Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures by Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim

“…In total, 10 hESC lines were analyzed. For each cell line, genomic DNA was extracted from early and late passages of cell cultures. …”
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Investigation of vitamin D deficiency in girls with growth and development variations—a single center study by Panwang Huang, Panwang Huang, Beilei Zeng, Beilei Zeng, Feng Ren, Yuan Zhou, Yuan Zhou, Ye Li, Ye Li, Yinyin Huang, Yinyin Huang, Xingyu Liu, Xingyu Liu, Jiaxiu Zhou, Jiaxiu Zhou, Yaping Ma, Yaping Ma

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Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells by John D. Blair, Austin Hartman, Fides Zenk, Philipp Wahle, Giovanna Brancati, Carol Dalgarno, Barbara Treutlein, Rahul Satija

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Identification of Novel GCK and HNF4α Gene Variants in Japanese Pediatric Patients with Onset of Diabetes before 17 Years of Age by Rumi Katashima, Mari Matsumoto, Yuka Watanabe, Maki Moritani, Ichiro Yokota

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PIN2-mediated self-organizing transient auxin flow contributes to auxin maxima at the tip of Arabidopsis cotyledons by Patricio Pérez-Henríquez, Shingo Nagawa, Zhongchi Liu, Xue Pan, Marta Michniewicz, Wenxin Tang, Carolyn Rasmussen, Xinping Cui, Jaimie Van Norman, Lucia Strader, Zhenbiao Yang

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GBS-DP: a bioinformatics pipeline for processing data coming from genotyping by sequencing by A. Y. Pronozin, E. A. Salina, D. A. Afonnikov

“…It has been applied to genetic mapping, molecular marker discovery, genomic selection, genetic diversity studies, variety identification, conservation biology and evolutio nary studies. …”
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Machine learning assisted composition design of high-entropy Pb-free relaxors with giant energy-storage by Xingcheng Wang, Ji Zhang, Xingshuai Ma, Huajie Luo, Laijun Liu, Hui Liu, Jun Chen

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Metabolic redundancy and specialisation of novel sulfide-oxidizing Sulfurimonas and Sulfurovum along the brine-seawater interface of the Kebrit Deep by Rayyan Alamoudi, Alan Barozzi, Grégoire Michoud, Marc W. Van Goethem, Charlene Odobel, Yue Chen, Ramona Marasco, Daniele Daffonchio

“…Fifty-four Campylobacterota MAGs were assembled and dereplicated into three distinct groups, with the highest-quality genome retained as representative. These genomes represent novel sulfide-oxidizing species within the Sulfurimonas and Sulfurovum genera, which differ from those found in mildly saline deep-sea sulfidic pools. …”
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Generation of Human-Induced Pluripotent Stem Cells by a Nonintegrating RNA Sendai Virus Vector in Feeder-Free or Xeno-Free Conditions by Chad C. MacArthur, Andrew Fontes, Namritha Ravinder, David Kuninger, Jasmeet Kaur, Matthew Bailey, Antje Taliana, Mohan C. Vemuri, Pauline T. Lieu

“…However, a major obstacle to the use of iPSC for therapeutic applications is the potential of genomic modifications caused by insertion of viral transgenes in the cellular genome. …”
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Nuclear Reprogramming in Mouse Primordial Germ Cells: Epigenetic Contribution by Massimo De Felici

“…The unique capability of germ cells to give rise to a new organism, allowing the transmission of primary genetic information from generation to generation, depends on their epigenetic reprogramming ability and underlying genomic totipotency. Recent studies have shown that genome-wide epigenetic modifications, referred to as “epigenetic reprogramming”, occur during the development of the gamete precursors termed primordial germ cells (PGCs) in the embryo. …”
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Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss by Tatiana G. Markova, Natalia N. Alekseeva, Oxana P. Ryzhkova, Olga L. Shatokhina, Anna A. Orlova, Viktoriia V. Zabnenkova, Olga S. Groznova, Olesya V. Sagaydak, Svetlana S. Chibisova, Alexander V. Polyakov, George A. Tavartkiladze

