki, Nejia Zoghlami

“…Information on genetic variation within the chloroplast genome is of great interest to ensure an efficient conservation strategy that takes into account the preservation of the various maternal lineages of Tunisian barley.…”
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Conserved Nuclear Localization Signal in NS2 Protein of Bombyx Mori Bidensovirus: A Potential Invertebrate ssDNA Virus Trait by Qian Yu, Jiaxin Yan, Ying Chen, Jinfeng Zhang, Qi Tang, Feifei Zhu, Lindan Sun, Shangshang Ma, Xiaoyong Liu, Keping Chen, Qin Yao

“…Bombyx mori bidensovirus (BmBDV), a significant pathogen in the sericulture industry, holds a unique taxonomic position due to its distinct segmented single-stranded DNA (ssDNA) genome and the presence of a self-encoding DNA polymerase. …”
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Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes by Wei Dai, Haicong Zhu, Junhong Chen, Hui Chen, Dingzhen Dai, Jian Wu

“…Besides the shared metabolic pathways and biosynthesis of secondary metabolites, biosynthesis of amino acids was the most abundant Kyoto Encyclopedia of Genes and Genomes (KEGG) function in young pigeons, while microbial metabolism in diverse environments was abundant in older pigeons. …”
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The effect of tumour necrosis factor-α (TNF-α) muteins on human neutrophils in vitro by H. Tchorzewski, K. Zeman, J. Kantorski, E. Paleolog, M. Kahan, M. Feldmann, M. Kwinkowski, P. Guga, B. Szymanska, P. Parniewski, A. Wilk, J. Jarosz

“…To verify the suggestion that the receptor binding domain includes the region close to the N-terminus of the TNF-α molecule, four TNF-α derivatives termed muteins were constructed, using a synthetic cDNA fragment substituting the N-terminal 3–7 selected hydrophilic or hydrophobic amino acids in the original TNF-α genomic DNA. Binding of muteins to PMN was assessed using monoclonal antibodies recognizing either the 55 kDa (p55) or the 75 kDa (p75) TNF receptor subtypes. …”
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Genetic advancements in breast cancer treatment: a review by Marzieh Shokoohi, Sadaf Sedaghatshoar, Homaira Arian, Milad Mokarami, Fatemeh Habibi, Fatemeh Bamarinejad

“…Personalized medicine, guided by genomic profiling, further enhances treatment precision by identifying patient-specific mutations, such as BRCA1 and BRCA2, allowing for more tailored and effective interventions. …”
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Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL by Yue-miao Zhang, Fa-juan Cheng, Xu-jie Zhou, Yuan-yuan Qi, Ping Hou, Ming-hui Zhao, Hong Zhang

“…As elevated ATG5 expression was observed in systemic lupus erythematosus (SLE), the study was conducted to analyze the genome-wide genetic regulatory mechanisms associated with ATG5 expression in a Chinese population with lupus nephritis (LN). …”
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GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding by Jiahui Zou, Meijun Jiang, Rong Xiao, Huimin Sun, Hailong Liu, Thomas Peacock, Shaoyu Tu, Tong Chen, Jinli Guo, Yaxin Zhao, Wendy Barclay, Shengsong Xie, Hongbo Zhou

“…In this study, we conduct a comprehensive genome-wide CRISPR/Cas9 knockout screen utilizing EA H1N1 SIV in porcine kidney cells. …”
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A multi-trait approach identified 7 novel genes for back pain by Nadezhda M. Belonogova, Elizaveta E. Elgaeva, Irina V. Zorkoltseva, Anatoliy V. Kirichenko, Gulnara R. Svishcheva, Maxim B. Freidin, Frances M. K. Williams, Pradeep Suri, Tatiana I. Axenovich, Yakov A. Tsepilov

“…Less than half of this can be explained by known genetic variants identified in genome-wide association studies. Objectives:. We applied a powerful multi-trait and gene-based approach to association analysis of BP to identify novel genes associated with BP. …”
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Comprehensive Analysis of Gene Signatures of m6ARNA Methylation Regulators in Lung Adenocarcinoma and Development of a Risk Scoring System by Chundi Gao, Huayao Li, Wenzhe Ma, Qiming Zhang, Cun Liu, Lijuan Liu, Jing Zhuang, Changgang Sun

“…We systematically studied correlations among important M6A methylation regulators, tumor mutational burden (TMB), and immune infiltration in clinical and sequencing data from the LUAD cohort of the cancer genome map (TCGA). The molecular subtype clusters 1 and 2 were identified by the consensus clustering of 16 M6A regulatory factors. …”
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Novel relatives of Mecsek Mountains mammarenavirus (family Arenaviridae) in hedgehogs living in different sampling areas in Hungary by Károly Takáts, Péter Pankovics, Benigna Balázs, Ákos Boros, Róbert Mátics, Gábor Reuter

“…In this study, 59 faecal specimens from Northern white-breasted hedgehogs (Erinaceus roumanicus) from different geographic regions in Hungary were investigated for mammarenavirus presence and complete genome characterization using newly designed screening primers by RT-semi-nested PCR and sequencing methods. …”
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Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response by Lisa Teichmann, Sam Luitwieler, Johan Bengtsson-Palme, Benno ter Kuile

“…Ciprofloxacin, enrofloxacin, and moxifloxacin exposures led to the most evident reliance on the SOS response for resistance, whereas levofloxacin exposed cultures showed less dependency. Whole genome analysis indicated distinct genetic changes associated with each fluoroquinolone, highlighting potential different pathways and mechanisms involved in resistance. …”
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