The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment by Yi-Cheng Chang, Siow-Wey Hee, Meng-Lun Hsieh, Yung-Ming Jeng, Lee-Ming Chuang

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A robust transfer learning approach for high-dimensional linear regression to support integration of multi-source gene expression data. by Lulu Pan, Qian Gao, Kecheng Wei, Yongfu Yu, Guoyou Qin, Tong Wang

“…This can be effectively applied in genomics when we learn the gene associations in a target tissue, and data from other tissues can be integrated. …”
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The role of chromatin state in intron retention: A case study in leveraging large scale deep learning models. by Ahmed Daoud, Asa Ben-Hur

“…By providing pre-trained models that can be fine-tuned for specific applications, they enable researchers to create accurate models with minimal effort and computational resources. Large scale genomics deep learning models come in two flavors: the first are large language models of DNA sequences trained in a self-supervised fashion, similar to the corresponding natural language models; the second are supervised learning models that leverage large scale genomics datasets from ENCODE and other sources. …”
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Protocol for direct cDNA cap analysis of gene expression for paired-end patterned flow cell sequencing by Diane Delobel, Hiromi Nishiyori-Sueki, Ilaria Nisoli, Hideya Kawaji, Pauline Robbe, Piero Carninci, Hazuki Takahashi

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From Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi by Asanka Madhushan, Dulan Bhanuka Weerasingha, Evgeny Ilyukhin, Paul W. J. Taylor, Amila Sandaruwan Ratnayake, Jian-Kui Liu, Sajeewa S. N. Maharachchikumbura

“…The study of pathogen evolution has been transformed by advancements in molecular biology, genomics, and bioinformatics, utilizing methods like next-generation sequencing, comparative genomics, transcriptomics and population genomics. …”
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Toward measurements of absolute membrane potential in Bacillus subtilis using fluorescence lifetime by Debjit Roy, Xavier Michalet, Evan W. Miller, Kiran Bharadwaj, Shimon Weiss

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Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

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Automatic morphology phenotyping of tetra- and hexaploid wheat spike using computer vision methods by A. Yu. Pronozin, A. A. Paulish, E. A. Zavarzin, A. Yu. Prikhodko, N. M. Prokhoshin, Yu. V. Kruchinina, N. P. Goncharov, E. G. Komyshev, M. A. Genaev

“…The modern cultivated wheat species originated from three wild diploid ancestors as a result of several rounds of genome doubling and are represented by di-, tetra- and hexaploid species. …”
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Growth hormone deficiency and secondary adrenal insufficiency in petrified ears syndrome: a case report and literature review by Sebastiano Recalcati, Alberto Vassallo, Marta Villanova, Roberto Lanzi, Marco Losa, Maria Grazia Patricelli, Paola Carrera, Fabrizio Fantini

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Biomarkers of Joint Damage in Osteoarthritis: Current Status and Future Directions by Rajkamal Kumavat, Vijay Kumar, Rajesh Malhotra, Hemant Pandit, Elena Jones, Frederique Ponchel, Sagarika Biswas

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Targeted Next-Generation Resequencing of Gene Identifies Novel Multiple Variants Pattern in Severe Hereditary Factor V Deficiency by Piotr K. Janicki, Sonia Vaida, Hamid A. B. AL-Mondhiry

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Differential Stress Responses to Rice Blast Fungal Infection Associated with the Vegetative Growth Phase in Rice by Takuma Koyama, Takumi Tezuka, Atsushi J. Nagano, Jiro Murakami, Takanori Yoshikawa

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Blood-based prognostic scores and early dynamics under immunotherapy to select patients with metastatic solid tumors for continuing immune check-point inhibition: a prospective lon... by Javier García-Corbacho, Alberto Indacochea, Iván Victoria, Débora Moreno, Laura Angelats, Azucena E. González Navarro, Laura Mezquita, Fara Brasó-Maristany, Patricia Galván, Begoña Mellado, Nuria Viñolas, Tamara Sauri, Miquel Nogué, Barbara Adamo, Joan Maurel, Estela Pineda, Lydia Gaba, Oscar Reig, Neus Basté, Esther Sanfeliu, Manel Juan, Aleix Prat, Francesco Schettini

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I’ll Show You Mine, If You Show Me Yours

“…The human genome dominated science news last week. Both Science and Nature lead this week with articles about the simultaneous publication of the human genome sequence by the private company Celera Genomics and the publicly funded Human Genome Project (HGP).…”
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Major Histocompatibility Class II Pathway Is Not Required for the Development of Nonalcoholic Fatty Liver Disease in Mice by Gilles Willemin, Catherine Roger, Armelle Bauduret, Kaori Minehira

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Characterization of the Escherichia coli Antifungal Protein PPEBL21 by V. Yadav, R. Mandhan, M. Kumar, J. Gupta, G. L. Sharma

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Employing the Oncolytic Vesicular Stomatitis Virus in Cancer Virotherapy: Resistance and Clinical Considerations by Alaa A. Abdelmageed, Stephen Dewhurst, Maureen C. Ferran

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In-Depth Exploration of Human Gut Microbiota: A Review by Maliha Rashid, Dwaipayaan Sinha, Muhammad Usama, Mariam Badam, Maryam Idrees, Saiqa Noureen, Reem Nadeem, Muhammad Mustajab Khan, Shakira Ghazanfar

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Restructuring BOD : COD Ratio of Dairy Milk Industrial Wastewaters in BOD Analysis by Formulating a Specific Microbial Seed by Purnima Dhall, T. O. Siddiqi, Altaf Ahmad, Rita Kumar, Anil Kumar

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Qualitative Parameters of the Colonic Flora in Patients with HNF1A-MODY Are Different from Those Observed in Type 2 Diabetes Mellitus by Sandra Mrozinska, Piotr Radkowski, Tomasz Gosiewski, Magdalena Szopa, Malgorzata Bulanda, Agnieszka H. Ludwig-Galezowska, Iwona Morawska, Agnieszka Sroka-Oleksiak, Bartlomiej Matejko, Przemyslaw Kapusta, Dominika Salamon, Maciej T. Malecki, Pawel Wolkow, Tomasz Klupa

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