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3761
NOS2 as a prognostic biomarker for early-onset colorectal cancer based on public data and clinical validation analysis
Published 2025-02-01“…EOCRC from The Cancer Genome Atlas Program (TCGA) database and Gene Expression Mapping (GEO) database were used to screen biomarkers for prognosis and treatment guidance. …”
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3762
Mitogenomic Phylogenetic Analyses Reveal New Insights into the Taxonomy and Evolution of Parnassiinae Swallowtail Butterflies (Lepidoptera: Papilionidae)
Published 2024-12-01“…Mitochondrial genomes provide powerful insights into insect phylogeny and molecular evolution, aiding in the clarification of complex taxonomic relationships. …”
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3763
De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii
Published 2025-01-01“…Abstract Understanding the genomic consequences of hybridization is an essential research focus in global change biology. …”
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3764
Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets
Published 2017-01-01“…Our research group recently described genome-wide characterization of motor cortex samples from sporadic ALS (SALS) patients, revealing the existence of molecular and functional heterogeneity in SALS. …”
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3765
A CACTA-like transposon in the Anthocyanidin synthase 1 (Ans-1) gene is responsible for apricot fruit colour in the raspberry (Rubus idaeus) cultivar 'Varnes'.
Published 2025-01-01“…By performing RNASeq, we revealed differential expression patterns in the apricot-fruited 'Varnes' for genes in the anthocyanin biosynthesis pathway and following whole genome sequencing using long-read Oxford Nanopore Technologies sequencing, we identified a CACTA-like transposable element (TE) in the second exon of the Anthocyanidin synthase (Ans) gene that caused a truncated predicted ANS protein. …”
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3766
RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome
Published 2025-02-01“…This underscores the importance of RECQ4-MUS81 in safeguarding genome integrity and suggests potential implications for human disease. …”
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3767
Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology
Published 2021-01-01“…Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were carried out via DAVID. …”
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3768
Determination of FMDV 146S particle concentration by spectrometric method during viral RNA quantification
Published 2021-01-01“…Tests of the positive control demonstrated 99.0–99.6% compatibility of actual and expected results. FMDV genome and 146S particles were not detected in the negative control, and that was in line with expectations.…”
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3769
Nuclear mRNA export
Published 2024-09-01“…While these mechanisms are generally conserved across eukaryotes, significant differences exist between yeast and higher eukaryotic cells, particularly due to the more genome complexity of the latter. …”
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3770
The emerging roles of aberrant alternative splicing in glioma
Published 2025-02-01“…AS is a process that produces, from a single genomic sequence, several mature messenger RNAs. Splicing of pre-messenger RNAs concerns at least 95% of transcripts and constitutes an important mechanism in gene expression regulation. …”
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3771
NHÂN DÒNG VÀ NGHIÊN CỨU MỨC ĐỘ METHYL HÓA VÙNG ICR (Imprinting control region) TRÊN LOCUS Igf2/H19 Ở CHUỘT (Mus musculus)
Published 2012-11-01“…Epigenetic (ngoại di truyền) là hiện tượng trong quá trình in dấu hệ gen (genome imprinting) mà chỉ một allele bố mẹ được biểu hiện tùy thuộc vào nguồn gốc allele đó. …”
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3772
Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population
Published 2014-01-01“…Diabetes is a serious global health problem. Large-scale genome-wide association studies identified loci for type 2 diabetes mellitus (T2DM), including adiponectin (ADIPOQ) gene and transcription factor 7-like 2 (TCF7L2), but few studies clarified the effect of genetic polymorphisms of ADIPOQ and TCF7L2 on risk of T2DM. …”
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3773
Connecting electronic health records to a biomedical knowledge graph to link clinical phenotypes and molecular endotypes in atopic dermatitis
Published 2025-01-01“…Through our analysis, we identified seven subgroups of patients each characterized by clinical and genomic characteristics.…”
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3774
A SH3b domain-containing peptidoglycan recognition protein from Magallana gigas with broad recognition spectrum
Published 2025-06-01“…In the present study, nine MgPGRP genes were identified in the updated genome of Magallana gigas, and the cDNA of MgPGRP5 which was consisted of a SH3b and a PGRP domain was cloned. …”
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3775
Leptospira and Inflammation
Published 2012-01-01“…The recent sequencing of the Leptospira genome has increased our knowledge about this pathogen. …”
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3776
D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming
Published 2025-02-01“…Oncometabolites jeopardize genome stability and DNA repair by affecting high-order chromatin structure.…”
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3777
In Vitro Analyses Reveal the Effect of Synthetic Cytokinin Forchlorfenuron (FCF) on a Septin-Like Protein of Taeniid Cysticerci
Published 2019-01-01“…Cytokinin forchlorfenuron (FCF), a synthetic cytokinin, has been used specifically for the characterization of septins. In spite of genomic evidence of their existence, nothing is known about septin filaments in taeniid cestodes. …”
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3778
A Hybrid Approach of Using Wavelets and Fuzzy Clustering for Classifying Multispectral Florescence In Situ Hybridization Images
Published 2006-01-01“…Multicolor or multiplex fluorescence in situ hybridization (M-FISH) imaging is a recently developed molecular cytogenetic diagnosis technique for rapid visualization of genomic aberrations at the chromosomal level. By the simultaneous use of all 24 human chromosome painting probes, M-FISH imaging facilitates precise identification of complex chromosomal rearrangements that are responsible for cancers and genetic diseases. …”
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3779
Gene Expression Changes in Venous Segment of Overflow Arteriovenous Fistula
Published 2013-01-01“…Total RNA was extracted from the venous tissue samples, and gene expression between the 2 groups was compared using Whole Human Genome DNA microarray 44 K. Microarray data were analyzed by GeneSpring GX software and Ingenuity Pathway Analysis. …”
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3780
First detection of recombinant variant of African swine fever virus in the Russian Federation (brief communication)
Published 2024-09-01“…As part of extensive molecular and genetic research into African swine fever virus isolates circulating in Russia, a recombinant variant with a mosaic genome structure has been identified. The one that caused an outbreak on a pig farm in the Primorsky Krai, in 2023. …”
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