Showing 2,721 - 2,740 results of 5,161 for search '"genomics"', query time: 0.07s Refine Results
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    Network-assisted target identification for haploinsufficiency and homozygous profiling screens. by Sheng Wang, Jian Peng

    Published 2017-06-01
    “…Chemical genomic screens have recently emerged as a systematic approach to drug discovery on a genome-wide scale. …”
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  8. 2728

    Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha by Senqin Hou, Shibin Yang, Wenqin Bai

    Published 2025-01-01
    “…However, the lack of precise and efficient genome editing tools severely hinders the construction of cell factories. …”
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    Article
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    IGN: Invariable gene set-based normalization for chromatin accessibility profile data analysis by Shengen Shawn Hu, Hai-Hui Xue, Chongzhi Zang

    Published 2025-01-01
    “…Chromatin accessibility profiles generated using ATAC-seq or DNase-seq carry functional information of the regulatory genome that controls gene expression. Appropriate normalization of ATAC-seq and DNase-seq data is essential for accurate differential analysis when studying chromatin dynamics. …”
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    Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

    Published 2021-06-01
    “…The correct deployment of genetic programs for development and differentiation relies on finely coordinated regulation of specific gene sets. Genomic regulatory elements play an exceptional role in this process. …”
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  13. 2733

    Resistify: A Novel NLR Classifier That Reveals Helitron-Associated NLR Expansion in Solanaceae by Moray Smith, John T Jones, Ingo Hein

    Published 2025-01-01
    “…Nucleotide-binding domain leucine-rich repeat (NLR) proteins are a key component of the plant innate immune system. In plant genomes, NLRs exhibit considerable presence/absence variation and sequence diversity. …”
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  14. 2734

    Rational Primer and Probe Construction in PCR-Based Assays for the Efficient Diagnosis of Drifting Variants of SARS-CoV-2 by Divya RSJB Rana, Nischal Pokhrel, Santosh Dulal

    Published 2022-01-01
    “…The genome sequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been evolving via genomic drifts resulting in “emerging/drifting variants” circulating worldwide. …”
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    Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins by E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A.  D.  Gavrilenko, T.  V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko

    Published 2023-01-01
    “…The ANDSystem software package was used to reconstruct and evaluate the statistical significance of the pathways HCV could potentially use to regulate 32 hypermethylated genes in HCC, including both oncosuppressor and protumorigenic ones identified by genome-wide analysis of DNA methylation. The reconstructed pathways included those affecting protein-protein interactions (PPI), gene expression, protein activity, stability, and transport regulations, the expression regulation pathways being statistically significant. …”
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    Bovine mycoplasmosis occurrence on livestock farms in the Russian Federation for 2015–2018 by Mohammad Abed Alhussen, A. A. Nesterov, V. V. Kirpichenko, S. P. Yatsentyuk, A. V. Sprygin, O. P. Byadovskaya, A. V. Kononov

    Published 2020-06-01
    “…As a result, M. bovis genome was detected in 10.1% of the samples, M. bovigenitalium genome was detected in 8.6% of the samples and М. dispar genome was detected in 37.15% of the samples. …”
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