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3581
Research Note: Novel reassortant avian influenza A(H9N2) Viruses in Wild Birds in Shanghai, China, 2020–2023
Published 2025-03-01“…To better understand the genetic characteristics of these H9N2 viruses in Shanghai, the whole genome sequences were analyzed. Phylogenetical analysis showed that the nine H9N2 viruses have undergone complicated reassortment with waterfowl viruses along the East Asian-Australasian flyways. …”
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3582
TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8+ T cell activation
Published 2025-01-01“…Here, we show extensive changes in the three-dimensional genome during CD8+ T cell activation, associated with changes in gene transcription. …”
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3583
Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients
Published 2017-01-01“…In this study, human whole genome microarrays identified 2898 and 4493 differentially expressed genes (DEGs) in DM and DPN patients, respectively. …”
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3584
Characterization of eDNA from the Clinical Strain Acinetobacter baumannii AIIMS 7 and Its Role in Biofilm Formation
Published 2012-01-01“…An assessment of the characteristics of the eDNA with respect to size, digestion pattern by DNase I/restriction enzymes, and PCR-sequencing, indicates a high similarity with genomic DNA. Role of eDNA in static biofilm formed on polystyrene surface was evaluated by biofilm augmentation assay using eDNA available in different preparations, for example, whole cell lysate, cell-free supernatant, MV suspension, and purified eDNA. …”
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3585
Aging, cancer, and autophagy: connections and therapeutic perspectives
Published 2025-01-01“…As organisms age, cellular stress, genomic instability, and an accumulation of senescent cells create a pro-inflammatory environment conducive to cancer development. …”
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3586
Optimized convolutional neural network using African vulture optimization algorithm for the detection of exons
Published 2025-01-01“…Abstract The detection of exons is an important area of research in genomic sequence analysis. Many signal-processing methods have been established successfully for detecting the exons based on their periodicity property. …”
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3587
Frequency of Drug Resistance Gene Amplification in Clinical Leishmania Strains
Published 2010-01-01“…Gene amplification is therefore a common phenomenon in wild strains concurring to Leishmania genomic plasticity. This finding, which corroborates results of experimental studies, supports a better understanding of metal resistance selection and spreading in endemic areas.…”
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3588
Behçet's Disease (Adamantiades-Behçet's Disease)
Published 2011-01-01“…Bes-1 gene encoded partial S. sanguinis genome which is highly homologous with retinal protein, and 65 kD heat shock protein (Hsp-65) released from streptococci is playing an important role with human Hsp-60 in the pathogenesis of ABD. …”
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3589
The Ecology and Evolutionary Biology of Cancer: A Review of Mathematical Models of Necrosis and Tumor Cell Diversity
Published 2005-02-01“…Recent evidence elucidating the relationship between parenchyma cells and otherwise ''healthy'' cells in malignant neoplasms is forcing cancer biologists to expand beyond the genome-centered, ''one-renegade-cell'' theory of cancer. …”
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3590
Cell migration in dense microenvironments
Published 2023-09-01“…The nucleus has been viewed as a passenger during cell migration that functions merely to protect the genome. However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating extracellular mechanical inputs into intracellular signaling. …”
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3591
Chorioamnionitis and Lung Injury in Preterm Newborns
Published 2013-01-01“…Genetic susceptibility to BPD is an evolving area of research and several studies have directly related the risk of BPD to genomic variants. There is a substantial heterogeneity across the studies in the magnitude of the association between chorioamnionitis and BPD, and whether or not the association is statistically significant. …”
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3592
Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients
Published 2020-01-01“…Saliva was collected from 15 OSAS patients and nine healthy controls, and bacterial genomic DNA was extracted for 16S rRNA amplicon sequencing based on the Illumina platform. …”
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3593
Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions
Published 2024-12-01“…By integrating traditional ethnobotanical knowledge with modern genomic and bioinformatic approaches, this study underscores the importance of plant RiPPs as a resource for developing innovative cancer treatments. …”
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3594
Role of plasmids in antibiotic resistance in clinical infections and implications for epidemiological surveillance: a review
Published 2024-12-01“…Recent technologies like replicon typing and whole genome sequencing (WGS) have become the gold standard for molecular epidemiology of plasmids for the detection and control of epidemics in clinical settings. …”
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3595
LncRNAs: New Players in Apoptosis Control
Published 2014-01-01“…The discovery that the mammalian genome is largely transcribed and that almost half of the polyadenylated RNAs is composed of noncoding RNAs has attracted the attention of the scientific community. …”
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3596
Higher-Order Chromatin Regulation of Inflammatory Gene Expression
Published 2017-01-01“…This article will review emerging evidence on the genome organization hierarchy underlying the inflammatory response.…”
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3597
Kernel type-based entries are efficient to develop a core collection of maize (Zea mays L.)
Published 2025-01-01“…Here we showed that kernel type based entries are useful for developing a core collection representing large genetic variation. Based on genome-wide association studies (GWAS) of yellow kernel color and six yield related phenotypes, we found that y1 gene is responsible determinant of yellow color kernel and several genes were revealed to be involved in the yield-related phenotypes. …”
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3598
Long journey of 16S rRNA‐amplicon sequencing toward cell‐based functional bacterial microbiota characterization
Published 2024-09-01“…Furthermore, we present the prospects for further technical development, including the combined use of high‐throughput methods and other informative analyses, such as whole‐genome sequencing in the common unit of the cell, which enables bacterial microbiota characterization based on both the number of cells and their functions.…”
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3599
How does the mode of evolutionary divergence affect reproductive isolation?
Published 2023-01-01“…When divergent populations interbreed, the outcome will be affected by the genomic and phenotypic differences that they have accumulated. …”
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3600
Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus
Published 2008-01-01“…We used microarray-based comparative genomic hybridization to identify open reading frames (ORFs) present in two sequenced invasive strains, but absent or divergent in tester strains. …”
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