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2561
In silico design of an epitope-based vaccine ensemble for fasliolopsiasis
Published 2025-01-01Get full text
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2562
Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024
Published 2025-02-01“…Genome sequence analysis was performed with CLC Genomics Workbench, and genotyping and sequence alignment were carried out using the Nextclade platform. …”
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Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint
Published 2025-01-01“…Clinical application was assessed using The Cancer Genome Atlas (TCGA) dataset, with Best Overall Response (BOR) serving as the clinical efficacy measure. …”
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2566
Targeting Nrf2/KEAP1 signaling pathway using bioactive compounds to combat mastitis
Published 2025-02-01Get full text
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2570
Peripheral blood miRNAs are associated with airflow below threshold in children with asthma
Published 2025-01-01Get full text
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2572
The Progression of Mycosis Fungoides During Treatment with Mogamulizumab: A BIO-MUSE Case Study of the Tumor and Immune Response in Peripheral Blood and Tissue
Published 2025-01-01“…<b>Methods:</b> We applied 10× genomics-based single-cell RNA sequencing to CD3+ peripheral T-cells, combined with T-cell receptor sequencing, to samples collected at multiple timepoints during the progression of the disease. …”
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2573
The potential of the amaranth collection maintained at VIR in the context of global plant breeding and utilization trends
Published 2024-11-01“…Despite the great potential of amaranth, little research has been dedicated to the study of its genomics, concentrating mainly on the identification of its species diversity. …”
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2574
Atypical Mucin Expression Predicts Worse Overall Survival in Resectable Pancreatic Ductal Adenocarcinoma
Published 2022-01-01“…Survival analysis was also performed in the Queensland Centre for Medical Genomics (QCMG, n=70) PDAC cohort to verify the conclusion. …”
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2575
Machine learning based predictive model and genetic mutation landscape for high-grade colorectal neuroendocrine carcinoma: a SEER database analysis with external validation
Published 2025-01-01“…This study was designed to construct a risk model based on comprehensive clinical and mutational genomics data to facilitate clinical decision making.MethodsA retrospective analysis was conducted using data from the Surveillance, Epidemiology, and End Results (SEER) database, spanning 2000 to 2019. …”
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Advances in plant male sterility for hybrid seed production: an overview of conditional nuclear male sterile lines and biotechnology-based male sterile systems
Published 2025-02-01“…Here we review environment-sensitive genic male sterility (EGMS) and biotechnology-based male sterility systems and describe the underlying molecular mechanisms. Advances in crop genomics and discovery of a large number of nuclear genes governing anther/pollen development, which are shared across species, are helping design diverse types of male sterile lines suitable for different crop species and situations. …”
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Causal associations between iron levels in subcortical brain regions and psychiatric disorders: a Mendelian randomization study
Published 2025-01-01“…The genetic instrumental variables linked to iron levels and psychiatric disorders were derived from the genome-wide association studies data of the UK Biobank Brain Imaging and Psychiatric Genomics Consortium. …”
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Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis
Published 2020-01-01“…Three datasets (GSE95233, GSE57065, and GSE28750) associated with sepsis were downloaded from the public functional genomics data repository Gene Expression Omnibus. Differentially expressed genes (DEGs) were identified using R packages (Affy and limma). …”
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Novel protein-based prognostic signature linked to immunotherapeutic efficiency in ovarian cancer
Published 2024-09-01“…Methods The workflow was demonstrated based on the Reverse Phase Protein Array (RPPA) and RNA-sequencing profiles of ovarian cancer patients from The Cancer Genome Atlas (TCGA). The algorithm began by clustering patients using immune-related gene sets, which allowed us to identify immune-related proteins of interest. …”
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