Exploring Unique Extracellular Vesicles Associated Signatures: Prognostic Insights, Immune Microenvironment Dynamics, and Therapeutic Responses in Pancreatic Adenocarcinoma by Kai Nan, Ming Zhang, Zilong Geng, Yuankai Zhang, Lin Liu, Zhi Yang, Peng Xu

“…Initially, we identified differentially expressed lncRNAs (DELs) from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) project datasets. …”
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Mining Prognostic Biomarkers of Thyroid Cancer Patients Based on the Immune-Related Genes and Development of a Reliable Prognostic Risk Model by Hongjun Fei, Xu Han, Yanlin Wang, Shuyuan Li

“…According to The Cancer Genome Atlas (TCGA) cohort, we developed a least absolute shrinkage and selection operator (LASSO) regression prognostic model and performed validation analyses regard to the predictive value of the model in internal (TCGA) and external (International Cancer Genome Consortium) cohorts respectively. …”
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ADF1 and BEAF-32 chromatin proteins affect nucleosome positioning and DNA decompaction in 61C7/C8 interband region of Drosophila melanogaster polytene chromosomes by M. B. Schwartz (Berkaeva), T. E. Pankova, S. A. Demakov

“…Under these conditions, the genome retains its functionality due to the dynamic and uneven DNA compaction along the chromatin fiber. …”
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Identification of two new genetic loci for high-resolution genotyping of Enterocytozoon bieneusi by Meng Xinan, Ou Yonglin, Jiang Wen, Guo Yaqiong, Xiao Lihua, Feng Yaoyu, Li Na

“…In this study, comparison of a clinical genome sequence (C44566) with the whole genome sequence of an E. bieneusi isolate (H348) in GenBank led to the selection of the hypothetical protein 1 (hp1) and tubulin 1 (tub1) loci. …”
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LncRNA MANCR is downregulated in non-small cell lung cancer and predicts poor survival by Yunming Tao, Jie Liu, Wenxiao Qiu, Yuanyuan Li

“…Abstract Background It is known that genomic instability contributes to cancer development. …”
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Epidemiological monitoring of avian influenza in the Republic of Crimea in 2019–2020 by D. V. Gadzevich, S. I. Danylchenko, N. V. Vorotilova, M. A. Pasunkina, V. A. Uppe, V. N. Irza, M. S. Volkov, N. G. Zinyakov

“…In 2019, the AIV type A (H9) genome was detected in one fecal sample taken from wild birds near Kuchuk-Adzhigol Lake in Feodosia Urban Okrug. …”
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Modern issues of sugar beet (<i>Beta vulgaris</i> L.) hybrid breeding by S. D. Karakotov, I. V. Apasov, A. A. Nalbandyan, E. N. Vasilchenko, T. P. Fedulova

“…It has been found that DNA markers of the sugar beet mitochondrial genome belonging to the TR minisatellite family (TR1 and TR3) enable reliable enough identification of haploid microclonal plants as MSor O-type forms. …”
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Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein. by Qian Qiu, Zihan He, Jing Liu, Huijun Xu, Jinyu Wang, Nannan Liu, Ning Kang, Shaokun Pan, Weien Yu, Zixiang Gao, Shimei Zhang, Yang Yang, Qiang Deng, Youhua Xie, Jiming Zhang, Zhongliang Shen

“…We recently characterized homeobox protein MSX-1 (MSX1) as a host restriction factor that inhibits HBV gene expression and genome replication by directly binding to HBV enhancer II/core promoter (EnII/Cp) and suppressing its promoter and enhancer activities. …”
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GWAS of a soybean breeding collection from South East and South Kazakhstan for resistance to fungal diseases by A. Zatybekov, S. Abugalieva, S. Didorenko, A. Rsaliyev, Y. Turuspekov

“…One of the main problems of soybean production is fungal diseases causing yields losses of up to 30 %. Modern genomic studies can be applied to facilitate efficient breeding research for improvement of soybean fungal disease tolerance. …”
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Exome sequencing of UK birth cohorts [version 2; peer review: 2 approved, 1 approved with reservations] by Petr Danecek, Amy Hough, John Wright, Karen Ho, Nicholas J. Timpson, Sarah J. Lindsay, Davide Bonfanti, Daniel S. Malawsky, Rafaq Azad, Deborah Plowman, Sara Widaa, Gemma Shireby, Emla Fitzsimons, David Bann, Matthew E. Hurles, Hilary C. Martin, Susan M. Ring, Dan Mason, Michael A. Quail, Wei Huang, Vivek Iyer, Mahmoud Koko, Iaroslav Popov, Laurie Fabian, Gennadii Zakharov, Ruth Y. Eberhardt, Emma E. Wade, Qin Qin Huang

“…This rich source of longitudinal data, when combined with genomic data, offers the scientific community valuable insights ranging from population genetics to applications across the social sciences. …”
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Current concepts in the pathogenesis of spondyloarthritis by Nibha Jain, Arumugam Moorthy

“…The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us understand and postulate various theories. …”
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The Effect of Mitochondrial Dysfunction on Cytosolic Nucleotide Metabolism by Claus Desler, Anne Lykke, Lene Juel Rasmussen

“…Mitochondrial dysfunction has been linked to genomic instability, and it is possible that the limiting effect of mitochondrial dysfunction on the levels of nucleotides and resulting aberrant RNA and DNA synthesis in part can be responsible for this link. …”
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Advances in lignocellulosic feedstocks for bioenergy and bioproducts by Daniel B. Sulis, Nathalie Lavoine, Heike Sederoff, Xiao Jiang, Barbara M. Marques, Kai Lan, Carlos Cofre-Vega, Rodolphe Barrangou, Jack P. Wang

“…It also explores emerging biotechnologies such as CRISPR-based genome editing informed by machine learning, aimed at improving feedstock traits and reducing the environmental impact of fossil fuel dependence.…”
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The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes by Daria Diodato, Daniele Ghezzi, Valeria Tiranti

“…This is because protein components of the RC are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. …”
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Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats by Alexander Thomas Andreas Weiss, Werner Hecht, Manfred Reinacher

“…Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor 𝛾 locus are also described.…”
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Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis by Jason Kerkvliet, Ramakrishna Edukulla, Moses Rodriguez

“…The RNA-dependent RNA-polymerase, 3Dpol, is an essential component in the picornavirus genome for the replication of single stranded RNA. …”
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The Zebrafish model in dermatology: an update for clinicians by Irene Russo, Emma Sartor, Laura Fagotto, Anna Colombo, Natascia Tiso, Mauro Alaibac

“…Several studies have proved that there is a high level of similarity between human and zebrafish genomes, which encourages the use of zebrafish as a model for understanding human genetic disorders, including cancer. …”
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FLAVONOID BIOSYNTHESIS GENES IN WHEAT by E. K. Khlestkina, O. Y. Shoeva, E. I. Gordeeva

“…Owing to the development of molecular and genomic methods in recent years, considerable progress is made in the understanding of the molecular and genetic mechanisms underpinning flavonoid biosynthesis in bread wheat (Triticum aestivum L.). …”
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Role of FTO in Adipocyte Development and Function: Recent Insights by Myrte Merkestein, Dyan Sellayah

“…In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans. …”
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Dermatophyte Virulence Factors: Identifying and Analyzing Genes That May Contribute to Chronic or Acute Skin Infections by Rebecca Rashid Achterman, Theodore C. White

“…The recent availability of genome sequence information and improved genetic manipulation have enabled researchers to begin to identify and study the role of virulence factors of dermatophytes. …”
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