A study on the codon usage bias of arenavirus common genes by Pablo Daniel Thomas, María Florencia Ferrer, Mauricio J. Lozano, Ricardo Martín Gómez

“…The codon usage bias between the different genera has not yet been studied comparatively.MethodsWe retrieved the arenavirus genome sequences from public databases and used bioinformatics tools to compare the codon usage bias between the different genera for the GPC, NP and L proteins, common to all arenaviruses.Results and discussionHartmaniviruses show a larger codon usage bias, which can be partially explained by mutational bias. …”
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Exploring the Impact of Large Language Models on Disease Diagnosis by Ibrahim Almubark

“…This review shows that LLMs have utilized a variety of medical data sources, including general medical databases, specialized documents, medical images, and genomic data. Moreover, the focus of these LLMs spans a broad spectrum of healthcare fields, addressing chronic conditions, respiratory diseases, cancer, and rare diseases. …”
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PPAR𝛾, PTEN, and the Fight against Cancer by Rosemary E. Teresi, Kristin A. Waite

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The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response by Pamela C. Ronald

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Genetics and Epigenetics of Parkinson's Disease by Fabio Coppedè

“…The majority of PD cases are however sporadic “idiopathic” forms, and the recent application of genome-wide screening revealed almost 20 genes that might contribute to disease risk. …”
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Implementation of Accurate and Fast DNA Cytometry by Confocal Microscopy in 3D by Lennert S. Ploeger, André Huisman, Jurryt van der Gugten, Dionne M. van der Giezen, Jeroen A. M. Beliën, Abdelhadi Y. Abbaker, Hub F. J. Dullens, William Grizzle, Neal M. Poulin, Gerrit A. Meijer, Paul J. van Diest

“…Background: DNA cytometry is a powerful method for measuring genomic instability. Standard approaches that measure DNA content of isolated cells may induce selection bias and do not allow interpretation of genomic instability in the context of the tissue. …”
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Genetic Variation Analysis of Hsp101 Gene in Common Wild Rice and Asian Cultivated Rice Germplasm Resources by Yue LIU, Liqun JIANG, Shuwei LYU, Bingrui SUN, Chen LI, Qing LIU, Hang YU

“…【Methods】The rice germplasm resources of 3 325 genome sequencing data were obtained through retrieval and collation, and single nucleotide polymorphism (SNP) and small fragment insertion and deletion (InDel) variations were revealed by genome resequencing data analysis. …”
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Characterizing immune biomarkers and effector CD8+ T-cell exhaustion in pancreatic adenocarcinoma via single-cell RNA sequencing profiling by Rawaa AlChalabi, Raghda Makia, Semaa A. Shaban, Ahmed AbdulJabbar Suleiman

“…Methods: We employed a multi-omics approach, integrating single-cell RNA sequencing data with whole genome sequencing to identify dysregulated exhaustion-related immune markers in CD8+ T-cells in PDAC. …”
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Systematic review of multidrug-resistant Klebsiella pneumoniae in the Arabian Peninsula: molecular epidemiology and resistance patterns by Enaam K. Idrees, Enaam K. Idrees, Marwh G. Aldriwesh, Marwh G. Aldriwesh, Marwh G. Aldriwesh, Manal M. Alkhulaifi, Majed F. Alghoribi, Majed F. Alghoribi, Majed F. Alghoribi

“…Limited molecular and genome-based investigations hinder comprehensive AMR surveillance. …”
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Co-Infection of <i>Culex tarsalis</i> Mosquitoes with Rift Valley Fever Phlebovirus Strains Results in Efficient Viral Reassortment by Emma K. Harris, Velmurugan Balaraman, Cassidy C. Keating, Chester McDowell, J. Brian Kimble, Alina De La Mota-Peynado, Erin M. Borland, Barbara Graham, William C. Wilson, Juergen A. Richt, Rebekah C. Kading, Natasha N. Gaudreault

“…Furthermore, we observed preferential inclusion of genomic segments from the three parental strains among the reassorted viruses. …”
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The miR-146a SNP Rs2910164 and miR-155 SNP rs767649 Are Risk Factors for Non-Small Cell Lung Cancer in the Iranian Population by Neda K. Dezfuli, Ian M. Adcock, Shamila D. Alipoor, Sharareh Seyfi, Babak Salimi, Maryam Mafi Golchin, Neda Dalil Roofchayee, Mohammad Varhram, Esmaeil Mortaz

