Showing 2,201 - 2,220 results of 5,161 for search '"genomics"', query time: 0.07s Refine Results
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    True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair by Nicolas Le May, Jean-Marc Egly, Frédéric Coin

    Published 2010-01-01
    “…During NER, more than 30 polypeptides cooperate to recognize, incise, and excise a damaged oligonucleotide from the genomic DNA. Recent papers reveal an additional and unexpected role for the NER factors. …”
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    The DNA Replication Stress Hypothesis of Alzheimer’s Disease by Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov

    Published 2011-01-01
    “…However, this theory seems to require some inputs in accordance with the generally recognized amyloid cascade theory as well as to explain causes and consequences of genomic instability (aneuploidy) in the AD brain. …”
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    Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

    Published 2025-02-01
    “…Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. Whereas point mutation rates vary with genomic location and local DNA features, the role of genome architecture in the formation and evolutionary dynamics of CNVs is poorly understood. …”
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    mtlA, a novel typing gene offering enhanced resolution for pandemic Vibrio species by Lei Zhou, Danlei Liu, Zilong Zhang, Yongqiang Zhu, Huajun Zheng

    Published 2025-02-01
    “…In summary, these findings validated the potential typing application of the mtlA gene in Vibrio species.IMPORTANCEVibrio is a collection of gram-negative bacteria characterized by possessing two chromosomes, which exhibit numerous shared biological and genomic traits. Around 13 species of Vibrio are known to cause infections in humans. …”
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