Novel cycloviruses identified by mining human blood metagenomic data show close relationship to those from animals by Yuanqing Wang, Yuanqing Wang, Xiaojie Jiang, Yuan Xi, Siqi Wei, Songyi Ning, Wen Zhang, Wen Zhang

“…We used viral metagenomics to mine, analyze, and visualize the human blood virome, successfully identifying three new genomes, each encoding Rep and Capsid proteins. These proteins are crucial for viral replication and host-cell interaction: the Rep protein is involved in initiating viral genome replication, while the Capsid protein plays a key role in the assembly of new virions and the virus's ability to interact with host immune systems. …”
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EFFECT OF FLANKING SEQUENCES ON THE ACCURACY OF THE RECOGNITION OF TRANSCRIPTION FACTOR BINDING SITES by T. M. Khlebodarova, D. Yu. Oshchepkov, V. G. Levitsky, O. A. Podkolodnaya, E. V. Ignatieva, E. A. Ananko, I. L. Stepanenko, N. A. Kolchanov

“…The detected features of in vitro selected TF binding sites impose constraints on their use in the development of computer-assisted methods of the recognition of candidate sites in genomic sequences.…”
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Faster model-based estimation of ancestry proportions by Santander, Cindy G., Refoyo Martinez, Alba, Meisner, Jonas

“…We further show that fastmixture runs approximately 30$\times$ faster than ADMIXTURE on both simulated and empirical data from the 1000 Genomes Project such that our model-based approach scales to much larger sample sizes than previously possible.…”
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Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation by Ting Shen, Jing Yu, Bin Xie, Cuiping Huang, Jingjie Cui, Kefu Liu, Chunyu Liu, Chao Chen

“…Summary: Genome-wide association studies (GWASs) have identified numerous genomic loci linked to schizophrenia (SCZ), while their pathogenic mechanisms largely remain unclear. …”
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Global biogeography and projection of antimicrobial toxin genes by Ya Liu, Yu Geng, Yiru Jiang, Jingyu Sun, Peng Li, Yue-zhong Li, Zheng Zhang

“…Results Here, we identified 4400 ATG clusters from 149 families by correlating 10,000 samples worldwide with over 200,000 microbial genome data. We demonstrated that global microbial communities universally encode complex and diverse ATGs, with widespread differences across various habitats. …”
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Productive Entry Pathways of Human Rhinoviruses by Renate Fuchs, Dieter Blaas

“…Currently, complete or partial genome sequences of more than 150 human rhinovirus (HRV) isolates are known. …”
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Natural repeated backcrosses lead to triploidy and tetraploidy in parthenogenetic butterfly lizards (Leiolepis: Agamidae) by Eduard Galoyan, Roman Nazarov, Marie Altmanová, Sergey Matveevsky, Ivan Kropachev, Dmitrij Dedukh, Eugene Iryshkov, Mark Pankin, Natalia Sopilko, Oleg Nikolaev, Nikolai Orlov, Marine Arakelyan, Jiří Klíma, Evgeniya Solovyeva, Tao Nguyen, Lukáš Kratochvíl

“…Within the range of L. guentherpetersi, we found an adult tetraploid male with three L. guttata and one L. reevesii haploid genomes. It probably originated from fertilisation of an unreduced triploid L. guentherpetersi egg by a L. guttata sperm. …”
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Albinism in the Ancient Mediterranean World by John L. Hilton

“… The discovery of DNA in the 20th century and recent biomedical research into the human genome in Southern Africa have shed much light on the diag-nostic, epidemiological, and sociological aspects of albinism. …”
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Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms by M. A. Kleshchev, A. V. Maltseva, E. A. Antropova, P. S. Demenkov, T. V. Ivanisenko, Y. L. Orlov, H. Chao, M. Chen, N. A. Kolchanov, V. A. Ivanisenko

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Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude by Xiaozhen Liu, He Ding, Xiaoxue Zhang, Na Ta, Jinmei Zhao, Qian Zhang, Huiyun Liu, Mengjiao Sun, Xiaoqing Zhang