“…Genetic testing was performed, including whole-genome sequencing for the proband’s son and Sanger sequence analysis for the proband and for all available family members. …”
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A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer’s Disease by Jorge I. Vélez, Dora Rivera, Claudio A. Mastronardi, Hardip R. Patel, Carlos Tobón, Andrés Villegas, Yeping Cai, Simon Easteal, Francisco Lopera, Mauricio Arcos-Burgos

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Deep R-gene discovery in HLB resistant wild Australian limes uncovers evolutionary features and potentially important loci for hybrid breeding by Jianyang Liu, Khushwant Singh, Matthew Huff, Christopher Gottschalk, Michael Do, Margaret Staton, Manjunath L. Keremane, Robert Krueger, Chandrika Ramadugu, Chris Dardick

“…The aim of this study was to gain insight into the genomic features of R-genes in Australian limes, in comparison to susceptible citrus cultivars. …”
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The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB) by Vladimir F. Niculescu, Eugenia R. Niculescu

“…The cells lose their stemness and differentiation potential but persist in proliferation as low-grade polyploids (4n) through defective symmetric cell division (DSCD). Genomic integrity can be restored through homotypic cell and nuclear fusion, resulting in the formation of high-grade polyploids known as multinucleated genome repair syncytia, or by inductive hyperpolyploidization of more than 64n, as observed in single-celled polyploid giant cancer cells. …”
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A Survey of SNP Data Analysis by Xiaojun Ding, Xuan Guo

“…Finally, we discuss the future directions of SNP data analysis for genome-wide association.…”
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Advanced progress in the genetic modification of the oncolytic HSV-1 virus by Mi Zhou, Mi Zhou, Mi Zhou, Zhenyu Shen, Zhenyu Shen, Zhenyu Shen

“…HSV-1 presents several advantages that position it as a leading candidate for oncolytic virotherapies. Its large genome can accommodate insertions over 30 kb or deletions of multiple virulence genes without compromising lytic replication in tumor cells. …”
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The study of organelle DNA variability in alloplasmic barley lines in the NGS era by M. G. Siniauskaya, A. M. Makarevich, I. M. Goloenko, V. S. Pankratov, A. D. Liaudanski, N. G. Danilenko, N. V. Lukhanina, A. M. Shimkevich, O. G. Davydenko

“…Whole chloroplast (cp) and mitochondrial (mt) genome sequences were obtained by the MiSeq System (Illumina). …”
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Influence of human peripheral blood samples preprocessing on the quality of Hi-C libraries by M. M. Gridina, E. Vesna, M. E. Minzhenkova, N. V. Shilova, O. P. Ryzhkova, L. P. Nazarenko, E. O. Belyaeva, I. N. Lebedev, V. S. Fishman

“…The genome-wide variant of the chromatin conformation capture technique (Hi-C) is a powerful tool for revealing patterns of genome spatial organization, as well as for understanding the effects of their disturbance on disease development. …”
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Alien introgressions and chromosomal rearrangements do not affect the activity of gliadin-coding genes in hybrid lines of Triticum aestivum L. × Aegilops columnaris Zhuk by A. Yu. Novoselskaya-Dragovich, A. A. Yankovskaya, E. D. Badaeva

“…In spite of losing a part of its long arm and combination with a non-homologous chromosome of a different genome (4BL), chromosome 1D was fully functioning. …”
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Breeding for postharvest physiological deterioration in cassava: problems and strategies by Wilton Mbinda, Asunta Mukami

“…With its extensive genomic resources including the public release of cassava reference genome sequence assembly and other and resources, and innovative plant breeding technologies, the crop offers an excellent opportunity to serve as a model to address postharvest spoilage and improve food security. …”
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