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3261
Molecular characterization and lineage analysis of canine astrovirus strains from dogs with gastrointestinal disease in Ecuador based on ORF-2 gene analysis
Published 2025-02-01“…Canine Astrovirus (CaAstV) part of the Astroviridae family and genus Mamastrovirus, is a linear RNA virus with a genome of approximately 6.6 kb with three open reading frames (ORF): ORF1a and ORF1b, which code for the most conserved non-structural proteins, and ORF2, which code for the capsid protein, the most variable region of the genome. …”
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3262
Identification and subcellular localization of proteins that interact with Duck plague virus pUL14 in infected host cells
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses revealed that the identified proteins could be assigned to several different subcellular locations and functional classes. …”
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3263
T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses
Published 2024-07-01“…Bulk microbiome, as well as virome-enriched shotgun sequencing only reveals the double-stranded DNA (dsDNA) content of a given sample, unless specific treatments are applied. However, genomes of viruses often consist of a circular single-stranded DNA (ssDNA) molecule. …”
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3264
Search for signals of positive selection of circadian rhythm genes <i>PER1</i>, <i>PER2</i>, <i>PER3</i> in different human populations
Published 2024-10-01“…Data were analyzed using publicly available data from the 1000 Genomes Project for 23 populations. The Extended Haplotype Homozygosity Score statistical method was chosen to search for traces of selection. …”
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3265
Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury
Published 2024-12-01“…Gene Ontology (GO) functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of DE lncRNAs and mRNAs were subsequently carried out to explore crucial biological processes and signaling pathways. …”
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3266
Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development
Published 2012-01-01“…The HIV-1 genome is malleable and a difficult target tot vaccinate against. …”
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3267
Integrins identified as potential prognostic markers in osteosarcoma through multi-omics and multi-dataset analysis
Published 2025-01-01“…The IRS’s utility in predicting overall survival was confirmed using data from The Cancer Genome Atlas, underscoring its potential in personalized cancer management.…”
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3268
Management of Primary Sclerosing Cholangitis: Conventions and Controversies
Published 2012-01-01“…While the pathogenesis of PSC has not been fully elucidated, emerging evidence supports roles for the innate and adaptive immune systems, and genome-wide analyses have identified several genetic associations. …”
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Alteration of Immune-Mechanisms by Human Microbiota and Development and Prevention of Human Diseases
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A catechol-O-methyltransferase genetic variant impacts functional movement in tactical athletes.
Published 2025-01-01“…In resource constrained settings, genomic modeling may help to direct limited assets to at-risk subgroups (for screening purposes). …”
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3278
Changing of expression actinbinding proteins in the kidney under dehydration
Published 2018-04-01“…The presence of the normal vasopressin gene in the genome, regardless of transitory expression level and secretion of hormone, is a factor of lower tropomyosin in the kidney. …”
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Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy
Published 2022-09-01“…Significantly, ~20% of malignancies harbor alterations in >1 of these subunits, making the genes encoding SWI/SNF family members among the most vulnerable to genomic aberrations in cancer. ARID1A is the largest subunit of the SWI/SNF complex and is altered in ~40%–50% of ovarian clear cell cancers and ~15%–30% of cholangiocarcinomas, in addition to a variety of other malignancies. …”
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3280
Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia
Published 2023-08-01“…Strain MUM 203JT has a genome size of 6,446,886 bp, with DNA G + C content of 72.26 mol%. …”
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