“…Allele frequencies from the genomic DNA of blood cells were studied using PCR-RFLP and their association with the risk of lung cancer was evaluated. …”
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Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma by Huai-Yu Wu, Shu-Ya Cao, Zheng-Gang Xu, Tian- Wang, Gu-Wei Ji, Ke Wang

“…Methods Using data from The Cancer Genome Atlas Program (TCGA) as a training cohort and data from International cancer genome consortium (ICGC) as a testing cohort. …”
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Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas by Junhao Zhang, Lingbo Li, Aiwei Tang, Chucheng Wang, Yupeng Wang, Yongqi Hu, Guangting He, Guangting He, Wangjun Liao, Wangjun Liao, Wangjun Liao, Rui Zhou

“…Additional glioma-specific datasets (Chinese Glioma Genome Atlas, GlioVis, GSE43378, and GSE182109) were also collected to validate the transcriptional characteristics of HATs and HDACs in gliomas. …”
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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…NMM exhibited a minimum inhibitory concentration (MIC) of 5 μM against S. aureus USA300, impacting cell division and the cell wall by repressing the expressions of genes in the division cell wall (dcw) gene cluster. Genome-wide bioinformatics analysis of G4 motifs and their mapping on S. aureus genome, identified the presence of G4-motif in the promoter of mraZ, a conserved master regulator of the dcw cluster regulating the coordinated cell division and cell wall synthesis. …”
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Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma by Hengchang Liu, Jialiang Liu, Xu Guan, Zhixun Zhao, Pu Cheng, Haipeng Chen, Zheng Jiang, Xishan Wang

“…Methods Data on gene expression and mutations in READ were obtained from The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases. …”
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HIV-1 transcription start sites usage and its impact on unspliced RNA functions in people living with HIV by Saiful Islam, Frank Maldarelli, Olga A. Nikolaitchik, Zetao Cheng, Robert Gorelick, Maria A. Nikolaitchik, Vinay K. Pathak, Wei-Shau Hu

“…ABSTRACT HIV-1 unspliced RNA serves two distinct functions during viral replication: it is packaged into particles as the viral genome, and it is translated to generate Gag/Gag-Pol polyproteins required for virus assembly. …”
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The Identification of Molecular Ploidy Status of Abnormal Pronuclear Zygotes Reveals a Significant Number of Euploid Blastocysts Available for Conception by Blair R. McCallie, Mary E. Haywood, Lauren N. Henry, Rachel M. Lee, William B. Schoolcraft, Mandy G. Katz-Jaffe

“…Biopsied trophectoderm cells were then lysed, and the isolated DNA was whole-genome amplified followed by library preparation. …”
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The Immunohistochemical Prognostic Value of Nuclear and Cytoplasmic Silent Information Regulator 1 Protein Expression in Saudi Patients with Breast Cancer by Bayan Alharbi, Alia Aldahlawi, Mourad Assidi, Fatemah Basingab, Kawther Zaher, Jehan Alrahimi, Sara Mokhtar, Jaudah Al-Maghrabi, Abdelbaset Buhmeida, Kaltoom Al-Sakkaf

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Epidemiology of pediatric dengue virus infection, Scenario from a tertiary level hospital in Bangladesh by Kinkar Ghosh, Selim Reza Tony, Khaleda Islam, Reaz Mobarak, Md. Jahangir Alam, Md. Kamruzzaman, Sumaira Alam, Muhammad Talha, Abdullah Al Faisal, Nahidul Islam, Md Mobarok Hossain, Mst. Noorjahan Begum, Mustafizur Rahman

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Detection of genetic sex using a qPCR-based method in the bigfin reef squid (Sepioteuthis lessoniana) by Yi-Chien Lee, Li-Lun Tang, Yu-Chen Yeh, Hau-Wen Li, Huei-Mien Ke, Cheng-Ju Yang, Chun-I Chiang, Chia-Hui Wang, Yung-Che Tseng, Ching-Fong Chang, Isheng Jason Tsai, Guan-Chung Wu

“…Analysis of the female and male genome coverage along the assembly confirms a ZZ/Z0 female hemizygous sex-determination system in bigfin reef squid. …”
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