“…Moreover, a Gangba sheep gastrointestinal microbial genomic catalogue was constructed for the first time, including 1146 metagenome-assembled genomes (MAGs) with completeness > 50% and contamination < 10%, among which, 504 bacterial and 15 archaeal MAGs were of high quality with completeness > 80% and contamination < 10%. …”
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Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples by Oya Cingöz, John M. Coffin

“…The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as endogenous proviruses in mouse genomes. Here, we review the relationship of the human and mouse virus isolates and discuss the potential complications associated with the detection of MLV-like sequences from clinical samples.…”
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DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis by M. Dierssen, M. Martínez de Lagrán

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A Report on a Family with TMTC3-Related Syndrome and Review by Sayeeda Hana, Deepak karthik, Jingxuan Shan, Stephany El Hayek, Lotfi Chouchane, André Megarbane

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Absence of Substantial Copy Number Differences in a Pair of Monozygotic Twins Discordant for Features of Autism Spectrum Disorder by Marina Laplana, José Luis Royo, Anton Aluja, Ricard López, Damiàn Heine-Sunyer, Joan Fibla

“…Recent studies suggest that rare genomic variations, in particular copy number variation (CNV), may account for a significant proportion of the genetic basis of ASD. …”
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Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis by Yihao Sun, Yihao Sun, Guojuan Shi, Jian Yang, Chun-Zhong Zhou, Chuhan Peng, Yu-Hong Luo, Ying Pan, Rui-Qi Wang

“…Our investigation of liver metastases from intestinal cancer uncovered a group of mast cells that might promote metastasis through pathways like inositol phosphate metabolism. Using genomic and clinical data from The Cancer Genome Atlas, we identified specific cell components linked to tumor characteristics and genetics. …”
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening by Wei Jin, Yexuan Deng, John E. La Marca, Emily J. Lelliott, Sarah T. Diepstraten, Christina König, Lin Tai, Valentina Snetkova, Kristel M. Dorighi, Luke Hoberecht, Millicent G. Hedditch, Lauren Whelan, Geraldine Healey, Dan Fayle, Kieran Lau, Margaret A. Potts, Moore Z. Chen, Angus P. R. Johnston, Yang Liao, Wei Shi, Andrew J. Kueh, Benjamin Haley, Jean-Philippe Fortin, Marco J. Herold

“…Our enAsCas12a mouse and accompanying crRNA libraries enhance genome engineering capabilities and complement current CRISPR technologies.…”
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Improvements in pig agriculture through gene editing by Kristin M. Whitworth, Jonathan A. Green, Bethany K. Redel, Rodney D. Geisert, Kiho Lee, Bhanu P. Telugu, Kevin D. Wells, Randall S. Prather

“…Concordant with the developments in genomic sequencing approaches, progress among germline editing efforts is expected to reach feverish pace. …”
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Application of Proteomics to Inflammatory Bowel Disease Research: Current Status and Future Perspectives by Arash Assadsangabi, Caroline A. Evans, Bernard M. Corfe, Alan Lobo

“…Proteomics provides methods for the large-scale study of the proteins encoded by the genome of an organism or a cell, to directly investigate the proteins and pathways involved. …”
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Molecular Genetic Assessment Aids in Clarifying Phylogenetic Status of Iranian Kerman Wild Sheep by Arsen V. Dotsev, Mohammad Hossein Moradi, Tatiana E. Deniskova, Ali Esmailizadeh, Neckruz F. Bakoev, Olga A. Koshkina, Darren K. Griffin, Michael N. Romanov, Natalia A. Zinovieva

“…</i> Additionally, we examined complete mitochondrial genomes and it was demonstrated that the matrilineal ancestor of Kerman sheep belonged to <i>O. vignei</i>. …”
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Expression Profiling of Long Noncoding RNA Splice Variants in Human Microvascular Endothelial Cells: Lipopolysaccharide Effects In Vitro by Imran H. Chowdhury, Hema P. Narra, Abha Sahni, Kamil Khanipov, Casey L. C. Schroeder, Jignesh Patel, Yuriy Fofanov, Sanjeev K. Sahni

“…A majority of LPS-induced lncRNAs are multiexonic and distributed across the genome as evidenced by their presence on all chromosomes. …”
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