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461
Breeding for postharvest physiological deterioration in cassava: problems and strategies
Published 2022-05-01“…With its extensive genomic resources including the public release of cassava reference genome sequence assembly and other and resources, and innovative plant breeding technologies, the crop offers an excellent opportunity to serve as a model to address postharvest spoilage and improve food security. …”
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462
Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease
Published 2025-01-01“…Here, we genotype 312,731 polymorphic STR tracts genome-wide using PCR-free whole genome sequencing data from 2981 individuals (1489 AD case and 1492 control individuals). …”
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463
A New Prognostic Indicator of Immune Microenvironment and Therapeutic Response in Lung Adenocarcinoma Based on Peroxisome-Related Genes
Published 2022-01-01“…However, the prognostic values of peroxisome-related genes (PRGs) were rarely reported. Genomic sequence, mutation, and clinical data of 535 LUAD tissues were obtained from TCGA data sets. …”
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464
An evaluation of the severe acute respiratory infection surveillance system in Ireland
Published 2025-02-01“…Time to receipt of whole genome sequencing (WGS) results was 40 days (IQR 30–61). …”
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465
Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD.
Published 2025-02-01“…We performed the first whole-genome sequence association analysis of comorbid GERD and COPD in 12,438 multi-ancestry participants. …”
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466
Pea (Pisum sativum L.): the uneasy fate of the first genetical object
Published 2015-07-01“…Meanwhile, we await the completion of pea nuclear genome sequencing in 2016. For working out new molecular markers in pea, the synteny of its genome to the sequenced genome of Medicago truncatula is extensively used. …”
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467
“Sichuanvirus”, a novel bacteriophage viral genus, able to lyse carbapenem-resistant Klebsiella pneumoniae
Published 2025-01-01“…We also obtained three bacterial mutants resistant to the phage and performed genome sequencing for them. We therefore discovered that the interruption of a capsular polysaccharide biosynthesis-related gene wcaJ by insertion sequences mediated the resistance to this phage. …”
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468
Pathogenicity of avian reovirus variant in the immune organs of broiler chicks
Published 2025-03-01“…In this study, an ARV strain (Chicken/XJ/China/2022/01/16) was isolated from arthritic broiler chicks in Xinjiang province and whole genome sequencing of the ARV strain was performed using next generation sequencing (NGS) technology, and sequence analysis showed that the strain was a type V variant of the ARV gene. …”
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469
Comparison of SNP Variation and Distribution in Indigenous Ethiopian and Korean Cattle (Hanwoo) Populations
Published 2012-09-01“…Although a large number of single nucleotide polymorphisms (SNPs) have been identified from the bovine genome-sequencing project, few of these have been validated at large in Bos indicus breeds. …”
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470
Decomposition of the pangenome matrix reveals a structure in gene distribution in the Escherichia coli species
Published 2025-01-01“…ABSTRACT Thousands of complete genome sequences for strains of a species that are now available enable the advancement of pangenome analytics to a new level of sophistication. …”
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471
A chemical genetic screen with the EXO70 inhibitor Endosidin2 uncovers potential modulators of exocytosis in Arabidopsis
Published 2024-06-01“…Through a whole‐genome sequencing‐based mapping strategy, 14 nonallelic es2s mutants were mapped and the candidate mutations reported here. …”
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472
Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae
Published 2025-01-01“…The clones were categorised into two groups based on their respiratory competence or deficiency, the latter associated with mtDNA loss, an event seemingly linked to FCNZ and heat tolerance. Genome sequencing and ploidy‐level analysis of all strains revealed aneuploidies, copy number variations (CNVs), and single nucleotide polymorphisms (SNPs). …”
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473
Adaptive evolution of stress response genes in parasites aligns with host niche diversity
Published 2025-01-01“…We comparatively investigated antioxidant, heat shock, osmoregulatory, and behaviour-related genes (foraging) in two model parasitic flatworm lineages with contrasting ecological diversity, Cichlidogyrus and Kapentagyrus (Platyhelminthes: Monopisthocotyla), through whole-genome sequencing of 11 species followed by in silico exon bait capture as well as phylogenetic and codon analyses. …”
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474
Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal
Published 2019-01-01“…In the present study, we analyzed by whole genome sequencing (WGS) all clinical, animal, food, and environmental isolates received up to 2017 in the Portuguese Reference Laboratories. …”
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475
Genome-wide characterization of the MADS-box gene family in Paeonia ostii and expression analysis of genes related to floral organ development
Published 2025-01-01“…A total of 857 SSRs were identified by analysing the genome sequences of identified genes. We additionally created protein‒protein interaction networks for PoMADS proteins and analysed proteins that could interact among PoMADSs in Arabidopsis thaliana and grape. …”
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476
Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss
Published 2024-03-01“…Genetic testing was performed, including whole-genome sequencing for the proband’s son and Sanger sequence analysis for the proband and for all available family members. …”
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477
Subtle genomic differences in Klebsiella pneumoniae sensu stricto isolates indicate host adaptation
Published 2025-06-01“…A total of 128 KpI strains (bovine n = 65; human n = 63) were whole genome sequenced and human and bovine strains were compared based on phylogenomics, the pangenome, mobile genetic elements, and differential gene abundance. …”
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478
Insufficient gene expression and lost gene regulatory network may underlie the mechanism of Hirschsprung Disease in 5p–syndrome
Published 2025-02-01“…Here, we conducted a study on two patients with CDC and HSCR using whole genome sequencing (WGS) analyses. Our WGS data confirmed the deletion regions on 5p associated with CDC and indicated potential unknown genetic mechanisms underlying HSCR. …”
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479
Pseudomonas azotoformans and Pseudomonas putida: Novel kiwifruit-native biological control agents against Pseudomonas syringae pv. actinidiae
Published 2025-02-01“…In vitro metabolic analysis together with genome sequencing and annotation revealed siderophore production, in particular pyoverdine, which may limit iron availability to the pathogen. …”
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480
The study of organelle DNA variability in alloplasmic barley lines in the NGS era
Published 2020-03-01“…Whole chloroplast (cp) and mitochondrial (mt) genome sequences were obtained by the MiSeq System (Illumina). …”
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